Ursus americanus (American black bear): 123799050 Help Entry 123799050         CDS       T07931                                  Symbol ACTN1 Name (RefSeq) alpha-actinin-1 isoform X1   KO K05699   actinin alpha 1/4 Organism uar  Ursus americanus (American black bear) Pathway uar04510   Focal adhesion uar04517   IgSF CAM signaling uar04518   Integrin signaling uar04519   Cadherin signaling uar04520   Adherens junction uar04530   Tight junction uar04670   Leukocyte transendothelial migration uar04810   Regulation of actin cytoskeleton uar05146   Amoebiasis uar05203   Viral carcinogenesis uar05322   Systemic lupus erythematosus Brite KEGG Orthology (KO) [BR:uar00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04517 IgSF CAM signaling     123799050 (ACTN1)    04518 Integrin signaling     123799050 (ACTN1)    04519 Cadherin signaling     123799050 (ACTN1)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     123799050 (ACTN1)    04520 Adherens junction     123799050 (ACTN1)    04530 Tight junction     123799050 (ACTN1)   09142 Cell motility    04810 Regulation of actin cytoskeleton     123799050 (ACTN1)  09150 Organismal Systems   09151 Immune system    04670 Leukocyte transendothelial migration     123799050 (ACTN1)  09160 Human Diseases   09161 Cancer: overview    05203 Viral carcinogenesis     123799050 (ACTN1)   09174 Infectious disease: parasitic    05146 Amoebiasis     123799050 (ACTN1)   09163 Immune disease    05322 Systemic lupus erythematosus     123799050 (ACTN1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:uar04131]     123799050 (ACTN1)   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:uar04812]     123799050 (ACTN1)    04147 Exosome [BR:uar04147]     123799050 (ACTN1) Membrane trafficking [BR:uar04131]  Exocytosis   Small GTPases and associated proteins    Rab associated proteins     123799050 (ACTN1) Cytoskeleton proteins [BR:uar04812]  Eukaryotic cytoskeleton proteins   Actin filaments / Microfilaments    Actin-binding proteins     Cross-linking proteins      123799050 (ACTN1) Exosome [BR:uar04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    123799050 (ACTN1)   Exosomal proteins of colorectal cancer cells    123799050 (ACTN1)   Exosomal proteins of bladder cancer cells    123799050 (ACTN1) SSDB OrthologParalogGFIT Motif Pfam:  Spectrin CH EFhand_Ca_insen EF-hand_8 EF-hand_1 EF-hand_6 EF-hand_7 EF-hand_5 XisI Uds1 Motif Other DBs NCBI-GeneID:  123799050 NCBI-ProteinID:  XP_045663918 LinkDB All DBs Position Unknown AA seq 914 aa AA seqDB search MDHYDSQQTNDYMQPEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFR DGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNV KMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFC ALIHRHRPELIDYGKLRKDDPLTNLNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMT YVSSFYHAFSGAQKAETAANRICKVLAVNQENEQLMEDYEKLASDLLEWIRRTIPWLENR APENTMHAMQQKLEDFRDYRRLHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRM VSDINNAWGCLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLRQK DYETATLSEIKALLKKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSPNVNARCQKIC DQWDSLGALTQKRREALERTEKLLETIDQLYLEYAKRAAPFNNWMEGAMEDLQDTFIVHT IEEIQGLTTAHEQFKATLPDADKERLAILGIHNEVSKIVQTYHVNMAGTNPYTTITPQEI NGKWDHVRQLVPRRDQALTEEHARQQHNERLRKQFAAQANVIGPWIQTKMEEIGRISIEM HGTLEDQLSHLRQYEKSIVNYKPKIDQLEGDHQLIQEALIFDNKHTNYTMEHIRVGWEQL LTTIARTINEVENQILTRDAKGISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGY DIGNDPQKKTGMMDTDDFRACLISMGYNMGEAEFARIMSIVDPNRLGVVTFQAFIDFMSR ETADTDTADQVMASFKILAGDKNYITVDELRRELPPDQAEYCIARMAPYTGHDAVPGALD YMSFSTALYGESDL NT seq 2745 nt NT seq  +upstreamnt  +downstreamnt atggaccattatgattcccagcaaaccaacgactacatgcagccggaagaggactgggat cgggacctgctcctggacccggcatgggagaagcagcagagaaagacattcacggcctgg tgcaactcccacctgcgcaaggcggggacgcagatcgagaacatcgaggaggacttccgg gacggactgaagctcatgctgctgctggaggtcatctcaggggagcgcttggccaagccg gagagaggcaaaatgagggtgcacaagatctccaacgtcaacaaggccctggatttcata gccagcaagggggtcaagctcgtgtccattggagctgaagaaatcgtggatgggaatgtg aaaatgaccctgggcatgatctggaccatcatcctccgttttgccatccaggacatctct gtggaagagacctctgcgaaggaagggctgctcttgtggtgtcagagaaagacagcccct tacaaaaacgtcaacatccagaacttccacataagctggaaggacggcctcggcttctgt gccttgatccaccgacaccggcctgagctgattgactatgggaagctgcggaaggacgac ccactcacaaatctgaacacagccttcgatgtggccgagaagtacctggacatccccaag atgttggatgcggaagacatcgtcggaaccgcccggccggatgagaaagccatcatgact tacgtgtccagtttctaccatgccttctctggagcccagaaggcggagacagcagccaat cgcatctgcaaggtgttggccgtcaaccaggagaatgagcagctcatggaagactatgag aagctggccagcgatctgttggagtggatccgccgcaccatcccgtggctggagaaccgg gcgccggagaacaccatgcacgccatgcagcagaagctggaggacttccgggactaccgg cgcctgcacaagccgcccaaggtgcaggagaagtgccagctggagatcaacttcaacacg ctgcagaccaagctgcgcctcagcaaccggcccgccttcatgccctccgagggcaggatg gtctcggacatcaacaatgcctggggctgcctagagcaggcggagaagggctacgaggag tggctgctgaacgagatccggaggctggagcggctcgaccacctggcagagaagttccgg cagaaggcctccatccacgaggcctggacggatggcaaagaggctatgctacggcagaag gactatgagaccgccaccctctcggagatcaaggccctgctcaagaagcatgaggccttt gagagcgacctggctgcccaccaggaccgcgtggagcagatcgcagccatcgcgcaggag ctcaatgagctggactattacgactcccccaatgtgaacgcccggtgccagaagatctgt gaccagtgggacagtctgggagccctgacccagaagcggagggaggctctggagcggaca gagaaactgctggagaccattgaccagctgtacttggagtatgccaagcgggccgcaccc ttcaacaactggatggagggggccatggaagatttgcaggacaccttcatcgtgcacacc atcgaggagatccagggactgaccacagcccacgagcagttcaaggccaccctccctgat gccgacaaggagcgcctggccatcctgggtatccataatgaggtgtccaagattgttcag acctaccacgtcaacatggcgggcaccaacccctacacaaccatcactcctcaggagatc aatggcaaatgggaccatgtgcgacagttggtgccacggagggaccaggccctgacggag gagcacgcccgccaacagcacaacgagaggctacgtaagcagttcgcagcccaggccaac gtcatcgggccctggattcagaccaagatggaggagatcggacgcatctccattgagatg cacgggaccctggaggaccagcttagccacctgcggcagtacgagaagagcatcgtcaac tacaagcccaagatcgaccagctggagggcgaccaccagctcatccaggaggcgctcatc ttcgacaacaagcacaccaactacaccatggagcacatccgtgtgggctgggagcagctg ctcaccaccatcgccaggaccatcaacgaagtggagaaccagatcctgacccgagatgcc aagggcatcagccaggagcagatgaatgagttccgggcctccttcaaccactttgaccgg gatcactccggcacgctgggtcccgaggagttcaaagcctgcctcatcagcttgggttat gatattggcaacgacccgcagaagaagacaggcatgatggacacggatgatttccgcgcc tgccttatctccatgggttacaacatgggagaggcagaatttgcccgtatcatgagcatc gtggatcccaaccgcctgggggtagtgacattccaggccttcatcgactttatgtctcgg gagacggccgacacagacacagcagaccaagtcatggcctccttcaagatcctggctggg gacaagaactacatcacggtggacgagctgcgccgagagctgccgcccgaccaggccgag tactgcatcgctcggatggccccctacaccggccacgacgccgtgccgggtgctctggac tacatgtccttctccacggcgctgtacggcgagagcgacctctaa

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