Ursus maritimus (polar bear): 103656463
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Entry
103656463 CDS
T03271
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr00260
Glycine, serine and threonine metabolism
umr00630
Glyoxylate and dicarboxylate metabolism
umr00670
One carbon pool by folate
umr01100
Metabolic pathways
umr01200
Carbon metabolism
umr01230
Biosynthesis of amino acids
umr01240
Biosynthesis of cofactors
umr01523
Antifolate resistance
umr04981
Folate transport and metabolism
Module
umr_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
103656463 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
103656463 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
103656463 (SHMT2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
103656463 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
103656463 (SHMT2)
Enzymes [BR:
umr01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
103656463 (SHMT2)
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Ortholog
Paralog
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Motif
Pfam:
SHMT
Motif
Other DBs
NCBI-GeneID:
103656463
NCBI-ProteinID:
XP_008682075
UniProt:
A0A452UYK5
A0A384BIV1
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All DBs
Position
Unknown
AA seq
504 aa
AA seq
DB search
MLPFSLLWATRPLQRCGQLVRMAIRCQHSEVAQTQTGEATRGWTGQESLSDSDPEMWELL
QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGTEVVDEVELLCQ
RRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
KRVSATSIFFESMPYKLNPKTGLIDYDQLALTARLFRPRLIIAGTSAYARLIDYARMREV
CDEVRAHLLADMAHISGLVAAKVIPSPFKHADVVTTTTHKTLRGARSGLIFYRKGTRAVD
PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYALQVLKNARA
MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVSIGLAVKSKTAKLQDFKSFLLKDPETSH
RLADLRQRVEQFARAFPMPGFDER
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atgctgcccttctctttgctctgggcgactcggcctctgcagagatgtggtcagctggtc
aggatggccatccggtgccagcacagtgaggtggcccagacccagactggagaagcaacc
aggggctggacaggccaggagagtctgtcagacagtgaccctgagatgtgggagctgctg
cagagggagaaggacaggcagtgtcgtggcctggagctcattgcctcagagaacttctgc
agccgagctgcgctggaggccctggggtcctgtctgaacaacaagtactcggagggttat
cctggcaagaggtactacggaggcacagaggtagtggatgaagttgagctgctgtgtcag
cgcagggccttagaggccttcgacctggatcccgcgcagtggggagtcaatgtgcagccg
tactcgggctcgccggctaatctggccgcctacacggccctcctgcagccccatgaccga
atcatggggctggacttgcccgatgggggccatctgactcacggctacatgtctgatgtc
aagcgggtctcagccacgtccatcttctttgagtccatgccctataagctcaatcctaaa
accggcctcatcgactacgaccagctggcgctgactgcgcggctcttccgcccgcggctc
attattgctggtaccagtgcctacgcgcgcctcattgactacgcccgcatgagagaggtg
tgtgatgaagtcagggcacacctactggcagacatggcccacatcagtggcctggtggct
gccaaggtgatcccctcacctttcaagcatgcggatgttgtcaccaccaccactcacaag
acccttcgaggggccaggtctggactcatcttctaccggaaggggactcgggctgtggac
cccaagactggccgggagatcccgtacacatttgaggaccgaatcaactttgccgtgttc
ccatccctgcagggggggccccacaaccatgccattgctgccgtggctgtggccctaaag
caggcctgcacccccatgttccgggagtacgccctgcaggttctgaagaatgctcgggcc
atggctgatgccctgctagagcgaggctactcgctcgtgtctggtggcaccgacaaccac
ctagtgctcgtggatctgcggcccaagggcctggatggagctcgggctgagcgggtgctg
gaactggtgtccatcacagccaacaagaacacctgtcctggagaccgaagtgccatcaca
cctgggggcctgcggctcggggccccagccctgacctctcgacagttccgcgaggatgac
ttccggagagttgtggacttcatagatgaaggtgtcagcatcggcttggcggtgaagagc
aagactgccaaactccaggatttcaaatccttcctgctcaaggacccagaaacaagtcat
cggctggctgacctcaggcaacgggtggagcagtttgccagggccttccccatgcctggt
tttgatgagcgctga
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