KEGG   Ursus americanus (American black bear): 123788629
Entry
123788629         CDS       T07931                                 
Symbol
IL12B
Name
(RefSeq) interleukin-12 subunit beta
  KO
K05425  interleukin 12B
Organism
uar  Ursus americanus (American black bear)
Pathway
uar04060  Cytokine-cytokine receptor interaction
uar04620  Toll-like receptor signaling pathway
uar04622  RIG-I-like receptor signaling pathway
uar04625  C-type lectin receptor signaling pathway
uar04630  JAK-STAT signaling pathway
uar04658  Th1 and Th2 cell differentiation
uar04936  Alcoholic liver disease
uar04940  Type I diabetes mellitus
uar05133  Pertussis
uar05134  Legionellosis
uar05140  Leishmaniasis
uar05142  Chagas disease
uar05143  African trypanosomiasis
uar05145  Toxoplasmosis
uar05146  Amoebiasis
uar05152  Tuberculosis
uar05162  Measles
uar05164  Influenza A
uar05168  Herpes simplex virus 1 infection
uar05171  Coronavirus disease - COVID-19
uar05200  Pathways in cancer
uar05205  Proteoglycans in cancer
uar05321  Inflammatory bowel disease
uar05330  Allograft rejection
uar05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:uar00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    123788629 (IL12B)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    123788629 (IL12B)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    123788629 (IL12B)
   04622 RIG-I-like receptor signaling pathway
    123788629 (IL12B)
   04625 C-type lectin receptor signaling pathway
    123788629 (IL12B)
   04658 Th1 and Th2 cell differentiation
    123788629 (IL12B)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123788629 (IL12B)
   05205 Proteoglycans in cancer
    123788629 (IL12B)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    123788629 (IL12B)
   05164 Influenza A
    123788629 (IL12B)
   05162 Measles
    123788629 (IL12B)
   05168 Herpes simplex virus 1 infection
    123788629 (IL12B)
  09171 Infectious disease: bacterial
   05133 Pertussis
    123788629 (IL12B)
   05134 Legionellosis
    123788629 (IL12B)
   05152 Tuberculosis
    123788629 (IL12B)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    123788629 (IL12B)
   05145 Toxoplasmosis
    123788629 (IL12B)
   05140 Leishmaniasis
    123788629 (IL12B)
   05142 Chagas disease
    123788629 (IL12B)
   05143 African trypanosomiasis
    123788629 (IL12B)
  09163 Immune disease
   05321 Inflammatory bowel disease
    123788629 (IL12B)
   05330 Allograft rejection
    123788629 (IL12B)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123788629 (IL12B)
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    123788629 (IL12B)
   04936 Alcoholic liver disease
    123788629 (IL12B)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:uar04052]
    123788629 (IL12B)
   00536 Glycosaminoglycan binding proteins [BR:uar00536]
    123788629 (IL12B)
Cytokines and neuropeptides [BR:uar04052]
 Cytokines
  Interleukins
   123788629 (IL12B)
Glycosaminoglycan binding proteins [BR:uar00536]
 Heparan sulfate / Heparin
  Cytokines
   123788629 (IL12B)
SSDB
Motif
Pfam: IL12p40_C Ig_3 Ig_5 Ig_2 Ig_4 fn3 ig DBD_Tnp_Mut
Other DBs
NCBI-GeneID: 123788629
NCBI-ProteinID: XP_045648102
LinkDB
Position
Unknown
AA seq 329 aa
MQPQQLVVSWFSLVLLASPLMAVWELEKNVYVVELDWHPDAPGEVVVLTCHTPEEDDITW
TSDQSSEVLGSGKTLTVQVKEFGDAGRYTCHKGGKVLSDSLLLIHKKEDGIWSTDILKEQ
KESKNRIFLKCEAKNYSGRFTCWWLTAISTDLKFSVKSSRGFSDPQGVTCGAVTLSADRV
RVDNRDYKKYTVECQEGSACPTAEESLPIEVVVDAIHKLKYENYTRSFFIRDIIKPDPPM
NLQLKPLKNSRHVEVSWEYPDTWSTPHSYFSLTFCIQGQGKNHREKKERLCVDKTSAKVT
CPREAKIRVQARDRYYSSSWSDWAAVSCT
NT seq 990 nt   +upstreamnt  +downstreamnt
atgcagccgcagcagctggtcgtctcctggttctccctggttctgttggcatctcccctc
atggccgtatgggaactggagaaaaatgtttatgttgtagagttggactggcacccggac
gcccccggagaggtggtggtcctcacctgccatacccctgaagaggatgacatcacctgg
acctcagaccagagcagtgaagtcttaggctctggtaaaactctgaccgtccaagtcaaa
gaatttggagatgctggccggtatacctgtcataaaggaggcaaggttctgagcgattcg
ctcctgctgattcacaaaaaggaagatggaatctggtccactgatatcttaaaggaacag
aaagaatccaaaaataggatctttctaaaatgtgaggcaaagaattattctggacgtttc
acctgctggtggctgacggcaatcagtactgacttgaaattcagtgtcaaaagcagcaga
ggcttctctgacccccaaggcgtgacgtgtggagcagtgacactctcagcagacagggtc
agagtggacaacagggattataagaagtacacggtggagtgtcaggagggcagcgcctgc
cccacagccgaggagagcctacccatcgaggtcgtggtggacgctattcacaagctcaag
tatgaaaactacaccaggagcttcttcatcagggacatcatcaaaccggacccgcccatg
aacctgcagctgaagcccttaaaaaattctcggcatgtggaggtcagctgggaatacccc
gacacttggagcaccccgcattcctacttctccctgacattctgcatacagggccagggc
aagaaccatcgggaaaagaaagagagactctgcgtggacaagacctcggccaaggtcacg
tgccccagggaggccaagatccgcgtgcaagcccgagaccgctactacagctcatcctgg
agcgactgggcagctgtgtcctgcacttag

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