KEGG   Ursus americanus (American black bear): 123789330
Entry
123789330         CDS       T07931                                 
Symbol
ABCB1
Name
(RefSeq) ATP-dependent translocase ABCB1
  KO
K05658  ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2]
Organism
uar  Ursus americanus (American black bear)
Pathway
uar02010  ABC transporters
uar04976  Bile secretion
uar05206  MicroRNAs in cancer
uar05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:uar00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    123789330 (ABCB1)
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    123789330 (ABCB1)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    123789330 (ABCB1)
  09162 Cancer: specific types
   05226 Gastric cancer
    123789330 (ABCB1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:uar02000]
    123789330 (ABCB1)
   04147 Exosome [BR:uar04147]
    123789330 (ABCB1)
   04090 CD molecules [BR:uar04090]
    123789330 (ABCB1)
Enzymes [BR:uar01000]
 7. Translocases
  7.6  Catalysing the translocation of other compounds
   7.6.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.6.2.2  ABC-type xenobiotic transporter
     123789330 (ABCB1)
Transporters [BR:uar02000]
 ABC transporters, eukaryotic type
  ABCB (MDR/TAP) subfamily
   ABCB1, 4, 5 subgroups
    123789330 (ABCB1)
Exosome [BR:uar04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   123789330 (ABCB1)
CD molecules [BR:uar04090]
 Proteins
  123789330 (ABCB1)
SSDB
Motif
Pfam: ABC_membrane ABC_tran SMC_N ABC_ATPase Rad17 AAA_22 AAA_16 RsgA_GTPase Zeta_toxin AAA_5 AAA_29 G-alpha AAA_7 AAA_30 DUF815 PRK APS_kinase nSTAND3 DUF2207_C NTPase_1 NEMP
Other DBs
NCBI-GeneID: 123789330
NCBI-ProteinID: XP_045649295
LinkDB
Position
Unknown
AA seq 1280 aa
MDLEGGHNGRAEKNFLKMGKKSKKDEKKEKKPTVSTFAMFRYSNWLDRFYMLVGTMAAII
HGAALPLMMLVFGDMTDSFANAGIARNTSFINITNGSITNNATFIHLLEEEMTTYAYYYS
GIGAGVLVAAYIQVSFWCLAAGRQILKIRKQFFHAIMRQEIGWFDVHDVGELNTRLTDDV
SKINEGIGDKIGMFFQSIATFFIGFIVGFTRGWKLTLVILAISPVLGLSAAIWAKILSSF
TDKELLAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNKNLEEAKRIGIKKAITANISI
GAAFLLIYASYALAFWYGTSLVLSNEYSIGQVLTVFFSVLIGAFSIGQASPSIEAFANAR
GAAYEIFKIIDNKPSIDSYSKNGHKPDNIKGNLEFKNVHFSYPSRKEVKILKGLSLKVES
GQTVALVGNSGCGKSTTVQLLQRLYDPTDGMVCIDGQDIRTINVRHLREITGVVSQEPVL
FATTIAENIRYGRENVTMEEIEKAVKEANAYDFIMKLPNKFDTLVGERGAQLSGGQKQRI
AIARALVRNPKILLLDEATSALDTESEAVVQVALDKARKGRTTIVIAHRLSTVRNADVIA
GFDDGVIVEKGSHDELMREKGIYFKLVTMQTSGNEIELENGTGESKSEIDALEMSPKDSG
SSLIRRRSTRKSIHAPQGQDRKLGTKEDLDENVPPVSFWRILKLNITEWPYFVIGIFCAI
INGGLQPAFSVIFSRIIGIFTRDGDPETKRQNSNMFSLLFLVLGIISFITFFLQGFTFGK
AGEILTKRLRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGSRLAVITQN
IANLGTGIIISLIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGAGKIATE
AIENFRTVVSLTREQKFEYMYAQSLQVPYRNSLRKAHIFGISFSITQAMMYFSYAGCFRF
GAYLVANRFMNFQDVLLVFSAIVFGAMAVGQVSSFAPDYAKAKVSAAHIIMIIEKTPLID
SYSTGGLQPNTLEGNVTFNEVVFNYPTRPDISVLQGLSLEVKKGQTLALVGSSGCGKSTV
VQLLERFYDPLAGTVLIDGVEIKHLNVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSRV
VSQEEIVRAAKEANIHPFIETLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLL
DEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADFIVVFQNGKVKEHGTHQQ
LLAQKGIYFSMVSVQAGAKR
NT seq 3843 nt   +upstreamnt  +downstreamnt
atggatcttgaaggaggccataatggaagagcagagaagaacttcttgaaaatgggcaaa
aaaagtaaaaaagatgagaagaaagaaaagaaaccaactgtcagcacatttgcaatgttt
cgctactcaaattggcttgataggttctatatgttggtggggacaatggctgccatcatc
catggagctgcactccccctcatgatgctggtttttggagacatgacagatagctttgca
aatgcaggaattgcaagaaacacatcttttataaacataactaatggaagtattacgaac
aatgcaactttcatccaccttctggaggaggaaatgaccacgtatgcctattattacagt
gggattggggctggagtgctagttgccgcttacatccaggtttccttctggtgcctggca
gctggaagacagatactcaaaattaggaaacagttttttcacgctattatgagacaggag
atcggctggtttgacgtgcatgatgtgggagagcttaacacccggctcacggatgatgtc
tccaaaatcaatgaaggaattggtgacaaaattggaatgttctttcagtcaatagcaaca
tttttcatcggttttatagtgggatttacacgtggttggaagctaacccttgtgattttg
gccatcagtcctgttcttggactgtcagctgctatctgggcaaagatactatcttcattt
actgataaagaactcttggcatatgcaaaagctggagcagtagctgaagaggtcttagca
gcaatcagaactgtgattgcctttggaggacaaaagaaagaacttgaaaggtataacaaa
aatttagaagaagctaaaagaattgggataaagaaagctatcacggccaacatttctatt
ggtgctgctttcctgttgatctatgcatcatatgctctggcattctggtatgggacctcc
ttggtcctctccaatgaatattctattggacaagtactcactgtcttcttttctgtatta
attggggcttttagtatcggacaggcatctccaagcattgaagcatttgcaaacgcaaga
ggagcagcttatgaaatcttcaagataattgataacaaaccaagcattgacagctattcg
aagaacggacataaaccagataatattaagggaaatttggaattcaaaaatgttcacttc
agttacccatcgcgaaaagaagttaagatcttgaagggcctcagcctgaaggttgagagc
gggcagacggtggcgctggtcgggaatagcggctgcgggaagagcacgacggtgcagctg
ttgcagaggctctatgaccccacggacggcatggtctgtattgatggacaggacattagg
accataaacgtcaggcaccttcgggaaattactggcgtggtgagtcaggaacctgtgttg
tttgccaccaccatagctgaaaacattcgctatggccgcgaaaatgtcaccatggaagag
atcgagaaagccgtcaaggaagccaacgcctatgactttatcatgaaactccctaacaaa
tttgacaccctggttggagagaggggcgcccagctgagcggcggacagaagcaaagaatc
gccattgctcgggccctggttcgcaaccccaagatcctcctgctggacgaggccacgtca
gccctggacactgaaagtgaagcagtagttcaggtggccctggataaggccaggaaaggc
cggaccaccattgtgatagctcatcgtttgtctacagttcgtaatgctgatgtcatcgct
ggctttgatgatggagtcattgtggagaaaggaagtcatgatgaactcatgagagagaaa
ggcatttacttcaagcttgtcacaatgcagacaagtggaaatgaaattgaattagaaaat
ggaactggtgaatccaaaagtgaaattgatgccttggaaatgtctccaaaggattcagga
tccagtttaataagaagaagatcaacccgcaagagtatacatgccccacaaggccaggac
agaaagcttggtacaaaagaggacttggatgaaaatgtacctccagtttccttctggagg
attctgaagctgaatataactgaatggccttatttcgtgattggtatattttgtgctatt
ataaatggaggcctgcaaccagcattttcagtcatattttcaaggattatagggattttt
accagagatggggatcctgaaacaaaacgacagaatagtaatatgttttctttattgttt
ctagtccttggaattatttcttttattacatttttcctccagggcttcacgtttggcaaa
gccggggagatcctcaccaagcgcctccgatacatggttttcaggtcgatgctgagacag
gatgtgagctggtttgatgaccctaaaaataccaccggagcattgacaaccaggcttgcc
aatgatgctgctcaagttaaaggggctattggttccaggcttgctgtaattacccagaat
atagcaaatcttgggacaggcattattatatccttaatctatggctggcaattaacactt
ttactcttagcaattgtacccatcattgcaatagcgggagttgttgaaatgaaaatgttg
tctggacaagcactgaaagataagaaagaactggaaggtgctgggaagattgctactgaa
gcgatcgaaaacttccgaactgttgtttctttgacccgggagcagaagtttgaatacatg
tatgcacagagtttgcaagtaccatacagaaactctttgaggaaagcacacatctttggg
atctcattttccatcacccaggcaatgatgtatttttcctatgctggctgtttccgattt
ggtgcctacctggtggcaaacaggttcatgaactttcaggatgttcttttggtattctca
gctatcgtctttggtgccatggcggtggggcaggtcagttcatttgctcctgactatgcc
aaagccaaagtatcagcagcccacatcatcatgatcattgaaaaaacccctctgattgac
agctacagcacaggaggcctccagccgaatacactggaaggaaatgtgacatttaatgaa
gtcgtgttcaactatcccactcgaccagacatctccgtgcttcaggggctgagccttgag
gtgaagaagggccagacgctggcactggtgggcagcagcggctgtgggaagagcacggtg
gtccagctccttgagcggttctatgaccccttggctggaacagtgctaattgatggcgta
gagataaagcacctgaatgtccaatggctccgagcccacctgggcattgtgtcccaggag
cccatcctgttcgactgcagcattgctgagaacattgcttatggagacaacagccgggtc
gtgtcccaggaagagatcgtgcgggcggccaaagaggccaacatacaccccttcatcgag
acactccctgataaatataacaccagagtaggagacaaaggaacccagctctctgggggc
cagaagcagcgcattgccatagctcgcgcccttgttcgacagcctcatattttgcttttg
gatgaagctacatcagctctggatacagagagtgaaaaggttgtccaagaagctctggac
aaagccagagagggccgcacctgcatcgtgatcgctcaccgcctgtccaccatccagaac
gcagacttcatagtggtgtttcagaacggcaaggtcaaggagcatggcacccatcaacag
ttgctggctcagaaaggcatctatttttccatggtcagtgtccaggctggagcaaagcgc
tag

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