Ursus americanus (American black bear): 123792667
Help
Entry
123792667 CDS
T07931
Symbol
ARHGEF12
Name
(RefSeq) rho guanine nucleotide exchange factor 12 isoform X1
KO
K07532
Rho guanine nucleotide exchange factor 12
Organism
uar
Ursus americanus (American black bear)
Pathway
uar04270
Vascular smooth muscle contraction
uar04360
Axon guidance
uar04611
Platelet activation
uar04625
C-type lectin receptor signaling pathway
uar04810
Regulation of actin cytoskeleton
uar05135
Yersinia infection
uar05152
Tuberculosis
uar05163
Human cytomegalovirus infection
uar05200
Pathways in cancer
uar05205
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
123792667 (ARHGEF12)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
123792667 (ARHGEF12)
04625 C-type lectin receptor signaling pathway
123792667 (ARHGEF12)
09153 Circulatory system
04270 Vascular smooth muscle contraction
123792667 (ARHGEF12)
09158 Development and regeneration
04360 Axon guidance
123792667 (ARHGEF12)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123792667 (ARHGEF12)
05205 Proteoglycans in cancer
123792667 (ARHGEF12)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
123792667 (ARHGEF12)
09171 Infectious disease: bacterial
05135 Yersinia infection
123792667 (ARHGEF12)
05152 Tuberculosis
123792667 (ARHGEF12)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
uar04131
]
123792667 (ARHGEF12)
Membrane trafficking [BR:
uar04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
123792667 (ARHGEF12)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RGS-like
PH_16
RhoGEF
PDZ
PDZ_6
PDZ_2
PH_13
SOS1_NGEF_PH
Pept_S41_N_bact
COS
AAA_23
Motif
Other DBs
NCBI-GeneID:
123792667
NCBI-ProteinID:
XP_045653943
LinkDB
All DBs
Position
Unknown
AA seq
1543 aa
AA seq
DB search
MSGTQSTITDRFPLKKPIRHGSILNRESPTDKKQKVERSASHDFDPTDSSSKKTKSSSEE
SRSEIYGLVQRCVIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGT
LVTHSNHLEVVKLIKSGSYVALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSPHSPG
ASGNMERITSPVLMGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQ
EAKKHIPQLQEQLSKATGSAQDGAAVTSSKPLGDALTVSEVEADPSDGLSRIDSSSGDAS
RPSSDSADSPKSALKERIYLEENAEKSEVIQDTDTQSLIGSPSPRIAPHIIGAEDDDFGT
EHEQINGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKQTNSKETRR
VFLEFHQFFLDRSAHLKVSVPDEISVDLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHL
EDFRQKRSMGLTLAESELTKLDAERDKDRVTLEKERACAEQIVAKIEEVLMTAQAVEEDK
SSTMQYVILMYMKHLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDREGEEKGKRRGFPSI
LGPPRRPSRHDNSAIGRAMELQKQRHPKHLSTPSSVSPEPQDPAKLRQSGLAGEGTDVGY
LPANSMSSVASGATLSQEGGKENDTGSKQLGETPASGDCVDGTPRTPNTVFDFPPPPLDQ
VQEEEWEVERVTEHGTPKPFRKFDSIAFGESQSEDEQFENDLETDPPNWQQLVSREVLLG
LKPSEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQ
LHIGLNEQMKSVRKRNETSVIDQIGEDLLTWFSGPGEDKLKHAAATFCSNQPFALEMIKS
RQKKDSRFQTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPTEREKV
KKAADHCRQILNYVNQAVKEAENKQRLEDYQRRLDTSNLKLSEYPNVEELRNLDLTKRKM
IHEGPLVWKVNRDKTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVI
KLSTVLVRQVATDNKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSAK
PIPLPQSPPCEGDNDEEAAPKLKVGHHSISVPGLQSPDRDLGLESPLMSSKPQSHSLGTS
GKSEVDDLFVAERQFAKEQHADGTLQEAGASYQIPIPDPHLPASEERWALDALRNLGLLK
QLLVQQLGLTEKSTQEDWPHFPRYRTASSGVQTNGGAQNSENSKACPPGEGQMPFRTGIG
DIATCYSPRTSAESSAPRDSVVLAFQDSQASNILVMDHMVMTPEMPPAEPEGSLDESGEH
FFDAREAHSDDNPSEGDGAVRKEEDVTLRISGNYLILDGYEAVQESSTDEDVASSLPPPP
PAGIPSTDSARPHQHSPQRAHSDGAASPFTPEFLLQQRWGAMEDSCFEIQSPPSCADSQS
QIMEYIRKIEADLEHLKKVEESYSMLCQRLAGSALTDKHSDKS
NT seq
4632 nt
NT seq
+upstream
nt +downstream
nt
atgagtggcacacagtctactatcaccgacaggtttcccctcaaaaaacctataaggcat
gggagtattttgaaccgagagtcaccaacagataagaagcagaaagttgagcgcagtgca
tcacatgattttgatcctacagatagctcctccaagaagacaaagtctagttcagaggag
agtagatccgagatatatggtcttgttcagcgttgcgtgatcatccagaaggatgacaat
ggatttgggctgacggtcagtggagacaatccagtcttcgtacagtctgtcaaagaagat
ggagcagccatgcgggctggggtacagacaggtgatcgaatcatcaaggtgaatggaact
ctggtgactcattcaaaccatttggaagtggtgaagctaatcaaatctggttcctatgta
gctctcactgttcagggacgcccacctgggtcgccccagattccactcgccgattctgaa
gtagagccatcagtcattggacatatgtctcccatcatgacatcccctcattcacctgga
gcatctgggaacatggagagaattactagtcctgtgctcatgggggaggaaaacaatgtg
gttcataaccagaaagtagaaattctgagaaaaatgttacagaaagaacaggaacggcta
cagttattgcaggaagattacaaccgaacacctgcccaaagattgctaaaagagatccaa
gaggccaagaaacacattcctcagctgcaagagcagttatccaaagccacgggctctgct
caggatggagctgcagttacatcctccaagcctttaggtgacgcactgacagtcagtgag
gtggaagctgatcctagtgatggactaagcagaattgactctagcagtggagacgcttct
cggcccagtagtgacagcgcagacagtcccaagagtgccctgaaagagaggatttatcta
gaggaaaacgcagagaaaagcgaagtgattcaggacactgatactcagtcactcatcggg
agtccctctccccgtatagcacctcatattattggagcagaggatgatgatttcggtact
gaacatgaacagatcaatgggcagtgcagctgtttccagagcatcgagctgctgaaatct
cgccctgctcacctggctgttttcttacaccacgtggtctcacagtttgaccccgcgacg
ctgctgtgttatctctattcagacctgtacaagcagaccaattccaaggagactcgtcgt
gtcttccttgagtttcatcagttcttcctggatcgatctgcacacctgaaagtttctgtg
cctgatgaaatatcagtagatctagaaaaaagaagacctgagcttatacccgaggatctg
caccgccactatatccaaactatgcaggaaagagtccacccagaagttcagaggcacttg
gaagattttcggcagaagcgtagcatggggctgaccttggctgaaagcgaactgactaaa
cttgatgcagagcgagacaaggaccgggtcactttggagaaggaacgggcatgtgcagaa
cagatcgttgccaaaattgaagaagtgttgatgactgctcaggctgtagaagaagataag
agttcaacaatgcagtatgttatccttatgtacatgaagcatttgggggtaaaagtgaaa
gaacctcgaaatttggagcacaagcggggtcggattggattccttccaaaaatcaagcag
agtatgaagaaagatcgagaaggcgaagaaaaagggaagcgcagaggattccccagcatc
ctgggacccccaaggagaccaagccgtcatgacaatagtgcaattggcagggccatggag
ctacagaaacagcggcacccaaagcacttatccacaccctcttccgtgagtcctgagcct
caggaccctgctaagttgcgccagagtgggttagcaggtgaaggaacggacgtcggatac
ctgccagccaattccatgtcctctgtggcttcaggggccactctttcccaggaaggaggg
aaagagaatgatacaggatcaaagcaacttggagaaacaccagcatctggagactgcgta
gatggcacccctcggactccgaatactgtctttgatttcccacctcctcctctggaccaa
gtgcaggaggaggaatgggaagtggaaagggtgactgaacatgggacaccaaagcccttt
cgaaagtttgacagcatagcttttggagaaagtcaaagtgaggatgaacagtttgaaaat
gacttagagacagacccaccgaactggcaacagctcgttagtcgagaagtgttactggga
ctaaagccttctgagatcaaaagacaggaagtaattaatgaattgttctacactgaaaga
gctcatgttcgaacactgaaagttcttgatcaagtattctatcagcgagtgtccagagaa
ggaattctgtcaccttcagaactacggaaaattttttcaaacttggaagatattcttcaa
cttcatattggattgaatgagcaaatgaagtctgttcgaaagaggaatgagacctcagtt
attgatcagattggggaagatttgctgacctggttcagtggaccaggagaggacaagttg
aagcacgctgctgctaccttttgcagtaaccagcctttcgccctggaaatgatcaagtct
cgtcagaaaaaggattctcgattccagacctttgtgcaagatgctgagagtaatcctctg
tgtcgtcgtctgcagctgaaggatatcattcctacccaaatgcagaggcttaccaagtac
cctcttctgttggataatattgccaaatacacagaatggccaacggaaagggagaaggtg
aagaaagctgcagatcactgtcgtcagatcttgaattatgtaaatcaggctgtcaaggag
gcagaaaataaacagcgtttagaagactatcagcgtcgtctggatacctccaatctgaag
ttgtcagagtacccaaacgtggaagagctcaggaatttggatttaacaaaaaggaagatg
attcatgaagggccattggtctggaaggtgaaccgagataaaactattgatctatacacg
ttgctgctggaagacattcttgtattgttacaaaagcaggatgacagactggtgttaaga
tgtcatagtaagattctggcgtctaccgctgacagcaaacacacatttagccctgtcatt
aagttgagtacagtgttggttcgacaagtggcaacagataacaaagctttatttgtcatc
tctatgtcagacaatggagcccaaatttatgaactggtggcacagacagtttccgaaaag
actgtctggcaagacctaatctgtcggatggccgcatccgtgaaggaacaatccgcaaag
cccatcccgttgccacagtcaccaccttgcgaaggagacaacgatgaagaagcagctcca
aagttaaaggtgggacaccacagcatttcggtccctggtctgcagagtccagacagagat
ttgggattagagtctcccttaatgtcgtcaaaacctcagtctcattcactggggacctct
gggaaatccgaggtagatgatctgtttgtggccgagaggcagtttgctaaggagcagcat
gcagatgggactctgcaggaagccggagcaagttatcagatcccaatcccagacccacac
ttgcctgcctcggaagaacggtgggcactggatgcactgaggaatttgggcttgctgaag
cagttgctagtccaacagctgggtttgactgagaagagcactcaggaagactggccacat
ttcccaagatacaggacagcgtcttcaggggtgcagacaaacggtggagcccagaactct
gagaatagtaaggcctgtcctcctggtgaaggacagatgccctttagaactggaattggt
gacattgcaacttgttacagtccacggacttcagctgaatcttcggctccgcgggattca
gtggtactggcattccaagatagccaggcaagtaacattttagtaatggaccacatggtt
atgaccccagagatgcctcctgcggagccagaagggagtctcgatgagagtggagagcac
ttttttgatgcccgtgaagcacatagtgatgataacccatcagaaggtgatggggcggtt
cggaaggaagaggatgttactttgcgcatctcaggaaactatctgattcttgacggctat
gaagcggtgcaggagagctccacggatgaggacgttgcttcctcgctccccccgccgccc
ccggcaggcatcccctccacagactctgctcgcccgcaccagcactcgccccagcgtgcc
cattccgacggggcggcttcaccgttcacccccgaattcctgctccagcagcgctggggg
gctatggaggattcctgttttgagatccagagtcccccctcttgtgcagactctcagagc
cagatcatggagtacattcggaagatcgaggctgaccttgaacacttaaagaaggtggaa
gaaagttacagcatgctttgccaaaggctggctggatcagccctcacagacaagcactca
gataaaagttag
DBGET
integrated database retrieval system
