Ursus americanus (American black bear): 123792127 Help Entry 123792127         CDS       T07931                                  Symbol DNAH2 Name (RefSeq) dynein axonemal heavy chain 2   KO K10408   dynein axonemal heavy chain Organism uar  Ursus americanus (American black bear) Pathway uar04814   Motor proteins uar05014   Amyotrophic lateral sclerosis uar05016   Huntington disease uar05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:uar00001]  09140 Cellular Processes   09142 Cell motility    04814 Motor proteins     123792127 (DNAH2)  09160 Human Diseases   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     123792127 (DNAH2)    05016 Huntington disease     123792127 (DNAH2)    05022 Pathways of neurodegeneration - multiple diseases     123792127 (DNAH2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    03037 Cilium and associated proteins [BR:uar03037]     123792127 (DNAH2)    04812 Cytoskeleton proteins [BR:uar04812]     123792127 (DNAH2) Cilium and associated proteins [BR:uar03037]  Motile cilia and associated proteins   Dynein arm    123792127 (DNAH2) Cytoskeleton proteins [BR:uar04812]  Eukaryotic cytoskeleton proteins   Microtubules    Tubulin-binding proteins     Dyneins      123792127 (DNAH2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AAA_6 DHC_N2 DHC_N1 Dynein_C AAA_8 AAA_9 AAA_7 AAA_lid_11 MT Dynein_heavy AAA_5 Dynein_AAA_lid AAA_lid_1 AAA AAA_22 AAA_16 Mg_chelatase Sigma54_activat nSTAND3 NB-ARC FtsK_SpoIIIE Sigma54_activ_2 DUF3452 IL2 DUF815 AAA_2 Trypan_PARP ATP_bind_1 Guanylate_kin Motif Other DBs NCBI-GeneID:  123792127 NCBI-ProteinID:  XP_045653291 LinkDB All DBs Position Unknown AA seq 4430 aa AA seqDB search MSSRAEKKRKVSAQGSASRGGTRRRAAQAAALASQAAETTLASGEPELEPEPEPLKEELE PTLEEPEVEKEEFPEPEVDVKPLFLSQAVLTGLADAVWTAEHDAILEHFAQDPSELILTI FIDPYMGLKLDLGMPVQTQNQIVYFIRCAPVPITPENFEATVQFGTVRGSYIPALLQLLS GVFAPQIFANTIWPESIRNHFASHLHRFLACLTDTRYKLEGHTVLYIPAEAMNMAPEVVV KDKELVQRLETSMIHWTRQIKEVLSAQESVETGENLGPLEEIEFWRNRCMDLSGISMQLV KQGVKHIESILRLAKSSYLAPFMKLAQQIQDGSRQAQSNLTFLSILKEPYQELAYMRPKD ISSKLPKLISLIRIIWVNSPHYNTRERLTSLFRKVCDCQYHFARWEDGKQAPLPCFFGAQ GPQITRNLLEIEDIFHKNLHMLRAVRGGILDVKNTSWHEDYNRFRTGVKDLEVMTQNLIT SAFELVRDVEQGVLLLDTFHRLATREAIKRTYDKKAVDLYMLFNTELALVNRELNKKWLF LEPYMAQYSGQAHWMRILRHRIDRVMNCLSSAHFLPHIGTGEESVHTYQQMVQAIDELVR KTFQDWTLTLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFVEIDYWERLLFETPH YVMNVAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRFLDKKIHPGLKKLH WALKGASAFFITECRIHASKVQTIANEFKASTLTIGWRAQEISETLLVRISGKRVYRDLE FEEDQREHRAAVQQKLMSLHQDVVAIMTNSYEVFKNDGPEIQQQWMLYTIRLDRMMEDAL RLNVKWSLLELSKAINGDGKTTPNPLFRVLVILQNDMQGVAQVEFSPTLQTLAGVVNDIG HHLFSTISVFRHLPEILIRRKFHRDPIHIIVERDEDIKKIQAQISSGMTNNASQLQNYLK TWDLYREIWEINKDSFIRRYQRLNPPVSSFDADIARYTEVANNVQKEETVLNIQFVLLDC SHLKFSLVQHCSEWQNKFTTLLKEMAARRLLELHTYLRDNGEKISRPPQTLEELGVSLQL METLQHDLPNLETQIPPIHEQFTILEKYEVPVQENVLEMLDSLNGEWVTFQQILLDSEQM LKKHKEKFKTGLIHSADDFKKKAHNLLEDFESRGPFTSNVGHQAALEQIAQVRAMLNAMQ EEENSLRSNLGIFKIEQPASKDLQNLEKELDALQQVWEITRDWEENWNQWKTGRFLTLQT EAMETMAHGLFRRLTRLSKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWD QVRDEIQREFDPESESFTLEQIVDLGMDQHVEKIGEISASATKELAIELALQNIAKTWSV IQLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKEVDHWERCLSLIL EVVEMVLTVQRQWMYLENIFLGEDIRKQLPSESALFDQVNNNWKSIMDRLSKDSNALEST HHPGLLDTLIEMNTVLEDIQKSLDMYLETKRHVFPRFYFLSNDDLLEILGQSRNPEAVQP HLKKCFDNIKLLRMQKVGGPGSKWEAVGMFSGDGEYVDFLHTVLLEGPVESWLGDVERTM RVTLRDLLRNCRLALKKFLNKRDKWVKEWAGQMVIAASQIQWTADVTKCLLTAKERGDKK ILKVLKKKQVSVLNKYSEAIRGNLTKIMRLKIVALVTIEVHARDVLEKLYKSGLVDISSF DWLSQLRFYWEKDLDDCMIRQTNTQFQYSYEYLGNSGRLVITPLTDRCYMTLTTALHLHR GGSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEF NRINVEVLSVVAQQILSILSALAAGLTRFYFEGFEINLVWSCGIFITMNPGYAGRTELPD NLKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGL RALTSLLRYAGKKRRLEPDLSDEEVLLLSMRDMNIAKLTSVDVPLFNAIVQDLFPNIELP VIDYGKLRDTIEQEIRDMGLQSTPFTLTKVIQLYETKNSRHSTMIVGGTGSGKTTSWRTL QASLSSLCRAGEPNFNLVREFPLNPKALSLGELYGEYDLNTNEWTDGVLSSVMRSACADE KPDEKWILFDGPVDTLWIESMNSVMDDNKVLTLINGERIAMPEQVSLLFEVENLAVASPA TVSRCGMVYTDYTDLGWKPYVQSWLEKRLKAEAEPLQRMFEKFINKMLAFKKDYCNELVP LPEYSGIISLCKLYSALATPENGVNPADGENFVSVVEMTFVFSMIWSVCASVDEEGRKRI DSCLREMEGSFPNKDTVYEYFVDPKMRSWTSFEDKLPKSWRYPPNCPFYKIMVPTVDTVR YNYLVSALVASQNPVLLVGPVGTGKTSIAQSVLQSLPSSQWSVLIVNMSAQTTSNNVQSI IESRVEKRTKGVYVPFGGKSMIAFMDDLNMPARDTFGSQPPLELLRLWIDYGFWYDRTKQ TIKYIRDMFLMAAMGPPGGGRTVISPRLQSRFNIINMTFPTESQIMRIFGTMINQKLQDF EEEVKAIGNVVTEATLDVYNTVAQRFLPTPARIHYLFNLRDISKVFQGMLRANKDFHDTK SSITRLWIHECFRVFSDRLVDAADMEAFVGIISDKLGSFFDLTFHNLCPSKRSPIFGDFM REPKVYEDLTDLAVLKAAMETALREYNLSPAAVPMQLVLFREAVEHITRIVRVIGQPRGN MLLVGIGGSGRQSLARLASSICEYITFQIEVSKHYRKQEFREDIKRLYRQVGVELKATSF LFVDTQIADESFLEDINNILSSGEVPNLYKADEFEEIQAHIVEQAKAEQVSQSSDSLFAY LIERVRNNLHIILCLSPVGDPFRNWIRQYPALVNCTTINWFSEWPREALLEVAEKYLVGV DLGTQENIHKKVAKIFVTMHWSVARYSQKMLLELRRYNYVTPTNYLELVSGYKRLLGEKR QELLDQANKLRTGLFKIDETREKVEVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREAD EQQKAVTANSEKIAIEEVKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYG RPPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLIHFDKDNISDKVLKKIGAYCA QPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLQEKQAALAEA QEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMEVKLERAGLLVSGLAGEKARWEETV QGLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWMKKIRELQVPCSPRFTFDNF LSNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGNQGLQII DLQMSDYLRILEKAIQFGYPVLLQNVQEYLDPSLNPVLNKSVTRIGGRLLMRIGDKEVEY NTDFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSL VINIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLRTSKVTASEVTEQLETSETTE INIDLAREAYRPCAQRASVLFFVLNDMGRIDPMYQFSLDAYIGLFILSIDKSHRSNKLED RIDYLNEYHTYAVYRYTCRTLFERHKLLFSFQMCAKILETSGKLNMDEYNFFLRGGVVLD REGQMDNPCTGWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTSATPEKAMLPG EWENACNEMQRMLIVRSLRQDRVAFCVTSFIVSSLGSRFIEPPVLNMKLVLEDSTPRTPL IFILSPGVDPTSALLQLAEHTGMAQRFHALSLGQGQAPIAARLLREGVVQGHWVFLANCH LSLSWMPNLDKLVEQLQVEDPHPSFRLWLSSSPHPGFPISILQASIKMTTEPPKGLKANM TRLYQLMTETQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIVYGFNDSDFEVS ENLLSLYLDEYEETPWDALKYLIAGVNYGGHVTDDWDRRLLTTYINDYFCDQSLSAPFYR LSVLEAYFIPKDGSLASYKEHISMLPGMDPPEAFGQHPNADVASQITEARTLFETLLSLQ PQITPTRAGGQSREEKVLELAADVKQKIPEMIDYEGTRKLLAMDPSPLNVVLLQEIQRYN KLMETILSSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKAYPSQKPLASWTRDL ATRVEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNIPVDNLSWEFIVSTVD DSNLVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPTESRKKSAKG MYSCPCYYYPNRAGSSDRASFVIGIDLRSGTMTSDHWIKRGTALLMSLDN NT seq 13293 nt NT seq  +upstreamnt  +downstreamnt atgtccagcagagcggagaagaagcggaaagtgagtgcccagggaagtgccagtcgcgga ggcacccgcaggagagctgctcaggcggccgcactggcctcgcaggctgcggagaccacc ctggcctctggcgagcccgagctggagcccgagcccgagcccctcaaggaggagcttgag ccaacgctggaggaacccgaagtagagaaggaagagttcccggagcccgaggtggacgtg aagccccttttcctgtcccaggctgtgctgacaggactagcggatgccgtctggacagcg gagcatgatgccattttggaacactttgcccaggacccttcggagctcatcctcaccatc ttcatcgacccgtatatggggctgaagctagatctgggcatgcctgtacagacccagaac cagattgtctacttcattcgctgcgcaccggttcccatcaccccggagaactttgaggca actgtgcagtttgggaccgtgcggggttcctacatcccggccctgctccagctgctcagt ggtgtctttgcccctcagatctttgcaaacacaatctggcctgaaagtattcggaatcat tttgcttctcatctgcacagattcttggcctgcctgacagatactcggtacaaactggag gggcataccgttctctacattcctgcagaggccatgaacatggcacccgaggtggtggtt aaggacaaagagctggtgcagcggctggagacctccatgatccactggacccggcagata aaggaggtgctcagtgcccaggagtctgtggagacaggagaaaatttaggtcctctggag gagattgagttctggcgcaaccgatgcatggacctgtctggcatcagtatgcagctggtg aagcagggagtaaagcacattgaatccatcctgcgtcttgccaagtcctcctacttggcg ccctttatgaaactggcccagcagatccaggatggttctcgtcaagcgcagtcaaacctg acgtttctgtcaatcctgaaggagccctaccaggaactggcctacatgcggcctaaggac atctccagtaagctccccaagctcatcagtctcatccgtatcatctgggtcaactctccc cactacaacactcgggagagactgacctcccttttccgaaaggtatgcgactgccagtac cattttgcccgctgggaggatggcaagcaggctccgcttccttgcttcttcggtgcccag gggccccagatcacacggaacttgctggagattgaggacatctttcataagaatctccac atgcttcgggctgtccgcgggggcatcctggacgtcaagaacacctcctggcacgaggac tacaacaggtttcgcactggagtcaaggacctggaggtgatgactcagaacctgatcacc tctgccttcgagttagtccgagacgtggagcagggggtgctgctgctggacaccttccac aggctcgccacgcgggaggccatcaagcgaacctacgacaagaaggcggtggatctctac atgctgttcaataccgagctggccctggtgaaccgtgagctgaacaagaaatggctgttc ctggagccctacatggcccagtactcgggacaggcgcactggatgcggatcctgcgacat cgcatcgacagggtcatgaactgtctctccagcgctcacttcctgccccacattggaacc ggagaggagagcgtgcacacctatcagcagatggttcaggccattgacgagctggttcgg aagaccttccaagactggacgctaacgctggacaaggactgcatccggcggctggacacg ccactgttacgaatcagccaggagaaggcgggcatgctggatgtcaacttcgacaagtcc ctgctgattctctttgtggagattgactactgggaacggctgctctttgagacgccccac tacgtgatgaacgtagccgagcgtgcggaggacctgcgcattcttcgggaaaacctgttg cttgtggctcgagactacaaccgaatcattgccatgctgtccccagacgagcaggccctc ttcaaagaacgtatccgattcctggataagaagatccaccctggactcaagaaactgcac tgggccttgaagggggccagtgccttcttcatcacagagtgccgcatacacgccagcaag gtgcagaccatcgcgaatgagttcaaggcctccactctgaccattggctggcgagcgcag gagatctccgagacactgttggtacgcatcagcggcaaacgggtgtacagggacctggaa tttgaggaggaccagcgggaacaccgagcagccgtgcaacagaaattgatgagcctgcac caggacgtggtggccatcatgaccaactcctacgaagtcttcaagaatgacggccctgag attcagcagcagtggatgctgtacacgattcggctggaccgcatgatggaggacgccctg cgtctgaacgtgaagtggtcgctgctggaactgtccaaggccatcaacggggatggaaag accacacccaaccccctcttccgagtcctggtcattttgcagaatgacatgcagggagtg gcacaggtggagttctcacccactctgcagactctggcaggtgtggtcaatgacattggt caccacctcttctccaccatctctgtcttccgccacctccccgaaattctcatcaggcgg aagtttcatcgtgaccccatccatataatcgtggagcgagacgaggatatcaagaagatc caggcgcagatcagcagcggcatgaccaacaatgcgagccagctgcagaactacctcaag acctgggatttgtatcgggagatctgggagatcaacaaggactcttttattcgccgctat cagcgtctcaacccgcccgtctcttcttttgatgccgacattgcccgctacacggaggtg gccaataacgtgcagaaggaggagacggtgctcaacatccagttcgtgctgctagactgc tcccacctcaagttctcgctggtgcagcactgtagcgagtggcagaacaagttcacgact ctgctcaaggagatggcggcccggcgcctcctggagctccatacctacctgcgggacaac ggggagaaaatcagccgccctccgcagacgctggaggaactgggggtcagtttgcagctc atggagaccctgcagcatgacctgcccaacctggagacccagattccccccatacacgag cagttcaccatccttgagaagtacgaggtgccagttcaggagaacgtcctggagatgctg gacagtctcaatggggagtgggtcaccttccaacaaattctgttggacagtgagcaaatg ctgaagaaacacaaggagaaattcaagacaggcctcatccactcagcagatgatttcaag aagaaggcacataatcttctggaagactttgaatccagaggccccttcaccagtaacgtg ggacatcaggcggccttggagcagattgctcaggtgcgggccatgctgaatgccatgcag gaagaagaaaacagtctccgctccaacctgggcatcttcaagatcgagcagccagcctcc aaggacctgcagaacctggagaaggagctggacgcgctccagcaagtgtgggagatcacg cgggactgggaggagaactggaaccagtggaagaccggccggttcctgaccctgcagaca gaggccatggagacaatggcgcatggcctattccgccgtctcaccagactatccaaagaa tacaaggaccgcaactgggaaattattgaaaccacccgatccaaaatagagcagttcaag aggaccatgcctctcatctcggaccttcgcaaccccgccctcagagagaggcactgggat caggtcagggatgagatccaacgggagtttgatccggaatctgagagcttcaccttggag cagattgtggaccttgggatggaccagcacgtggagaaaatcggggagatctctgcatca gccaccaaagagctggctatagagttggcattacagaacattgccaagacctggagtgtg attcagctagacatagttccctataaggacaagggccaccacagactccgaggcacagag gaggtgttccaggccctggaagataaccaggtggctctgtctaccatgaaggcttcccgt tttgtcaaggccttcgagaaggaagtggaccactgggagcgctgcctctccctcatcttg gaggttgttgagatggtgcttaccgtgcagcgccagtggatgtacctcgagaatatcttc ctgggagaggacatccgtaagcagctgcccagtgaatcagccctatttgaccaggtcaac aacaactggaaatccatcatggatcgcttgagcaaggacagcaacgctctggagagcacc caccacccaggcctgctggacacattgatagaaatgaacacagttctggaagacattcag aagtctctggatatgtatctagagaccaagcgccatgtctttccccgcttctacttcctg tccaacgatgacctcctggagattctgggccagtcccgcaacccagaggctgtgcagccg cacctcaaaaaatgctttgacaacatcaagttgctgagaatgcagaaggttgggggacct ggcagcaaatgggaagctgtgggaatgttctcgggtgacggcgagtatgttgacttcctc cacacagtccttctggaagggcctgtggagtcctggcttggtgatgtggagcggactatg agggtgaccctacgggacctcctccggaactgtcgcctggccctcaagaagtttctcaac aagagggacaagtgggtgaaggagtgggctggccagatggtgatcgctgccagtcagatc cagtggacggctgacgtcaccaagtgcctgctgacggccaaggagcgaggagacaagaaa atcctcaaggtcctgaagaagaagcaggtgtccgtcctgaacaagtattcggaagccatc agggggaacctgaccaaaatcatgcggctgaaaattgtggcgctggtgacgatagaggtg cacgcccgggacgtgctggagaagctgtacaagagtggcctcgtggacatcagctccttc gactggctcagtcagctgcgcttctactgggagaaggatctggacgactgcatgatccgc cagaccaacacgcagttccagtacagttacgagtacttggggaactctggccggctcgtc atcaccccactgacggacaggtgttacatgactctgaccacggccctgcacctgcatcgg gggggctcccccaaaggcccggcgggcacggggaagacagagactgtcaaggacctcggc aaggccctcggcatatacgtcattgtggtcaactgctccgagggcctggactacaagtcc atgggcaggatgtactcaggcctggcccagaccggcgcctggggctgctttgacgagttt aaccgcatcaacgtggaggtgctgtcagtggtggcccagcagattctgtccatcctgtcc gccctggccgccggcctcacccgcttctacttcgagggctttgaaataaacctggtgtgg tcctgtgggatcttcatcaccatgaaccccggctacgccggtcgcacggagctgccggat aacctgaaatccatgttccgtcccatcgccatggtggtccctgattccactcttatcgca gagatcattctcttcggggagggctttgggaactgcaagattctggccaagaaggtatac accctctactcgctggccgtgcagcagctctccaggcaggaccattacgacttcggcctg cgcgccctcacctccctcctgcgctacgcgggcaagaagcgccgtctggagccggatctg tccgatgaagaggttttgctgctctcgatgcgagacatgaacatcgccaagctcacctca gtcgacgtgccgctcttcaacgccatcgtgcaagacctgttccccaacatcgagctgcct gtcattgactatggcaagctgcgggacaccatcgagcaggagatccgagacatgggccta cagagcacaccgttcaccctcaccaaggtcatccagctgtacgagaccaagaactcccgc cactccaccatgatcgtgggcggcacgggcagtggcaagacgacatcgtggcgcaccctt caggcctccctgtcctccctgtgccgcgccggagagcccaacttcaacctcgtccgggag ttccccttgaaccctaaggcgttgtccctaggggagctgtatggggaatatgacctcaac acaaacgagtggacggatggcgtcctgtccagcgtcatgcgatcggcgtgtgcagatgag aagccggacgagaagtggatccttttcgacggccccgtggacacactgtggatcgagagc atgaactcggtcatggacgacaacaaagtcctgaccctcatcaacggggagcgcatcgcg atgcccgagcaggtgtctctcctgttcgaagtggagaacttggccgtggcctctcccgcc accgtgtctcgctgtgggatggtctacaccgactacactgacctgggctggaagccctac gtgcagtcctggctggagaagaggctaaaggccgaggcagagccccttcagcgcatgttc gagaagttcattaacaagatgctggccttcaagaaggactattgcaacgagttggtgccc ctcccggaatacagtgggatcatctccctctgcaagctgtactcggccctggccacgcca gagaacggggtgaacccagccgacggtgaaaactttgtctctgtggtggagatgaccttc gtgttcagcatgatttggtccgtatgcgcctccgtggatgaggagggacgcaagaggatc gacagctgcctccgagagatggagggctcctttcccaataaggacacggtgtatgagtac tttgtggaccccaagatgcggagctggacgtcatttgaggataagctccctaagagttgg cgctaccctcccaactgccccttctataagatcatggtgcccacggtcgacaccgttcgc tacaactacctggtgagcgccctggtggccagccagaaccccgtcctgctggtgggcccc gtggggaccgggaagacgtccatcgcccagagcgtcctgcagtccctgccctccagccag tggtccgtgctcatcgtcaacatgtccgcgcagaccacttccaacaacgtgcagagcatc atcgagagcagggtggagaagcgaaccaagggcgtctacgtgcccttcggaggcaagagc atgatcgccttcatggacgacctaaacatgcccgcgagggacacgttcgggtcccagccc ccgctggagctgctccgtctctggattgactacggcttctggtacgaccgcacgaagcag accatcaagtacatccgagacatgttcctgatggctgccatgggcccccccgggggcgga cggactgtcatctccccaaggctccagagtcgcttcaacatcatcaacatgaccttcccc acggagtcccagatcatgcgaatattcggcaccatgatcaatcagaagctccaggacttc gaggaggaggtgaaggccatcgggaacgtggtgaccgaggccaccttggatgtttataac acggtggcacagcgcttcctgcccacacccgccaggatccactatctcttcaacctgcgg gacatctccaaggtgttccagggcatgctcagggccaacaaggacttccacgacaccaag tccagcatcacacgactctggatccatgagtgtttcagagtcttctcggaccggctggtg gatgcagccgacatggaggccttcgtgggcatcatcagcgacaagctcggctccttcttt gacctcacgtttcataatctctgtcccagcaagcgttctccgatcttcggggacttcatg agggagcccaaggtgtacgaggacctgaccgacctggcggtactgaaggcggccatggag acagcgctccgggagtacaatctgtcccctgcagcggtgcccatgcagctggtgctcttc cgagaggctgtagaacacatcacgcggattgtgcgggtcatcggacagcctcggggcaac atgctcttggtgggcatcgggggcagcgggcgccagagtctggcccgcctggcctcctcc atctgcgagtacatcaccttccagatcgaggtcagcaaacattaccgaaagcaggagttc cgagaagatatcaagcgtctgtaccgccaggtgggagtagagctcaaggccacgtccttc cttttcgtggacactcagatcgccgatgagtcgttcctggaggatatcaacaacatcctg agctcaggggaggtccccaatctctacaaagctgatgaattcgaagagatccaggcgcac atcgtggagcaggccaaggccgagcaggtgtctcagtcctccgacagcctcttcgcctac ctcatcgagcgcgtgcgcaacaacctgcacatcattctctgcctcagccccgtgggcgac cccttcaggaactggatccgccagtacccagccttggtgaactgcacgaccatcaactgg ttctcagagtggccccgtgaggccctgctggaggtggccgagaagtacctcgtgggggtg gacctggggacgcaggagaacatccacaagaaggtggccaagatcttcgtcaccatgcac tggtcggtggctcggtactcccagaagatgctgttggagctgcggagatacaactacgtc acgcccaccaactacctggagctcgtgtccggatacaagaggttgctgggagagaagcgg caggagctgctggaccaggccaacaagctgcggaccggactgtttaagatcgacgaaacc agagagaaggtggaagtgatgtccctggagctggaggacgccaagaagaaggtggctgag ttccagaagcagtgcgaggagtacctggtcatcatagtgcagcagaagcgagaagcggat gagcagcagaaggcggtcacagccaatagtgagaagattgccatcgaggaagtcaagtgc caggcactggctgacaatgcccagaaggatctagaagaggccttgccagccctggaggaa gccatgcgggccctggagtccctgaacaagaaggatataggagagatcaagtcttacgga cggccccctgcccaagtggaaatcgtgatgcaggccgtcatgattcttcgaggcaacgag cccacgtgggcagaggccaagaggcagctaggggagcagaacttcatcaagtctctgatc cactttgataaagacaatatctcagataaggttctgaagaagattggggcctactgtgcg cagcccgacttccagcctgacatcatcggccgagtctcgctcgccgccaagtccctgtgc atgtgggtgcgcgccatggagctgtatgggcgcctgtatcgcgtggtggagcccaagagg attcggatgaacgctgccttggcccagcttcaggagaagcaagcagcactggctgaggcc caggagaagctgcgggaggtggctgagaaactggagatgctgaagaaacagtacgacgag aagctggcccagaaggaggagctgcgcaagaagtctgaggagatggaggtgaagctggag cgcgcggggctgctggtgtccgggctggccggcgagaaggcacggtgggaggagacggtg cagggcctggaggaggatctgggctacctggtaggtgactgtctcctggctgctgccttc ctgtcctacatgggccccttcctgaccaactaccgtgacgagatcgtcaaccagatctgg atgaagaagatccgggagcttcaggtcccttgctcacctcgcttcacctttgataacttc ctgtccaatcctaccaaagttcgagattggaacatccaagggttgccctcggatgccttt tccaccgagaatggcatcatcgtgacccgtggcaacaggtgggcactgatgattgaccct caggcccaggccctgaagtggatcaagaacatggaaggaaaccagggtctccagattatc gacctgcaaatgagcgattaccttcgaattctagaaaaggccatccagtttggataccca gtgctgctccagaatgtgcaggaatatctggacccctcgctcaaccctgtgctcaacaaa tctgtaactcgaattggtggtcggctgctgatgcgcattggagacaaggaggtggagtac aatacagatttccggttctacatcaccaccaagctctccaacccccattacagcccagag acttcggccaagaccaccattgtcaactttgctgtcaaagaacagggcctggaggcccag ctgctgggcatcgtggtccggaaggagcggccggagctggaagagcagaaggattcactg gtcatcaatattgctgctggcaagaggaagctcaaggagctggaggacgagatccttcgg ctgctgaacgaggccacaggctccctgctggacgacgtgcagctggtgaacacccttcgg acctccaaggtgacggccagcgaggtgacggagcagctggagaccagtgagaccacggag atcaacatcgacttggcccgcgaggcctaccgcccctgcgcccagcgggcctccgtgctg ttcttcgtgctcaacgacatgggccgcatcgaccccatgtaccagttctcgctggacgcc tacatcggcctcttcatcctcagcatcgacaagagccaccgcagcaacaagctggaggac cgcatcgactacctgaacgagtaccacacctacgcagtctacaggtacacctgtcgcacg ctttttgagcgccacaagctgctgttcagtttccagatgtgtgccaaaatcctggagacc tctggcaagctcaacatggacgagtacaacttctttctgcgcgggggcgtggtgctggat cgggagggccaaatggacaacccgtgtaccggctggctggcggacgcctactgggataac atcacagagctggacaagctgaccaacttccacggactcatgaactcctttgaacagtac cctcgtgactggcacctgtggtacaccagtgccaccccggagaaggccatgctgccaggt gagtgggagaacgcctgcaacgagatgcagcggatgctgatcgtgcgctccctgcgccag gaccgcgtggccttctgcgtcacgtccttcatcgtgtccagcctaggctcccgcttcatc gagccgccggtgctaaacatgaagctggtgttggaggattcgaccccgcgaaccccgctg atcttcatcctgtcccccggcgtggatcccaccagcgccctgctgcagctggcagagcac acgggcatggcccagcgcttccacgccctgtccctgggccagggccaggcccccattgct gctcggcttctccgggagggtgtggtccagggacactgggtgtttctagctaactgccac ctgtcactgtcttggatgcccaatctggacaagctggtggagcagctgcaggtggaagat cctcacccttccttccgcctctggctcagctctagcccccacccgggcttccctatctcc atcttgcaggccagcatcaagatgaccacggaaccgccgaagggcctgaaggccaacatg acacgtctttaccagctgatgacggagacacagttttcccgctgctccaaacctgccaag tataagaagctgctgttttcactctgcttcttccattctgtgttgctggaacgtaaaaag ttcctgcagcttggctggaacattgtctatggcttcaatgactccgacttcgaggtgtcc gagaacttgctgagtctctacctggacgagtatgaggagacaccgtgggacgcgctcaag tacctcattgccggcgtcaactacggcgggcacgtcacggacgactgggaccggcgtctg ctcaccacctacatcaacgactatttctgtgaccagtctctgtcagcccccttttaccgg ttgtcggtgttggaggcttacttcatccccaaagatgggagcctggcctcttacaaggag cacatcagcatgttgccgggcatggaccccccagaggcctttggccagcaccccaatgcg gatgtggcctcccagatcaccgaggcacgaactctctttgagactctgctttccctgcaa ccccagattacacccaccagggctggaggccagagccgggaagagaaggtcctcgagttg gccgctgacgtgaaacagaagatccctgaaatgatcgactatgaggggacccgaaaactg ctggccatggacccttcccccctcaatgtggtcctcctgcaggagatccagagatacaac aagcttatggagaccatcctgtcctcactgacagacctcgaaaaaggcattcagggcctc atcgtcatgtctacaagcctggaagagattttcaattgcatcttcgatgcccatgtccct ccactctggggaaaggcatatccctcacaaaagccgctggcttcgtggacccgggacttg gccacgcgcgtggaacagttcgagctgtgggccagccgagcccggcctcctgtcatcttc tggctgtctggcttcacctttcccaccggcttcctcactgctgtgctgcagtcctcagct cgccaaaacaacattccagtggacaacctctcttgggagttcattgtttccaccgtggac gacagcaacctagtgtatccacccaaggacggcgtctgggtccgtggcctgtacctggag ggcgccggctgggaccggaagaactcctgcttggtggaggcagagcccatgcagcttgtc tgcctcatgcctacgatccacttccggcctaccgaaagtcgaaagaagagcgccaagggc atgtactcctgtccctgctattattaccccaaccgggcgggcagctcagaccgcgcctcc tttgtcatcggcattgacctccggtctgggaccatgacgtctgaccactggatcaagagg ggcactgctctgctcatgagcctggacaactga

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