Ursus americanus (American black bear): 123800588
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Entry
123800588 CDS
T07931
Symbol
HIF1A
Name
(RefSeq) hypoxia-inducible factor 1-alpha isoform X1
KO
K08268
hypoxia-inducible factor 1 alpha
Organism
uar
Ursus americanus (American black bear)
Pathway
uar04066
HIF-1 signaling pathway
uar04137
Mitophagy - animal
uar04140
Autophagy - animal
uar04148
Efferocytosis
uar04659
Th17 cell differentiation
uar04919
Thyroid hormone signaling pathway
uar05167
Kaposi sarcoma-associated herpesvirus infection
uar05200
Pathways in cancer
uar05205
Proteoglycans in cancer
uar05208
Chemical carcinogenesis - reactive oxygen species
uar05211
Renal cell carcinoma
uar05230
Central carbon metabolism in cancer
uar05231
Choline metabolism in cancer
uar05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
123800588 (HIF1A)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
123800588 (HIF1A)
04137 Mitophagy - animal
123800588 (HIF1A)
04148 Efferocytosis
123800588 (HIF1A)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
123800588 (HIF1A)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
123800588 (HIF1A)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123800588 (HIF1A)
05205 Proteoglycans in cancer
123800588 (HIF1A)
05208 Chemical carcinogenesis - reactive oxygen species
123800588 (HIF1A)
05230 Central carbon metabolism in cancer
123800588 (HIF1A)
05231 Choline metabolism in cancer
123800588 (HIF1A)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
123800588 (HIF1A)
09162 Cancer: specific types
05211 Renal cell carcinoma
123800588 (HIF1A)
09172 Infectious disease: viral
05167 Kaposi sarcoma-associated herpesvirus infection
123800588 (HIF1A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
uar03000
]
123800588 (HIF1A)
Transcription factors [BR:
uar03000
]
Eukaryotic type
Basic helix-loop-helix (bHLH)
Factors with PAS domain
123800588 (HIF1A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
bHLH_HIF1A
PAS_3
PAS_11
HIF-1a_CTAD
PAS
HIF-1
PAS_9
PAS_4
HLH
Motif
Other DBs
NCBI-GeneID:
123800588
NCBI-ProteinID:
XP_045666312
LinkDB
All DBs
Position
Unknown
AA seq
850 aa
AA seq
DB search
MASLNCSMKSRKMCYPSKGKLTYINFLFFSPPLPLLLNRISSERRKEKSRDAARSRRSKE
SEVFYELAHQLPLPHNVSSHLDKASVMRLTISYLRVRKLLDAGDLDIEDEMKAQMNCFYL
KALDGFVMVLTDDGDMIYISDNVNKYMGLTQFELTGHSVFDFTHPCDHEEMREMLTHRNG
LVKKGKEQNTQRSFFLRMKCTLTSRGRTMNIKSATWKVLHCTGHIHVYDTNSNQSQCGYK
KPPMTCLVLICEPIPHPSNIEIPLDSKTFLSRHSLDMKFSYCDERITELMGYEPEELLGR
SIYEYYHALDSDHLTKTHHDMFTKGQVTTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQ
CIVCVNYVVSGIIQHDLIFSLQQTECVLKPVESSDMKMTQLFTKVESEDTSSLFDKLKKE
PDALTLLAPAAGDTIISLDFGSNDTETDDQQLEEVPLYNDVMLPSSNEKLQNINLAMSPL
PASETPKPLRSSADPALNQEVALKLEPNPESLELSFTMPQIQDQPASPSDGSTRQSSPEP
NSPSEYCFDVDSDMVNEFKLELVEKLFAEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQ
LRSFDQLSPLESSSTSPQSASTITVFQPAQIQEPPVTTATTTATTDELKTVTKDGIEDIK
ILIASPSPIRAPKVTSSATTSPYSDPGSRTASPNRAGEGVIEQTEKSHPRSPNVLSVTLS
QRTTIPEEELNPKILALQNAQRKRKIEHDGSLFQAVGIGTLLQQPDDRAATTSLSWKRVK
GCKSSEQNGMEQKTIILIPSDLACRLLGQSMDESGLPQLTSYDCEVNAPIQGSRNLLQGE
ELLRALDQVN
NT seq
2553 nt
NT seq
+upstream
nt +downstream
nt
atggcatctttaaattgttccatgaaaagcagaaaaatgtgttatccaagcaaaggcaaa
ctaacttatataaattttctctttttctctcctcctcttcctcttttgttaaataggata
agttctgaacgtcgaaaagaaaagtctagagatgcagctagatctcggcgaagtaaggag
tccgaagttttttatgagcttgctcatcagttgccacttccccataacgtgagctcacat
cttgataaggcttctgttatgaggcttaccatcagctatttgcgtgtaaggaaacttctg
gatgctggtgatttagatattgaagatgaaatgaaggcacagatgaattgcttttatttg
aaagccctggatggttttgttatggttcttacagatgatggtgacatgatttacatttct
gataatgtgaacaaatacatgggattaactcagtttgaactaactggacacagtgtgttt
gattttactcatccgtgtgaccatgaggaaatgagagaaatgcttacacacagaaatggc
cttgtgaaaaagggtaaagagcagaatacacagcgaagcttttttctcagaatgaagtgt
accctaactagccgggggagaactatgaacataaagtcagcaacatggaaagtacttcac
tgcacaggccatattcatgtctacgataccaatagtaaccagtcccagtgtgggtataag
aaaccacccatgacgtgcttggtgctgatttgtgaacccattcctcatccatcaaatatt
gaaattcctttagacagcaagacttttctcagtcgtcacagtctggatatgaaattttct
tattgtgatgaaagaattactgaattgatgggatatgagccagaagaacttttgggccgc
tcaatctatgaatattatcatgctttggattctgaccatctgaccaaaactcatcatgat
atgtttactaaaggacaagtcaccacaggacagtacaggatgcttgccaaaagaggtgga
tatgtatgggttgaaactcaagcaactgtcatatataacactaagaactctcagccacag
tgcattgtatgtgtaaattatgttgtgagtggtattattcagcacgacttgattttctcc
cttcaacaaacagaatgtgtcctcaaaccagttgaatcttcagatatgaaaatgactcag
ctattcaccaaagtcgaatcagaagatacaagtagtctttttgataaacttaagaaggaa
cctgatgctttaactttgctggccccagctgctggagacacaatcatatctttagatttt
ggcagcaatgacacagaaactgatgaccaacaacttgaggaagttccattgtataatgat
gtaatgctcccctcatccaacgaaaaattacagaatataaatttggcaatgtctccatta
cctgcttctgaaactccaaagccacttcgaagtagtgctgaccctgcactcaatcaagaa
gttgcattaaaattagagccaaatccagagtcattggaactttcttttactatgccccag
attcaagatcagccagctagtccttctgatggaagcactagacaaagttcacctgagcct
aacagtcccagtgaatattgttttgatgtggatagtgatatggtcaatgaatttaagctg
gaattggtggagaaactttttgctgaagacacagaagcaaagaatccattttctacccag
gacactgatttagacttggagatgttagctccttatatcccaatggatgacgacttccag
ttacgttccttcgatcagttgtcgccactggaaagcagttctacaagccctcaaagtgcg
agcacaattacagtattccagccagctcaaatccaagaacctcctgttaccactgccact
accactgctaccactgatgaattaaaaacagtgacaaaagatggtatagaagacattaaa
atattgattgcatctccatctcctatccgtgcacctaaagtaactagtagtgccacaaca
tcaccatacagtgatcctggaagtcggacagcctcaccgaacagagcaggagaaggagtc
atagaacagacagaaaaatctcatccaagaagccccaacgtgttatctgtcactttgagt
caaagaactaccattcctgaggaagaactaaatccaaagatactagctttgcagaatgct
cagagaaagcgaaaaatagaacatgacggttcactttttcaagcagtaggaattggaacg
ttattacagcagccagacgatcgtgcagctactacatcactttcgtggaaacgcgtaaaa
ggatgcaaatctagtgaacagaatggaatggagcaaaagacaattattttaataccctct
gatttagcgtgtagactgctggggcaatcaatggatgagagtggattaccacaactgacc
agttatgattgtgaagttaatgctcctatacaaggcagcagaaacctactgcagggtgaa
gaattactcagagctttggatcaagttaactga
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