Ursus americanus (American black bear): 123787224
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Entry
123787224 CDS
T07931
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar00260
Glycine, serine and threonine metabolism
uar00630
Glyoxylate and dicarboxylate metabolism
uar00670
One carbon pool by folate
uar01100
Metabolic pathways
uar01200
Carbon metabolism
uar01230
Biosynthesis of amino acids
uar01240
Biosynthesis of cofactors
uar01523
Antifolate resistance
uar04981
Folate transport and metabolism
Module
uar_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
123787224 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
123787224 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
123787224 (SHMT2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
123787224 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
123787224 (SHMT2)
Enzymes [BR:
uar01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
123787224 (SHMT2)
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Paralog
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Motif
Pfam:
SHMT
Motif
Other DBs
NCBI-GeneID:
123787224
NCBI-ProteinID:
XP_045645744
UniProt:
A0A452S4T9
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All DBs
Position
Unknown
AA seq
504 aa
AA seq
DB search
MLPFSLLWATRPLQRCGQLVRMAIRCQHSEVAQTQTGEATRGWTGQESLSDSDPEMWELL
QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGTEVVDEVELLCQ
RRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
KRVSATSIFFESMPYKLNPKTGLIDYDQLALTARLFRPRLIIAGTSAYARLIDYARMREV
CDEVRAHLLADMAHISGLVAAKVIPSPFKHADVVTTTTHKTLRGARSGLIFYRKGTRAVD
PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYALQVLKNARA
MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVSIGLAVKSKTAKLQDFKSFLLKDPETSH
RLADLRQRVEQFARAFPMPGFDER
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atgctgcccttctctttgctctgggcgactcggcctctgcagagatgtggtcagctggtc
aggatggccatccggtgccagcacagtgaggtggcccagacccagactggagaagcaacc
aggggctggacaggccaggagagtctgtcagacagtgaccctgagatgtgggagctgctg
cagagggagaaggacaggcagtgtcgtggcctggagctcattgcctcagagaacttctgc
agccgagctgcgctggaggccctggggtcctgtctgaacaacaagtactcggagggttat
cctggcaagaggtactacggaggcacagaggtagtggatgaagttgagctgctgtgtcag
cgcagggccttggaggccttcgacctggatcccgcgcagtggggagtcaatgtgcagccg
tactcgggctcgccggctaatctggccgcctacacggccctcctgcagccccatgaccga
atcatggggctggacttgcccgatgggggccatctgactcacggctacatgtctgatgtc
aagcgggtctcagccacgtccatcttctttgagtccatgccctataagctcaatcctaaa
accggcctcatcgactacgaccagctggcgctgactgcgcggctcttccgcccgcggctc
attattgctggtaccagtgcctacgcgcgcctcattgactacgcccgcatgagagaggtg
tgtgatgaagtcagggcacacctactggcagacatggcccacatcagtggcctggtggct
gccaaggtgatcccctcacctttcaagcatgcggatgttgtcaccaccaccactcacaag
acccttcgaggggccaggtctggactcatcttctaccggaaggggactcgggctgtggac
cccaagactggccgggagatcccgtacacatttgaggaccgaatcaactttgccgtgttt
ccatccctgcagggggggccccacaaccatgccattgctgccgtggctgtggccctaaag
caggcctgcacccccatgttccgggagtacgccctgcaggttctgaagaatgctcgggcc
atggctgatgccctgctagagcgaggctactcactcgtgtctggtggcaccgacaaccac
ctagtgctcgtggatctgcggcccaagggcctggatggagctcgggctgagcgggtgctg
gaactggtgtccatcacagccaacaagaacacctgtcctggagaccgaagtgccatcaca
cctgggggcctgcggctcggggccccagccctgacctctcgacagttccgcgaggatgac
ttccggagagttgtggacttcatagatgaaggtgtcagcatcggcttggcggtgaagagc
aagactgccaaactccaggatttcaaatccttcctgctcaaggacccagaaacaagtcat
cggctggctgacctcaggcaacgggtggagcagtttgccagggccttccccatgcctggt
tttgatgagcgctga
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