Ursus americanus (American black bear): 123787859
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Entry
123787859 CDS
T07931
Symbol
HPSE
Name
(RefSeq) heparanase isoform X1
KO
K07964
heparanase [EC:
3.2.1.166
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar00531
Glycosaminoglycan degradation
uar01100
Metabolic pathways
uar05205
Proteoglycans in cancer
Module
uar_M00078
Heparan sulfate degradation
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00531 Glycosaminoglycan degradation
123787859 (HPSE)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
123787859 (HPSE)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
00536 Glycosaminoglycan binding proteins [BR:
uar00536
]
123787859 (HPSE)
Enzymes [BR:
uar01000
]
3. Hydrolases
3.2 Glycosylases
3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
3.2.1.166 heparanase
123787859 (HPSE)
Glycosaminoglycan binding proteins [BR:
uar00536
]
Heparan sulfate / Heparin
Enzymes
123787859 (HPSE)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Glyco_hydro_79n
Motif
Other DBs
NCBI-GeneID:
123787859
NCBI-ProteinID:
XP_045646762
LinkDB
All DBs
Position
Unknown
AA seq
540 aa
AA seq
DB search
MLRRWKPGLPLLLLLGPLGPFSPGALAGPEQAEDVVELDFSTERPVHLVSPAFLSFTIDA
NLATDPRFLTFLGSPKLRTLARGLSPAYLRFGGTKTDFLIFDPQKEPTFEERSYWQSQVN
QDICKSGSLPSDVEKKLQLEWPFQEQLLLREQHQKKFKNSTYSKSSVDMLYAFANCSGLD
LIFGLNALLRTADLQWNSSNAQLLLDYCSSKNYNISWELGNEPNSFRKKAGIFIDGLQLG
EDFVKLHKLLGKTAFKTSHLYGPDVGQPRGKTVKILRSFLKAGGEVIDSVTWHHYYLNGR
IATKEDFLNPDVLDTFTSSVQKVFQVVEETRPHKKVWLGETSSAYGGGAPLLSNTFVAGF
MWLDKLGLSARMGIEVVMRQVLFGAGNYHLVDENFEPLPDYWLSLLFKKLVGTSVFMASV
KGPDRNKLRVYLHCTNVNHPRYKEGDLTLYALNLHNVTKRLRLPSHLFDKQVDKYLIKPL
GLDGLLSKSVQLNGRTLKMVDDHTLPALTEKTLRPGSSLGLPAFSYGFFVIRNAKVTACL
NT seq
1623 nt
NT seq
+upstream
nt +downstream
nt
atgctgcggcgctggaagccggggctgccgctgctgctgctcctgggccctctcggtccc
ttctccccgggcgccctggcgggacccgagcaggccgaggacgttgtggagctggacttc
tccaccgagcggccggtgcacctggtgagtccggcgttcctgtccttcaccatcgacgcc
aacctggccacggacccgcggttcctcaccttcctgggttctccaaagcttcgcactttg
gctagaggcttgtctccagcatacctgcgatttggtggcaccaagacggactttctcatt
ttcgatccccaaaaagaaccgacctttgaagagaggagttactggcagtctcaagtcaac
caggatatttgcaaatctggctccctcccttctgatgtagagaagaagttacagttggaa
tggcccttccaggaacaattgctgctcagagaacagcatcagaaaaagttcaagaacagc
acttactcgaaaagctccgtggatatgctgtatgcttttgcaaattgctcaggactggac
ttgatctttgggctaaatgccttactacgaacagcagacttgcagtggaacagctctaac
gctcagttgctcctggactattgctcttccaagaattataacatttcttgggaactaggc
aatgaacctaacagtttccggaagaaggctggtattttcatcgatggattgcagttagga
gaagattttgtcaagttgcataaacttctaggaaaaaccgctttcaaaacttcgcatctc
tatgggcctgatgttggccagcctcgaggaaagacggtcaagatactgaggagtttcctg
aaggctggcggagaagtgattgattcggttacctggcaccactactacttgaatggacga
attgctaccaaagaagatttcctaaaccctgatgtgttggacacttttacttcatctgtg
caaaaagttttccaggttgttgaggagacccgaccccacaagaaggtttggttaggagaa
acgagctctgcgtatgggggtggagcgcccttgctgtctaacacctttgtggctggcttt
atgtggctggataaattgggcctgtcggccagaatgggcatagaagtggtgatgaggcaa
gtgctcttcggagccggaaactaccacttagtggatgaaaacttcgaacctctacctgat
tattggctatctcttctgttcaagaaattggtaggcaccagtgtgtttatggcaagtgtg
aaaggtccagacagaaataaacttcgagtataccttcattgcaccaacgtcaaccaccca
aggtataaagaaggagatttaactctgtatgctttaaacctccataatgtcaccaaacgc
ctgaggctgccctctcatctgtttgacaaacaagtggacaaatacctcataaaaccttta
gggcttgatggattgctttccaaatccgtgcagctcaatggtcgaactctgaagatggtg
gacgatcacaccctcccggctttgacagaaaaaactctccgcccaggaagttcactgggc
ttgccagctttctcatatggattttttgtgataagaaatgccaaagttactgcttgcctc
tga
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