| Entry |
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| Symbol |
ABCC4
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| Name |
(RefSeq) ATP-binding cassette sub-family C member 4 isoform X1
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| KO |
| K05673 | ATP-binding cassette, subfamily C (CFTR/MRP), member 4 |
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| Organism |
uar Ursus americanus (American black bear)
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| Pathway |
| uar04981 | Folate transport and metabolism |
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| Brite |
KEGG Orthology (KO) [BR:uar00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
123801027 (ABCC4)
09132 Signal transduction
04024 cAMP signaling pathway
123801027 (ABCC4)
09150 Organismal Systems
09154 Digestive system
04976 Bile secretion
123801027 (ABCC4)
04981 Folate transport and metabolism
123801027 (ABCC4)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
123801027 (ABCC4)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:uar02000]
123801027 (ABCC4)
Transporters [BR:uar02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
123801027 (ABCC4)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
1325 aa
MLPGYAEVKPNPLQNANLCSRVFFWWLNPLFKIGHKRRLEEDDMYSVLPEDRSKHLGEEL
QGYWDKEVSRAEKDSRKPSLTKAIIKCYWKSYLVLGIFTLIEEGIKVIQPIFLGKIINYF
ENHDSTSSVALHEAYAYTTALAVCTLILAIMHHLYFYHVQCAGMRLRVAMCHMIYRKGLR
LSNRAMGKTTTGQIVNLLSNDVNKFDQVTIFLHFLWAGPLQAIAVTALLWMEIGISCLAG
ITVLIILLPLQSCLGKLFSSFRSKTATFTDTRIRTMNEVITGIRIIKMYAWEKSFADLIT
HLRRKEISKILSSSYLRGMNLASFFVASKIIVFVTFTTYVFLGNVITASRVFVALSLYGA
VRLTVTLFFPTAIEKVSEAVVSIQRIKNFLLLDEVSQRPPQLPSDGKMIVHVQDFTAFWD
KASETPTLQGLSFTVRPGELLAVIGPVGAGKSSLLSAVLGELPRSHGLVSVHGRIAYVSQ
QPWVFSGTVRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGATLSGGQK
ARVNLARAVYQDADIYLLDDPLSAVDAEVGRHLFELCICQTLHEKITILVTHQLQYLKAA
SQILILKDGRMVQKGTYTEFLKSGVDFGSLLKRENEEADQSPALGSPALRTRSFSASSVW
SQQSSRPSLKDGAPEAQANENTQVALSEESRSEGKVGFKAYKNYLTAGAHCLVIVFLILL
NIVAQVAYVLQDWWLSYWANEQSALNVTVNGKENVTEKLDLAWYLGIYSGLTVATVLFGI
ARSLLVFYVLVHSSQTLHNKMFESILRAPVLFFDRNPVGRILNRFSKDVGHMDDLLPLTF
LDFFQTFLQVLGVVGVAVAVIPWIAIPLIPLGILFFVLRRYFLETSRDVKRLESTTRSPV
FSHLSSSLQGLWTIRAYKAEERFQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAIFV
VVVAFGSLILAKTVDAGQVGLALSYALTLMGMFQWCVRQSAEVENMMISVERVLEYTDLE
KEAPWEYQNRPPPNWPQDGTIVFDNVNFTYSLDGPLVLKHLTVLIKSREKVGIVGRTGAG
KSSLISALFRLSEPEGRIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFNE
HTDEELWNALTEVQLKEAIEDLPGKLDTELAESGSNFSVGQRQLVCLARAILRKNQILII
DEATANVDPRTDELIQKKIREKFAQCTVLTIAHRLNTIIDSDKIMVLDSGRLKEYDEPYV
LLQNEESLFYKMVQQLGKAEAAALTETAKQVYFKRNYPDITHSDHVVMNASNGQPSAFTI
FETAL |
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| NT seq |
3978 nt +upstreamnt +downstreamnt
atgctgcccgggtacgcggaggtgaagcccaacccgctgcagaacgcgaacctctgctcg
cgcgtgttcttctggtggctgaaccccttgtttaaaattggtcacaaacggagattagaa
gaagatgacatgtattcggtgcttccagaagatcgctcaaagcatctgggagaagagttg
caagggtactgggataaagaagtttcgagggccgagaaagactcacggaagccttcttta
acaaaagcgatcataaagtgttactggaaatcctatttagttttgggaatttttacgctc
attgaggaaggcatcaaagtaatccagcccatatttttggggaaaattattaattatttt
gaaaaccatgattccactagttctgtggctttgcacgaagcctacgcctataccacggcg
ctggccgtctgcacactcatcctggccatcatgcatcatttatacttctatcatgttcag
tgcgccggcatgaggctgcgagtcgccatgtgccatatgatttatcggaaggggcttcgc
cttagtaacagggccatggggaagacgaccaccggccagatcgtgaatctcctgtccaat
gacgtgaacaagtttgaccaggtgacaatattcttgcactttctgtgggcagggccactg
caagcgatcgcagtgaccgccttgctctggatggaaataggcatatcctgtcttgctggg
atcaccgttctaattattcttctacccttgcaaagctgcctcgggaagctgttttcatca
ttccggagtaagaccgcaactttcacggacaccaggatcaggaccatgaatgaagttata
actggcataagaataataaaaatgtatgcttgggaaaagtcatttgcagaccttatcacc
catttgagaaggaaggaaatttccaagattctgagcagttcctacctcagaggaatgaat
ttggcatcatttttcgttgcaagcaaaatcatcgtttttgtgactttcaccacctatgtg
tttcttggcaatgtgatcacagccagccgtgtgttcgtcgcactgtcgctctacggggct
gtgcggttgactgttaccctcttcttccccacggccattgagaaggtgtccgaggcagtc
gtcagcatccaaagaatcaagaactttctgttactggacgaggtctcacagcgcccccct
cagctgccgtcagatggtaaaatgatagtgcacgtgcaggacttcactgccttttgggat
aaggcgtcagaaaccccaaccctacaaggcctttcctttactgtgagacccggggaattg
ttagctgtgatcggaccggtgggagcaggaaagtcctcactgttaagtgccgttctgggg
gagctgccccggagccacgggctggtcagcgtgcatggaaggatcgcctacgtttctcag
cagccctgggtgttttcaggaactgtgaggagtaacattttatttgggaagaaatatgaa
aaggaacgatacgaaaaagtaataaaggcttgtgctttgaaaaaggatttgcagcttttg
gaggacggagatttaaccgtgataggcgatcggggagccacgctgagcggagggcagaag
gcccgggtcaacctcgcaagagcggtgtatcaggacgcagatatctacctcctggacgat
cctctcagtgcggtagatgcagaagtcggcaggcacttgtttgaactgtgtatttgccaa
accttgcatgagaagatcacaatcttagtgactcatcagttgcagtacctaaaagctgca
agtcagattctgatattgaaagatggcagaatggtgcagaaggggacttacacagagttt
ctaaaatccggggtagatttcggctcccttttaaagagggaaaatgaggaggctgaccag
agtccggctctaggatctcctgctctgaggactcggagcttctcagcgtcttctgtttgg
tcccagcagtcgtctcgaccgtcgctgaaagatggtgcgccggaggcgcaagctaacgag
aatacacaggttgctctgtcagaggagagtcgttcggaaggaaaagtcggttttaaggcc
tacaagaattacctaacagccggtgcgcactgcttggtcattgtgttcctcattctgctg
aacatcgtagctcaggttgcctatgttcttcaggactggtggctctcctactgggcgaat
gaacaaagtgccctgaatgtcacagtaaatggaaaagaaaatgtcactgagaagctcgat
cttgcctggtacttaggaatttattcaggtctaactgtggctactgtcctctttggcata
gcgagatctctgttggtgttctacgtcctcgttcattcttcacaaactttgcacaacaaa
atgttcgagtccattttgagagctccggtgttgttctttgatagaaacccagtaggaaga
attttaaatcgtttctccaaagacgttgggcacatggatgacttgctacccctgacgttt
ctagatttcttccagacatttctacaagttttgggtgtggtgggcgtggcagtggccgtg
atcccgtggattgcaatacctctaattcccctgggcatccttttctttgttcttcggcgg
tatttcttagaaacttcaagagatgtcaaacgcctggaatctacaacacggagtccggta
ttctcccacttgtcgtcctctctccagggactctggaccatccgggcatataaagctgaa
gagaggttccaggaactgttcgacgcacaccaggatttgcattcagaggcctggttcttg
ttcctgacgacatcccgctggttcgctgtgcgtctggacgccatctgcgccatctttgtc
gttgttgttgccttcgggtccctgattctggcaaaaactgtagatgctgggcaggttggc
ctggcattgtcctacgccctcacactcatggggatgttccagtggtgcgtcaggcaaagc
gccgaagtggagaatatgatgatttcagtggaaagggtgttggagtacacagatcttgag
aaagaagctccttgggaataccagaaccgtcctccaccaaactggccccaggacggcacg
attgtctttgataatgttaacttcacgtacagtttagacgggcctctggttttgaagcac
ctgacagtgctcattaaatcaagggaaaaggttggcattgtgggaagaacaggagctggg
aagagttccctcatctcggccctttttagattgtcagaaccggaaggtagaatttggatt
gataagatcttgacaactgaaattgggcttcacgatctaaggaagaaaatgtccatcata
cctcaggaacctgttttattcactggaacaatgaggaaaaatctggatccctttaacgag
catacggatgaggaactgtggaatgccttaacggaggtacagcttaaagaagccattgaa
gatcttcctggcaaattggacaccgaattagcagaatcaggatcgaatttcagtgtggga
cagagacagttggtgtgcctcgccagggccatcctcaggaaaaaccagatattgatcatt
gacgaagcaacagcaaatgtggacccaagaactgacgaattaatacaaaaaaaaatccgt
gagaaatttgcccagtgcaccgtgctaaccattgcacacaggttgaataccattattgac
agcgacaagatcatggttttggattcaggaagactgaaagaatatgatgaaccgtatgtt
ttgctgcagaatgaagagagcctattttacaagatggtgcagcagctgggcaaggcagaa
gctgctgccctcactgaaacagcaaaacaggtgtacttcaaaaggaattatccagatatt
actcacagtgaccatgtggttatgaatgcttccaatggacagccctcagcctttactatt
tttgagacagccctgtga |
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