Ursus americanus (American black bear): 804835 Help Entry 804835            CDS       T07931                                  Symbol COX1 Name (RefSeq) cytochrome c oxidase subunit I   KO K02256   cytochrome c oxidase subunit 1 [EC:7.1.1.9] Organism uar  Ursus americanus (American black bear) Pathway uar00190   Oxidative phosphorylation uar01100   Metabolic pathways uar04260   Cardiac muscle contraction uar04714   Thermogenesis uar04932   Non-alcoholic fatty liver disease uar05010   Alzheimer disease uar05012   Parkinson disease uar05014   Amyotrophic lateral sclerosis uar05016   Huntington disease uar05020   Prion disease uar05022   Pathways of neurodegeneration - multiple diseases uar05208   Chemical carcinogenesis - reactive oxygen species uar05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:uar00001]  09100 Metabolism   09102 Energy metabolism    00190 Oxidative phosphorylation     804835 (COX1)  09150 Organismal Systems   09153 Circulatory system    04260 Cardiac muscle contraction     804835 (COX1)   09159 Environmental adaptation    04714 Thermogenesis     804835 (COX1)  09160 Human Diseases   09161 Cancer: overview    05208 Chemical carcinogenesis - reactive oxygen species     804835 (COX1)   09164 Neurodegenerative disease    05010 Alzheimer disease     804835 (COX1)    05012 Parkinson disease     804835 (COX1)    05014 Amyotrophic lateral sclerosis     804835 (COX1)    05016 Huntington disease     804835 (COX1)    05020 Prion disease     804835 (COX1)    05022 Pathways of neurodegeneration - multiple diseases     804835 (COX1)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     804835 (COX1)   09167 Endocrine and metabolic disease    04932 Non-alcoholic fatty liver disease     804835 (COX1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03029 Mitochondrial biogenesis [BR:uar03029]     804835 (COX1) Enzymes [BR:uar01000]  7. Translocases   7.1  Catalysing the translocation of protons    7.1.1  Linked to oxidoreductase reactions     7.1.1.9  cytochrome-c oxidase      804835 (COX1) Mitochondrial biogenesis [BR:uar03029]  Mitochondrial DNA transcription, translation, and replication factors   Mitochondrial DNA-encoded proteins    Cytochrome c oxidase     804835 (COX1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  COX1 Motif Other DBs NCBI-GeneID:  804835 NCBI-ProteinID:  NP_597957 UniProt:  Q8SJJ7 LinkDB All DBs Position MT AA seq 514 aa AA seqDB search MFMNRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGALLGDDQIYNVIVTA HAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEA GAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGISSILGAINFITTIINMKPPAMSQYQ TPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGH PEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVD TRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLAN SSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNNTWAKIHFMIMFVG VNMTFFPQHFLGLSGMPRRYSDYPDAYTTWNTVSSMGSFISLTAVMLMIFMIWEAFASKR EVAVVELTSTNIEWLHGCPPPYHTFEEPTYVTLK NT seq 1545 nt NT seq  +upstreamnt  +downstreamnt atgttcataaatcgatgactgttctctacaaatcataaagatattggcactctttacctt ctgttcggtgcatgagccggaatagtaggtactgctctcagccttttaatccgtgccgag ctaggtcagcccggggctctgttgggggatgatcaaatctacaatgtaatcgtaactgcc catgcattcgtaataatcttctttatggtcatgcctattataattgggggatttgggaac tgattagtacccttaataattggtgcccccgacatagcatttcctcgaataaataatata agtttctgactgctgccaccatctttcttattgctcctagcctcttctatagtagaagca ggggcagggactggatgaactgtctacccccctctagcgggtaatctggcccatgcaggg gcatcagtagacttaacaatcttttctctacacttagcaggtatctcttctattctagga gctatcaatttcatcactactattatcaacatgaagccccctgcaatgtctcaatatcaa acccccctgtttgtatgatcagtcctaattacggcagtgcttcttcttttatctctgcca gtcttagcagctggaattaccatactacttacagatcgaaaccttaataccacctttttt gacccagccggaggaggagaccctattctatatcaacacttgttttgattcttcggacac cctgaagtttatatcctaattcttccagggttcggaatgatctctcacattgtcacttat tactcaggaaaaaaagagcctttcggctatataggaatagtctgagcgataatgtctatt ggattcttaggatttatcgtgtgagctcaccatatgtttaccgtaggtatagatgtcgac acacgagcttacttcacttcagccaccataattattgcaatcccaacaggggttaaagta tttagctgattagccaccctacacggagggaatattaaatgatctcccgctataatatga gccctaggctttattttcctgtttacagtggggggccttacaggaattgtcctagctaac tcatctctagatattgttcttcatgatacatactatgtggtagctcatttccactatgtg ttatcaatgggggctgtctttgccattatggggggatttgtgcattgattcccactgttt tcaggctatacgcttaataatacatgagcaaaaattcacttcataatcatgttcgtaggg gttaatatgacattctttccccagcattttctaggcctgtcaggaatacctcggcgatac tccgactatccggatgcctatacaacatgaaatacagtatcttctataggctcattcatt tcactaacagcagttatactaataatttttatgatttgggaggcctttgcatcaaaacga gaggtggcagtggtagaactcacttcaaccaacattgagtggctacatggatgtcctcct ccatatcacacatttgaagaacccacttacgttacactaaaataa

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