Ursus americanus (American black bear): 123800743 Help Entry 123800743         CDS       T07931                                  Symbol SYNE2 Name (RefSeq) nesprin-2 isoform X1   KO K19346   nesprin-2 Organism uar  Ursus americanus (American black bear) Pathway uar04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:uar00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     123800743 (SYNE2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:uar03036]     123800743 (SYNE2) Chromosome and associated proteins [BR:uar03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     123800743 (SYNE2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  CH Spectrin_SYNE1 KASH Spectrin SYNE1 CAMSAP_CH Motif Other DBs NCBI-GeneID:  123800743 NCBI-ProteinID:  XP_045666541 LinkDB All DBs Position Unknown AA seq 6903 aa AA seqDB search MASSPVPPTEDEQVSLGIDDRHISLQAEQEDTQKKTFTCWINSQLAKHTPPSVVSDLFAD IKKGHVLLDLLEVLSGQQLPRDRGSNTFQCRINIEHALTFLKHRSIKLINIHVTDIIDGN PSIILGLIWTIILHFHIEELARTLSCNYNQPSLDSVSVADSSPTSSPPAKKCSRAQERWQ MSAKKALLLWAQEQCAPCESVSVTDFKSSWRNGMAFLAVIHALRPDLVDMKSVKHRSNKA NLKEAFRIAEQEFKIPKLLEPEDVDVVNPDEKSIMTYVAQFLQYSKDAAEAGEKAQGKMK DAVVWLNLQEQKLRKVRKDSENETYSKKYESLLSFLESFNEEKKPFLDILPIRRNLDELN EDRLQLREAWDGLTYQINVWKTELNHALPSPLHQIEAWLQEIEELIDEDLPASQDYCEAM ALIQEKMTLIKNLMDKCDCHWSTLLAFENRDEQHLPLVPPKKLEEMKGRINNILGKKFIP RLEFHYYKCSVLGLLDEVKLKLDVWNIKYGNKESVELLLEDWHKFIEEKEFLAQLEASFQ KCEEIHKSLAGEYQDISKEYTTVEYNICMYRKNIYNVKSTLQKVLTCWATYVEKLRLLKA CFEETKKEQIKEVPFETLSQWNVEHTALNEVGNFLIQVSTDEVGSSVSKELRRLNKRWRK FITKTQLEMNLPLIKKQDQPNFDIYENIQLSKEGKPTVDFSTSMSVELPENHNQNIKAGE EHEKENEFTGQLQMAEEVENLIGQMEIWEAETESLLELLRPEEGVDASMEEALQHLIAKG SMYEELVSRTEDTLQMDVQNISSRESLQRVLTVGLQTKIQEAKEKVQINMIKLVAVLKNS ADDSPNLDVRLKVEESQKELDSYMTRAEQLLGQKESPSGLISKYKEALIILNSKSLVKYL KAVEELKNTVSEDVKLSLEDKSRGVCAKWESLHHEMSLYIQQLKIDIEKEKLSDTISKLE KQINKEKKLIRRGRTKGLIKEHEACFSEEGSLYQLNHHMDVLRELCEELTSQKSQQEVRR ALKDYEQKIERLRKCASEIRMTLQPTMGGSLKNKETVNTSENGGRGVHSEVPSAESQDQP STEKAMGSIKNFNLESKLKPQQEESSMQKYEKDQNAALSSLQERYDTHRENLELYLENNK FRIISDFSGDEERSSACLQGKLADLQVLKNETDACWKEFEITSLKLEELDSDIKKPFISN MRDRLKEKEREFQMTLNTRMESLETALKIVLPVEKESLLLCGSDLLLHEIAIQEFHLIDA DGIYQNLKNIQDSIAKQIEICNNLEQSGDAAFKGLHPLDLRAAQSIMLKHRTQLEEANHK VQRSKDALRALEEFLASLRTAELSFELVTDLSASDTQVVQENTVTVEDKEREISLMKDQA RHLDKRLKMLGISLNDAEQGDDTCDKLLVALSRKLFETRGCGGQEELTEENKLLETCIFK NNELLKNIQDVYDQISKISLKDPTVPAVKQRKKSLMRLDKDLDEYEEEKKCLQEMVNSLP QFEDGREKPLNQQFQNTALLWESTKASVTECLDQCERVLELLKQYQNFKGVLTALIQKEE NVISLQASYMGKENLKKRIAEIEIVKEEFSEHLEVVDKINQICRNLQFHLNKMRIFEEPP FEKEANIIVDRWLDINEKTEDYYENLGRALALWDKLFNLKNVIDEWTEKVLRKMELNQLA EEEREKLKEELQTHEQKSSEFSKRVAKIQFLLQSSEIPLELQVMESSVLNKIENVKTQLI GESICSALSGNTAELREDLDQAKTQIGMTESLLKALSPSDSLEIFTKLEEIQQQILQQKH SMMLLENQIGCLTPELSELKKQYESVSDLFNTKKSVLQDHFSKLLNDQCKNFNDWFGNIT MNLKECFESSETKKSVEQKLQKLSDFLTLEGRGSKIQQVGTVLNHVKKHLPKAHVKELNS WIINQEIELEKMESVCQARAKELNDCLQELLRLQDDHRNLSKWLTSQEEKWKEMEKSGEK TELFCEAVARKREQFESLAQLNSSLKEYGLTEEEEIIVESTHLIDRYQTFLRQLCEIDEE AKLPPTEDQSFNDLAHDAIHWIAGIKESLMVLNSSEGKMPLEERIQKIKEIILLKPEGDA KIQTIMSQAESSKAPLAPKTLTDIKNEWDNTLHLANTYLSHQEKLLLEGEKYLQSKEDLR LMLTELKKKQEVGFALQHGLQEKKAQLKIYKKFLQKAQDLTSLLKELKSQGSYLLECTKN PSFSERPWLEIKHLHESLLQQLQDSVEKLEGHVQEHHSYQLCVTDLNAALDDISKEFASF SDKPVDQTAVEEKLQKLQELENRLHLQDGTLKKILALAKSIKQNTSSVGQKIIKDDIKSL KCKQKDLENRLESATQETENCLNSILKSTHSTEQREKFTLPGREEEVTPVGQEPTQDSAA LEKFEEDRDTNTNSAVEVVLSKQLSLDIQESMKNTEDEQKVNELQNQPLELDVMLRNEQL KEIEELYAQLEAKKTAIEPLEQTEYLHKAETSALALHDRGHSGQHLDDLLQALITLKKNK ESQYYLLNDFQEHLASVESSVKALLTEKESLKVGPLDSATYLDKIKKFLASVEKEKASLS KMKIEWENLSNCLTDMDKKFLESQIKQLAHSWEQVKQLAQKKYSQQAVEHEELTLLMRKI QDLDISLQQQRQALQLGLNSPEEEEGSARVVAMATELGTIKHRFSVVKGQAEFQMKRIWG EKEKNTLEDAMDNLQKQLEALEPLNIQVENQIKKGEIRNKMKEITLWVKNLLGELTPTIS LLPDDILSQIRKCKVTHDGILDKQQVVESLVEEVKNNIPNLKADESNDLNHLLQDLQSQY QMLVLKSTERSQQLEFKLEERNRFIAAIEKVQLSLQENEALITPEMRAASTEMELEQERV ALTSSQKELLEAQGVIAAHLQEQTNVCKDLSVFERLFLDDQLKNLKTRANRTQRFIQNKC NDVEHKIRFYREFHETGAALQKEVDHIQRSDLLRNQERNEDVKEELYSLKDRITGIQSSI LQALKLKEVFDSVGLNWDCSQLDQLQILVSEKEKELEEKIRQLDVFMAEHGKYQASLSQL KAMDLQIKKRAEGVLGVPHPSPESSLLSAHILEWRIEKAMCLCQEIIKKLNESKAFDDSF KEKEILRIKLYAEENDKLHKILQNGVLKSQPKEMDEKNLQDKLENYLRVLNQIKSQLEQP LLINLDIEHIQKEKENCEAFHEQVQAEMDSMNAVTLMEKQREENSSDTCDMGTKLRDIED LHAQLNTSIDLRIDVLNDAYESMTRYNEAVTRAMGIFTAREAIVASHKIDLDNPEGPLET PGWKQEELQSTIADIQDLTEKLGTISSPEAKQQLQCTLQELVSKDSAIRGAAKVKESEIE RCLENYKCYRKMKEKVCANLSQMEAVLGQSMFPLPASYKEALERLEQSKALGSNLLSTKE ELMKLRQVLRHLRPACTESDDTCLLRTTAALWDKWLSLLETAKEWEIWCEELKWEWKFVS EEIEREAIILDNLQEDLPEISKTKEAATTEELCELQDSLCRYQENVEKQQLLLTLLLHRM RSIQNVPKSLEAIETIPAFQEITSMQERCNKLFQKAQENKELMESEIQERHSFTKEIITL KNLFRQTATSFQNMDLQDHPEKAEQFEELQSIFKKGKLTFENIMEKLRIKYSEMYTLVPA EIESQVEECRKALEDIDEKISNEVLKSSPSYTMSRKIDEINNGLHNVEKMLQQKSKNIEK AQEIQKKMWDELDLWRSRLNELDSEVQDIVEQDPGQAQEWMDNLMIPFQQYQQVSQRAES RTSQLNKATVKMEEYHDLLRNTEAWVENTSRLLANPADYDSSKALSQHASTLQMALEDSE QKHNLLHSIFTDLEDLSIIFETYDLAQSVQELSRQVAALQQKIMESLPQIQRVADDVVAV ETEVKSIEKKVSKIKAILLSKEIFDFSPEEHLKHGEVILENIRPMKKAVAELVSYQVELR WPQTGMKRLPAFQRTNQLLQDVKLLERVTQEQNELLKIIIKQTNECNEDIENLKHILNNY SAEFSHECLSPDQAANLTQVQGDVEGMEKQILSLKQKKENLLVDLKAAILALHQHVQQDQ QAFEPEMPSARAAEEEGEAERDSQWKGNKTGGLSFLPALTEEAEESSLKSENGDKKAEPS SGSWSSLWKPDRDMGEDGASSSSGTIVQEAAEKISTCENPMAQILAPDSLSPSQTEEGAT PPLKAAALGFSDEQGAFEATVEKSRPKPAEILHACKTQVAELELWLHQANVAFEPETLNA DMQQLVEQQLVGCQAMLTQIEHKVASLLESCKDRGPGDSGATQQEAEALSVKLKTVKCNL EKVQIMLQEKYSEDQHSATLKKPSEHQKDLQPDNPSALESVVTERPQFSRHKDFQQQQVL ELKPMEQKDFIKFIEFNAKNMWPQHCQPDKDTTQKSSESSRASSPENDAPGSVLWARGRS GDKWRYLHHGLSAGLGLPFPEQVQPQVATNMSVLPSVSVYNFRYPTTEELRTYTTQLEDL RQEARNLTQENMTEETYINLDKKLFELFLTLSQCLGSVGEMLRTPGLFREDVCAQQVHCE TLALELKKLYLAMGDKKNDLVKAMTWPGRNTSLFPECFDNLQVYLEHTQATAASKSKSLK AGLDYNRSYQNEIKRLYDQLIKNKTSLQQSLNEISGQSIDEQLQKADACTVELQNSESRV ARLRDEGERLHLPYVLLQEVYKLEDVLDSMWGILRARYAELSSPFITESQQDALLRGMAE LVDIGKEKLAHDHLQQTKSKAALQAQIQNHKVFFQKLVADMLLIQTYSNKMLPSLLQKRE TFWAEQIKEVKFLEEKSHQCGIKLQSLLQKWEEFDENYTSLEKDLEILVSTLPSVSLVEE TEERLVERISFYQQIKRNIDEKHARLYQTLNEGKQLVASVSCPELEGQIAKLEEQWLALN KKIDHELHRLQTLLKHLVSYNRDSDQLTKWLESSQQTLNYWKEQSLNVSQDLDTIRSNIN NFFEFSKELDNKSSLKAAVVGTGSQLLHLKAADTATLRASLAQLEQKWTMLITQLPDIQE KLHQLQMEKLPSRKAITEMISWMNNVEHQTADEDTERSLSSASQVRNLLQKYKEFRMEMD YKQWIVDFVNQSLLQLSTCDVESKRYERTEFAEHLGEMNRQWQRVHGTLNRKIQHLEQLL ESITENENKIQILNNWMEAQEERLKTLQKPGSVISVQKMLLDCQDIENQLAIKSKALDEL RQSYLTSESGTMPLLEDTASRIDGLFQKRSSVINQVNELKTSMHSVLQEWKVYDKLYEEV TMMTIRFWYCMEHSKPVVLSLEALRCQVQNLQSLQDEAENSEESWEKLQEVIGKLKDRCP SVAEIIKEKCQETHARWTQVNQDLADQLQKAQSLLQLWKAYNSAHTEAAARLAQQEAKYQ QLENINMSGNNLAEILTPALQDVKELQRDVQKTKEDLLQNSTLLDRLPQLPEASAHVPLS KQLHSLQRASYLEKMLLMKANEFEFVLSQFKDFGDQLESLKGLIVHEEENLDKLNHQEKE ANPDLFLNHVLAMTAQSPDVEHLNEVSLKLPLSDIAVKTLQNVNRRWIRATATALERCSE LQGIGLNEKFLYCCEKWVQLLEKIEETLKVNVADSLPALLEQQKTYEMLEAEVSINQTIA DSYVTQCLQLLDTTEVEKRPEFISKFTKLKDQWQSAAQSIRQRKSDINGLVGQWRYFTTS VEDLLRFLTDTCHLLSAVKSQDCYSLQQTRRLIRELKSKEIHFQRRQTTFELTLEAGEKL LNTANLETEELIEKKIGQLGDKWKDTQLQVGEVMKQLQSNVETWDQCEKKIKELKSRLQV LKAQSRDPLPELHEDLHRQKELIKELEKSLGNWTQNLKELHTLKTDLTQHILVEDVMVLE EQTEHLHRQWEDLCFRVAVRKQEIEDRLNSWIVFNEKNKELCAWLVQMENKVLQTADISI EEMIEKLQKDCMEEINLFSENKLQLKQMGDQLIKASNKTRAAEIEDKLNKVNDRWQHLFD VIGSRVKKLKETFAFIQQLDKNMSNLRTWLARIESELSKPVVYDVCDDQEIQKRLAEQQD LQRDIEQHSAGVESVFNICDVLLHDSDACANETECDSIQQTTRSLDRRWRNICAMSMERR MKIEETWRLWQKFLDDYSRFEDWLKSAERTAAYPNSSEVLYTNAKEELKRFEAFQRQIHE RLTQLELINKQYRRLARENRTDTASRLKQMAHEGNQRWDTLQRRVTAVLRRLRHFTNQRE EFEGTRESILVWLTEMDLQLTNVEHFSESDADDKMRQLNGFQQEITLNTNKIDQLIVFGE QLIQKSEPLDAVLIEDELEELHRYCQEVFGRVSRFHRRLTSHAPGLEEEKEASENETDME DPREIRADSWRKRRASEEPSSPQSLCHLVPPAPGPERSGCETPVSVDSIPLEWDHTGDVG GSSSHEDDEEGPYYSALSDVEIPENPEAYLKMTTKTLKASSGKSLPEDHSWHVPDSPSCP KHRYKQMGGDRNVQTIPSDASTPYKPAYVKLLLPPGTDGGKGGSRVSNGSSRQEDEGLAA LSGQQSGAFDRWELMQAQELHNQLRINQSLQQLNSEITDITTWLKEMEAELEMLKTAEPP SDIREMELRVKRLKEILKAFDTYKALVVSVNMSSKDFLQTESAESSELQGRVGQLGLRWD TAQGAVESWREGLRQSLLQCQDFHELSQDLLLWLASAESRRQKARVTDPDADPQVLLECR EELMQLERELVERQPQVNTLQEISDSLLIKGHGEDYIEAEEKVHVIEKKLRQLLEQVSQD LVSLQGRQNPDPSLPSLDEVDAGEQPPAASVPTPQAKFEAERMTTDKHKTDSRVPGPSSS RPRRSFVSRVIRAALPLQLLLLLLLLLACLLPSSEEDYSCTQANNFARSFYPMLRYTNGP PPT NT seq 20712 nt NT seq  +upstreamnt  +downstreamnt atggcatctagtcctgtgccgcccaccgaggatgaacaggtttccttgggcatcgatgat cgccatatttcactgcaagctgaacaggaagacactcagaagaaaacctttacctgctgg atcaactcacagttggcaaagcacacgcctccctcggttgtatcagacctgtttgcagac attaaaaaggggcatgttctcctagacctgctggaggtactctcggggcaacagttgcct cgagacagaggatctaatacattccagtgtagaatcaatatagagcatgccctgacattc ctgaaacaccgatcaatcaagctaataaatattcatgttactgatattatagatggaaac ccatccattattcttggcctaatttggacaattatactgcactttcatattgaggagctt gcccggactctttcttgcaattacaatcagccttccctggacagtgtgagtgtggccgac tcatctcctacctcaagtcctccagctaagaagtgctccagagcccaagaaagatggcag atgtctgcaaagaaggctcttctcctgtgggctcaggagcagtgtgccccgtgtgagtcc gtcagtgtgacagattttaagtcaagctggagaaatgggatggcttttttggctgtcatt catgccttgcgaccagacctagttgacatgaagagtgtaaagcacaggtccaacaaagcc aatctgaaagaggccttcagaattgcagaacaagaatttaaaatccccaaattgctagaa ccagaagatgtggatgttgtcaatcccgacgaaaagtcaatcatgacctatgtggcacaa tttctacaatattcgaaggatgcagctgaggctggagagaaagctcagggaaagatgaaa gatgctgtggtctggttaaatctgcaagagcaaaaactacggaaagtgcgaaaggattca gaaaatgagacctactctaaaaagtatgaaagtctgctgtcctttttggagtcattcaat gaagaaaaaaagccctttttggacatcctgccgatcagaaggaatctggatgagctgaat gaagatcggttacagttgcgagaagcctgggacggcctcacctaccagattaatgtgtgg aaaacagagctgaatcatgccttgccctcaccgctgcatcaaatcgaagcctggctccag gagatagaggagcttatagacgaagatttgccagcttcccaggattactgcgaagccatg gctctcatacaagagaagatgactttaatcaagaatctgatggataaatgtgattgtcat tggagtactcttctggcatttgaaaatagagacgaacaacatttgcccctggtaccacct aagaaattggaggaaatgaaaggacgaatcaacaacattttggggaaaaaattcattcca cgtctagaatttcattactataagtgctcagttcttggtttgctagatgaagtgaaatta aagttggatgtttggaacatcaaatatgggaacaaagaatctgtggaattgttgctggaa gactggcataaatttattgaagaaaaagagttcctagctcaacttgaagcttcctttcag aaatgtgaagaaatccataagagtttagctggagaatatcaggatattagcaaagaatat accacggtggaatataatatttgtatgtatagaaaaaatatatataatgtgaaatccact ctacaaaaagttctgacatgttgggctacttatgtggaaaaacttcgcttactcaaggct tgttttgaggagacaaagaaggaacagattaaagaggtccccttcgagacactgtcccag tggaatgtggaacatactgctttaaatgaagtggggaatttcctaattcaagtcagtact gatgaagttggatcatctgtttctaaagaactgagaaggctgaataaaagatggagaaaa tttattacaaaaactcaacttgagatgaacctgccacttataaaaaaacaggatcagccc aattttgacatttatgaaaatattcagctatctaaagaaggaaaaccaactgttgatttt tcaacatctatgtcagtagaacttcctgaaaatcataatcagaatataaaggctggggaa gaacatgagaaagaaaatgaattcacagggcaacttcaaatggctgaagaggttgaaaac ctcattggacaaatggaaatctgggaggcagagaccgaatcccttttggagcttctgaga cctgaagagggtgtagatgcctcaatggaagaagctttgcagcatcttattgccaaaggc tctatgtatgaagagcttgtgtctagaactgaagataccttacaaatggatgtacagaat atttcaagccgggagtcacttcaacgtgttctcacggttgggcttcagacaaagattcaa gaagccaaagagaaagttcagatcaatatgataaaattagttgcagtgttaaaaaactca gctgatgattcaccaaacctggatgtcaggctgaaggtggaagagtcacagaaggagctt gactcctacatgacaagggctgagcaattacttggacaaaaagagagcccgagtggacta atttcaaaatataaggaagcgctaataattcttaattctaaaagtctggtcaagtatctg aaagctgttgaagaactgaaaaatactgtatctgaggatgtaaagctgtctttggaagac aagagtagaggtgtttgtgccaagtgggagtctcttcatcatgagatgtctttatatatt caacaactgaaaatagacattgaaaaagagaaactcagtgacactatttcaaaactcgaa aaacaaataaataaagaaaagaagctaattcgtagagggaggaccaagggtctcatcaag gaacatgaggcctgcttttctgaggaaggcagtctgtaccagctaaaccaccacatggac gtcttgcgggagctgtgtgaagagctgacgtcacagaagagtcaacaagaagtgaggaga gcgctcaaagattacgaacaaaagatagaaagacttcggaaatgtgcttccgagattcgt atgacactgcaacccacgatgggaggctcgttgaaaaacaaggagaccgtgaacacatct gagaacggaggaaggggtgtccacagtgaagtgccatctgcagaatcacaggatcagcca tcaactgaaaaggcaatgggatcgattaagaattttaacctggaatccaagttaaagcct caacaggaagaaagctctatgcagaagtatgaaaaggatcagaatgcagccctcagtagt ttacaagaaaggtatgatacgcacagagaaaatcttgagctgtacctggaaaacaacaaa ttcagaattatttctgatttctccggtgacgaggaaaggagtagtgcttgtctgcagggt aaactggcagacctgcaggtcttaaaaaatgaaaccgatgcttgctggaaagagtttgaa atcacctccttgaagttagaagagcttgacagtgacataaagaagccttttataagtaac atgagagacagattaaaggaaaaagaaagagagtttcagatgactcttaataccagaatg gaatctctggagaccgcactgaagatcgtgttacctgtggagaaggagtcacttctactc tgtggctcggacctgcttctccatgaaatagccattcaagaatttcatctcattgatgct gatggcatttatcaaaacctgaagaatatccaagattccatagccaagcagattgaaata tgtaacaacctggaacagtcgggcgacgctgcgttcaagggattacacccacttgatcta cgtgcagcgcagtctattatgctgaagcacagaacacaactcgaagaagcgaaccacaag gtacagaggagcaaagatgccctcagagctctggaggagtttctggcttctctgagaaca gctgaactctcttttgagcttgtaacggacctttcagcctcagatacccaggtagtacaa gaaaacactgtgacggtagaagataaagaaagagaaattagtctgatgaaggaccaggcc agacatttggataaacgtttgaagatgcttggcataagcttgaacgatgctgaacagggt gacgacacctgtgacaaactccttgttgctttgtcgagaaagttgtttgagacacgtggc tgcggcgggcaggaagagctcaccgaagaaaacaaattactagagacttgtattttcaaa aataatgaactcctgaaaaacattcaagacgtgtacgatcaaatcagcaagatcagtctt aaggatcccacggttccagctgtaaaacaacggaaaaaatcactaatgagactggataag gatctagatgaatatgaagaagagaagaaatgcttgcaagagatggttaattctcttcca caatttgaagatggcagagaaaaacctctgaatcaacagttccaaaatacagcacttttg tgggagagtacaaaagcttcggtcactgaatgccttgaccaatgtgaacgagttttggag ctcttaaaacaatatcagaattttaaaggtgtcttgactgctttgattcaaaaagaagag aatgtcatctcccttcaggcttcctacatgggaaaagagaacctgaagaaaaggatagcg gagattgaaattgttaaagaagaatttagtgaacatttagaagttgtagacaagattaac cagatctgcagaaatctacaatttcatctaaataaaatgagaatttttgaagagcctcct tttgagaaagaagctaatattattgtggatagatggcttgatataaatgaaaagacagaa gactactatgaaaatcttggtcgagctctagcattatgggacaaactttttaacttaaaa aatgtcatcgatgagtggactgaaaaggtccttcgaaaaatggaattaaatcaactggct gaagaagaaagagaaaagctgaaggaagagcttcaaacccatgaacaaaaatcttcagag ttctctaaaagagtggctaaaatacagtttctccttcaaagcagtgaaataccccttgaa ttgcaggtcatggagtcctctgttttaaacaagatagaaaatgtaaagacgcagttaata ggagaatccatctgctctgcgcttagtggcaacacagctgagctcagggaggacctcgac caagccaagacccagattggaatgactgagtcgctcttaaaagccctgtctccttccgac agcttagagatcttcactaaactggaggaaatacagcagcaaatcctgcagcaaaagcac agcatgatgttacttgagaatcaaataggttgtctgactcctgaactctctgaattaaaa aagcaatatgaaagcgtcagtgatttatttaataccaaaaaaagtgttttgcaagatcac ttttctaagttattgaatgatcagtgcaagaactttaatgactggtttggcaacattaca atgaaccttaaagagtgttttgaatcttcagaaacaaaaaagagtgtggaacaaaagcta caaaaactttctgatttcttgactcttgaaggaagaggcagtaaaatacagcaggtggga actgtactgaatcatgtgaagaagcacctgcccaaagcacatgttaaggagcttaacagt tggattataaatcaagaaattgaattagaaaaaatggagtccgtttgccaggcacgagca aaggagctcaatgactgcttgcaggagctactgagactccaggatgaccacagaaatctg agcaagtggttgactagtcaagaagagaaatggaaagaaatggaaaaatcaggagagaaa actgagctattttgtgaagccgtagccagaaagagggaacagtttgaatctctggcccag ttgaacagctctttgaaggaatatgggcttactgaagaagaggaaatcatagtggaatca acacatttgattgatagataccagacatttttgagacaattatgtgaaattgatgaagag gctaagttacctcctacagaggaccagagctttaatgatcttgcacatgatgcaattcac tggatagcagggattaaagagtcccttatggttttgaattcatctgaaggcaaaatgccg cttgaggaaagaatccaaaaaataaaggaaatcattttactgaagcctgaaggggacgct aaaatacagaccatcatgagtcaggctgagagcagcaaggctccattggctccaaagacc cttactgatatcaagaacgagtgggacaacacactccatttagccaacacatatctaagc catcaagaaaagcttctacttgaaggagagaagtatttgcaaagtaaggaggatctgaga ttaatgctcacagaactaaaaaagaaacaggaagtgggctttgctctgcagcatggcttg caggagaagaaagctcagttaaaaatttataagaaattccttcagaaagcacaagatttg acatccttgctaaaagagttaaaatctcaaggaagttacctcttagagtgcactaaaaat cccagcttcagtgaaaggccttggctggaaataaagcatctacacgaaagtcttctccaa cagctacaggattctgtggaaaaattggaaggtcatgttcaagaacaccactcataccag ctttgcgtcacagacctgaatgccgcattggatgatatctccaaggaatttgccagtttt tctgataagcctgtggatcaaacagcagttgaggaaaaactgcagaaactgcaggaacta gagaatagactccatttacaagatggcacattaaagaagattttagctttagcaaaatcc atcaagcaaaatacatcttcagtaggacagaagattattaaagatgatataaaatcactt aagtgtaaacaaaaggatttggaaaacagacttgaatctgctacgcaggagacagaaaat tgtctcaatagcattctcaaatcaacacactcaacagaacagagagaaaagtttactctg ccaggcagagaggaggaggtcactcctgttggtcaggagcccactcaggactccgctgcg ctggaaaagtttgaggaagaccgggacacaaacacgaattcagctgtggaagtggttttg tcaaaacaactttctctggatattcaagaaagcatgaaaaacactgaagatgagcagaaa gtcaatgagctgcaaaatcaacctttagaattagatgttatgttaagaaatgaacaatta aaagagatagaggaattatatgcccagttggaagcaaagaaaacagccattgaaccacta gaacaaactgagtatctccataaagcagaaacaagtgccttggctcttcacgatagggga cattcggggcagcacttggacgatctgcttcaggcactaattactttgaagaaaaataag gaaagccaatattatctccttaatgattttcaggaacaccttgcttcagttgaatcctca gtgaaagccttattgacggaaaaggaaagtcttaaagtggggcctctggacagtgccacc tatctggacaaaattaaaaaattcctggcatccgtcgaaaaagagaaagcttccttaagc aagatgaaaatcgaatgggaaaacttatctaactgcctgaccgacatggataagaagttt ttggaaagccagatcaagcagctcgcacacagctgggaacaggtgaaacagctggctcaa aagaagtattctcagcaagcagtagaacatgaggagttgacacttctcatgaggaagatc caagacctggacatctctctgcagcagcagcggcaggctctacagttagggctcaactct cccgaagaagaggaggggagcgctcgcgtagttgccatggccaccgaactcgggaccatc aagcatcgattttccgtggtaaaggggcaagctgaatttcagatgaagaggatctgggga gaaaaagaaaagaatactttggaagatgcaatggataatttgcagaagcaattagaagcc ttggagccgttaaacatccaggtggaaaatcagatcaagaagggcgaaataaggaacaag atgaaagagattaccctgtgggtcaagaacctgctgggtgaactcactcccaccatttcc cttctcccagacgacattctttcacagatcagaaaatgcaaggtgacacacgatggcatc ctggataagcagcaggtggtggagtcattggttgaagaggtcaaaaataacattcctaac cttaaggcagatgagagcaatgatttaaatcacctcctacaggacttacagagtcaatac caaatgctagttttaaaatcgacggaaagatcgcagcaactagaatttaagttggaagaa agaaacaggtttattgcagccatagagaaggtgcagctttcacttcaagagaatgaagca ctgataactcccgagatgagagcagcctctacagagatggaactagagcaggagcgagtt gcgttgacgagttctcagaaggagctcctggaagctcagggtgtcatcgcagcccacctg caggaacaaacaaatgtctgtaaggatctaagtgtgtttgaaagattatttctggatgac caactgaaaaatcttaagacgagagccaacagaactcaaagattcattcagaacaaatgt aatgatgtagaacacaagatacgtttttacagagaattccatgaaacaggagctgcgctt cagaaggaggttgaccacatacagcgcagtgacctgctacgaaatcaagaaagaaatgaa gacgttaaagaggagctctacagtcttaaagaccgaatcactggtattcagtctagtatc ctccaggcactgaaactcaaagaagtgtttgactctgtaggactaaactgggattgttcc cagcttgaccaattacaaatcctagtatctgaaaaagaaaaggaactcgaagaaaaaatt aggcagttggacgtatttatggcagaacatggcaagtatcaagcgtcactaagtcaattg aaggctatggatttgcaaattaagaaaagggctgaaggagtattaggagtgccccatcca tcacccgaaagcagtctgctcagtgctcacattttggagtggagaattgagaaagccatg tgcttgtgtcaagagataataaagaaattaaatgaaagtaaggcctttgatgactccttc aaagagaaagaaatactccgaataaagctgtatgcagaagaaaatgacaagttacacaag attctccaaaacggggtactaaaatcccaaccaaaagagatggatgaaaagaaccttcag gacaaactggaaaattacttacgtgttttgaatcagataaagtctcagttagagcagcct ttacttataaatttggacattgaacatattcaaaaagaaaaggagaattgtgaagcgttt cacgagcaagttcaggcggaaatggatagcatgaacgctgtgacccttatggagaagcaa agagaagaaaattcttctgacacttgtgatatggggacgaaattgcgggacatcgaagac cttcacgcgcagcttaatacaagcattgatttgcgcatagatgttttgaatgatgcttat gaaagtatgacacgctataatgaggcagtcaccagggcgatgggaatctttactgcccgt gaagccattgttgcctcccataaaatagaccttgataacccagaaggaccactggagacg cctggctggaaacaagaggagttgcaatccacaatagcagatatccaggacctcactgag aaactggggactatctccagccctgaagccaaacaacaactccagtgtactctacaggaa ttggtttctaaggattcagccattaggggggcagccaaagtaaaggaaagtgaaatagaa aggtgtcttgagaattacaaatgctatagaaaaatgaaagagaaagtttgcgctaacctc agccaaatggaggcagttcttgggcagtccatgttcccgttgccggcatcttacaaagaa gctttagagcgcttggaacagagcaaggctttggggtcaaatcttctgtcaaccaaagaa gagttaatgaaactacgtcaggtcctcaggcatctgagacccgcgtgcacagagagtgat gacacctgtttgctcagaaccacggcagctctgtgggacaaatggttgagtttgctggag actgctaaagaatgggagatatggtgtgaggaactgaagtgggagtggaaatttgtcagt gaagaaattgaacgagaagcaattattttagataatcttcaagaagatctccctgaaatt tcgaaaacaaaagaggcggccactacagaggagctctgtgagctgcaagactctttatgc cgttaccaagaaaatgtggagaagcagcagctgttactgaccttacttcttcatcgcatg agaagtatccagaatgttcccaaaagcttagaagctatagaaacaattccagcatttcaa gagattacctcgatgcaagaacgatgcaacaagctttttcagaaagctcaagaaaataag gaattgatggagagtgaaatccaagaaagacattctttcacaaaagaaataattactttg aagaatttatttcgacagactgcaacttctttccaaaatatggacttacaagatcaccca gaaaaggcagaacagtttgaggagcttcaaagcatttttaagaaagggaagctaactttc gagaatattatggaaaaactgcgaatcaagtattctgaaatgtacacgctagtccctgca gagattgaatcccaggtggaagagtgcagaaaagctttagaagacatagatgagaagata agcaacgaagttttgaaaagctcaccctcatatacaatgagtagaaaaatagatgaaatt aacaatggcctccacaatgttgaaaagatgttgcagcagaaaagcaaaaatattgagaaa gctcaagaaattcagaagaaaatgtgggacgagctagacctctggcgttccaggctcaat gagctggattccgaagtgcaggacattgttgaacaggatcccggacaggctcaagaatgg atggataacctgatgattcctttccaacaatatcagcaagtctcacagagagcagaatct agaacctcacagctgaataaggccacagtcaagatggaggaatatcacgaccttttgagg aatacagaggcctgggtagaaaacaccagccgtctgctggctaatcctgcggactatgat tcttcgaaggcgctgagtcagcacgccagcacccttcagatggctttggaagattcagaa cagaaacacaatcttttgcattcaattttcacggatctagaagacttgtcaataattttt gaaacctatgatttagcacagtctgtacaagagttaagtcgtcaagtagcagctttacaa caaaaaatcatggaaagccttccacagattcagcgggtggctgatgatgtggttgctgtc gaaactgaagtaaaatcaatagagaaaaaagtttcaaaaatcaaagctatcctcttatca aaagaaatatttgatttttcaccggaagaacatcttaagcatggggaggtcatacttgaa aacatacgtcccatgaagaaagccgttgctgaactcgtgtcttaccaagtggaactgcgg tggccccagacaggaatgaaacgtctgcctgcatttcagcggacaaatcaacttctacaa gatgtaaaactgttggaaagggtgactcaggaacaaaatgaattattaaagatcatcata aaacagaccaacgaatgcaatgaagacatagaaaatttgaagcacatcttaaataattat tcagctgagttctcccatgaatgtctatcaccagaccaagctgccaacctgacacaagta cagggagatgtcgaaggtatggaaaagcagattctgagtttgaagcagaagaaggagaac ctgctggtggacctgaaggcggccatactggcccttcaccagcacgtacagcaagatcag caggcattcgagccagaaatgccgtcagcccgagcagcagaagaggagggagaggctgag agggattctcagtggaaggggaacaaaaccggtggcctgtccttcctgccggcgctcacg gaagaggcggaagagagctccctgaagagcgaaaatggagataagaaagcagagccgtct tctgggtcttggtcttcactctggaagcctgacagggacatgggggaagatggagcatcc tcgtcctctggaaccatcgttcaggaagcagctgagaaaataagcacatgtgaaaatcct atggcacaaattcttgcaccagattcactgagtcccagccaaacagaggagggtgccaca cctcctctcaaggctgccgctctgggcttttccgacgagcaaggagcttttgaggccacg gtggagaaatcgaggcccaagcctgcggaaatcctccatgcctgtaagacccaggtggcc gagctggagctgtggctgcaccaagccaacgtggcattcgagccggaaacattaaatgca gacatgcagcagttggtggaacagcagctggtagggtgccaggctatgctaacacagatc gagcacaaggttgcttctctgctggagagctgcaaagatcgggggccaggagacagtggg gccactcagcaggaggctgaagctctttccgtgaaattaaagactgtgaagtgcaatttg gaaaaagtccagatcatgcttcaggagaaatacagcgaagaccagcattctgccactcta aagaaaccttcggagcatcagaaggatctccaaccagataacccttctgcattggaatct gttgtaaccgaaaggccacagttcagcagacacaaagatttccagcagcaacaggttctg gagttaaagccaatggaacagaaagatttcatcaaattcatcgaatttaatgccaagaac atgtggccccagcattgccaacctgataaagatacaactcagaaatcatctgaaagcagt agggcgtcaagccccgagaacgatgctccaggctctgtcttgtgggctcggggccggagt ggagataagtggcggtacctacatcacggactctcagcaggactcgggctgccgttccct gagcaggtgcagcctcaggttgccacaaatatgagtgttctgcccagtgtgagtgtgtat aacttcagatacccgacaactgaagaactgagaacatacaccacacagctggaagacctg cgtcaggaagcgaggaatctgacccaggaaaacatgacagaagaaacatacataaatttg gataaaaaattatttgagctatttctgaccctcagtcagtgccttggcagtgtgggcgag atgctgcggacacccgggctcttcagagaggatgtctgtgcccagcaggtgcactgcgag acactggctcttgaattgaaaaaactttacttagctatgggtgacaagaagaatgacctt gtgaaagccatgacttggcctgggaggaacaccagcttgtttcctgaatgttttgacaac ctccaagtctacctggagcacacccaggccacagctgcctctaaaagcaagtccctgaaa gctggtctcgactataaccgcagttatcagaatgaaataaagcgactgtatgatcaactt attaagaacaaaacatctttacaacagtctttgaatgaaattagtggccagagtattgat gaacagcttcagaaagcagatgcgtgtacagtggagctgcagaactccgagagccgggtg gcaaggctgagagacgaaggggagaggcttcatttgccttatgttttattgcaagaggtt tacaaattagaggatgtacttgacagcatgtggggaatcctgagagcccggtacgcagaa ctcagcagccctttcatcactgagagccagcaagatgccttgctgcgaggcatggcagag ctagtagatatcgggaaggagaagcttgctcatgaccacttacaacaaaccaagagtaaa gctgccttacaggctcaaatacaaaatcacaaggttttttttcagaagcttgttgctgat atgctgttgatccagacatactccaacaaaatgcttccttctttattgcaaaagagagag acattttgggcagaacaaataaaagaagttaaattcctggaggaaaagtcacaccaatgt ggaataaagctgcagagcttgctacagaaatgggaagaatttgatgaaaactatacatct cttgaaaaggatctggaaattctggtatctacattgccctctgtgagtttggtggaagag acagaggaaagattagtggaaaggatttcattttaccagcaaataaaaagaaacattgat gaaaagcatgcccggctctaccaaactctgaatgaaggcaaacagctggtggcatccgtg agctgtcccgaactagagggccagattgcaaagctagaagagcagtggttggccctgaac aaaaaaatcgaccatgaactgcacagactacaaacacttctcaagcatctggtcagttat aacagagattcggatcagttaaccaaatggttggaatcttctcagcaaactctgaattac tggaaagaacaatccctcaatgtgtctcaggacttggatacaatcagaagcaacataaac aacttttttgagttttcaaaggaactcgacaacaagtcttccttgaaggccgcagtcgtg ggaaccgggagccagcttctccacctgaaagcggccgatacggccacgctgagggcttcc ttagcgcagttggaacaaaaatggacaatgctcataactcaacttccagatattcaagaa aaacttcaccagcttcagatggagaaactgccgtctcgtaaagcaatcacggaaatgatt agctggatgaacaatgtggaacatcagaccgcagatgaggacactgagcgttcactgagt tctgcgtctcaagtgagaaatcttcttcagaagtacaaggagttcagaatggaaatggac tataaacagtggatcgttgattttgttaaccagtcattacttcagttaagcacctgtgat gtagaaagtaagcgctatgagagaacagagtttgcagagcacctgggagagatgaaccgc caatggcagcgggtacatggaaccctaaatagaaagatacagcacttagaacaacttttg gaaagtatcactgagaatgaaaacaaaatacagattttgaacaactggatggaggcacaa gaggagagactgaaaactttacaaaaacctggcagtgtgatctcggtgcagaagatgctc ctggactgtcaggatatagaaaatcaacttgcaattaaatccaaagccctggatgagttg agacaaagttacctgacttcagagagtgggacgatgccactgttagaagacacagcatcc agaattgatgggttatttcaaaaaaggagcagtgttatcaaccaggtcaatgagctcaag acctccatgcactcagttttacaggagtggaaggtttatgataaactgtatgaggaagtg acaatgatgacaatccgattctggtactgcatggagcacagcaagcctgtggttttgtca ttagaagccttaagatgccaggtgcagaaccttcagtctcttcaggatgaagccgagaac agtgaagaaagttgggagaaactgcaggaggtgattggaaaactcaaagatcgctgcccc tcagttgctgagataatcaaagagaaatgccaagagacgcatgccaggtggacccaggta aaccaagacctcgcagaccagttgcagaaggcccagagtctgctgcagctctggaaggcc tataacagtgctcacacggaagccgcagcaaggctggcgcagcaggaagcaaagtaccaa cagcttgaaaacatcaacatgtctggaaacaacctggcagagatcctgaccccagccctg caggatgtaaaggagctgcagcgtgatgtacagaagaccaaagaagaccttctccagaat tccactctcctggatcgacttccgcagctcccggaggccagcgcccacgtgcccctctcc aaacaactgcactccctccagagggcttcttacttggaaaagatgctgctcatgaaggct aatgaatttgagtttgttctgtcacagttcaaggattttggggaccagttggaatcttta aaaggtctcattgtgcatgaagaagagaatttggataaactcaaccatcaagagaaagaa gccaaccctgacttattcctgaaccatgtgctggcaatgacagcccaatcacctgatgtt gaacatttgaatgaagtaagcctcaagctcccacttagtgacatagccgtgaagacattg caaaacgtgaaccggcggtggattcgggccacagcaactgccctggaacgctgcagtgag cttcagggaattggattgaatgaaaagtttctttattgctgtgaaaaatgggtccagctt ttggagaagatagaagagacactcaaggtgaatgttgccgacagcctcccagctctcctg gagcagcagaaaacatacgagatgttagaagctgaagtttctataaaccagacaattgct gattcttatgtcacccagtgcttacaactcttggacacaacggaagtagagaagagaccg gaatttatttcaaagttcacaaaactgaaggaccagtggcagagcgccgcccagagcatc cggcagaggaagagtgacatcaatgggctggtggggcagtggcggtacttcaccacctcc gtggaggacttgctccgcttcctcacggacacctgccacctgctgtctgcagtgaagagc caggactgctacagcctccagcaaaccagaaggctgatccgtgagctgaagagtaaagaa attcattttcagagacggcaaactacctttgaactaaccttagaagctggggaaaagtta ctgaatacagctaacctggaaactgaagagttgattgagaagaaaatcggtcaacttggg gacaagtggaaggacacgcagctccaagtaggagaggtgatgaaacagttgcagagcaac gtagagacctgggaccagtgtgaaaagaaaatcaaggagttgaaaagcaggctgcaagtt ttaaaggcacaaagtagagaccctcttccagaacttcatgaggacctccacagacaaaaa gagctgattaaggaactagaaaagtctttgggcaactggacgcagaacttgaaagaactt cacactctgaagaccgacttaacccagcacattcttgtggaggacgtgatggttttggag gagcaaacagagcatttgcacagacaatgggaggacctctgcttccgagtggctgtccgc aaacaggagattgaagatagactcaattcatggattgtgttcaatgaaaaaaataaagag ttgtgcgcatggctggtgcagatggaaaacaaagtgctccagacggcagatattagtatc gaagaaatgattgagaagttacagaaggactgcatggaagaaataaacttgtttagtgaa aacaagttacagttaaagcagatgggtgaccagttgatcaaggccagcaacaagacaaga gcagctgagatcgaggacaagctcaacaaagtcaacgaccgttggcagcatctctttgac gtcattggatcacgggtgaagaagctgaaggagacctttgcttttattcagcagttagac aaaaacatgagcaaccttcgtacctggttggctcgaattgagtcagagctctctaagcct gtcgtgtatgacgtctgtgacgatcaagagatccagaagaggctcgccgagcagcaggac ctgcagcgagacatcgaacaacacagcgcgggcgtggagtctgtgtttaacatctgtgat gtcctcctgcatgactctgatgcctgtgccaacgagaccgagtgcgactccatccagcag accaccagaagcttggacagacgctggaggaacatctgcgccatgtcgatggaacggcga atgaaaattgaggagacttggcgcctgtggcagaaatttctagatgattactcccgcttc gaggactggctcaagtccgccgagaggacggcagcctatccgaattcctcagaggtgttg tacacgaatgccaaagaagagctgaagaggttcgaggccttccagcggcagatccacgag aggctgacgcagctcgagctcatcaacaagcagtaccggcggctggcgcgcgagaaccgc accgacacggccagcaggctgaagcagatggcgcacgagggcaaccagcgctgggacacc ctccagaggcgggtcacggccgtgctgcggagactcagacatttcaccaaccaaagggag gaattcgaggggaccagggagagcattctggtgtggctcacggagatggacctgcagctg accaacgtggagcacttctcggagagcgacgccgacgacaagatgcgccagctgaacggt ttccagcaggaaattacactgaacaccaacaagatcgatcagctcattgttttcggggag cagctgatccagaagagcgagccgctggacgccgtgctgatcgaggacgagctggaggag ctgcaccggtactgccaggaagtcttcggccgcgtctcccgcttccaccgcaggctcacc tcccacgccccgggcttggaagaagaaaaagaggcctcggagaatgaaacggacatggag gaccccagagagatccgggccgactcctggcgtaaaaggagagcgagcgaggagccctcg tctcctcagtccctttgtcatctggtgcccccggcgccggggcccgagcggtctggctgc gagacccctgtcagcgtggactccatccctctggagtgggatcacacgggggacgtgggg ggctcgtcctcccatgaagatgacgaggaaggcccgtactacagcgcactgtcagatgta gaaatccctgaaaatcctgaggcatatcttaaaatgaccacaaaaactttgaaagcgtct tctggtaaatcccttcctgaagaccactcgtggcatgttcctgacagcccttcctgcccc aagcatcgctacaaacaaatgggaggtgataggaatgtacagaccatcccctcagatgcc agcaccccttataagccagcctatgtaaagctgctgttacccccgggcactgatggtggc aaaggaggctccagagtctcgaacggcagctcacggcaggaagacgaaggcctggccgct ctcagcgggcagcagtcaggtgcctttgacagatgggagctgatgcaagcccaagaactt cacaatcagctcagaataaaccaaagcttgcaacagctgaactctgagatcaccgacatc accacttggctgaaagaaatggaagcagagctagaaatgttgaagacggcagagcctccc tctgatatccgggaaatggagctccgcgtgaagcgactcaaggaaatcttaaaagccttt gacacctacaaggctttagtggtctctgtcaacatgagcagcaaggactttctgcagacc gagagcgcggagtccagcgagctccagggtagagtcggccagctggggctgcgctgggac acggcccagggcgcggtggagagctggcgagagggcttacggcagtccctcctacagtgc caggacttccacgagttgagtcaagatctgttactgtggttggcgagtgctgagagccgg aggcagaaggctcgggtcacggacccagacgcagacccccaggtcctcctggaatgccgg gaagaactgatgcaactggaaagggaacttgtggaacgtcaacctcaagtaaacacctta caagagatttcagacagccttcttattaaggggcatggagaagactatattgaggctgaa gagaaagtgcatgttattgagaagaagctcagacagctactcgagcaagtgtcccaagac ttagtgtccttgcagggacgccagaacccagacccatctctgcccagcttggacgaagta gacgccggagagcagccgccagccgcatccgtgccaactccccaagcaaagttcgaagca gagagaatgacaacagacaagcacaagacagacagcagggtgcccggccccagcagctcc cggccccgccgctccttcgtgtcccgggtgatcagggccgcgctgcccctgcagctgctt ctgctgctgctgctgctcctggcctgcctgctgccctcctccgaagaggactacagctgc actcaggccaacaactttgccaggtccttctaccccatgctgaggtacaccaacgggccc ccccccacctag

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