KEGG   Ursus americanus (American black bear): 123793759
Entry
123793759         CDS       T07931                                 
Symbol
AKR1A1
Name
(RefSeq) aldo-keto reductase family 1 member A1
  KO
K00002  alcohol dehydrogenase (NADP+) [EC:1.1.1.2]
Organism
uar  Ursus americanus (American black bear)
Pathway
uar00010  Glycolysis / Gluconeogenesis
uar00040  Pentose and glucuronate interconversions
uar00053  Ascorbate and aldarate metabolism
uar00561  Glycerolipid metabolism
uar00620  Pyruvate metabolism
uar01100  Metabolic pathways
uar01240  Biosynthesis of cofactors
uar05208  Chemical carcinogenesis - reactive oxygen species
Module
uar_M00014  Glucuronate pathway (uronate pathway)
uar_M00129  Ascorbate biosynthesis, animals, glucose-1P => ascorbate
Brite
KEGG Orthology (KO) [BR:uar00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    123793759 (AKR1A1)
   00040 Pentose and glucuronate interconversions
    123793759 (AKR1A1)
   00053 Ascorbate and aldarate metabolism
    123793759 (AKR1A1)
   00620 Pyruvate metabolism
    123793759 (AKR1A1)
  09103 Lipid metabolism
   00561 Glycerolipid metabolism
    123793759 (AKR1A1)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    123793759 (AKR1A1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:uar04147]
    123793759 (AKR1A1)
Enzymes [BR:uar01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.2  alcohol dehydrogenase (NADP+)
     123793759 (AKR1A1)
Exosome [BR:uar04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   123793759 (AKR1A1)
SSDB
Motif
Pfam: Aldo_ket_red LETM1_RBD
Other DBs
NCBI-GeneID: 123793759
NCBI-ProteinID: XP_045655632
UniProt: A0A452QWC6
LinkDB
Position
Unknown
AA seq 325 aa
MAASCVVLHTGQKMPLIGLGTWKSDPGQVKAAVKYALSVGYRHIDCAAIYGNETEIGEAL
KENVGPGKVVPREELFVTSKLWNTKHHPEDVEPALRKTLAELQLEYLDLYLMHWPYAFER
GDNPFPKNADGTIRYDSTHYKETWKALEALVAKGLVRALGLSNFSSRQIDDVLSVASVRP
AVLQVECHPYLAQKELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVILALAEK
YGRSPAQILLRWQVQRKVICIPKSITPSRILQNIQVFDFTFSLDEMKQLDALNKNWRYIV
PMLTVDGKRVPRDAGHPLYPFNDPY
NT seq 978 nt   +upstreamnt  +downstreamnt
atggcggcttcatgtgtcgtcctgcacactgggcagaagatgcccctgattgggctgggc
acctggaagagcgatcctggccaggtgaaagcagctgttaagtacgccctgagtgtaggc
taccgccacattgactgtgctgctatctatggcaatgagactgagatcggggaggccctg
aaggagaatgtgggacctggcaaggtggtgcctcgagaggagctgtttgtgacttctaag
ctgtggaacactaaacaccaccctgaggatgtggagcctgccctccggaagacgctggct
gagctccagttggagtatttggacctgtacctgatgcactggccctatgcctttgagcgg
ggagacaaccctttccctaagaatgccgatgggactatccgctatgactctacccactac
aaggagacctggaaagcgctggaagcactggtggcgaaggggctggtacgggcactgggc
ctgtccaacttcagcagtcggcagatcgatgatgtgctcagtgtggcctcggtgcgccca
gctgtcctgcaggtggaatgtcacccatacttggctcagaaggagctgattgcccactgc
caagcacgcggcctggaggtgacggcttatagccctcttggctcctctgatcgagcttgg
cgtgatcctgatgaaccggtcctacttgaggagccagtgatcctggcactggctgaaaag
tatggccggtctccagctcagatcctgctcaggtggcaggtccagcggaaagtgatctgc
atccccaagagtatcaccccttcacgtatcctccagaacatccaggtgtttgactttact
tttagcctggacgagatgaagcagctagatgccctgaataaaaattggcgatacattgtg
cccatgctcacagtggatgggaagagagtcccgagagatgcagggcaccctctgtacccc
tttaatgacccatactga

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