KEGG   Ursus americanus (American black bear): 123794834
Entry
123794834         CDS       T07931                                 
Symbol
IRAK4
Name
(RefSeq) interleukin-1 receptor-associated kinase 4 isoform X1
  KO
K04733  interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
Organism
uar  Ursus americanus (American black bear)
Pathway
uar04010  MAPK signaling pathway
uar04064  NF-kappa B signaling pathway
uar04620  Toll-like receptor signaling pathway
uar04621  NOD-like receptor signaling pathway
uar04722  Neurotrophin signaling pathway
uar04936  Alcoholic liver disease
uar05132  Salmonella infection
uar05133  Pertussis
uar05135  Yersinia infection
uar05140  Leishmaniasis
uar05142  Chagas disease
uar05145  Toxoplasmosis
uar05152  Tuberculosis
uar05161  Hepatitis B
uar05162  Measles
uar05164  Influenza A
uar05168  Herpes simplex virus 1 infection
uar05169  Epstein-Barr virus infection
uar05170  Human immunodeficiency virus 1 infection
uar05171  Coronavirus disease - COVID-19
uar05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:uar00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123794834 (IRAK4)
   04064 NF-kappa B signaling pathway
    123794834 (IRAK4)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    123794834 (IRAK4)
   04621 NOD-like receptor signaling pathway
    123794834 (IRAK4)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    123794834 (IRAK4)
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    123794834 (IRAK4)
   05161 Hepatitis B
    123794834 (IRAK4)
   05171 Coronavirus disease - COVID-19
    123794834 (IRAK4)
   05164 Influenza A
    123794834 (IRAK4)
   05162 Measles
    123794834 (IRAK4)
   05168 Herpes simplex virus 1 infection
    123794834 (IRAK4)
   05169 Epstein-Barr virus infection
    123794834 (IRAK4)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    123794834 (IRAK4)
   05135 Yersinia infection
    123794834 (IRAK4)
   05133 Pertussis
    123794834 (IRAK4)
   05152 Tuberculosis
    123794834 (IRAK4)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    123794834 (IRAK4)
   05140 Leishmaniasis
    123794834 (IRAK4)
   05142 Chagas disease
    123794834 (IRAK4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123794834 (IRAK4)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    123794834 (IRAK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:uar01001]
    123794834 (IRAK4)
Enzymes [BR:uar01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     123794834 (IRAK4)
Protein kinases [BR:uar01001]
 Serine/threonine kinases: TKL group
  IRAK family
   123794834 (IRAK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_fungal Death Haspin_kinase
Other DBs
NCBI-GeneID: 123794834
NCBI-ProteinID: XP_045657195
UniProt: A0A452SR13
LinkDB
Position
Unknown
AA seq 460 aa
MNKPITSSTYVRCLNVGLIRKLSDFIDPQEGWKKLAVAIKKPSGDDRYNQFHIRRFEALL
QTGKSPTCELLFDWGTTNCTVGDLVHLLIQNEFFAPASLLLPDAVPKTVHTLPSKEAVTV
QQKHVPLHGKDRTFVLPVQNIEQNCMPPDSSSPENTSLEGSDTRFHSFSFYELKNVTNNF
DERPISLGGNKMGEGGFGVVYKGYVNNKTVAVKKLVAMVDISTEELKQQFDQEIKVMAKC
QHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDDTPPLSWHMRCKIAQGAANGIS
FLHENHHIHRDIKSANILLDEDFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEAL
RGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDTKMND
TDPTSIETMYSVASQCLHEKKNKRPDIKKVQQLLQDMTTS
NT seq 1383 nt   +upstreamnt  +downstreamnt
atgaacaaacccataacatcttcaacatatgtgcgctgcctcaatgttggactaattagg
aagctgtcagattttattgatcctcaagaaggatggaagaagttagcagtagctattaaa
aaaccatctggtgatgatagatacaatcagtttcacataaggagatttgaagcattactt
caaactggaaaaagtcccacttgtgaattgctgtttgactggggcaccacaaattgcaca
gttggtgatcttgtgcatcttttgattcaaaatgagttttttgccccagcaagtctgttg
ctaccagatgctgttcccaaaacggttcatacactaccttctaaagaagctgtaacagtt
cagcagaagcatgtgcctctccatggcaaagacaggacatttgtgttacctgtgcagaat
attgaacaaaactgtatgccacctgactcctcaagtccagaaaatacaagtttagaaggt
agtgatacacgttttcacagtttttcattttatgaactgaagaatgtcacaaataacttt
gatgagagacccatttctcttggtggcaacaagatgggagagggaggatttggagttgta
tataaaggctacgtgaacaacaaaactgtagcagtgaagaagcttgtagcaatggttgac
attagtactgaagaactgaaacagcagtttgatcaagaaataaaagttatggcaaagtgt
caacatgagaacttagtagaactgcttggtttctcaagtgatggagatgacctctgctta
gtgtatgtttatatgcccaatggctcattactagacaggctgtcttgcttggatgatact
ccaccactttcttggcacatgagatgcaagattgctcaaggtgcagctaatggcatcagt
tttttacatgaaaaccatcatattcatagagacattaaaagtgcaaatatcttactagat
gaagactttacagccaaaatatctgactttgggcttgcacgggcttctgagaagtttgcc
cagacagtcatgactagcagaattgtgggaacaacagcttatatggcacctgaggcttta
cgaggagagataacacccaaatctgacatctacagctttggtgtggttttattagaaata
ataactggacttccagctgtggatgaacaccgtgagcctcagttattgctagatattaaa
gaagaaattgaagatgaagaaaagacaattgaagactatattgatacaaagatgaatgac
actgatcctacttccattgaaactatgtactctgttgctagtcaatgcttgcatgaaaag
aaaaataagagaccagatattaagaaggttcaacagctgctgcaagacatgacaacttct
taa

DBGET integrated database retrieval system