KEGG   Ursus maritimus (polar bear): 103658669
Entry
103658669         CDS       T03271                                 
Symbol
HGF
Name
(RefSeq) hepatocyte growth factor isoform X2
  KO
K05460  hepatocyte growth factor
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr01521  EGFR tyrosine kinase inhibitor resistance
umr04010  MAPK signaling pathway
umr04014  Ras signaling pathway
umr04015  Rap1 signaling pathway
umr04020  Calcium signaling pathway
umr04151  PI3K-Akt signaling pathway
umr04510  Focal adhesion
umr05144  Malaria
umr05200  Pathways in cancer
umr05205  Proteoglycans in cancer
umr05208  Chemical carcinogenesis - reactive oxygen species
umr05211  Renal cell carcinoma
umr05218  Melanoma
umr05223  Non-small cell lung cancer
umr05225  Hepatocellular carcinoma
umr05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:umr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103658669 (HGF)
   04014 Ras signaling pathway
    103658669 (HGF)
   04015 Rap1 signaling pathway
    103658669 (HGF)
   04020 Calcium signaling pathway
    103658669 (HGF)
   04151 PI3K-Akt signaling pathway
    103658669 (HGF)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    103658669 (HGF)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103658669 (HGF)
   05205 Proteoglycans in cancer
    103658669 (HGF)
   05208 Chemical carcinogenesis - reactive oxygen species
    103658669 (HGF)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    103658669 (HGF)
   05226 Gastric cancer
    103658669 (HGF)
   05218 Melanoma
    103658669 (HGF)
   05211 Renal cell carcinoma
    103658669 (HGF)
   05223 Non-small cell lung cancer
    103658669 (HGF)
  09174 Infectious disease: parasitic
   05144 Malaria
    103658669 (HGF)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    103658669 (HGF)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:umr04052]
    103658669 (HGF)
   00536 Glycosaminoglycan binding proteins [BR:umr00536]
    103658669 (HGF)
Cytokines and neuropeptides [BR:umr04052]
 Cytokines
  Growth factors (RTK binding)
   103658669 (HGF)
Glycosaminoglycan binding proteins [BR:umr00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   103658669 (HGF)
SSDB
Motif
Pfam: Kringle Trypsin PAN_1 DUF1986 DUF316 CWC25
Other DBs
NCBI-GeneID: 103658669
NCBI-ProteinID: XP_008684406
UniProt: A0A452UEJ7 A0A384BP91
LinkDB
Position
Unknown
AA seq 730 aa
MWGTKLLPVLLLQHVLLHLLLLPIAIPYAEGQKKRRNTLHEFKKSAKTTLIKEDPLLKIK
TKKMNTADQCANRCIRNKGLPFTCKAFVFDKARKRCLWFPFNSMTSGVKKDFGHEFDLYE
NKDYIRNCIIGKGGSYKGTVSITKSGIKCQPWNSMIPHEHSFLPSSYRGKDLQENYCRNP
RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGPMDHTESGKICQRWDHQTP
HRHKFLPERYPDKGFDDNYCRNPDGKPRPWCYTLDPDTPWEYCAIKMCAHSTMNDTNVPM
ETTECIHGQGEGYRGTINTIWNGIPCQRWDSQYPHQHDITPENFKCKDLRENYCRNPDGA
ESPWCFTTDPNIRVGYCSQIPKCDVSSGQDCYRGNGKNYMGNLSKTRSGLTCSMWEKNME
DLHRHIFWEPDASKLNKNYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNL
DHPVISCAKTKQLRVVNGIPTRTNVGWMVSLKYRNKHICGGSLIKESWILTARQCFPSRN
KDLKDYEAWLGIHDVHGKGDEKRKQVLNVSQLVYGPEGSDLVLLKLARPAVLDDFVSTID
LPNYGCTIPEKTTCSVYGWGYTGSINSDGLLRVAHLYIMGNEKCSQYHQGKVTLNESEIC
AGAENIVSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHK
IILTYKIPQS
NT seq 2193 nt   +upstreamnt  +downstreamnt
atgtgggggaccaaacttctgccagtcctgctgctgcagcatgtcctcctacatctgctt
ctgcttcccatcgccatcccctatgcagaaggacagaagaaaagaagaaacacacttcat
gaattcaaaaagtcagcaaagactactctaattaaagaagacccattactgaagataaaa
acaaaaaaaatgaacactgcagaccaatgtgccaatagatgtattaggaataaaggactt
ccattcacttgcaaggcctttgtttttgataaagcaaggaaaagatgcctctggttccct
ttcaatagcatgacaagtggcgtgaaaaaagactttggtcatgaattcgacctctatgaa
aacaaagactacattagaaactgcatcattggtaaaggaggtagctacaagggaacggta
tctatcactaagagtggcatcaaatgccagccctggaattccatgatcccacatgaacac
agctttttgccttcgagctatcggggtaaagacctacaggaaaactactgtcgaaatcct
cgaggggaagaagggggaccttggtgtttcacaagcaatccagaggtacgctacgaagtc
tgtgacattcctcagtgttccgaagttgaatgcatgacctgcaatggggaaagttatcga
ggtcccatggatcatacagaatcaggcaagatttgtcagcgctgggatcatcagacacca
caccggcacaaattcttgccagaaagatatcccgacaagggctttgatgataattattgc
cgcaatcctgatggcaaaccgaggccatggtgctatactcttgaccctgacaccccctgg
gagtactgtgcaattaaaatgtgcgctcacagtactatgaatgacacaaatgtccctatg
gaaacaactgaatgcattcatggtcaaggagaaggttaccggggcaccatcaatactatt
tggaatggaattccatgtcagcgttgggattcccagtatcctcaccagcatgacataact
cctgaaaatttcaagtgcaaggacctaagagaaaattattgccgaaatccagatggggct
gagtcaccctggtgttttaccactgatccaaacatccgagttggctactgctcccaaatt
ccaaaatgtgatgtgtcaagtggacaagattgttatcgtgggaatggcaaaaattatatg
ggcaatttatccaaaactcgatctggactaacatgttcaatgtgggagaagaacatggaa
gacttacacaggcatatcttctgggaaccagatgctagtaagctgaataagaattactgc
cggaatcctgatgatgatgcccatggtccctggtgttacacaggaaatcctctcattcca
tgggattattgtcctatttctcgttgtgaaggtgataccacacctacaatagtcaattta
gaccatcctgtaatatcttgtgccaaaacgaaacaattaagagttgtaaatggaattcca
acgcgaactaatgtaggatggatggttagtttgaaatacagaaataaacatatctgtgga
ggatcattgataaaggaaagttggattcttaccgcaagacaatgtttcccttctcgaaac
aaagacttgaaagattatgaagcttggcttgggattcatgatgtccacggaaaaggagac
gagaaacgcaaacaagttctaaatgtttcccagctggtatatggacctgaaggatcagat
ctggtattactgaagcttgctaggcccgctgtcctggatgattttgttagtacaattgat
ttacctaattatggatgcaccattcctgaaaaaaccacttgcagtgtttatggctggggt
tatactggatccatcaactctgatggtctattacgagtagcacatctctatattatggga
aatgagaaatgcagccaataccatcaagggaaggtgactctgaatgagtctgaaatatgt
gctggagctgaaaatattgtatcaggaccatgtgagggagattatggtggcccacttgtt
tgtgaacaacataaaatgagaatggttcttggtgtcattgttcctggtcgtggatgtgcc
ataccaaatcgtcctggcatttttgtccgagtagcatattacgcaaaatggatacacaaa
attatattaacgtataagataccacagtcatag

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