Ursus americanus (American black bear): 123791546
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Entry
123791546 CDS
T07931
Symbol
PDE8B
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar00230
Purine metabolism
uar01100
Metabolic pathways
uar04927
Cortisol synthesis and secretion
uar04934
Cushing syndrome
uar05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
123791546 (PDE8B)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
123791546 (PDE8B)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
123791546 (PDE8B)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
123791546 (PDE8B)
Enzymes [BR:
uar01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
123791546 (PDE8B)
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PDE8
PAS_9
PAS
PAS_3
PAS_4
PAS_8
DUF3757
DUF4194
DHH
Motif
Other DBs
NCBI-GeneID:
123791546
NCBI-ProteinID:
XP_045652376
LinkDB
All DBs
Position
Unknown
AA seq
890 aa
AA seq
DB search
MGCAPSIHVSQSGVIYCRDSDESNSPRQTTSVSQGPAAPLHGLFVQTDAADVIPPSRASG
PPGAARVRRARAELGSGGSSSSSSAGSAAPAATTCRGRRRHCCSSAEAETQTSYTSVKQV
SSAEVRIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNIARTPESALECFLDK
HHEIIVIDHRQTRNFDAEAVCRSIRATNPSEHTVILAVVSQALGDHEEASVLPLLHAGFN
RRFMENSNIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVN
PAFERMMGYHKGELLGKELAELPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSI
QQHVKITPVIGQGGKIRHFVSLKKLCCTTDNNKQLHKLHRDSGDNSQTESHSLRYKNRRK
ESIDVKSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEAL
DRVLEILRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVHQSHSHLA
MPITINDVPPCIAQLLDNEESWEFNIFELEAVTHKRPLVYLGLKVFSRFGVCEFLHCSET
TLRAWLQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVH
DVDHPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDSKCNIFKNIDRNHYRT
LRQAIIDMVLATEMTKHFEHVNKFVNSINKPMAAESEGSDCECNPTGKNFPENQILIKRM
MIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQIS
FIDYFITDMFDAWDAFAHLPALMQHLADNYKHWKTLDDLKCKSLRLPSDS
NT seq
2673 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcgcccccagcatccacgtctcgcagagcggcgtgatctactgccgggactcg
gacgagtccaactcgccccgccagaccaccagtgtgtcgcagggccccgcggcccccctg
cacggcctcttcgtccagaccgacgccgccgacgttattcccccaagccgcgcgtcggga
cccccgggagccgcccgcgtccgcagggcccgcgccgagctgggcagcggcggcagcagc
agcagcagcagcgcgggctccgcagcccccgccgcgaccacctgcaggggccggaggcgc
cactgctgcagcagcgcggaggccgagacccagaccagctacaccagcgtcaagcaggtc
tcatctgcggaggtgcgcattgggcccatgagactgacgcaggatcctattcaggttttg
ctgatctttgcaaaggaagatagtcagagtgatggattctggtgggcctgtgacagagct
ggttatagatgcaatattgctcggactccagagtcagcccttgaatgctttctagataaa
catcatgaaattatcgtaatagatcacagacagactcgaaactttgatgcagaagcggtg
tgcaggtcgatccgggccacaaatccttccgagcacacggtgatccttgcggtggtttca
caagcattgggtgaccatgaagaggcctcagtcctccctctcctgcatgcaggcttcaac
aggagatttatggagaatagcaacataattgcttgctataatgaactgattcaaatagaa
cacggggaagttcgctcacagttcaaactacgggcctgtaattcggtgtttacggcatta
gaccactgtcatgaagccatagaaattacaagcgatgaccatgtgattcagtacgtcaac
ccagcctttgaaaggatgatgggctaccacaaaggcgagctgctggggaaagagctcgct
gagctgcccaaaagtgataagaaccgggccgaccttctcgacaccatcaacacatgcatc
aagaagggcaaggagtggcagggggtttactatgccagacggaaatccggggacagcatc
caacagcacgtgaagatcaccccggtgattggccaaggagggaaaattaggcattttgtc
tccctcaagaaactgtgttgtaccactgacaataataagcagcttcacaagcttcatcgt
gattcaggagacaattctcagacagagtctcattcactcagatacaagaacagaaggaaa
gagtccattgatgtgaaatcgatatcctctcgaggcagtgatgcaccaagcctacagaac
cgtcgctatccatccatggcaaggatccattccatgaccatcgaggctcccatcacaaag
gttataaatataatcaatgcagcccaagagaacagccccgtcacagtagcagaagccttg
gacagagttttagaaattttacggaccacagaactgtattcccctcagctgggtaccaaa
gatgaagatccccacaccagcgatcttgttggaggcctgatgactgatggcttgagaagg
ttgtcaggaaacgagtatgtattcactaagaatgtgcaccagagtcacagtcaccttgcg
atgccaataaccatcaacgatgtccccccttgtatcgctcaattacttgataatgaggaa
agttgggagttcaacatctttgaattggaagctgttacacataaaaggccattggtttac
ctgggcttaaaggtattttctcggtttggagtatgtgaatttttacactgctctgaaact
actcttcgggcctggctccaagtgattgaagccaactaccactcctccaatgcctaccat
aactccacccatgccgccgatgtcctgcacgccactgctttcttccttggaaaggaacga
gtgaagggaagcctcgatcagctggatgaggtggcagcgctgattgccgccacagtccac
gatgtggatcacccggggaggaccaactcgttcctgtgcaacgcaggcagtgaactggct
gtgctctataacgacactgctgtcttggagagtcaccacaccgccctggctttccagctc
acagtcaaggacagcaaatgcaacattttcaagaatatcgacaggaaccattatcggaca
ctgcgccaggctattattgacatggtgttagcaacggagatgaccaaacactttgaacat
gtgaacaaatttgtgaacagcatcaataagccaatggcagctgagagtgagggcagcgac
tgtgaatgcaaccctactgggaagaactttccggaaaaccaaatcctgatcaaacgtatg
atgataaagtgtgctgatgtagccaacccatgtcgccccctggacctgtgcatcgaatgg
gctgggaggatctcggaggagtactttgcacagactgatgaagagaagagacaggggctc
cctgtggtgatgccagtgtttgaccggaatacctgcagcatccccaaatcccaaatctcc
ttcattgactacttcataacagacatgtttgatgcttgggatgcctttgcccatctgcca
gccctgatgcaacatttggctgataactacaaacactggaagacattagatgacctcaag
tgcaaaagtctgaggcttccatctgacagctaa
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