Ursus americanus (American black bear): 123799015 Help Entry 123799015         CDS       T07931                                  Symbol PSEN1 Name (RefSeq) presenilin-1 isoform X1   KO K04505   presenilin 1 [EC:3.4.23.-] Organism uar  Ursus americanus (American black bear) Pathway uar04310   Wnt signaling pathway uar04330   Notch signaling pathway uar04519   Cadherin signaling uar04722   Neurotrophin signaling pathway uar05010   Alzheimer disease uar05022   Pathways of neurodegeneration - multiple diseases uar05165   Human papillomavirus infection Brite KEGG Orthology (KO) [BR:uar00001]  09130 Environmental Information Processing   09132 Signal transduction    04310 Wnt signaling pathway     123799015 (PSEN1)    04330 Notch signaling pathway     123799015 (PSEN1)   09133 Signaling molecules and interaction    04519 Cadherin signaling     123799015 (PSEN1)  09150 Organismal Systems   09156 Nervous system    04722 Neurotrophin signaling pathway     123799015 (PSEN1)  09160 Human Diseases   09172 Infectious disease: viral    05165 Human papillomavirus infection     123799015 (PSEN1)   09164 Neurodegenerative disease    05010 Alzheimer disease     123799015 (PSEN1)    05022 Pathways of neurodegeneration - multiple diseases     123799015 (PSEN1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:uar01002]     123799015 (PSEN1) Peptidases and inhibitors [BR:uar01002]  Aspartic peptidases   Family A22: presenilin family    123799015 (PSEN1) SSDB OrthologParalogGFIT Motif Pfam:  Presenilin Motif Other DBs NCBI-GeneID:  123799015 NCBI-ProteinID:  XP_045663833 UniProt:  A0A452QUG8 LinkDB All DBs Position Unknown AA seq 468 aa AA seqDB search MTELPAPLSYFQNAQMSEDNHLSNTVRSQNDNRERHEHSSERRRRGNPEPLSNGRPQGNS RQVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFT EDTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSF IYLGEVFKTYNVAMDYITVALLIWNFGVVGMIAIHWKGPLRLQQAYLIMISALMALVFIK YLPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMA EGDPEAQRKVPKNSNYNAQSTESGTQDPVTESDDGGFSEEWEAQRDSRLGPHHSTTETRA AVQELSSNILASEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLC LTLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI NT seq 1407 nt NT seq  +upstreamnt  +downstreamnt atgacagagttacctgcccctttgtcctacttccagaatgcacagatgtccgaggacaac cacctgagcaatactgtacgtagccagaatgataatagagaacggcatgagcatagcagc gaaaggcggagacgtggcaaccctgagccattatctaatggacgaccccagggtaactca cggcaggtggtggaacaagatgaagaagaagatgaagagctgacattgaaatatggcgcc aaacatgtgatcatgctctttgtccctgtgactctctgtatggtggtggtcgtggctact atcaaatcagtcagcttctatacccggaaggatggacagctaatctataccccattcacg gaagacacagagaccgtagggcagagagccctgcactctattctgaatgctgctatcatg atcagcgtcatagttgtcatgactattctcctggtggttctgtataaatacaggtgctac aaggtcattcatgcctggcttattatttcatctctgttgttgctgttctttttctcattc atttacttgggggaagtgtttaaaacctacaatgttgccatggactacattactgttgca ctcctgatctggaattttggtgtggtgggaatgattgccattcactggaaaggaccgctg cgactccagcaggcatatctcattatgatcagtgccctcatggccctggtatttatcaag taccttccagaatggacagcgtggctcatcttggctgtgatttcagtatatgatttagtg gctgttttgtgtcccaaaggcccacttcgtatgctggttgaaacagctcaggagagaaat gaaactctctttccagctcttatttactcctcaacaatggtgtggttggtgaatatggca gagggagacccagaagcccaaaggaaggtacccaaaaactccaattataatgcacaaagc accgaaagcgggacccaagatcctgtgacagagagcgatgatggtggtttcagtgaagag tgggaagcccagagggacagtcgcctaggacctcatcattctacgactgagacacgagct gctgtgcaggaactttccagcaacatcctcgccagtgaggacccagaagaaaggggagta aaacttggattaggagatttcattttctacagtgttctggttggtaaagcttctgcaaca gccagcggagactggaacacaaccatagcctgttttgtagccatattaattggtttgtgc cttacattactactgctcgccattttcaagaaagcattgccagctcttccgatctctatc acctttgggcttgttttctactttgccacagattatctcgtacagccctttatggaccag ttagcattccatcaattttatatttag

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