KEGG   Ursus americanus (American black bear): 123793902
Entry
123793902         CDS       T07931                                 
Symbol
NFKBIA
Name
(RefSeq) NF-kappa-B inhibitor alpha
  KO
K04734  NF-kappa-B inhibitor alpha
Organism
uar  Ursus americanus (American black bear)
Pathway
uar04024  cAMP signaling pathway
uar04062  Chemokine signaling pathway
uar04064  NF-kappa B signaling pathway
uar04210  Apoptosis
uar04380  Osteoclast differentiation
uar04620  Toll-like receptor signaling pathway
uar04621  NOD-like receptor signaling pathway
uar04622  RIG-I-like receptor signaling pathway
uar04623  Cytosolic DNA-sensing pathway
uar04625  C-type lectin receptor signaling pathway
uar04657  IL-17 signaling pathway
uar04658  Th1 and Th2 cell differentiation
uar04659  Th17 cell differentiation
uar04660  T cell receptor signaling pathway
uar04662  B cell receptor signaling pathway
uar04668  TNF signaling pathway
uar04722  Neurotrophin signaling pathway
uar04920  Adipocytokine signaling pathway
uar04926  Relaxin signaling pathway
uar04931  Insulin resistance
uar04936  Alcoholic liver disease
uar05132  Salmonella infection
uar05134  Legionellosis
uar05135  Yersinia infection
uar05140  Leishmaniasis
uar05142  Chagas disease
uar05145  Toxoplasmosis
uar05160  Hepatitis C
uar05161  Hepatitis B
uar05162  Measles
uar05163  Human cytomegalovirus infection
uar05164  Influenza A
uar05166  Human T-cell leukemia virus 1 infection
uar05167  Kaposi sarcoma-associated herpesvirus infection
uar05168  Herpes simplex virus 1 infection
uar05169  Epstein-Barr virus infection
uar05170  Human immunodeficiency virus 1 infection
uar05171  Coronavirus disease - COVID-19
uar05200  Pathways in cancer
uar05203  Viral carcinogenesis
uar05208  Chemical carcinogenesis - reactive oxygen species
uar05215  Prostate cancer
uar05220  Chronic myeloid leukemia
uar05222  Small cell lung cancer
uar05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
uar05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:uar00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    123793902 (NFKBIA)
   04668 TNF signaling pathway
    123793902 (NFKBIA)
   04024 cAMP signaling pathway
    123793902 (NFKBIA)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    123793902 (NFKBIA)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    123793902 (NFKBIA)
   04621 NOD-like receptor signaling pathway
    123793902 (NFKBIA)
   04622 RIG-I-like receptor signaling pathway
    123793902 (NFKBIA)
   04623 Cytosolic DNA-sensing pathway
    123793902 (NFKBIA)
   04625 C-type lectin receptor signaling pathway
    123793902 (NFKBIA)
   04660 T cell receptor signaling pathway
    123793902 (NFKBIA)
   04658 Th1 and Th2 cell differentiation
    123793902 (NFKBIA)
   04659 Th17 cell differentiation
    123793902 (NFKBIA)
   04657 IL-17 signaling pathway
    123793902 (NFKBIA)
   04662 B cell receptor signaling pathway
    123793902 (NFKBIA)
   04062 Chemokine signaling pathway
    123793902 (NFKBIA)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    123793902 (NFKBIA)
   04926 Relaxin signaling pathway
    123793902 (NFKBIA)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    123793902 (NFKBIA)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    123793902 (NFKBIA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123793902 (NFKBIA)
   05208 Chemical carcinogenesis - reactive oxygen species
    123793902 (NFKBIA)
   05203 Viral carcinogenesis
    123793902 (NFKBIA)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    123793902 (NFKBIA)
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    123793902 (NFKBIA)
   05215 Prostate cancer
    123793902 (NFKBIA)
   05222 Small cell lung cancer
    123793902 (NFKBIA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    123793902 (NFKBIA)
   05170 Human immunodeficiency virus 1 infection
    123793902 (NFKBIA)
   05161 Hepatitis B
    123793902 (NFKBIA)
   05160 Hepatitis C
    123793902 (NFKBIA)
   05171 Coronavirus disease - COVID-19
    123793902 (NFKBIA)
   05164 Influenza A
    123793902 (NFKBIA)
   05162 Measles
    123793902 (NFKBIA)
   05168 Herpes simplex virus 1 infection
    123793902 (NFKBIA)
   05163 Human cytomegalovirus infection
    123793902 (NFKBIA)
   05167 Kaposi sarcoma-associated herpesvirus infection
    123793902 (NFKBIA)
   05169 Epstein-Barr virus infection
    123793902 (NFKBIA)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    123793902 (NFKBIA)
   05135 Yersinia infection
    123793902 (NFKBIA)
   05134 Legionellosis
    123793902 (NFKBIA)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    123793902 (NFKBIA)
   05140 Leishmaniasis
    123793902 (NFKBIA)
   05142 Chagas disease
    123793902 (NFKBIA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123793902 (NFKBIA)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    123793902 (NFKBIA)
   04931 Insulin resistance
    123793902 (NFKBIA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:uar03000]
    123793902 (NFKBIA)
   04131 Membrane trafficking [BR:uar04131]
    123793902 (NFKBIA)
Transcription factors [BR:uar03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   RHR (Rel homology region) Ankyrin only
    123793902 (NFKBIA)
Membrane trafficking [BR:uar04131]
 Autophagy
  Chaperone mediated autophagy (CMA)
   Selective cargos
    123793902 (NFKBIA)
SSDB
Motif
Pfam: Ank_2 Ank Ank_3 Ank_5 Ank_4 ANK_LRRK2
Other DBs
NCBI-GeneID: 123793902
NCBI-ProteinID: XP_045655916
UniProt: A0A452SDS0
LinkDB
Position
Unknown
AA seq 314 aa
MFQPAEHAQDWAMEGPRDALKKERLLDDRHDSGLDSMKDEDYEQLVKELREIRLEPQEAP
RGAEPWKQQLTEDGDSFLHLAIIHEEKALTMEVIRQVKGDLAFLNFQNNLQQTPLHLAVI
TNQPEIAEALLEAGCDPELRDFRGNTPLHLACEQGCLASVGVLTQTCRTQHLYSILQATN
YNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNGRTALHLAVDLQNSDLVSLLLKCG
ADVNRVTYQGYSPYQLTWGRPSTRIQQQLGQLTLENLQMLPESEDEESYDTESEFTEDEL
PYDDCVLGGQRLTL
NT seq 945 nt   +upstreamnt  +downstreamnt
atgttccagcccgccgagcacgcccaggactgggccatggagggtccgcgggacgcgctc
aagaaggagcggctgctggacgaccgccacgacagcggcctggactccatgaaggacgag
gactacgagcagttggtgaaggagctgcgggagatccgcctcgagccgcaggaggcgccg
cggggcgccgagccctggaagcagcagctcaccgaggacggagactcgttcctgcacttg
gccatcatccatgaagagaaggcactgaccatggaagtgatccgccaagtgaagggcgac
ctggccttcctcaacttccagaacaacctgcagcagactccactccacttggctgtgatc
accaaccaaccagaaatcgctgaggcacttctggaagctggctgtgatcctgagctccga
gactttcgaggaaatacccccctacaccttgcctgtgagcaaggctgcctcgccagtgtg
ggagtcctgactcagacctgcaggacccagcacctctactccatcctccaggccaccaac
tacaatggtcacacgtgtctacatttggcctctatccatggttacttgggcatcgtggag
cttttggtgtctttgggtgctgatgtcaatgctcaggagccctgtaatggtcgaacagcc
ctccatcttgcagtggacctgcagaattctgacctcgtgtcactcttgttgaagtgcggg
gctgacgtcaaccgagtcacctaccagggctactccccataccagctcacctggggccgc
ccaagcacgcggatacagcagcagctgggccagctgaccctagaaaaccttcagatgctg
ccggagagtgaggatgaggagagctacgacacggagtcagagttcacggaagacgagcta
ccctatgatgactgtgtgcttggaggccagcgcctgacgttatga

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