KEGG   Ursus americanus (American black bear): 123795272
Entry
123795272         CDS       T07931                                 
Symbol
PRKACB
Name
(RefSeq) cAMP-dependent protein kinase catalytic subunit beta isoform X1
  KO
K04345  protein kinase A [EC:2.7.11.11]
Organism
uar  Ursus americanus (American black bear)
Pathway
uar01522  Endocrine resistance
uar04010  MAPK signaling pathway
uar04014  Ras signaling pathway
uar04020  Calcium signaling pathway
uar04024  cAMP signaling pathway
uar04062  Chemokine signaling pathway
uar04081  Hormone signaling
uar04082  Neuroactive ligand signaling
uar04114  Oocyte meiosis
uar04140  Autophagy - animal
uar04211  Longevity regulating pathway
uar04213  Longevity regulating pathway - multiple species
uar04261  Adrenergic signaling in cardiomyocytes
uar04270  Vascular smooth muscle contraction
uar04310  Wnt signaling pathway
uar04340  Hedgehog signaling pathway
uar04371  Apelin signaling pathway
uar04530  Tight junction
uar04540  Gap junction
uar04611  Platelet activation
uar04713  Circadian entrainment
uar04714  Thermogenesis
uar04720  Long-term potentiation
uar04723  Retrograde endocannabinoid signaling
uar04724  Glutamatergic synapse
uar04725  Cholinergic synapse
uar04726  Serotonergic synapse
uar04727  GABAergic synapse
uar04728  Dopaminergic synapse
uar04740  Olfactory transduction
uar04742  Taste transduction
uar04750  Inflammatory mediator regulation of TRP channels
uar04910  Insulin signaling pathway
uar04911  Insulin secretion
uar04912  GnRH signaling pathway
uar04913  Ovarian steroidogenesis
uar04914  Progesterone-mediated oocyte maturation
uar04915  Estrogen signaling pathway
uar04916  Melanogenesis
uar04918  Thyroid hormone synthesis
uar04919  Thyroid hormone signaling pathway
uar04921  Oxytocin signaling pathway
uar04922  Glucagon signaling pathway
uar04923  Regulation of lipolysis in adipocytes
uar04924  Renin secretion
uar04925  Aldosterone synthesis and secretion
uar04926  Relaxin signaling pathway
uar04927  Cortisol synthesis and secretion
uar04928  Parathyroid hormone synthesis, secretion and action
uar04934  Cushing syndrome
uar04935  Growth hormone synthesis, secretion and action
uar04961  Endocrine and other factor-regulated calcium reabsorption
uar04962  Vasopressin-regulated water reabsorption
uar04970  Salivary secretion
uar04971  Gastric acid secretion
uar04976  Bile secretion
uar05012  Parkinson disease
uar05020  Prion disease
uar05030  Cocaine addiction
uar05031  Amphetamine addiction
uar05032  Morphine addiction
uar05034  Alcoholism
uar05146  Amoebiasis
uar05163  Human cytomegalovirus infection
uar05165  Human papillomavirus infection
uar05166  Human T-cell leukemia virus 1 infection
uar05200  Pathways in cancer
uar05203  Viral carcinogenesis
uar05205  Proteoglycans in cancer
uar05207  Chemical carcinogenesis - receptor activation
uar05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:uar00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123795272 (PRKACB)
   04014 Ras signaling pathway
    123795272 (PRKACB)
   04310 Wnt signaling pathway
    123795272 (PRKACB)
   04340 Hedgehog signaling pathway
    123795272 (PRKACB)
   04371 Apelin signaling pathway
    123795272 (PRKACB)
   04020 Calcium signaling pathway
    123795272 (PRKACB)
   04024 cAMP signaling pathway
    123795272 (PRKACB)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    123795272 (PRKACB)
   04081 Hormone signaling
    123795272 (PRKACB)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    123795272 (PRKACB)
  09143 Cell growth and death
   04114 Oocyte meiosis
    123795272 (PRKACB)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    123795272 (PRKACB)
   04540 Gap junction
    123795272 (PRKACB)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    123795272 (PRKACB)
   04062 Chemokine signaling pathway
    123795272 (PRKACB)
  09152 Endocrine system
   04911 Insulin secretion
    123795272 (PRKACB)
   04910 Insulin signaling pathway
    123795272 (PRKACB)
   04922 Glucagon signaling pathway
    123795272 (PRKACB)
   04923 Regulation of lipolysis in adipocytes
    123795272 (PRKACB)
   04912 GnRH signaling pathway
    123795272 (PRKACB)
   04913 Ovarian steroidogenesis
    123795272 (PRKACB)
   04915 Estrogen signaling pathway
    123795272 (PRKACB)
   04914 Progesterone-mediated oocyte maturation
    123795272 (PRKACB)
   04921 Oxytocin signaling pathway
    123795272 (PRKACB)
   04926 Relaxin signaling pathway
    123795272 (PRKACB)
   04935 Growth hormone synthesis, secretion and action
    123795272 (PRKACB)
   04918 Thyroid hormone synthesis
    123795272 (PRKACB)
   04919 Thyroid hormone signaling pathway
    123795272 (PRKACB)
   04928 Parathyroid hormone synthesis, secretion and action
    123795272 (PRKACB)
   04916 Melanogenesis
    123795272 (PRKACB)
   04924 Renin secretion
    123795272 (PRKACB)
   04925 Aldosterone synthesis and secretion
    123795272 (PRKACB)
   04927 Cortisol synthesis and secretion
    123795272 (PRKACB)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    123795272 (PRKACB)
   04270 Vascular smooth muscle contraction
    123795272 (PRKACB)
  09154 Digestive system
   04970 Salivary secretion
    123795272 (PRKACB)
   04971 Gastric acid secretion
    123795272 (PRKACB)
   04976 Bile secretion
    123795272 (PRKACB)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    123795272 (PRKACB)
   04961 Endocrine and other factor-regulated calcium reabsorption
    123795272 (PRKACB)
  09156 Nervous system
   04724 Glutamatergic synapse
    123795272 (PRKACB)
   04727 GABAergic synapse
    123795272 (PRKACB)
   04725 Cholinergic synapse
    123795272 (PRKACB)
   04728 Dopaminergic synapse
    123795272 (PRKACB)
   04726 Serotonergic synapse
    123795272 (PRKACB)
   04720 Long-term potentiation
    123795272 (PRKACB)
   04723 Retrograde endocannabinoid signaling
    123795272 (PRKACB)
  09157 Sensory system
   04740 Olfactory transduction
    123795272 (PRKACB)
   04742 Taste transduction
    123795272 (PRKACB)
   04750 Inflammatory mediator regulation of TRP channels
    123795272 (PRKACB)
  09149 Aging
   04211 Longevity regulating pathway
    123795272 (PRKACB)
   04213 Longevity regulating pathway - multiple species
    123795272 (PRKACB)
  09159 Environmental adaptation
   04713 Circadian entrainment
    123795272 (PRKACB)
   04714 Thermogenesis
    123795272 (PRKACB)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123795272 (PRKACB)
   05205 Proteoglycans in cancer
    123795272 (PRKACB)
   05207 Chemical carcinogenesis - receptor activation
    123795272 (PRKACB)
   05203 Viral carcinogenesis
    123795272 (PRKACB)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    123795272 (PRKACB)
   05163 Human cytomegalovirus infection
    123795272 (PRKACB)
   05165 Human papillomavirus infection
    123795272 (PRKACB)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    123795272 (PRKACB)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    123795272 (PRKACB)
   05020 Prion disease
    123795272 (PRKACB)
  09165 Substance dependence
   05030 Cocaine addiction
    123795272 (PRKACB)
   05031 Amphetamine addiction
    123795272 (PRKACB)
   05032 Morphine addiction
    123795272 (PRKACB)
   05034 Alcoholism
    123795272 (PRKACB)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    123795272 (PRKACB)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    123795272 (PRKACB)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    123795272 (PRKACB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:uar01001]
    123795272 (PRKACB)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:uar03019]
    123795272 (PRKACB)
   03036 Chromosome and associated proteins [BR:uar03036]
    123795272 (PRKACB)
Enzymes [BR:uar01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     123795272 (PRKACB)
Protein kinases [BR:uar01001]
 Serine/threonine kinases: AGC group
  PKA family
   123795272 (PRKACB)
Messenger RNA biogenesis [BR:uar03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     123795272 (PRKACB)
Chromosome and associated proteins [BR:uar03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    123795272 (PRKACB)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_C
Other DBs
NCBI-GeneID: 123795272
NCBI-ProteinID: XP_045657873
LinkDB
Position
Unknown
AA seq 397 aa
MAAYKELPCNQYTGTTALQKLEGFASRLFHRHSKSTAHDQKTALENDSLHFSEHTALWDR
SMKEFLAKAKEDFLKKWENPAPNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKI
LDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLR
RIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKG
RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG
KVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAP
FIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFCEF
NT seq 1194 nt   +upstreamnt  +downstreamnt
atggcagcttataaagaactaccctgtaaccagtatacaggtacaactgctcttcagaaa
ttggaaggttttgctagccgattatttcatagacattctaaaagtactgcacatgatcag
aaaactgctctggaaaatgacagccttcatttctctgaacatactgctttatgggacaga
tcaatgaaagagtttctagccaaagccaaagaagactttcttaaaaaatgggaaaatcct
gctccgaataatgctggactggaggattttgaaaggaaaaaaacccttggaacaggttca
tttggaagagtcatgttggtgaaacataaagccactgaacagtattatgccatgaagatc
ttagataagcagaaggttgttaaactgaagcaaatagagcataccttgaatgagaaaaga
atattacaggcagtgaattttccttttcttgttcgactggagtactcttttaaggataat
tctaatttatacatggttatggaatatgtccctgggggtgaaatgttttcccatctaaga
agaattggaaggttcagtgaaccccatgcacggttctatgcagctcagatagtgctaaca
ttcgagtacctccattcactagacctcatctacagagatctaaaacctgaaaatctctta
attgaccaccaagggtatatccaggttacagactttgggtttgccaaaagagttaaaggc
agaacttggacattatgtggcactccagaatatttggctccagagataatcctcagcaag
ggctacaataaggcagtggattggtgggcattaggtgtgttaatctatgaaatggcagct
ggctaccccccattctttgcagaccaaccaattcagatttatgaaaagattgtttctgga
aaggtccgattcccatcgcacttcagttcggatctcaaggaccttctaaggaacctgctg
caggtggatttgacgaagcggtttggaaacctgaagaatggtgtgagtgatataaaaact
cacaagtggtttgccaccacagattggattgctatttaccagaggaaggttgaagcacca
ttcataccaaagttcagaggctctggagataccagcaacttcgatgactatgaagaagaa
gatatccgcgtctctataacagaaaaatgtgcaaaagagttttgtgaattttga

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