| Entry |
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| Symbol |
PDGFRA
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| Name |
(RefSeq) platelet-derived growth factor receptor alpha isoform X1
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| KO |
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| Organism |
uar Ursus americanus (American black bear)
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| Pathway |
| uar01521 | EGFR tyrosine kinase inhibitor resistance |
| uar04072 | Phospholipase D signaling pathway |
| uar04810 | Regulation of actin cytoskeleton |
| uar05163 | Human cytomegalovirus infection |
| uar05230 | Central carbon metabolism in cancer |
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| Brite |
KEGG Orthology (KO) [BR:uar00001]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
123804080 (PDGFRA)
04014 Ras signaling pathway
123804080 (PDGFRA)
04015 Rap1 signaling pathway
123804080 (PDGFRA)
04630 JAK-STAT signaling pathway
123804080 (PDGFRA)
04020 Calcium signaling pathway
123804080 (PDGFRA)
04072 Phospholipase D signaling pathway
123804080 (PDGFRA)
04151 PI3K-Akt signaling pathway
123804080 (PDGFRA)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
123804080 (PDGFRA)
09144 Cellular community - eukaryotes
04510 Focal adhesion
123804080 (PDGFRA)
04540 Gap junction
123804080 (PDGFRA)
09142 Cell motility
04810 Regulation of actin cytoskeleton
123804080 (PDGFRA)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123804080 (PDGFRA)
05206 MicroRNAs in cancer
123804080 (PDGFRA)
05230 Central carbon metabolism in cancer
123804080 (PDGFRA)
05231 Choline metabolism in cancer
123804080 (PDGFRA)
09162 Cancer: specific types
05214 Glioma
123804080 (PDGFRA)
05218 Melanoma
123804080 (PDGFRA)
05215 Prostate cancer
123804080 (PDGFRA)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
123804080 (PDGFRA)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
123804080 (PDGFRA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:uar01001]
123804080 (PDGFRA)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:uar04090]
123804080 (PDGFRA)
Enzymes [BR:uar01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
123804080 (PDGFRA)
Protein kinases [BR:uar01001]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
123804080 (PDGFRA)
CD molecules [BR:uar04090]
Proteins
123804080 (PDGFRA)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
1089 aa
MGTSLLAFLILGCLLTGPSRVFCQLSLPSILPNENEKVVQLNSSFSLRCFGESEVSWQYP
MSEEENPNVEIRNEENNSGLFVAVLEVVSAVAAHTGLYTCYYNHTQTEETDIEGRRIYIY
VPDPDVAFVPLGMTDYLVIVEDDDSAIIPCRTTDPETPVTLRSNDGVVHASYDSRQGFNG
TFSVGPYICEATVRGKKFQTIPFNVYALKATSELDLEMEALKTVYKSGETIVVTCAVFNN
EVVDLQWTYPGEVKGKGITMLEEIKVPSIKLVYTLRVPEATVKDSGDYECAARQATKEVK
EMKKVTISVHEKGFIEIKPNFSPLEAVDLHEVKHFVVDVQAYPPPRISWLKDNLTLIENL
TEITTDIEKIQEIRYRSKLKLIRAKEEDSGHYTIVVQNEDDVKSYTFELLTQVPSSILDL
VDDHHGSTGGQTVRCTAEGTPLPDIEWMICKDIKKCNNETSWAILANNISNIITEVHPRD
RSTVEGRVTFTRVEETIAVRCLAKNLLGAESRELKLVAPTLRSELTVAAAVLVLLVIVII
SLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILG
SGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNL
LGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSRHPEKPKKELDIFGLNPADDSTRSY
VILSFENNGDYMDMKQADATQYVPMLERKEAAKYSDIQRSLYDRPASSKKKSVLDSEVKN
LLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLA
RDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMM
VDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWHSEPEKRPSFYHLSEIVENLLPGQYKK
SYEKIHLDFLKSDHPAVARMRVDADNAYIGVTYKNEEDKLKDWEGSLDEQRLSADSGYII
PLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDS
SDLVEDSFL |
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| NT seq |
3270 nt +upstreamnt +downstreamnt
atggggacttcccttctggccttcctgatcttaggctgtctcctcacagggcccagcaga
gtcttctgccagctttcattaccctccatcctgccaaacgaaaatgaaaaggtcgtgcag
ctgaattcatccttttctctgagatgctttggggagagtgaagtgagctggcagtacccc
atgtctgaagaagagaaccccaatgtggaaatcagaaacgaggagaacaacagcggcctt
tttgtggccgtgctggaggtggtcagcgcggtggcggcgcacacgggcttgtacacctgc
tattacaaccacacccagacggaggagaccgacatcgagggcaggcgtatctacatctac
gtgccagacccggatgtagccttcgtgcctctgggaatgacagattatttagtcatcgtg
gaggatgatgattctgccatcataccttgtcgcacgactgatcccgagactccggtcacc
ttgcgcagcaatgacggggtggtgcacgcctcctatgacagcagacagggcttcaatggg
accttcagcgttgggccctatatctgtgaagccaccgtcaggggaaagaagttccagacc
atcccatttaatgtttatgctttaaaagcaacgtcagaacttgatctagaaatggaagct
cttaaaactgtgtataagtcaggggagacgattgtggtcacctgcgccgtctttaacaac
gaggtggtcgaccttcagtggacttaccctggagaagtgaaaggcaaaggcatcaccatg
ctggaggaaatcaaggtcccgtccatcaaattggtgtatactctgagggtccccgaggcc
acggtgaaagatagtggagattatgaatgtgctgcccgccaggccaccaaggaggtcaaa
gagatgaagaaagtcaccatttctgtccatgagaaagggttcattgaaatcaaacccaac
ttcagcccgttggaagctgtcgacctgcatgaagtcaaacatttcgtggtggacgtgcag
gcctacccccctcccaggatatcctggctgaaggacaacctgactctgattgaaaatctc
acggagatcaccacggacatagaaaagattcaggaaataaggtatcggagcaaattaaag
ctgatccgtgctaaggaggaagacagtggccattacacgatcgtcgttcaaaatgaagat
gacgtgaagagctatactttcgaactcctaactcaagttccctcatctattctggacttg
gtggacgaccaccacggctccacggggggacagactgtgagatgcaccgccgaagggacg
cctcttcctgatatcgagtggatgatttgcaaggatattaagaagtgtaataatgaaact
tcatgggcgattttggccaacaatatctcaaacatcatcacggaggtccacccccgagac
aggagcactgtggagggccgagtgacgttcaccagagtggaggagaccatcgccgttcga
tgtctggccaagaatctccttggggccgagagccgcgagctcaagctggtggctcccacg
ctgcgctctgagctcacggtggccgctgccgtcctcgtgctgctggtgattgtcatcatc
tccctcatcgtcctggttgtcatttggaaacagaaaccgaggtatgaaattcgctggagg
gtcattgaatccatcagcccggatggacatgaatatatttatgtggacccgatgcagctg
ccttatgactcgagatgggagtttccaagagatggactagtgcttggtcgtatcctggga
tctggcgcgtttgggaaagtggttgaaggaactgcctatggattaagccgctcccagcct
gtcatgaaggtagcagtgaagatgctgaaacccacagccagatccagtgagaaacaggct
cttatgtcggaactgaagataatgactcacctggggccgcatttaaacattgtgaacttg
ctgggagcctgtaccaagtcaggccctatttacatcatcactgagtactgcttctatggg
gatttggtcaactatttgcataagaatagggatagcttcctgagccgccacccggagaag
ccaaagaaagagctggacatttttggattgaaccctgccgacgacagcacacggagttac
gtcattttatcttttgaaaacaacggtgactacatggacatgaagcaagctgacgccacc
cagtacgtccccatgctggaaaggaaagaggctgccaagtactcagacatccagagatcg
ctgtatgatcgcccggcctcgtctaagaagaagtctgtgttagactcagaagtcaaaaac
ctcctttcggatgataactcagaaggccttactttgttggatttgttgagctttacctat
caagttgcacgaggaatggaatttttggcttcgaaaaattgtgtccaccgggacctggct
gctcgaaacgtcctcctggcgcaagggaaaatcgtgaagatctgtgacttcggcctggcc
agagacatcatgcacgattcgaactacgtgtcaaaaggcagtacctttctccctgtgaag
tggatggcccctgagagcatcttcgacaacctctacaccacactgagtgacgtctggtct
tacggcattctgctctgggagatcttttccctcggcggcacaccctaccccggcatgatg
gtggattctactttctacaataagattaagagtgggtaccggatggccaagcctgaccat
gccaccagtgaagtctacgagatcatggtgaaatgctggcacagtgagccggagaagaga
ccctccttctaccacctgagtgagattgtggagaacctgctgcccggacagtataagaag
agttacgaaaagattcacctggacttcctgaagagcgaccaccccgccgtggcgcgcatg
cgcgtggacgccgacaacgcctacattggcgtcacctacaaaaacgaggaagacaagctg
aaggactgggagggcagcctggacgagcagaggctgagcgcggacagcggctacatcatc
cccctgcccgacatcgaccctgtccctgaggaggaagacctgggcaagaggaacagacac
agctcgcagacctcagaagagagtgctatcgagacaggttcgagcagctccaccttcatc
aagagagaggacgagaccatcgaggacatcgacatgatggacgacattggcatagactcc
tcagacctggtagaggacagcttcctgtga |
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