Ursus americanus (American black bear): 123801891 Help Entry 123801891         CDS       T07931                                  Symbol TG Name (RefSeq) thyroglobulin   KO K10809   thyroglobulin Organism uar  Ursus americanus (American black bear) Pathway uar04918   Thyroid hormone synthesis uar05320   Autoimmune thyroid disease Brite KEGG Orthology (KO) [BR:uar00001]  09150 Organismal Systems   09152 Endocrine system    04918 Thyroid hormone synthesis     123801891 (TG)  09160 Human Diseases   09163 Immune disease    05320 Autoimmune thyroid disease     123801891 (TG) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  COesterase Thyroglobulin_1 Ephrin_rec_like TNFR_ELAPOR1_6th Motif Other DBs NCBI-GeneID:  123801891 NCBI-ProteinID:  XP_045668151 LinkDB All DBs Position Unknown AA seq 2763 aa AA seqDB search MGLALWVFSLLGSACLVSANIFEYQVDAQPLRPCELQREEAFLKGADHVPQCTEDGSYQT VQCRNDGGSCWCVDADGREVPGSRRPARPAACPSFCQLQKQRILLSGYLNGTATAYLPQC QDSGDYAPVQCDLGREQCWCVDTEGMEVYGTRQRGRLTRCPRSCEIRNRRLLHGVGDKSP PQCSPDGGFLPVQCKFVNTTDMMIFDLVQSYNRFPDAFVTFSAFRKKFPEVSGYCHCADS QGRELAETGLELLLDEIYDTIFAGLDLASTFAESTLVRILQRRFLAVQLVVSGRFRCPTK CEVERFTASSFGHPYIPSCRRNGGYQAVQCQRGGPCWCADAQGKEIHGTQRQGERPSCAE DQFCASERRQALSRLHFGPSGYFSQHRLFLAPEGRQVSPRVARFVTSCPPLIKELFVDSG ILHPMVEGQDQQFSASETLLREAIGAIFPSRELARLALQFTTDPKRLQQNLFGGKFLVNV GQFNLSGALGTKGTFNFSQFFQQFGLPGFRNGGTNLSKPLSLGFDADPATEPPEASKKGA ATNRPIVGSFGFEINLQENQNALTFLSSLLELPEFLLFLQQALSVPEDIARDLGDVMEIV LSSQGCEQTPGSLFVPRCSAEGSYEDVQCFAGECWCVDSRGKELAGSRVRGARPRCPTEC EKQRALMRILSGSLPAGASLFVPSCSSEGHFLPVQCFNSECYCVDAEGQAIPGTRSVPGD PKPCPTPCQLQAEKAFLGVARALGSGSSMPPSFSSSYVPQCSTSGQWRPVQCDGPPEQAF EWYERWGAQNNSGQELTPAELLGKIMSYREAASGSFQLFIQSLYEAGQQGIFPGLARYPS FQDIPLAVMEGNLTQPGGNILLEPYVFWQILNGQLSRYPGSYSDFSTPLAHLDLRSCWCV DEAGQELEGTRTEPSKAPACPGSCEKVKLRVLQFIKETEEIVLASNSSWFPLGESFLAAK GIRLTDEELSLPPLSPSRESFSEKFLSGGDYAIRLAAQSTLDFYQRRGFLLGDSTRASAL PRPGPYVPQCDAWGGWEPVQCHAGTGYCWCVDGKGEYVPASLTARSPQIPQCPTSCETSR ASGLLSSWKQAASQGNPSPKDLFIPTCLETGEFARLQESEAGSWCVDPASGAGMPPGTNS STPCPSLCEVLPSGVLSKRASSVYTPACRAEDGGFSPVQCDPAQGSCWCVLDSGEEVPGT RVAGSQLACESPQCPLPFNTSDVAGGVILCERASGAGGAPIQRCQLRCHRDYRSAFPPGL LVCSLEKGRWESQPPQPQACQRPQLWQTLQTQGQFQLRLPPGKMCSADYAGLLLAFQVFI LDELMARGFCEIQAKTFGTPVSIPVCDGSTVRVDCLAGERLGVNVTWKLQLKDVPPASLP DLHDIEEALVGKDLIGRFTDLIQSGGFQLHLDSKTFPADTSIYFLQGDRLGTSPRTWFGC LEGFRQVLATSNATQDPLGCVKCPEGSYFQKEICIPCPVGFYQERAGSVACIRCPMGRTT ISPGAFSPMHCVTDCQRSEAGLQCDQDGQYRASQRDRDSRKAFCVDGEGQRLPWSETDGL LSDSQCLMMRKFEKALESQVIFGANVTAVGRSKVPGSESPLMQCLTDCALDTACSFLTVS SAGSEVSCDFYAWSSDNIACVTSAQHQDTLGNSKATGSGSLRCQVTVRSGAQDPPSVYLK KGHEFNTTSQKSFEQTGFQNTLSGMYGPVVFPASGADLTGAHLFCLLACDRDSCCDGFIL AQVQGGPIICGLLSSPDVLLCNVKDWRDPAEAQANATCPGVTYDQGSRQVTLRLGGQEFQ SNLRPMEGSPDTITSFQQVYLWEDSDMGSRPESLGCRRDVEPRAASPTETDLTTELFSPV DLNQIIVNGSRSLPSQQHWLFKHLFSPQQANLWCLSRCVQEPSFCQLAEITDNAPLYFTC ALYPEAQVCDDVMESNPKGCRLILPHRPKTLFRKKVILRDKVKHFYTRLPFQTLTGISVR NKVPMSEKSISSGFFECERLCDADPCCTGFGFLNVSQLKGGEVTCLTLNSLGLQTCTEEN RGAWRILDCGSPDTEVRTYPFGWYQKPVAQNDAPSFCPSVVLPSLPEKVALGSWQSLAPS AVVVDPSIRNFDVAHISTATTSDFSDARNFCLLECSRHQTCLVTTLQTRPGAVRCVFYAD TQICTHSLQAQHCQLLLREEATYIYRKLNIPLLSSGTPAPSVTIAPYGRLLGRSQAVQVG GSWRQVDQFLGVPYAAPPLAESRFQAPGPLNWTGSWDATKPRASCWQPGTRAPASPGVSE DCLYLNVFVPQNVAPNASVLVFFHNTMEGKGAGGQLAIDGSFLAAIGNLIVVTAGYRVGV FGFLSSGSGEVSGNWGLLDQRAALTWVQTHIGVFGGDPRRVTLAADRGGADVASIHLLTT RAADSRLFRRVMLMGGSAFSPAAVISQGRAQQQAAALAEEISCPTSSMQEMVSCLRQKPA SVLNDAQTKLLAVSGPFHYWGPVVDGQYLREAPARALQRTPRVKVDLLIGSSQDDGLINR AKAVKQFEESQGRTSSKTAFYQALQNSLGGEDADAGVRAAATWYYSLEHSTDDYASFSRA LENATRDYFITCPVIDMASHWARRARGNVFMYHSPESYGHSSLDLLADVRSAFGLPFYPA YKGQFTLEEKSLSLKIMQFFSNFIRSGNPNYPHEFSRKAPEFAAPWPDFVPRAGGESYKE LSVLLPNRQGLKSADCSFWSKYIRSLKAAAAGGEAGLSAESEEEDGLADTGLLGEPGSKS YSR NT seq 8292 nt NT seq  +upstreamnt  +downstreamnt atgggcctggccttgtgggtcttcagtctgctgggctcagcctgcttggtgtcggccaac atcttcgagtaccaggtggacgcccagcccctgcgtccttgcgagctgcagagggaggag gcctttctgaagggagcagaccacgttccccagtgcacagaagacggcagctaccagacc gtccagtgccggaatgacgggggctcctgctggtgcgtggatgccgacggcagggaggtg cccggcagcaggcggcctgctcggcccgcggcctgtccatctttctgccaactgcagaag cagcggatcttgctgagcggctaccttaacggcacggccacagcctacctcccccagtgt caggattcgggggattacgcgcccgtgcagtgtgacctggggcgggagcagtgctggtgt gtggacacagaagggatggaggtgtacgggacacgccagcgagggaggctgacacggtgt cccaggagctgtgagataagaaaccgccgtcttctccacggggtgggagacaagtcacct ccccagtgttctccagatgggggcttcctgcctgtccagtgcaagtttgtcaacaccaca gacatgatgatttttgacctggttcagagctacaacaggtttccagatgccttcgtgacc ttcagtgccttccggaaaaagttccccgaggtgtctgggtattgtcactgtgcggacagt caagggcgggagctggctgagacaggtttggagctgttacttgacgaaatttacgacacc atctttgccggcctggacctcgcttccacgttcgccgaaagcaccctggtgcggatattg cagagacggttcctagccgttcagctcgtcgtctctggccgattccgatgccccacaaaa tgtgaagtggagcggttcacagcgagcagctttggtcacccctacattccgagctgccgc cgcaacgggggctaccaggcggtgcagtgccagcggggagggccgtgctggtgtgcggac gcccaagggaaggagatccatggaacacagcggcaaggcgaacgaccgtcctgtgctgaa gaccaattctgtgcctcagagaggaggcaggccctgtctagactacacttcgggccctca ggctacttcagccagcacaggttgttcttggctcctgagggaagacaggtgtctccgaga gtagccagatttgtcacatcctgcccacccctgatcaaggagctctttgtggactctggg attctccacccaatggtagaagggcaggaccaacagttttctgcctcagaaactctcctc agagaagccattggagcgatttttccttcccgagagctggctcgtcttgcccttcagttt accaccgacccaaagcgcctccagcaaaacctctttggagggaaatttttggtgaatgtt ggccagttcaacctgtctggagcccttggcacaaaaggcacatttaacttcagtcaattt ttccagcagtttggtctcccaggcttccggaatggagggaccaatctatccaagcccctc tccttgggatttgatgcagatcctgccacagaaccccctgaagcctctaagaagggagct gctacgaataggccgattgtgggcagctttggctttgagatcaacttgcaagagaaccaa aatgccctgacattcctttcctctctcctggagcttccagaattccttctcttcctgcag caggctctttcggtgccagaagacatagcgagggatctgggtgacgtgatggaaattgtg ctcagctcccagggctgtgagcagacgcctggcagtcttttcgtcccacggtgctcggca gaaggaagctacgaggatgtccagtgctttgccggggagtgctggtgtgtggattcccgg ggcaaagaacttgctggctccagggttaggggtgcacggcccaggtgccccacagagtgt gagaagcaaagggctctcatgcgaatcctctcgggcagcctgcccgctggggccagcttg tttgtcccttcttgtagcagcgaggggcatttcctacccgtccagtgcttcaactcagag tgctactgcgtggacgccgagggtcaggctattcctggaactcgaagcgtgcctggagac cccaagccatgccccaccccctgtcagttacaggccgagaaagccttccttggggtcgcg cgagcgctgggctccggttccagcatgccgccctccttctccagcagctacgtcccgcag tgcagcaccagcgggcagtggaggcccgtgcagtgcgacgggccccccgagcaggccttc gagtggtacgagcgatggggggcccagaacaacagtggccaggagctgacccctgctgag ctgctagggaagatcatgagctatcgagaagcagcttccggaagcttccaactctttatt caaagtctgtatgaggctggccaacagggcatcttcccagggctggcgagatacccttct ttccaagacatcccactggcagtgatggaaggcaacctgacccagcctggtgggaacatc cttctggaaccctacgtcttctggcagatcctgaatggccagctcagccggtacccaggg tcctactcagacttcagcactcctctggcgcacttggaccttcggagctgctggtgcgtg gatgaagctggtcaagaactggaaggcacccggacagagccgagcaaggccccagcatgt cctggctcttgtgagaaggtgaagcttcgtgtcctgcagttcattaaggaaacagaagag atcgtcttggcttccaacagttcttggttccctctgggagagagtttcctagcggccaaa ggaatccggctgaccgatgaggaactctcccttcctccactctctccatcccgggagtct ttctcagagaagtttctgagtgggggcgattatgccattcgtctggcggctcagtctacc cttgacttctatcaaagacgtggctttctcctgggggattccacacgcgcatccgccctt ccgcggcccggcccctacgtgccccagtgcgatgcgtggggaggctgggagcccgtgcag tgccatgccgggactgggtactgctggtgtgtggacgggaagggagagtacgttcctgcc tcgctgactgcccgctccccacagatcccccagtgccccacctcctgtgagacatctcga gccagtgggctgctttccagttggaaacaggctgcatcccagggaaacccatctccaaaa gacctgttcatcccaacctgcctggagacaggagagtttgccaggctgcaggagtcggag gccggcagctggtgtgtggacccggcctcgggggccggcatgccacccggcacgaacagc agcaccccatgcccaagcctctgtgaagtactcccgagtggggtcctgtccaagagagcc agctcagtctataccccagcctgcagggcagaagacggaggattttcccccgtgcagtgt gatccagcccagggcagctgctggtgtgtcctggacagtggagaggaggtgcctgggacc cgtgtggccgggagccagctggcctgtgagagcccccagtgcccgctgcccttcaacacg tcggatgtggctggtggagtgatcctgtgtgagcgagcctcgggcgcgggaggggccccc atccagcggtgccagctgcggtgccaccgggactaccggagcgcctttccgccggggctg ctggtgtgcagcctcgagaagggacgctgggagtcccaaccgccccagccccaggcctgc cagcggccccagctctggcagaccctccagacccaagggcagttccagctccggctcccg ccaggcaagatgtgcagcgctgactatgcgggcttgctgctggccttccaggtgttcata ttagacgagctcatggcccggggcttctgtgagatccaggcgaagacatttgggacccct gtttccattcctgtctgtgacggatccacggtgcgggtggactgtctggccggggagcgt ttaggagtgaacgtcacgtggaagttgcagctgaaggacgtcccaccggcctctcttcct gatttgcatgacattgaggaagccttagtcggcaaggatctcattggacgcttcacagat ctgatccagagtggagggttccagcttcatctagattccaagacattcccagcagacacc tccatctatttccttcaaggagaccgccttggcacctctcccaggacatggtttgggtgc ttggaaggatttcgccaagtcttggctaccagcaatgccactcaggacccactggggtgc gttaagtgtcctgaaggaagctattttcagaaggagatttgtattccctgtcctgttgga ttctaccaagaacgggcagggagcgtggcctgcatccgatgtcccatgggcagaacgacc atttcccctggagctttcagccccatgcactgtgtcactgactgtcagaggagcgaggct gggctgcagtgtgaccaggacggccagtaccgagccagccagagagaccgggacagtcgg aaggccttctgcgtggacggcgaggggcagaggctgccgtggtcggaaacagacggcctg ctctctgactcccagtgtctgatgatgcggaaatttgagaaggctctagaatctcaggtg atcttcggtgccaatgtcactgcagtgggcaggtccaaagttcctggctctgagtccccc ctgatgcagtgcttgacagactgtgctttggacacggcctgcagcttcctcacggtgtcc tcggcgggatcagaggtctcgtgtgatttttatgcttggagcagcgacaacatcgcctgc gtgacttcggctcagcatcaagacacactggggaactcaaaggccaccggctctggaagt cttaggtgccaggtgacggtgaggagcggggctcaagatcccccgtctgtgtatctgaaa aagggccacgagttcaacacaacgagtcagaagagctttgagcaaacgggtttccagaac acactctctggaatgtacgggcccgttgtgttcccagcctctggagctgatctgacaggg gctcatctcttctgtcttctggcgtgtgaccgtgattcgtgctgtgacggcttcatcctt gcccaggtccaaggaggtcccatcatctgtgggttgctgagctcccccgatgtcctactt tgcaatgtcaaggactggagggaccccgctgaagcccaggccaatgccacatgtcctggt gtgacatacgaccaggggagccgccaggtgacgttgcgtctgggaggccaggagttccag agtaatctgagacccatggaaggatctccggacaccattaccagcttccaacaggtttat ctctgggaagattctgacatggggtctcgacctgagtccctgggatgtagaagagacgta gaaccaagggcagcctctccaacagaaacagatttgacgacagaacttttctcccctgtg gatcttaaccagattattgtcaacggaagccgatctctgcccagccagcagcactggctt ttcaaacacctgttttcacctcagcaggcaaacctgtggtgcctgtctcgctgtgtgcag gagccctctttctgtcagctggcggagataacagacaacgcacccttgtatttcacctgt gccctctacccagaggcccaggtgtgtgacgatgtcatggagtccaatcccaagggctgc agactgatcctgccccacaggccaaagaccctattccggaagaaagttatactgagagat aaagtgaagcacttttacactcgcctgccattccaaacattgacggggatttccgttaga aacaaagtgcccatgtctgaaaaatccatttccagtggcttcttcgaatgtgaacggcta tgtgacgcggacccgtgctgcaccggctttggctttctcaatgtttcccagttgaaagga ggagaggtgacatgcctaactctaaacagcctgggacttcagacgtgcactgaggaaaac agaggagcctggcgcattttggactgtggctctcctgacacagaggtccgcacctatccc tttggatggtaccagaaacctgttgctcagaatgatgctcccagtttttgcccctccgtg gttctgccttccctcccggagaaagttgctctgggctcatggcagtccctggccccctct gcggtagttgttgacccgtccatccggaacttcgatgttgctcacatcagcactgccacc accagcgacttctctgatgccagaaacttctgtttgttggaatgttcccgtcaccagacc tgcctcgtcaccactctgcagacccgacctggtgctgtgaggtgtgtattctatgctgac acccagatctgcacacatagcctgcaggcccagcactgccaacttctgctccgggaggag gccacctacatctaccggaagctgaacatccctctgctcagctctgggacacctgcacct tctgtgaccatcgccccctacggccggctgctgggcaggtcccaggccgtccaggtgggc ggttcgtggaggcaagtggatcagttcctgggagttccgtacgccgccccgcccctggca gagagccgcttccaggcaccggggcccttgaactggacagggtcctgggatgccaccaag ccacgggccagctgctggcagccaggcaccagagcgcccgcgtcgcccggagtcagcgaa gactgcttgtatcttaacgtgtttgtccctcagaacgtggcccccaacgcgtctgtgctg gtcttcttccacaacaccatggaggggaagggggctggaggacagctggccatcgatggc tccttcctggctgctattggcaacctcattgttgtcactgctggctaccgagtgggggtc ttcggcttcctgagttccggttctggcgaggtgagtggcaactgggggctgctggaccag cgggcggctctgacctgggtgcagacccacatcggagtgttcggtggggaccctcggcgc gtgaccctggcagcagatcgtggcggtgccgacgtggccagcatccaccttctaaccacc agggccgctgactccagactcttccggagggtcatgctgatgggtggctccgcgttctcc ccagctgctgtcatcagccaggggagggctcagcagcaggcagccgctttggcggaggag atcagctgccccacctcgtccatgcaagaaatggtgtcctgtctccgccagaagcctgcc agtgtcctcaatgacgcccagaccaagctcctggccgtgagtggccctttccactactgg ggtcctgtggttgatggccagtacctccgagaggctccagcaagagctcttcagaggaca ccgcgggtgaaggtcgatctgctgattgggagttctcaagatgacgggctcatcaacaga gcgaaagccgtgaagcaatttgaggaaagtcaaggccggaccagtagcaagacagccttt taccaggcgctgcagaattcgctgggcggtgaggacgcagacgccggtgtccgggcggct gctacttggtactactccctggaacattccaccgatgactacgcctccttctcccgggcc ctggaaaacgccacccgggactactttatcacctgtcctgtaatcgacatggccagccac tgggcgaggagggcccgaggaaacgtcttcatgtaccactctcccgaaagctatggccac agcagcctggatttgctggcggatgttcggtctgcctttgggcttcctttctaccccgcc tacaaggggcagtttactctggaggagaaaagcctgtccctgaagatcatgcagttcttt tcgaacttcatccgatcgggaaaccccaactacccgcatgagttctccaggaaagcccct gagtttgcagccccgtggcctgacttcgtcccgcgggccggcggggagagctacaaggag ctcagcgtcctgctccccaatcgacagggcctcaaaagcgctgactgctccttctggtcc aagtacatccggtctctgaaggcggcggcggcaggtggggaagccggattgtcagcagag agtgaagaggaggacgggctggctgacactgggctgttaggagagccaggctccaagagc tacagcaggtga

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