| Entry |
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| Symbol |
ABCC4
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| Name |
(RefSeq) multidrug resistance-associated protein 4
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| KO |
| K05673 | ATP-binding cassette, subfamily C (CFTR/MRP), member 4 |
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| Organism |
umr Ursus maritimus (polar bear)
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| Pathway |
| umr04981 | Folate transport and metabolism |
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| Brite |
KEGG Orthology (KO) [BR:umr00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
103657592 (ABCC4)
09132 Signal transduction
04024 cAMP signaling pathway
103657592 (ABCC4)
09150 Organismal Systems
09154 Digestive system
04976 Bile secretion
103657592 (ABCC4)
04981 Folate transport and metabolism
103657592 (ABCC4)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
103657592 (ABCC4)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:umr02000]
103657592 (ABCC4)
Transporters [BR:umr02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
103657592 (ABCC4)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
1495 aa
MRAASPEGSSGLAALPGVLKAAAQGAFPSSWVGRVSASPPQLLLGALERGLLQSLQPGKS
TWALRTTSSARPPSSNAGGGLASYLHGVRAAWSPPPTSGRLASGASLQAPGSRFPAAGAA
RPGGRERGGPPALSSRKRVVLGLPPRGPARPPLLQHPRPRLREQRDPGGKMLPVYAEVKP
NPLQNANLCSRVFFWWLNPLFKIGHKRRLEEDDMYSVLPEDRSKHLGEELQGYWDKEVSR
AEKDSRKPSLTKAIIKCYWKSYLVLGIFTLIEEGIKVIQPIFLGKIINYFENHDSTSSVA
LHEAYAYTTALAVCTLILAIMHHLYFYHVQCAGMRLRVAMCHMIYRKGLRLSNRAMGKTT
TGQIVNLLSNDVNKFDQVTIFLHFLWAGPLQAIAVTALLWMEIGISCLAGIAVLIILLPL
QSCLGKLFSSFRSKTATFTDTRIRTMNEVITGIRIIKMYAWEKSFADLITHLRRKEISKI
LSSSYLRGMNLASFFVASKIIVFVTFTTYVFLGNVITASRVFVALSLYGAVRLTVTLFFP
TAIEKVSEAVVSIQRIKNFLLLDEVSQRPPQLPSDGKMIVHVQDFTAFWDKASETPTLQG
LSFTVRPGELLAVIGPVGAGKSSLLSAVLGELPRSHGLVSVHGRIAYVSQQPWVFSGTVR
SNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGATLSGGQKARVNLARAVY
QDADIYLLDDPLSAVDAEVGRHLFELCICQTLHEKITILVTHQLQYLKAASQILILKDGR
MVQKGTYTEFLKSGVDFGSLLKRENEEADQSPAPGSPALRTRSFSASSVWSQQSSRPSLK
DGAPEAQANENTQVALSEESRSEGKVGFKAYKNYLTAGAHCLVIVFLILLNIVAQVAYVL
QDWWLSYWANEQSALNVTVNGKENVTEKLDLAWYLGIYSGLTVATVLFGIARSLLVFYVL
VHSSQTLHNKMFESILRAPVLFFDRNPVGRILNRFSKDVGHMDDLLPLTFLDFFQTFLQV
LGVVGVAVAVIPWIAIPLIPLGILFFVLRRYFLETSRDVKRLESTTRSPVFSHLSSSLQG
LWTIRAYKAEERFQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAIFVVVVAFGSLIL
AKTVDAGQVGLALSYALTLMGMFQWCVRQSAEVENMMISVERVLEYTDLEKEAPWEYQNR
PPPNWPQDGTIVFDNVNFTYSLDGPLVLKHLTVLIKSREKVGIVGRTGAGKSSLISALFR
LSEPEGRIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFNEHTDEELWNAL
TEVQLKEAIEDLPGKLDTELAESGSNFSVGQRQLVCLARAILRKNRILIIDEATANVDPR
TDELIQKKIREKFAQCTVLTIAHRLNTIIDSDKIMVLDSGRLKEYDEPYVLLQNEESLFY
KMVQQLGKAEAAALTETAKQVYFKRNYPDITHSDHVVMNASNGQPSAFTIFETAL |
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| NT seq |
4488 nt +upstreamnt +downstreamnt
atgagggcagcaagcccagaaggctcaagtggtctggctgctctcccaggtgttctgaaa
gccgcggcccagggggcgtttccgagcagctgggtgggcagggtcagcgcctcccctccg
cagcttcttctgggtgccctggagcggggacttctgcaaagtttgcagccaggtaagagc
acgtgggccctgcggaccacgagctctgcccgcccgccttcatctaacgccggcggcggc
ctcgcctcgtacctgcacggggtacgggcagcgtggtctccaccgcccacgtccggccgc
ctcgcaagcggcgcgtcgctccaggctccaggctccaggttcccggcggcaggagccgcg
cggccgggggggcgggaacggggcgggccgccggcgctcagctcccggaagcgggtggtt
cttgggctcccgcccagaggaccggcgcggccgccgctgctccagcatccccgcccgcgt
ctccgggagcagcgcgaccccggcggcaagatgctgcccgtgtacgcggaggtgaagccc
aacccgctgcagaacgcgaacctctgctcgcgcgtgttcttctggtggctgaaccccttg
tttaaaattggtcacaaacggagattagaagaagatgacatgtattcggtgcttccagaa
gatcgctcaaagcatctgggagaagagttgcaagggtactgggataaagaagtttcgagg
gccgagaaagactcacggaagccttctttaacaaaagcgatcataaagtgttactggaaa
tcctatttagttttgggaatttttacgctcattgaggaaggcatcaaagtaatccagccc
atatttttggggaaaattattaattattttgaaaaccatgattccactagttctgtggct
ttgcacgaagcctacgcctataccacggcgctggccgtctgcacactcatcctggccatc
atgcatcatttatacttctatcatgttcagtgcgccggcatgaggctgcgagtcgccatg
tgccatatgatttatcggaaggggcttcgccttagtaacagggccatggggaagacgacc
accggccagatcgtgaatctgctgtccaatgacgtgaacaagtttgaccaggtgacaata
ttcttgcactttctgtgggcagggccactgcaagcgatcgcagtgaccgccttgctctgg
atggaaataggcatatcctgtcttgctgggatcgccgttctaattattcttctacccttg
caaagctgcctcgggaagctgttttcatcattccggagtaagaccgcaactttcacggac
accaggatcaggaccatgaatgaagtgataactggcataagaataataaaaatgtatgct
tgggaaaagtcatttgcagaccttatcacccatttgagaaggaaggaaatttccaagatt
ctgagcagttcctacctcagaggaatgaatttggcatcatttttcgttgcaagcaaaatc
atcgtttttgtgactttcaccacctatgtgtttcttggcaatgtgatcacagccagccgt
gtgttcgtcgcactgtcgctctacggggctgtgcggttgactgttaccctcttcttcccc
acggccattgagaaggtgtccgaggcagtcgtcagcatccaaagaatcaagaactttctg
ttactggacgaggtctcacagcgcccccctcagctgccgtcagatggtaaaatgatagtg
cacgtgcaggacttcactgccttttgggataaggcgtcagaaaccccaaccctacaaggc
ctttcctttactgtgagacccggggaattgttagctgtgatcggaccggtgggagcagga
aagtcctcactgttaagtgccgttctgggggagctgccccggagccacgggctggtcagc
gtgcatggaaggatcgcctacgtttctcagcagccctgggtgttttcaggaactgtgagg
agtaacattttatttgggaagaaatatgaaaaggaacgatacgaaaaagtaataaaggct
tgtgctttgaaaaaggatttgcagcttttggaggacggagatttaaccgtgataggcgat
cggggagccacgctgagcggagggcagaaggcccgggtcaacctcgcaagagcggtgtat
caggacgcagacatctacctcctggacgatcctctcagtgcggtagatgcagaagtcggc
aggcacttgtttgaactgtgtatttgccaaaccttgcatgagaagatcacaatcttagtg
actcatcagttgcagtacctaaaagctgcaagtcagattctgatattgaaagatggcaga
atggtgcagaaggggacttacacggagtttctaaaatccggggtagatttcggctccctt
ttaaagagggaaaacgaggaggctgaccagagtccggctccaggatctcctgctctgagg
actcggagcttctcagcgtcttctgtttggtcccagcagtcgtcccgaccgtcactgaaa
gatggtgcgccagaggcgcaagctaacgagaatacacaggttgctctgtcagaggagagt
cgttcggaaggaaaagtcggttttaaggcctacaagaattacctaacagccggtgcgcac
tgcttggtcattgtgttcctcattctgctgaacatcgtagctcaggttgcctatgttctt
caggactggtggctctcctactgggcgaatgaacaaagtgccctgaatgtcacagtaaat
ggaaaagaaaatgtcactgagaagctcgatcttgcctggtacttaggaatttattcaggt
ctaactgtggctactgtcctctttggcatagcaagatctctgttggtgttctacgtcctc
gttcattcttcacaaactttgcacaacaaaatgttcgagtccattttgagagctccggtg
ttgttcttcgatagaaacccagtaggaagaattttaaatcgtttctccaaagacgttggg
cacatggatgacttgctacccctgacgtttctagatttcttccagacatttctacaagtt
ttgggtgtggtgggcgtggcagtggccgtgatcccgtggattgcaatacctctaattccc
ctgggcatccttttctttgttcttcggcggtatttcttagaaacttcaagagatgtcaaa
cgcctggaatctacaacacggagtccggtattctcccacttgtcgtcctctctccaggga
ctctggaccatccgggcatataaagctgaagagaggttccaggaactgttcgacgcacac
caggatttgcattcagaggcctggttcttgttcctgacgacatcccgctggttcgctgtg
cgtctggacgccatctgcgccatctttgtcgttgttgttgccttcgggtccctgattctg
gcaaaaactgtagatgctgggcaggttggcctggcattgtcctacgccctcacactcatg
gggatgttccagtggtgcgtcaggcaaagcgccgaagtggagaatatgatgatttcagtg
gaaagggtgttggagtacacagatcttgagaaagaagctccttgggaataccagaaccgt
cctccaccaaactggccccaggacggcacgattgtctttgataatgttaacttcacgtac
agtttagacgggcctctggttttgaagcacctgacagtgctcattaaatcaagggaaaag
gttggcattgtgggaagaacaggagctgggaagagttccctcatctcggccctttttaga
ttgtcagaaccggaaggtagaatttggattgataagatcttgacaactgaaattgggctt
cacgatctaaggaagaaaatgtccatcatacctcaggaacctgttttattcactggaaca
atgaggaaaaatctggatccctttaacgagcatacagatgaggaactgtggaatgcctta
acggaggtacagcttaaagaagccattgaagatcttcctggcaaattggacaccgaatta
gcagaatcaggatcgaatttcagtgtgggacagagacagttggtgtgcctcgccagggcc
atcctcaggaaaaaccggatattgatcattgacgaagcaacagcaaatgtggacccaaga
actgacgaattaatacaaaaaaaaatccgtgagaaatttgcccagtgcaccgtgctaacc
attgcacacaggttgaataccattattgacagcgacaagatcatggttttggattcagga
agactgaaagaatatgatgaaccgtatgttttgctgcagaatgaagagagcctattttac
aagatggtgcagcagctgggcaaggcagaagctgctgccctcactgaaacagcaaaacag
gtgtacttcaaaaggaattatccagatattactcacagtgaccatgtggttatgaatgct
tccaatggacagccctcagcctttactatttttgagacagccctgtga |
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