Ursus americanus (American black bear): 123787974
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Entry
123787974 CDS
T07931
Symbol
HSPA5
Name
(RefSeq) endoplasmic reticulum chaperone BiP
KO
K09490
endoplasmic reticulum chaperone BiP [EC:
3.6.4.10
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar03060
Protein export
uar04141
Protein processing in endoplasmic reticulum
uar04612
Antigen processing and presentation
uar04918
Thyroid hormone synthesis
uar05012
Parkinson disease
uar05014
Amyotrophic lateral sclerosis
uar05020
Prion disease
uar05022
Pathways of neurodegeneration - multiple diseases
uar05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03060 Protein export
123787974 (HSPA5)
04141 Protein processing in endoplasmic reticulum
123787974 (HSPA5)
09150 Organismal Systems
09151 Immune system
04612 Antigen processing and presentation
123787974 (HSPA5)
09152 Endocrine system
04918 Thyroid hormone synthesis
123787974 (HSPA5)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
123787974 (HSPA5)
05014 Amyotrophic lateral sclerosis
123787974 (HSPA5)
05020 Prion disease
123787974 (HSPA5)
05022 Pathways of neurodegeneration - multiple diseases
123787974 (HSPA5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
123787974 (HSPA5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
uar03110
]
123787974 (HSPA5)
04131 Membrane trafficking [BR:
uar04131
]
123787974 (HSPA5)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
uar04147
]
123787974 (HSPA5)
Enzymes [BR:
uar01000
]
3. Hydrolases
3.6 Acting on acid anhydrides
3.6.4 Acting on acid anhydrides to facilitate cellular and subcellular movement
3.6.4.10 non-chaperonin molecular chaperone ATPase
123787974 (HSPA5)
Chaperones and folding catalysts [BR:
uar03110
]
Heat shock proteins
HSP70 / DNAK
123787974 (HSPA5)
Membrane trafficking [BR:
uar04131
]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
ER-Golgi intermediate compartment (ERGIC) proteins
123787974 (HSPA5)
Autophagy
ER-phagy
ER stress-related proteins
123787974 (HSPA5)
Exosome [BR:
uar04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
123787974 (HSPA5)
Exosomal proteins of other body fluids (saliva and urine)
123787974 (HSPA5)
Exosomal proteins of colorectal cancer cells
123787974 (HSPA5)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HSP70
MreB_Mbl
Hydantoinase_A
FtsA
DDR
FGGY_C
ParM_N
Motif
Other DBs
NCBI-GeneID:
123787974
NCBI-ProteinID:
XP_045646902
UniProt:
A0A452RGZ4
LinkDB
All DBs
Position
Unknown
AA seq
654 aa
AA seq
DB search
MKLSLVAAVLLLLGAARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNR
ITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVV
EKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQ
RQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNG
VFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALS
SQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIV
LVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVC
PLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLG
TFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIER
MVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEE
KIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGDEEPADKDEL
NT seq
1965 nt
NT seq
+upstream
nt +downstream
nt
atgaagctgtccctggtggctgcggtgctgctgctcctcggcgcggcgcgggccgaggag
gaggacaagaaggaggacgtgggcacggtggtcggcatcgacttggggaccacctactcc
tgcgtcggggtgttcaagaacggccgcgtggagatcatcgccaacgatcagggcaaccgc
atcacgccgtcttatgtggccttcactcctgaaggggagcgtttgatcggcgatgccgcc
aagaaccagctcacctccaaccctgagaacacggtcttcgacgccaagcggctcatcggc
cgcacatggaacgacccgtctgtgcagcaggacatcaagttcctgcctttcaaggttgtt
gagaagaaaactaaaccatacattcaagttgatattggaggtgggcaaacaaagacattt
gcccctgaagaaatttctgccatggttctcactaaaatgaaggaaactgcagaggcttat
ttaggaaagaaggttacccatgcagttgttaccgtaccagcctatttcaatgatgcccaa
cgccaggcaaccaaagatgcaggaactattgctggattgaatgttatgaggatcattaat
gagcctacagcagccgctattgcttatggcttggataagcgggaaggggagaagaatatc
ctggtgtttgacttgggtggtggaacctttgatgtgtctcttctcaccattgacaatggt
gtcttcgaagtcgtggctactaatggagatactcatctggggggagaagactttgaccaa
cgtgtcatggaacacttcatcaaactctacaaaaagaagactggcaaagatgttaggaaa
gacaacagagctgtgcagaaactccggcgggaggtagaaaaggccaaacgggccctgtct
tctcaacatcaggcaagaattgaaattgagtctttctatgaaggggaagacttctctgag
actctgactcgggccaaatttgaagaactaaatatggatctgttccgttctaccatgaag
cctgttcagaaggtgctggaggattctgacttaaagaagtctgatattgatgaaattgtt
cttgttggtggctctactcgaatcccaaagattcaacaactggttaaagagttcttcaat
ggcaaggagccatcccgtggcatcaacccagatgaggctgtagcatacggtgctgctgtc
caggctggtgtactctctggtgatcaggatacaggtgatctggtactgcttgatgtatgt
ccccttacacttggtattgaaactgtgggaggtgtcatgaccaaactgattccaaggaac
actgtggtgcccacaaagaagtctcagatcttttctacagcttctgataaccaaccaact
gttacaatcaaggtctatgaaggtgaacgacccctgacaaaagacaatcaccttctggga
acttttgatctgactggaattcctcctgctccccgtggggtcccacagattgaagtcacc
tttgagatagatgtgaatggcattcttcgagtgacagctgaagacaaaggtacaggcaac
aaaaataagattacaattacgaatgaccaaaatcgcctgacacctgaagagattgaaagg
atggttaatgatgctgagaagtttgccgaggaagacaaaaagctcaaggagcgcattgat
actagaaatgaattggaaagctatgcctattctctaaaaaatcagattggagataaagaa
aagctgggaggtaaactctcctctgaggataaggagaccatggaaaaagctgtagaggaa
aagattgaatggctagaaagtcatcaagatgctgacattgaagatttcaaagctaaaaag
aaggaactagaagaaattgttcagccaattatcagcaaactctatggaagtgcaggccct
cccccaactggtgatgaggaaccagcagacaaagatgagttgtag
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