Ursus americanus (American black bear): 123789030
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Entry
123789030 CDS
T07931
Symbol
CFTR
Name
(RefSeq) cystic fibrosis transmembrane conductance regulator
KO
K05031
cystic fibrosis transmembrane conductance regulator [EC:
5.6.1.6
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar02010
ABC transporters
uar04024
cAMP signaling pathway
uar04152
AMPK signaling pathway
uar04530
Tight junction
uar04971
Gastric acid secretion
uar04972
Pancreatic secretion
uar04976
Bile secretion
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
123789030 (CFTR)
09132 Signal transduction
04024 cAMP signaling pathway
123789030 (CFTR)
04152 AMPK signaling pathway
123789030 (CFTR)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04530 Tight junction
123789030 (CFTR)
09150 Organismal Systems
09154 Digestive system
04971 Gastric acid secretion
123789030 (CFTR)
04972 Pancreatic secretion
123789030 (CFTR)
04976 Bile secretion
123789030 (CFTR)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
uar02000
]
123789030 (CFTR)
Enzymes [BR:
uar01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.1 Enzymes altering polypeptide conformation or assembly
5.6.1.6 channel-conductance-controlling ATPase
123789030 (CFTR)
Transporters [BR:
uar02000
]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC7 subgroup
123789030 (CFTR)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
CFTR_R
ABC_membrane
ABC_tran
SMC_N
AAA_21
AAA_29
T2SSE
DO-GTPase2
AAA_16
DUF87
RsgA_GTPase
MeaB
Zeta_toxin
MMR_HSR1
NTPase_1
AAA_30
NB-ARC
Intein_splicing
Motif
Other DBs
NCBI-GeneID:
123789030
NCBI-ProteinID:
XP_045648736
LinkDB
All DBs
Position
Unknown
AA seq
1476 aa
AA seq
DB search
SWRISLHSRISWTGPILSKGYRQRLELSDIYQIPSADSADNLSEKLEREWDRELASKKNP
KLINALRRCFFWRFMFYGILLYLGEVTKSVQPLLLGRIIASYDPDNKQERSIAIYLAIGL
CLLFVTRMLLLHPVIFGLHHIGMQMRIAMFSLIYKKTLKLSSRVLDKISIGQLISLLSNN
LNKFDEGLALAHFVWIVPLQVTLLMGLLWDLLQASAFCGLAFLIVLALFQAVLGRMMMKY
RDQRAGKINERLVITSEMIENIQSVKAYCWEEAMERMIENIRQTELKLTRKAAYVRYFNS
SAFFFSGFFVVFLSVLPYALIKTIILRKIFTTISFCIVLRMAVTRQFPWAVQTWYDSLGA
INKIQDFLQKQEYKTLEYNLTTTEVVMENVTAFWEEGFGELLEKAKQNSNDRKISNGDNS
LFFSNFSLLGAPVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGR
ISFCSQFSWIMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGIT
LSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTEKEIFESCVCKLMANKTRILVTSKM
EHLKKADKILILHEGSCYFYGTFSELQSLRPDFSSKLMGYDSFDQFSAERRNSIITETLR
RFSLEGDAAVSWNETKKQSFKQTGEFGEKRKNSILNPINSIRKFSIVQKTPLQMNGIEED
FNEPVERRLSLVAGSEQGEAILPISNMINSGPTFQRQRRQSVLNLMTCSPGSQGQSIHRR
TAASTRKMSLAPQANLTEMDIYSRRLSQDSGLEISEEINEEDLKECFFDDVESIPPVTTW
NTYLRYVTIHKNLVFVLIWCLVIFLAEVAVSLVVLWLLNKTASQEKGNSTQSINSSYAVI
FTNTSTYYVFYIYVGVADTLLALGFFRGLPLVHTLITVSKILHRKMLRAVLQAPMSTLNT
LKAGGILNRFTKDIAILDDLLPLTIFDFIQLLLIVIGAVVVVSALQPYIFLATVPVIAAF
ITLRAYFLHTSQQLKQLESEGRSPIFTHLVTSLKGLWTLRAFGRQPYFETLFHKALNLHT
ANWFLYLSTLRWFQMRMEIIFVIFFIAVTFISILTTGEGEGTIGIILTLAMNIMGTLQWA
VNSSIDVDSLMRSVSRVFKFIDMPTEESKPPTKSFKPSKDAQLSKVLITENHHVKEDDIW
PSGGQMTVKDLTAKYIDGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLNTE
GEIQIDGVSWDSVTLQEWRKAFGVIPQKVFIFSGTFRKNLDPYGQWNDQEIWKVADEVGL
KSVIEQFPGKLDFVLVDGGYVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPITYQII
RRTLKQAFADCTVILSEHRIEAMLECQRFLVIEESKVRQYDSIQKLLSEKSLFRQAISPS
DRLRFLPHRSSSKHRSRSKIAALKEETEEEVQETRL
NT seq
4431 nt
NT seq
+upstream
nt +downstream
nt
tcctggaggataagtctacattcccgcattagctggaccggaccaattttgtcaaaaggg
tatagacagcgcctggaattatcagacatataccaaatcccttctgctgattctgctgac
aatctgtctgaaaaattggaaagagaatgggacagagagctggcatcaaagaaaaacccc
aaactcattaatgcccttcggcgatgctttttctggagatttatgttctatggaatctta
ttatatttaggggaagtcaccaaatcagtccagcctctcttactgggaagaatcatagct
tcctacgatccggataacaagcaggaacgctccattgcgatttacctagccataggctta
tgccttctctttgtcacgaggatgcttctcctgcacccagtcatttttggccttcatcac
attggaatgcagatgagaatagctatgtttagcttgatttataagaagactttaaagctg
tcaagccgtgttctggataaaataagtattggacaacttattagtctcctttccaacaac
ctgaacaaatttgatgaaggacttgctttggcacattttgtgtggattgtacctttacaa
gtaacgcttctgatggggctactctgggatttgttacaagcctccgccttctgtggtctt
gctttcctcatagtcctcgccctttttcaagccgttttgggaagaatgatgatgaagtac
agagatcagagagctggaaagatcaatgaaagactcgtgatcacctcagaaatgattgaa
aatatccaatctgttaaggcatactgctgggaggaagcaatggaaagaatgattgaaaac
ataagacaaacagaactgaaactgacccggaaggcagcctatgtgagatacttcaatagc
tcagccttcttcttctcagggttctttgtggtgtttttatctgtgcttccctatgcactg
atcaaaacaatcatcctccgaaaaatattcacaaccatctcattctgcatcgttttgcgc
atggcggtcactcggcaattcccctgggctgtacaaacgtggtatgactctcttggagct
ataaacaaaatacaggatttcttacaaaagcaagagtataagacgttggaatataattta
acaactacagaagtagtgatggagaatgtaacagccttctgggaggagggatttggggaa
ttacttgagaaagcaaaacaaaacagtaatgacagaaaaatttccaatggtgataacagc
ctcttcttcagcaacttctcacttctgggtgctcctgtcctgaaagacatcaatttcaag
atagaaagaggacagttgttggcggttgctggatctactggagcaggcaagacttcactt
ctaatgatgattatgggagaactggagccttcagagggtaagattaagcacagtggaaga
atttcattctgctctcagttttcctggatcatgcctggcaccattaaagaaaacatcatc
tttggtgtttcctatgatgagtacagatataggagtgtcatcaaagcatgtcagctagag
gaggacatttccaagtttgcagagaaggacaatattgttcttggagaaggcggaatcaca
ctgagtggagggcagcgagcaagaatttccttagcaagagcagtatataaagatgctgat
ttatacctattagactctccttttggatatctggatgttttaacagaaaaagaaatattt
gaaagctgtgtctgtaaattgatggctaacaaaactaggattttggtcacttctaaaatg
gaacatttaaagaaagctgacaaaatattaattttacatgaaggtagctgctatttttat
gggacattttctgaattacaaagtctacggcccgacttcagctcaaagctcatgggatat
gattcttttgaccagtttagtgcagaaagaagaaattcaatcataactgagactttacgg
cgtttctcattagaaggagatgcggctgtttcctggaatgaaacaaaaaagcaatctttt
aaacagactggagagtttggtgaaaaaaggaagaactctattcttaatccaatcaactct
atcagaaaattttcaattgtacagaagactccattacaaatgaatggcattgaagaagat
ttcaatgaacccgtagagagaaggctgtccttagttgcgggtagtgagcaaggagaggcc
atcctgcctataagcaacatgatcaacagtggccccacgtttcagagacaacgaaggcag
tctgttctgaatctgatgacgtgctccccagggagccagggtcaaagtattcaccgaagg
acagctgcatccacacgaaaaatgtctctggccccgcaggcaaacttaactgaaatggat
atatattcaagacggttatctcaagatagtggcttggaaataagtgaagaaattaacgaa
gaagacttaaaggagtgcttttttgacgacgttgagagcataccaccggtgactacatgg
aacacataccttcgatatgttactatccacaagaacttagtctttgtgctaatttggtgc
ttagttatttttctggctgaggtggctgtttctttggttgtgttgtggctgcttaataaa
acagcttctcaagagaaagggaatagtactcagagcataaatagcagttatgcagtgatc
ttcaccaataccagcacatattatgttttttatatttatgtgggagtagctgacacgttg
cttgctctgggattcttcagaggtttaccactggtgcatactctaatcacagtgtcgaaa
attttacaccgcaaaatgttacgtgctgttcttcaagcacctatgtcaaccctcaacacg
ttgaaagcaggtgggattcttaatagattcaccaaagatatagcaattttggatgatctt
ctgccccttaccatatttgacttcatccagttgttactaattgtgattggagctgtggta
gtagtctcggctttgcaaccctacatcttcctagcaacagtgcccgtgatagcagctttc
attacactgagggcctacttcctccacacctcacagcaactcaaacagctggaatctgaa
ggcaggagtccaattttcactcatcttgttacaagcttaaaaggactatggacacttcgg
gcctttggacgtcagccttactttgaaactttgtttcacaaggctctgaacttacatacc
gccaactggttcttgtacctctccacactgcgctggttccaaatgagaatggaaattatt
tttgtcatattcttcattgctgttaccttcatttccattttaacaacaggcgaaggagaa
ggaacaattggtattattctaacattagccatgaatatcatgggtacattgcaatgggct
gtaaactccagcatagatgtggatagcttgatgcgatctgtgagccgagtcttcaagttt
attgacatgccaacagaagaaagtaaaccacctaccaagtcattcaaaccatccaaggat
gcccagctctcaaaagttttgattactgagaatcatcatgtgaaggaagatgacatctgg
ccctcagggggccaaatgactgtcaaagacctcacagccaagtatatagatggtgggaat
gccatattagagaacatttccttctcaataagtcctggccagagggtgggcctcttggga
agaaccggatcagggaagagtactttgttatcggcttttttgagactgctgaacactgag
ggagaaatccaaatagatggtgtgtcttgggattcagtaactttgcaagagtggaggaaa
gcctttggagtgatcccacagaaagtatttattttctctggaacatttagaaaaaacttg
gatccctatggacagtggaatgatcaagaaatatggaaagttgcagatgaggttggactc
aaatctgtgatagagcagtttcctgggaagctcgattttgtcctggtggatgggggttac
gtcctaagccacggccacaagcagttgatgtgcttggccagatctgttctcagtaaagca
aagatcttgctgcttgatgaacccagtgctcatttggatccaataacataccaaatcatt
cgaagaaccctaaaacaagcatttgcagattgcacagtaatcctctctgaacacaggata
gaagctatgttggaatgtcagcgatttttggtcatagaggagagcaaggtgcggcagtac
gattccatccagaagctgctgagcgagaagagcctcttccggcaggccatcagcccctcg
gaccggctgcggttcctcccacaccggagctccagcaagcacaggtctcgatccaagatc
gctgctctgaaggaggagacagaggaagaggtgcaagaaacaaggctctag
DBGET
integrated database retrieval system
