Ursus americanus (American black bear): 123803837 Help Entry 123803837         CDS       T07931                                  Symbol PLA2G4F Name (RefSeq) cytosolic phospholipase A2 zeta   KO K16342   cytosolic phospholipase A2 [EC:3.1.1.4] Organism uar  Ursus americanus (American black bear) Pathway uar00564   Glycerophospholipid metabolism uar00565   Ether lipid metabolism uar00590   Arachidonic acid metabolism uar00591   Linoleic acid metabolism uar00592   alpha-Linolenic acid metabolism uar01100   Metabolic pathways uar04010   MAPK signaling pathway uar04014   Ras signaling pathway uar04072   Phospholipase D signaling pathway uar04217   Necroptosis uar04270   Vascular smooth muscle contraction uar04370   VEGF signaling pathway uar04611   Platelet activation uar04664   Fc epsilon RI signaling pathway uar04666   Fc gamma R-mediated phagocytosis uar04724   Glutamatergic synapse uar04726   Serotonergic synapse uar04730   Long-term depression uar04750   Inflammatory mediator regulation of TRP channels uar04912   GnRH signaling pathway uar04913   Ovarian steroidogenesis uar04921   Oxytocin signaling pathway uar05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:uar00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     123803837 (PLA2G4F)    00565 Ether lipid metabolism     123803837 (PLA2G4F)    00590 Arachidonic acid metabolism     123803837 (PLA2G4F)    00591 Linoleic acid metabolism     123803837 (PLA2G4F)    00592 alpha-Linolenic acid metabolism     123803837 (PLA2G4F)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     123803837 (PLA2G4F)    04014 Ras signaling pathway     123803837 (PLA2G4F)    04370 VEGF signaling pathway     123803837 (PLA2G4F)    04072 Phospholipase D signaling pathway     123803837 (PLA2G4F)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     123803837 (PLA2G4F)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     123803837 (PLA2G4F)    04664 Fc epsilon RI signaling pathway     123803837 (PLA2G4F)    04666 Fc gamma R-mediated phagocytosis     123803837 (PLA2G4F)   09152 Endocrine system    04912 GnRH signaling pathway     123803837 (PLA2G4F)    04913 Ovarian steroidogenesis     123803837 (PLA2G4F)    04921 Oxytocin signaling pathway     123803837 (PLA2G4F)   09153 Circulatory system    04270 Vascular smooth muscle contraction     123803837 (PLA2G4F)   09156 Nervous system    04724 Glutamatergic synapse     123803837 (PLA2G4F)    04726 Serotonergic synapse     123803837 (PLA2G4F)    04730 Long-term depression     123803837 (PLA2G4F)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     123803837 (PLA2G4F)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     123803837 (PLA2G4F) Enzymes [BR:uar01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      123803837 (PLA2G4F) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  cPLA2_C2 PLA2_B C2 Motif Other DBs NCBI-GeneID:  123803837 NCBI-ProteinID:  XP_045671541 LinkDB All DBs Position Unknown AA seq 849 aa AA seqDB search MHRVLGPRWLAGKGLPLLGAVLLRKREKRGLQWRQLRRETHPYYDLQVKVLRARNIQGTD LLSKADCYVQLCLPTASSSPTRTRMVANCSDPKWDETFHYQIHGAVKNVLELTLYDKDVL DSDQLSLLLFDLRSLQPGQPYRHTFLLNHQDSQELQVEFFLENSQVPASEVITNGVLVAH PCLRIQGTLGEDGTAPPREYGSRHIRLTVPGAYEKPQLLPLQPHKEGGLPATFIFHVNPV ISSRLDVELGEKLTVLQSGPSAELETQTSKLGEGGILLSSLALGQEEQRFVALGEDQEVV LSMKAEMSSGDLDLRLGFDLCDGEQEFLDKRKQIVSKALQQVLGLSQAPDGGQVPVVAVL GSGGGTRAMSSLYGSLAGLQELGLLDTVTYLSGVSGSTWCISTLYQDPAWSQVALQGPIE RAQARVCSSKMGAMSPERLQYYAQELGSLEGSGHSVSLIDLWGLLIEYFLYQEENPARLS DQQEAVSQGQNPYPIYASINVRTNISGEDFAEWCEFTPHEVGFPKYGAYVPTELFGSEFF MGHLLQPRPEPRICYLQGMWGSAFAASVDEIFLKTAGSGLSFLDGHRGKVNITDDCQKLQ LHDPTRLRTRLFTPQGPFSQAVLDIFTSRFTSAENFNFTRGLCLHKDYVAGREFMAWKAT HPDAFPNQLTPMRDCLCLVDGGFAINSPFPLNLLPQRAVDLILSFDYSLEAPFEVLQMTE KYCLDRGIPFPRIEVLPEDLEEPRECYLFTEAKDPRSPIVLHFPLVNRTFRTHLAPGVER QTPEEKARGDFAVNGSDTPYGMMNFTYEPEEFERLVALSRYNVLNNAETVRQALRLALQQ RQAGDRAGG NT seq 2550 nt NT seq  +upstreamnt  +downstreamnt atgcaccgggtgctcgggccaaggtggctggcaggcaaggggctgcccctcctgggggca gtgctgctgcgcaagagagagaagaggggacttcagtggaggcaattgcggcgggaaacc cacccatactatgacctccaggtgaaggtgctgagggccagaaatatccagggcacagat ctgctgtccaaagccgattgctatgtgcaactgtgcctgcccactgcgtcctccagcccc acccggacaaggatggtggccaactgcagtgaccccaagtgggatgagaccttccactac cagatccacggtgctgtgaaaaatgttctggagctcaccctctatgataaggatgtcctg gacagtgaccagctctccctgctactgtttgacctgaggagcctgcagcctggccaaccc tacaggcataccttcctactcaaccaccaggattcccaagagctgcaggtggaatttttt ctggagaacagccaggtgcccgcatctgaagtcatcaccaacggggtcctggtggctcac ccctgtctgagaatccagggtaccctcggggaagatggcacagctccacctcgagagtat ggctctaggcatattcggctgacagtgcccggggcctacgagaagccacagctcttgccc ctgcaaccccacaaagagggaggccttccagccaccttcatctttcacgtgaatccagtg atcagctccaggctggatgtggagctgggggagaagctcacagtcctgcagagtggccca agtgctgaactggagacccagaccagcaagctgggcgaggggggcatcctgctctcttct ttggccttaggccaggaggaacagcgtttcgtggccttgggggaggaccaggaggtggtt ctgagtatgaaggcagaaatgagctctggagaccttgacctgcgccttggctttgacttg tgtgacggggaacaggagtttctggacaagaggaagcagatcgtgtctaaggccctgcag caggtgctgggattgagccaggctcctgacggtggccaggtgcctgtggtggctgtgctg ggttccggaggtggaacccgagccatgtcttccctgtacggcagcctggcagggctgcag gaactcggcctcctggacactgtgacctacctgagcggggtctctgggtctacctggtgc atctccaccctctaccaggacccagcctggtcccaggtggccttgcagggccccattgag cgtgcccaggctcgggtctgcagcagtaagatgggggcgatgtccccggagcgcctgcag tactatgcccaggaactggggagcttggaaggcagcggccacagtgtttccctcatcgac ctctggggtctcctcattgaatatttcctctaccaggaggaaaaccccgccaggctgtct gaccagcaggaggctgtcagccagggccagaacccttacccgatctacgccagcatcaat gtccgtaccaacatcagcggggaggactttgcagagtggtgcgagttcaccccccatgaa gtcggcttccccaagtatggggcttatgtccccactgagctctttggctctgagttcttc atggggcatctgctgcagccccggcccgagccccggatctgctacctgcagggtatgtgg ggcagtgcctttgcagccagcgtggatgagatcttcctgaagactgctggctcgggcctc agcttcctagatgggcacagagggaaggtaaacatcacagatgactgccagaagctccag ctgcatgaccccacacgtctgcgaaccaggctcttcaccccccagggccccttctcccag gctgtgctggacatattcacctcccgctttacctccgcagagaactttaatttcaccagg ggcctctgcctacacaaagactatgtagctggccgggagttcatggcctggaaagctacg caccctgacgccttccccaaccagctcactcccatgcgggactgcctgtgcctggtggat gggggctttgccatcaactctccgttcccactgaacctgctgccccagagagcggtggac ctcattctgtcctttgactactccctggaggccccttttgaggtcttacagatgacagag aagtactgcctggaccgaggcatccccttcccaaggattgaggtgctccctgaggacttg gaggagccccgagagtgctacctgttcaccgaggccaaggacccccgctcacccattgtg ctgcacttcccccttgtcaaccgtaccttccgcacacaccttgcaccaggtgtggagcga caaacacctgaggagaaggcccgtggggactttgccgtcaacgggtcagacacgccctat ggcatgatgaacttcacctatgagcctgaggagtttgagcggctggtggctctgagtcgc tacaatgttctgaacaacgcagagaccgtgaggcaggccctccggctggctctgcagcag cggcaggctggggacagggccggaggctga

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