Ursus americanus (American black bear): 123791665
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Entry
123791665 CDS
T07931
Symbol
PDE3B
Name
(RefSeq) cGMP-inhibited 3',5'-cyclic phosphodiesterase B isoform X1
KO
K13296
cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:
3.1.4.17
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar00230
Purine metabolism
uar01100
Metabolic pathways
uar04022
cGMP-PKG signaling pathway
uar04024
cAMP signaling pathway
uar04371
Apelin signaling pathway
uar04910
Insulin signaling pathway
uar04914
Progesterone-mediated oocyte maturation
uar04922
Glucagon signaling pathway
uar04923
Regulation of lipolysis in adipocytes
uar04924
Renin secretion
uar05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
123791665 (PDE3B)
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
123791665 (PDE3B)
04024 cAMP signaling pathway
123791665 (PDE3B)
04022 cGMP-PKG signaling pathway
123791665 (PDE3B)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
123791665 (PDE3B)
04922 Glucagon signaling pathway
123791665 (PDE3B)
04923 Regulation of lipolysis in adipocytes
123791665 (PDE3B)
04914 Progesterone-mediated oocyte maturation
123791665 (PDE3B)
04924 Renin secretion
123791665 (PDE3B)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
123791665 (PDE3B)
Enzymes [BR:
uar01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
123791665 (PDE3B)
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SSDB
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Paralog
GFIT
Motif
Pfam:
PDEase_I
DUF1129
Motif
Other DBs
NCBI-GeneID:
123791665
NCBI-ProteinID:
XP_045652500
LinkDB
All DBs
Position
Unknown
AA seq
1124 aa
AA seq
DB search
MRRDERDAKAMRCPQPPDGAGSPPESLRNGYVKSCVSPLRQDPPRGFFFHLCRFCNVELL
LPPPASPQQPRRGSPSARARLSLGALAAFVLALLLSSGPGSWAVGAARLRTLLSVCSHSL
SPLFSIACAFFFLTCFLTRSKRGPGPGRSGGGSWWLLALPACCYLGDFLVWQAWAWAWGP
GDAGAPATAPLTPPAVAGRLFSVLSCVGLLTLAHPARLRHSILVLLFSSFVWWVSFTGLG
SLPAALRPLLSCLVGDAGCLLALGLDHFFQIREAPHHPRLASASEDKVPVIRPRRRSSCV
SFGETSAGYSGSCKMLRRPSLPCISREQMILWDWDLKQWYKPHYQNSGGGSGVDLSVLNE
ARNMVSDLLVDPTLPPQVISSLRSISSLMGAFSGSCRPKINPLTPFPGFYPCSEIEDPTE
KGDRKLHKQGLNSRNSLPTPQLRRSSATSGLPPVEQASSRWERSNGKRPHQEFGISSQGS
YLNGPFSSNLLTIPKQRSSSVSLTHHIGLRRAGAFPSLSPVNSPSHGPVSAGSLTNRSPI
EFPDTANFLTKPSVILHRSLGSAPNSPDIYQQLRNSDSSLCNSCGHQILKYVSTSESESG
TDCHNAKSGDEDSAVPSKPSFNCTEVQQEVETENRDCRKLSVEGDNHLTEEAQHEQQPNV
EQGASLDLILIEDYDSLIEKMSNWNFQIFEVVEKMGEKSGRILSQVMYTLFQDTGLLEIF
KIPTLQFMNYFRALENGYRDIPYHNRIHATDVLHAVWYLTTRPVPGLQQIHGDRAAGSEA
DADGRMNPGPIAYLSSRSCSIPDASYGCLSSNIPALELMALYVAAAMHDYDHPGRTNAFL
VATNAPQAVLYNDRSVLENHHAASAWNLYLSRPEYNFLLNLDHVEFKRFRFLVIEAILAT
DLKKHFDFLAEFNAKANDVNSNGIEWSNENDRLLVCQVCIKLADINGPAKVRDLHLKWTE
GIVNEFYEQGDEEANLGLPISPFMDRSSPQLAKLQESFITHIVGPLCNSYDAAGLLPGQW
IEAEDDEDTESCSGEDGDELDTDDEEIEDNLNPKPQRRKGRRRIFCQLMQHLTENHKTWK
EIIEEEEKCKADGSKLQVENPSLPQADDIQVIEEADEEEERQFE
NT seq
3375 nt
NT seq
+upstream
nt +downstream
nt
atgaggagggacgagcgagacgccaaagccatgcggtgcccgcagccgccggacggagcc
ggctcgccccccgagagtctgaggaacggctacgtgaagagctgcgtgagccctttgcgg
caggaccctccgcgcggcttcttcttccacctctgccgcttctgcaacgtggagctgctg
ctgccgccgccggcctccccccagcagccgcgccgcggctccccctccgcccgggcgcgc
ctctcgctgggcgccctggccgcctttgtcctcgccctgctgctcagctcggggcccggg
agctgggctgtcggggccgcccggctgcggaccctgctgagcgtgtgctcgcacagcctc
agccccctcttcagcatcgcctgtgccttcttcttcctcacctgcttcctgacccggagc
aagcggggccccgggccgggccggagcggcggaggctcctggtggctgctggcgctgcca
gcctgctgttacctgggggacttcttggtgtggcaggcgtgggcttgggcttgggggccc
ggagacgcgggggcccccgccacggccccgctcacgcccccggcggtggcgggcaggttg
ttctcggtactgagctgcgtgggcttgctgacgctcgcgcacccggcgaggctccggcac
agcatcctggtgctgctcttctccagcttcgtctggtgggtctccttcaccggcctcggg
tcgctgcccgcagccctcaggccgctgctctcctgcctggtcggggacgccggctgcctg
ctagcgctgggcttggatcacttctttcagatcagggaagcccctcatcatcctcgcttg
gccagtgcctccgaggacaaagtgcctgtgatcagaccccgcaggaggtccagctgcgtg
tcgttcggagaaacttcggcgggttactccggcagctgcaagatgttgaggagaccttcg
ttgccttgcatttcccgagaacagatgattctttgggattgggacttaaagcaatggtat
aaacctcattatcagaattctggaggtggaagtggagttgatctttcagtgctaaatgag
gctcgcaatatggtgtcagatcttctggtcgatccgacccttcccccacaagtcatttcc
tcccttcggagtatcagtagcttgatgggtgctttctcaggttcctgtaggccaaagatt
aatcctctgacaccatttcctggattttacccctgctcagaaatagaggacccaactgag
aaaggagatcgaaaacttcacaagcagggactaaacagcaggaacagtttaccaaccccg
cagctgaggaggagttccgccacctcaggtctgcctcccgttgaacaggcttcttcaagg
tgggaacgcagtaatggcaagaggccacaccaagagtttggcatttcaagtcaaggatcc
tatctaaatgggccttttagttcaaatctactgacaatcccgaagcaaaggtcatcttct
gtatccctaactcaccatataggtctaagaagagctggtgctttccccagcctgagtcct
gtgaattctcccagccatggaccagtgtctgctggctctctaactaatcgatcacccata
gaatttcctgacactgccaattttcttactaagccaagtgttattttacacagatctctg
ggcagtgcacccaattcaccagatatttatcagcaacttagaaattctgatagcagtttg
tgtaacagctgtggacatcaaatattgaaatatgtgtcaacgtccgaatcggagtctggg
acagactgccacaatgcaaagtcaggtgatgaagacagcgctgttccctcaaaaccgtca
ttcaactgtacagaagtgcaacaagaagtggaaaccgagaacagagactgcaggaaatta
tctgtggaaggtgataatcacctaacagaagaggcccagcatgaacagcagccaaatgtg
gaacagggagcttcactggacctgattttgatagaagattatgattccctgatagagaag
atgagcaactggaattttcaaatatttgaagttgtagaaaaaatgggagagaaatcagga
aggattcttagccaggttatgtataccttatttcaagacactggcctgttggaaatattt
aaaatccccactctgcagttcatgaactattttcgtgcattggaaaatggctatcgagac
attccttatcacaatcgcatacacgccacggatgtcctacatgcagtttggtatctgacg
acgcggccagttcctggtctacagcagatccacggtgaccgtgcagcaggaagcgaagca
gacgctgatggtagaatgaaccccgggccaattgcttacctctcttcgagaagctgctcg
attccagatgccagctatggttgcctgtcgtccaacattcccgcgctggaactgatggct
ctctatgtggcggctgccatgcatgattacgatcacccagggcggacaaacgcgtttctg
gtggctacaaatgccccgcaggcagttttgtacaacgacagatctgttctagaaaatcat
catgcggcatcagcttggaatctgtatctctctcgcccagaatacaacttccttcttaat
cttgatcatgtggaattcaagcgctttcgttttttagtcattgaagcaatccttgccaca
gatcttaaaaagcattttgatttccttgctgaattcaacgccaaggccaacgatgtaaat
agtaatggtatagaatggagcaatgagaacgatcgcctcttagtatgccaagtgtgcatt
aaactggcagacatcaatggcccagcgaaagttcgggacttgcatttgaaatggacagaa
ggcattgtcaatgaattttatgagcagggagatgaagaagcaaacctcggtttacccatc
agtcccttcatggatcgttcttcgcctcaactagcaaaactccaagaatctttcatcacc
cacatcgtggggcccctgtgtaattcctacgatgctgcgggcttgctgccgggtcagtgg
atagaagccgaagacgatgaggacacggagagctgttccggtgaagatggtgacgaatta
gataccgatgatgaagaaatagaagacaatctaaatcctaaaccacagaggaggaaaggc
agacggcggatattttgtcagctaatgcagcacctcacggaaaaccacaagacatggaag
gagatcatagaggaagaagagaaatgtaaagctgatgggagtaaactgcaggtggaaaat
ccttccttacctcaagcagatgacattcaggtcatcgaagaagcagatgaagaggaggag
agacagtttgaatag
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