KEGG   Ursus maritimus (polar bear): 103656766
Entry
103656766         CDS       T03271                                 
Symbol
GSTO1
Name
(RefSeq) glutathione S-transferase omega-1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr00480  Glutathione metabolism
umr00980  Metabolism of xenobiotics by cytochrome P450
umr00982  Drug metabolism - cytochrome P450
umr00983  Drug metabolism - other enzymes
umr01100  Metabolic pathways
umr01524  Platinum drug resistance
umr05200  Pathways in cancer
umr05204  Chemical carcinogenesis - DNA adducts
umr05207  Chemical carcinogenesis - receptor activation
umr05208  Chemical carcinogenesis - reactive oxygen species
umr05225  Hepatocellular carcinoma
umr05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:umr00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    103656766 (GSTO1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    103656766 (GSTO1)
   00982 Drug metabolism - cytochrome P450
    103656766 (GSTO1)
   00983 Drug metabolism - other enzymes
    103656766 (GSTO1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103656766 (GSTO1)
   05204 Chemical carcinogenesis - DNA adducts
    103656766 (GSTO1)
   05207 Chemical carcinogenesis - receptor activation
    103656766 (GSTO1)
   05208 Chemical carcinogenesis - reactive oxygen species
    103656766 (GSTO1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    103656766 (GSTO1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    103656766 (GSTO1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    103656766 (GSTO1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:umr02000]
    103656766 (GSTO1)
Enzymes [BR:umr01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     103656766 (GSTO1)
Transporters [BR:umr02000]
 Other transporters
  Pores ion channels [TC:1]
   103656766 (GSTO1)
SSDB
Motif
Pfam: GST_N_2 GST_N_3 GST_N GST_C_3 GST_C CLIC-like_N GST_C_2 Glutaredoxin Zona_CL2
Other DBs
NCBI-GeneID: 103656766
NCBI-ProteinID: XP_040479880
UniProt: A0A8M1FCD4
LinkDB
Position
Unknown
AA seq 241 aa
MSGGSARSLGKGSAPPGPVPEGLIRVYSMRFCPFAQRTRLVLKAKGIRHEIININLKNKP
EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKAYQKMVFELF
SKIPSLVASFLRRQNEEDCSGLKEELRKEFSKLEEVLTNKKTTFFGGNSVSMIDYLIWPW
FERLEVLELNDCADHTLELKLWMAAMREDPAVSALLTEPKVFRGFLSLYLQNSPDACDYG
L
NT seq 726 nt   +upstreamnt  +downstreamnt
atgtccggagggtcggccaggagcctagggaagggaagcgcgcccccgggaccggtcccc
gagggcctgatccgcgtctacagcatgaggttctgcccgttcgcgcagaggacacgcctg
gtcctgaaggccaagggaatcaggcatgaaatcatcaacatcaacctgaaaaataagcct
gagtggttctttaagaagaatccctttggcctggtgccagttctggaaaacagtcagggt
caactgatctacgaatctgccatcacttgtgagtacctggatgaagcctatcccgggaag
aagctgttgccagacgacccctatgagaaagcttaccaaaagatggtgttcgagttattt
tcgaagattccatctttggtagcaagctttctgagaagacaaaatgaggaagactgctct
ggcctaaaagaagaattgcggaaagaattcagcaagcttgaggaggttcttaccaataag
aagacaaccttctttggtggcaattctgtttctatgattgattacctcatctggccctgg
tttgaacggctggaagttctggagttaaatgattgtgcagaccacactcttgaacttaag
ctctggatggcagccatgagggaagatcctgcagtgtcagccctcctcactgagcccaag
gtctttcgaggtttcctcagtctctatttgcagaacagccccgacgcctgtgactatggg
ctctga

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