Ursus americanus (American black bear): 123796025
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Entry
123796025 CDS
T07931
Symbol
FGFR2
Name
(RefSeq) fibroblast growth factor receptor 2 isoform X1
KO
K05093
fibroblast growth factor receptor 2 [EC:
2.7.10.1
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar01521
EGFR tyrosine kinase inhibitor resistance
uar04010
MAPK signaling pathway
uar04014
Ras signaling pathway
uar04015
Rap1 signaling pathway
uar04020
Calcium signaling pathway
uar04144
Endocytosis
uar04151
PI3K-Akt signaling pathway
uar04550
Signaling pathways regulating pluripotency of stem cells
uar04810
Regulation of actin cytoskeleton
uar05200
Pathways in cancer
uar05215
Prostate cancer
uar05226
Gastric cancer
uar05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
123796025 (FGFR2)
04014 Ras signaling pathway
123796025 (FGFR2)
04015 Rap1 signaling pathway
123796025 (FGFR2)
04020 Calcium signaling pathway
123796025 (FGFR2)
04151 PI3K-Akt signaling pathway
123796025 (FGFR2)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
123796025 (FGFR2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
123796025 (FGFR2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
123796025 (FGFR2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123796025 (FGFR2)
05230 Central carbon metabolism in cancer
123796025 (FGFR2)
09162 Cancer: specific types
05226 Gastric cancer
123796025 (FGFR2)
05215 Prostate cancer
123796025 (FGFR2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
123796025 (FGFR2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
uar01001
]
123796025 (FGFR2)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
uar04090
]
123796025 (FGFR2)
00536 Glycosaminoglycan binding proteins [BR:
uar00536
]
123796025 (FGFR2)
Enzymes [BR:
uar01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
123796025 (FGFR2)
Protein kinases [BR:
uar01001
]
Receptor tyrosine kinases (RTK)
FGFR family [OT]
123796025 (FGFR2)
CD molecules [BR:
uar04090
]
Proteins
123796025 (FGFR2)
Glycosaminoglycan binding proteins [BR:
uar00536
]
Heparan sulfate / Heparin
Growth factors/receptors
123796025 (FGFR2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
I-set
Ig_3
ig
Ig_2
V-set
Ig_5
C2-set_2
ABC1
V-set_CD47
DUF5527
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
123796025
NCBI-ProteinID:
XP_045659244
LinkDB
All DBs
Position
Unknown
AA seq
860 aa
AA seq
DB search
MGVTSTWRYGRGRGIGTAAAMVSWARFVCLVVVTMATLSLARPSFNLVEDTTLEPEEPPT
KYQISQPEVYVAAPGESLELRCLLRDAATISWTKDGVHLGPNNRTVLIGEYLQIKGATPR
DSGLYACTAARPVDSEAVYFMVNVTDAISSGDDEDDTDGSEDFVSENSNNKRAPYWTNTE
KMEKRLHAVPAANTVKFRCPAGGNPAPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMES
VVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKV
YSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYIC
KVSNYIGQANQSAWLTVLPKQQAPVREKEITASPDYLEIAIYCIGVFLIACMVVTVILCR
MKTTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPM
LAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKEKPKEAVTVAVKML
KDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRAR
RPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNV
MKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL
GGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDR
ILTLTTNEDGTRNLATLSREATPPGACGLCLYIWIRGVNNWKSNRHTCKEFIQLETCNLH
QEKKNVSGADHGVPWATTRP
NT seq
2583 nt
NT seq
+upstream
nt +downstream
nt
atgggagtgacgtccacgtggagatatggaagaggacgggggattggcaccgccgcagcc
atggtcagctgggcccgcttcgtctgcctggtcgtggtcaccatggcaaccttgtccctg
gcccggccctccttcaatttagtggaggataccactttagagccggaggagccgccaacc
aaataccaaatctcccaacctgaagtttacgtggccgcgcccggggagtcgctagagttg
cgctgtctgttgagagatgccgccacgatcagttggactaaggatggggtacacttgggg
cccaacaataggacagtgcttattggggaatacttgcagataaaaggtgccacgcctaga
gactccggcctctatgcttgcacggcggctaggccggtagacagcgaggctgtctacttc
atggtgaatgtcacagatgccatctcatccggagatgacgaggacgacacagatggctcc
gaggattttgtcagtgagaacagtaacaacaagagagcgccgtactggaccaacacagaa
aagatggaaaagcgacttcatgctgtccctgcagccaatactgtcaagtttcgctgtcca
gctggggggaatccagcaccaactatgcgatggctgaagaatggaaaggagtttaagcag
gaacatcgcattggaggctataaggtgcgaaaccagcattggagccttattatggagagc
gtggtcccgtccgacaaaggaaattacacctgtgtggtagagaacgagtacggctccatc
aatcacacataccacctcgatgtcgttgagcgatcgccacaccggcccatcctccaagcg
ggactgccggccaacgcctccaccgtggtcgggggcgacgtggagttcgtctgcaaagtg
tacagcgacgcccagccccacattcagtggatcaaacatgtagaaaagaacggcagcaaa
tacgggcccgacgggctgccttacctcaaggtgctgaagcactcggggataaatagttcc
aatgcagaagtgctggctctgttcaatgtgactgaggcggatgctggggagtatatatgt
aaggtctccaattatatagggcaggccaaccagtctgcctggctcactgtcctgccaaaa
cagcaagctcctgtaagagaaaaggagattacggcttccccagactacctggagatagcc
atttactgcataggggtcttcctgattgcgtgtatggtggtgacggtcatcctgtgccga
atgaagaccacgaccaagaagccagacttcagcagccagccagctgtgcacaagctgacc
aagcgcatccccttgcggagacaggtaacagtttctgccgagtccagctcctccatgaac
tccaacaccccgctggtcaggataaccacgcgcctctcctcaactgcagacacccccatg
ctggcaggggtctccgagtatgaattgccggaagatccaaagtgggagttcccaagagat
aagctgacgctgggcaaacctctgggggaaggttgctttgggcaagtggtcatggctgag
gcggtgggaatcgacaaagagaagcccaaggaagcagtcactgtggcggtgaagatgttg
aaagatgatgccaccgagaaggatctttctgatctggtgtcagagatggagatgatgaag
atgattggaaaacacaaaaatatcataaatctccttggagcctgtactcaggatgggcct
ctctacgtcatcgtggagtatgcctcgaaaggcaacctccgcgaatacctccgagcgcgc
aggccgccggggatggagtactcctatgacattaaccgcgttcccgaggagcagatgacc
ttcaaggacttggtgtcctgcacctaccagctggcgagaggcatggagtacttggcttcc
cagaaatgtattcatcgggatttagcagccagaaatgttttggtcacagaaaacaatgtc
atgaaaatagcagattttggactggccagggatatcaacaatatagactattacaaaaag
accacgaacgggcgacttccagtcaagtggatggccccagaagccctttttgaccgggtg
tacacccatcagagtgacgtttggtccttcggggtgttaatgtgggagatcttcacgtta
gggggctccccctacccagggattccggtggaggaactttttaagctgcttaaggaagga
cacaggatggataagccggccaactgcaccaatgagctatatatgatgatgagggactgt
tggcatgcggtgccctcccagaggccgacattcaaacagctggtagaagacttggatcgg
attctcactctcacaaccaatgaggacggcaccaggaacctagccacactgagcagggag
gccacacctccaggagcttgtgggctctgcttgtatatatggatcagaggagtaaataat
tggaaaagtaatcggcacacgtgtaaagaatttatacagttggaaacttgtaatcttcac
caggagaagaagaatgtttctggggcggaccatggagtgccgtgggccaccacgcgcccg
tga
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