Ursus americanus (American black bear): 123795003
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Entry
123795003 CDS
T07931
Symbol
NOTCH2
Name
(RefSeq) neurogenic locus notch homolog protein 2
KO
K20994
Notch 2
Organism
uar
Ursus americanus (American black bear)
Pathway
uar01522
Endocrine resistance
uar04330
Notch signaling pathway
uar04658
Th1 and Th2 cell differentiation
uar04919
Thyroid hormone signaling pathway
uar05165
Human papillomavirus infection
uar05200
Pathways in cancer
uar05206
MicroRNAs in cancer
uar05207
Chemical carcinogenesis - receptor activation
uar05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
123795003 (NOTCH2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
123795003 (NOTCH2)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
123795003 (NOTCH2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123795003 (NOTCH2)
05206 MicroRNAs in cancer
123795003 (NOTCH2)
05207 Chemical carcinogenesis - receptor activation
123795003 (NOTCH2)
09162 Cancer: specific types
05224 Breast cancer
123795003 (NOTCH2)
09172 Infectious disease: viral
05165 Human papillomavirus infection
123795003 (NOTCH2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
123795003 (NOTCH2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
EGF
hEGF
EGF_TEN
EGF_CA
Ank_2
Ank
Notch
NOD
NODP
Ank_5
Ank_3
EGF_2
Ank_4
EGF_3
EGF_Teneurin
JAG1-like_EGF2
EGF_DL_JAG
Elf-1_N
cEGF
Motif
Other DBs
NCBI-GeneID:
123795003
NCBI-ProteinID:
XP_045657336
LinkDB
All DBs
Position
Unknown
AA seq
2109 aa
AA seq
DB search
MCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMA
NSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLC
MPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCL
NGAKCIDHPNGYECQCATGFTGVLCDENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGA
ICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGINCEINFDDCASNPCVHGVCMDG
INRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINDVNGFRCLCPEGPHHPSCYSQVN
ECLSSPCIHGNCTGGLSGYKCLCDAGWVGINCEVDRNECLSNPCQNGGTCDNLVNGYRCT
CKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCQCVLPYTGKNCQTVLAPCSPNPC
ENAAVCKEAPNFESYTCLCAPGWQGQRCTVDIDECVSKPCMNHGLCHNTQGSYMCECPPG
FSGMDCEEDIDDCLANPCQNGGSCVDGVNTFSCLCHPGFIGDKCQTDMNECLSEPCKNGG
TCSDYVNSYTCKCQSGFDGVHCENNIDECTESSCFNGGTCIDGINSFSCLCPVGFTGPFC
LHEINECNSHPCLNEGICVDGLGTYRCTCPLGYTGKNCQTLVNLCSRSPCKNKGTCIQEK
AESRCLCPSGWAGAYCDVPNVSCEVAAFHRGVSTDHLCQHSGVCINAGNSHHCQCPLGYT
GSYCEEQLDECSSNPCQHGATCRDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTC
VDLVNHFKCSCPPGTRGLLCEENIDDCAGGPRCLNGGQCVDRIGGYSCRCLPGFAGERCE
GDINECLSNPCSSEGSLDCIQLTNDYLCVCRNAFTGRHCETFIDVCPQMPCLNGGTCAVA
SNMPDGFICRCPPGFSGARCQSSCGQVKCRRGEQCVHTASGPRCFCPNPQDCESGCASSP
CQHGGSCYPQRQPPYYSCQCSPPFWGSHCELYTAPTSTPPATCLSQYCADKARDGVCDEA
CNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTAECLFDNFECQGNSKT
CKYDKYCADHFKDNHCDQGCNSEECGWDGLDCAADRPENLAEGTLVIVVLMPPEQLLQDA
RSFLRALGTLLHTNLHIKRDSQGALMVYPYYGEKSAAMKKQKMTRRSLPGDQEQEVAGSK
VFLEIDNRQCVQDSDQCFKNTDAAAALLASHAIQGTLSYPLVSVVSESLTPKRTQLLYLL
AVAVVIILFIILLGVIMAKRKRKHGSLWLPEGFTLRRDSSNHKRREPVGQDAVGLKNLSV
QVSEANLIGSGTSEHWVDDEGPQPKKAKAEDEALLSEEDDAIDRRPWTQQHLEAADIRRT
PSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDMSDEDEDGEDSSANIITDL
VYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAADA
QGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSALH
WAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITDHM
DRLPRDVARDRMHHDIVRLLDEYNVTPSPPGTVLTSALSPVICGPNRSFLSLKHTPMGKK
PRRPNTKSTMPTSLPNLAKEGKDAKGSRRKKSLSDKGQLSESSVTLSPVDSLESPHTYVS
DTTSSPMITSPGILQASPNPMLATAAPPAPVHAQHALSFSNLHEMQPLAHGASTVLPSVS
QLLSHHHIVPPGSSSAGSLSRLHPVTVPADWMNRMEMNETQYNEMFGMVLAPAEGTHPGI
APQSRPPEGKHITTPREPLPPIVTFQLIPKGNIAQPAGTPQPQSNCPPPVAGPVPTMYQI
PEMARLPSMAFPTAMMPQQDGQVAQTILPAYHPFPASVGKYPTPPSQHSYASSNAAERTP
SHSGHLQGEHPYLTPSPESPDQWSSSSPHSASDWSDVTTSPTPGGAGGGQRGPGTHMSEP
PRSNMQVYA
NT seq
6330 nt
NT seq
+upstream
nt +downstream
nt
atgtgcccagaaggaaaagcaggtctcttatgtcatctggatgatgcatgcatcagcaat
ccttgccacaagggggcactgtgtgataccaaccccctgaatgggcagtatatttgcact
tgcccccaaggctacaaaggggctgactgcacagaagatgtggatgagtgtgccatggcc
aatagcaatccttgtgagcacgcaggaaaatgtgtgaacacagatggtgccttccactgt
gaatgtctgaagggctatgcagggcctcgttgtgagatggacatcaatgagtgccattcc
gacccctgccagaacgatgcaacctgtctggataagattggaggcttcacgtgtctgtgc
atgccaggtttcaaaggtgtgcattgtgaattggagataaacgaatgtcagagcaaccct
tgtgtgaacaatggtcagtgtgtggataaagtcaatcgcttccagtgtctgtgtccgcct
ggtttcactgggccagtttgccagattgatattgatgactgttccagtactccatgtctg
aatggggcaaagtgtattgatcacccaaatggctatgaatgccagtgtgccacaggattc
actggtgtgttgtgtgatgagaacatcgacaactgtgaccctgatccttgccaccacggc
cagtgtcaggatgggattgattcctacacctgcatctgcaacccagggtacatgggtgcc
atctgcagtgaccagatagatgagtgttacagcagcccctgcctgaatgacggccgctgc
atcgacctggtgaatggctaccagtgcaattgccagcccggcacatcaggtattaattgt
gaaatcaattttgatgactgtgcaagtaacccttgtgtccatggagtctgtatggatggc
attaatcgttacagttgtgtctgctcaccaggattcacagggcagagatgtaacattgac
attgatgagtgtgcctccaatccctgtcgcaagggtgcaacgtgcatcaacgatgtgaat
ggtttccgctgtctgtgccctgagggtccccatcaccccagctgctactcacaggtgaac
gagtgcctgagcagcccctgcatccatggaaactgtactgggggcctcagtggatacaag
tgcctctgtgatgcaggctgggttggcatcaactgcgaagtggacagaaatgaatgtctt
tctaacccatgccagaatggaggaacttgtgacaatctggtgaatggatacaggtgtact
tgcaagaagggctttaaaggctataactgtcaggtgaatattgatgaatgtgcttcaaat
ccgtgtctgaaccaaggaacctgctttgatgacataagtggctatacttgccagtgtgtg
ctgccatacacaggcaagaattgtcagacagtgttggctccctgttccccaaacccgtgt
gagaatgctgctgtttgcaaagaggcaccaaattttgagagttacacctgcctgtgtgcc
cctggctggcaaggtcagcggtgtacagttgacattgatgagtgtgtctccaagccctgc
atgaaccacggtctctgccataacacccagggcagctatatgtgtgagtgtcctccaggc
ttcagtggtatggactgtgaggaggacatcgatgactgccttgccaatccttgccagaat
ggaggttcctgtgtagatggagtgaatactttctcctgcctgtgccatcctggctttatt
ggggataagtgtcagacagacatgaatgagtgtctgagtgaaccctgtaagaatggaggg
acctgctctgactatgtcaacagttacacttgcaagtgccagtcgggatttgatggagtc
cactgtgagaacaacattgacgagtgcactgagagctcctgtttcaatggtggcacctgt
atcgacgggattaactccttctcttgcttgtgccctgtgggcttcactggccccttctgc
ctccatgagatcaatgaatgcaactctcatccatgcctaaatgaaggaatatgtgtcgat
ggcctgggtacttaccgctgcacctgccccttgggctacactgggaaaaactgtcagacc
ctggtgaacctctgtagtcggtctccatgtaagaacaaaggtacctgcattcaggaaaaa
gcagagtcccggtgcctgtgtccatccggatgggctggtgcttactgtgatgtgcccaat
gtatcctgtgaggtggcggccttccacagaggggtgtccactgaccacctgtgccagcac
tccggcgtctgcatcaatgctggcaactcacatcactgccagtgccccctgggctacact
gggagctactgtgaggagcagcttgatgagtgctcatccaatccctgccagcacggagcc
acctgcagggacttcatcggcgggtacagatgtgagtgtgtcccaggctatcagggcgtc
aattgcgagtatgaagtagatgagtgccagaatcagccatgccagaacgggggcacctgt
gtcgatcttgtgaaccacttcaaatgctcctgtccaccaggcactcgaggcctgctttgt
gaagagaacatcgatgactgtgccgggggcccccgctgccttaacggtggtcagtgtgtg
gataggatcgggggctacagctgtcgctgcttgcctggttttgccggagagcggtgtgaa
ggggacatcaacgagtgcctctcgaacccctgcagctctgagggcagcctggactgcatc
cagctaaccaacgactacctgtgtgtctgccgcaacgccttcactggtcgtcactgtgaa
actttcattgatgtgtgtccccagatgccttgcctgaatggggggacttgtgctgtggcc
agcaacatgcctgatggtttcatttgtcgttgtcccccgggattctccggggcaagatgc
cagagcagctgtggacaagtgaagtgcaggagaggggagcagtgtgtgcacacggcctcg
ggacctcgctgcttctgtcccaacccccaggactgcgaatcaggctgtgccagtagcccc
tgccagcatgggggtagctgctatcctcaacgccagcctccttactactcttgccagtgt
tctccaccattctggggcagccactgtgaactttacacggcccccaccagcacccctcct
gccacgtgcctgagccagtactgtgccgacaaagctcgggatggcgtctgcgatgaggcc
tgcaatagccatgcctgccagtgggatgggggtgactgttccctgaccatggaaaacccc
tgggccaactgctcttccccacttccctgctgggattacatcaacaaccagtgcgatgag
ctgtgcaacacagccgagtgcctttttgacaattttgagtgccaggggaacagcaagacg
tgcaagtatgacaaatactgtgcagaccacttcaaagacaaccattgtgaccagggatgc
aacagtgaggagtgtggctgggacgggctggactgtgctgctgaccggccagagaacctg
gcagaggggaccctggttatagtggtgctcatgcccccagagcagctgctccaggacgcc
cgcagcttcctgcgggcgctgggcaccctgctccataccaacctgcacattaaacgggac
tcgcagggggcactcatggtctacccctattatggtgagaagtcagctgccatgaagaag
cagaagatgactcgcaggtcccttcctggtgatcaagagcaggaggtggctggctctaag
gtatttctggaaattgacaaccgccagtgtgttcaagattcagaccagtgtttcaagaac
acagatgcagcggcagctcttctggcttctcatgccatccaggggaccttgtcctaccct
cttgtgtctgtcgtcagtgaatctctgactccaaaacgcactcagcttctctatctactt
gctgtggctgtcgtcattatcctgtttattatcctgctgggagttatcatggcgaaacga
aagcgcaagcatggctccctctggctgcctgaaggtttcacccttcgccgagactccagc
aatcacaagcgtcgtgagccagtgggacaggatgccgtggggctgaaaaatctctcagtg
caagtctcagaagctaacctaattggttctggaacaagtgaacattgggttgatgatgaa
gggccccagccaaagaaagccaaggctgaagatgaggctttgctctcagaggaagatgat
gccattgatcgacgtccatggacacagcagcaccttgaggctgcagatatccgcaggaca
ccatcgctggcgctcactcctccacaggcggagcaggaggtagacgtgctggacgtgaat
gtccgtggcccagatgggtgcaccccactgatgctggcttctctccgaggaggcagctca
gatatgagcgatgaagatgaagatggagaggactcttctgccaacatcatcacagacttg
gtctaccagggtgccagcctgcaggcccagacagaccggacaggtgaaatggcactgcac
cttgcggcccgctactcgagggctgatgctgccaagcgtctcctggatgcaggtgcggac
gccaacgcgcaggacaacatgggccgctgccctctccatgctgcagtggcagctgacgcc
cagggggtcttccagattctgatccgcaaccgagtaactgatctggatgccaggatgaac
gatggcactacaccgctgatcctggccgcccgcctagctgtggagggaatggtggcagaa
ctgatcaactgccaagcagatgtgaacgcagtggatgaccatgggaaatctgctcttcac
tgggcagctgctgtcaataacgtggaggcaacccttttgctgttgaaaaacggggccaac
cgagacatgcaggacaacaaggaagagacacctctgtttcttgctgcccgggagggaagc
tatgaagcagccaagatcctgttagaccattttgccaatcgggacatcacagaccacatg
gatcgtcttccccgggatgtggctcgagaccgcatgcaccatgacattgtgcgcctcctg
gatgagtacaatgtgacaccaagccctccaggcactgtgctgacttctgccctctcacct
gtgatctgtgggcccaacagatctttcctcagcctaaagcataccccaatgggcaagaag
cctagacggcccaataccaagagtaccatgcccactagcctccctaaccttgccaaggag
ggcaaggatgccaagggtagtaggaggaaaaagtctctgagtgacaagggtcagctgtct
gagagctcagtgactttatcccccgttgattccttagaatctcctcacacatatgtttct
gacaccacatcctctccaatgattacatcccctggaatcttacaggcctcgcccaaccct
atgttggccactgctgccccccctgccccagtccatgcccagcatgcactgtctttctct
aacctgcatgaaatgcagcctttggctcatggggccagcactgtgcttccctcagtgagc
cagctgctgtcccaccaccacattgtccccccaggcagtagcagtgcgggaagcttgagt
aggctccatcctgtcactgttccggcagattggatgaaccgcatggagatgaatgagacc
cagtacaatgagatgtttggtatggttctggctccagctgagggcacgcaccctggcata
gctccccagagcaggccacctgaagggaagcacataactacccctcgggagcctttgccc
cccattgtgactttccagctaatccccaaaggcaatattgcccaaccggctgggactccc
cagcctcagtccaactgccctcctcctgttgcaggccctgtgcccaccatgtaccagatt
ccagaaatggctcgtttgcccagtatggctttccccactgccatgatgccccagcaggat
gggcaggttgctcagaccattctccctgcctatcatccttttccagcctctgtgggcaag
taccctacaccaccttcacagcatagttatgcttcctcaaatgctgctgagcgaacaccc
agtcacagtggtcacctgcagggtgaacatccctacctgacaccatccccagagtctcct
gaccagtggtcaagttcatcaccccactctgcttctgactggtcagatgtgaccaccagc
cctacccctgggggtgctggaggaggtcagcggggacctggaacacacatgtctgagcca
ccacgcagcaacatgcaggtttatgcatga
DBGET
integrated database retrieval system
