KEGG   Ursus americanus (American black bear): 123795625
Entry
123795625         CDS       T07931                                 
Name
(RefSeq) glutathione S-transferase theta-2B-like isoform X1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
uar  Ursus americanus (American black bear)
Pathway
uar00480  Glutathione metabolism
uar00980  Metabolism of xenobiotics by cytochrome P450
uar00982  Drug metabolism - cytochrome P450
uar00983  Drug metabolism - other enzymes
uar01100  Metabolic pathways
uar01524  Platinum drug resistance
uar05200  Pathways in cancer
uar05204  Chemical carcinogenesis - DNA adducts
uar05207  Chemical carcinogenesis - receptor activation
uar05208  Chemical carcinogenesis - reactive oxygen species
uar05225  Hepatocellular carcinoma
uar05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:uar00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    123795625
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    123795625
   00982 Drug metabolism - cytochrome P450
    123795625
   00983 Drug metabolism - other enzymes
    123795625
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123795625
   05204 Chemical carcinogenesis - DNA adducts
    123795625
   05207 Chemical carcinogenesis - receptor activation
    123795625
   05208 Chemical carcinogenesis - reactive oxygen species
    123795625
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    123795625
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    123795625
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    123795625
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:uar02000]
    123795625
Enzymes [BR:uar01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     123795625
Transporters [BR:uar02000]
 Other transporters
  Pores ion channels [TC:1]
   123795625
SSDB
Motif
Pfam: GST_C GST_N GST_N_3 GST_N_2 GST_C_2 GST_C_3
Other DBs
NCBI-GeneID: 123795625
NCBI-ProteinID: XP_045658450
LinkDB
Position
Unknown
AA seq 334 aa
MWGSTDDNFAVKTPQLRTEGRPHRKVTVTVLIAILGKACFQGWPSIGPGALAFPSQGEAR
DLPRSLAQATGKAGSCCPEPAVRRVPAAATMGLELYLDMLSQPCRAVSIFAKKNGIPFKL
CTTEVFKGQHLSKEFFQINSLRRVPTLKDGDFILAESSAILIYLSSKYQTADHWYPSDLR
ARARVHEYLGWHADCIRGTFGVPLWTQVMAPLIGVHVPEEKVQRNKTFMDLALQQLEEKF
LGDQAFVAGQQVSLADLMALEELLQPVAVGCDLFEGRPRLAAWRERVEAFLGSDLLQETR
GPILNILEQAVNKKVPTPPPEVHPCMLLRISRIP
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtggggttccactgatgataattttgctgtgaagacaccccagctaaggacggagggt
agaccgcacagaaaagttaccgtaacagtcctgattgctattcttggaaaggcctgcttt
caaggttggccctccataggtccaggagccctggcgtttccaagccagggtgaagcccgg
gacctgccaagatctctggcacaggcgaccggaaaagcaggcagctgctgtcctgaacct
gctgtccgtcgcgtccccgctgccgccacgatgggcctggagctctacctggacatgctg
tcccagccttgccgcgccgtctccatcttcgccaagaagaacggcatccccttcaagctg
tgcaccacggaggtgttcaaagggcagcacctgagcaaggagttctttcagattaatagc
ctgcggagggtgcccaccctcaaggatggcgacttcatcttggctgaaagctctgccatc
ctgatttacctgagctctaagtaccagacggcggaccactggtacccatcggaccttcgg
gcccgggctcgcgtgcacgagtacctgggctggcatgcggactgcatccggggcaccttc
ggcgtgcccttgtggacccaggtgatggcaccgctcattggggtccatgtgcctgaggag
aaggtgcagcgtaacaagaccttcatggacctggcgctgcagcagctggaggagaagttc
ctgggggaccaggcttttgtcgccggccagcaggtgtcgctggccgacctcatggcgctg
gaggagctgctgcagcctgttgctgttggctgtgacctgtttgagggacggccgagactg
gcagcgtggcgtgagcgagtggaggctttcctgggttctgatctgttgcaggagacccgt
ggtcccatcttgaacatcctggagcaggcggtcaacaaaaaagtcccaaccccgccccca
gaagtccatccgtgtatgctgcttcgtatttccaggatcccctga

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