| Entry |
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| Symbol |
ABCC3
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| Name |
(RefSeq) ATP-binding cassette sub-family C member 3
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| KO |
| K05667 | ATP-binding cassette, subfamily C (CFTR/MRP), member 3 |
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| Organism |
umr Ursus maritimus (polar bear)
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| Pathway |
| umr04981 | Folate transport and metabolism |
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| Brite |
KEGG Orthology (KO) [BR:umr00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
103660879 (ABCC3)
09150 Organismal Systems
09154 Digestive system
04976 Bile secretion
103660879 (ABCC3)
04981 Folate transport and metabolism
103660879 (ABCC3)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
103660879 (ABCC3)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:umr02000]
103660879 (ABCC3)
Transporters [BR:umr02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
103660879 (ABCC3)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
1622 aa
MQRLRSRDDLDLTRDIFTEDVLLSHFPQLYDLLARQSYASWTRTLLQPHQPQYLEGHLSG
AAHWPLEGVVTVSAALHAPGPKSLLEPQSQGGSVAIRKDKEIPPKEPKDSNLSVHTDNPD
LTPCFQNSLLAWAPCVYLWAALPCHLLYLRHHDRGYIVLSHLSRLKTAVGVLLWCVSWAD
LFYSFHGLVHGWAPAPIFFITPLVVGITMLLATLLIQYDRLRGVQSSGVLIIFWFLCVVC
AIVPFRSKILSAMAKGKIADPFRFTTFYVSFALLLFALILSCFREKPPFFSPKNVNPNPC
PELSAGFLSRLSFWWFTKMAILGYRRPLEEQDLWSLKEDDCSQKLVQGLLEEWKKLQEQA
KRDEAAAASGTRASEEDEVLLRGRARPRQPSFLRALLATFSSTLLISIGLKVIQDLLSFV
NPQLLSILIRFISNPMAPAWWGFLVAGLMFSCSMMQTLILHQYYHLIFVSALKLRMAITG
VIYRKALVITNSAKRESSVGEIVNLMSVDAQRFMDLAPFLNLMWSAPLQIILAIYFLWQN
LGPSILAGVALMVLLIPLNGAVAMKMRALQVEQMKFKDSRIKLMSEILAGIKVLKLYTWE
PSFSEKVEGIREDELRLLRKSAYLQAISTFTWVCTPFLVTLTTLGVYVSVDPNNVLDAEK
AFVSVSLFNILKIPLNMLPQLISSLIQTSVSLKRIQHFLSQDELDPQCVERKTITPGYAV
TIHNGTFTWAQDLPPTLHSLDIQVPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGTVCV
KGSVAYVPQQAWIQNCTLQENILFGRALDPKRYQRALETCALLADLEMLPGGDKTEIGEK
GINLSGGQRQRVSLARAVYSEADLFLLDDPLSAVDSHVAKHIFDQVIGPEGVLAGKTRVL
VTHGISFLPQMDFIIVLADGQVSEVGSYPGLLQRNGSFANFLCNYAPEEDKESLKEDSRT
ALEDTENEGVLLIEDTLSNHTDLTDNEPVMYEVQKQFMRQLSVMSSEGEGQGRPVPRRRL
GSAENRVQAEEAKARGKLIQEEEAEMGTVKLSVLWDYAKAMGFYTTVAICVLYPGQTAAA
IGANVWLSAWTNEAMADSRQNSTSMRLGVYAALGILQGLLVMLAAITLTVGSVHAARTLH
RALLHNNMRLPQSFFDTTPSGRILNRFSKDVCVIDEALAPTILMLLNSFYNSLATLVVIV
ASTPLFTVVTLPLAVFYVLMQRFYVATSRQLKRLESISRSPIYSHFSETVTGSSVIRAYG
RSQDFKAISDAKVDANQKSCYAYIASNRWLGVQVEFVGNCVVLFAALFAVIGRNNLSPGL
VGLSVSYALQITLTLNWMIRMMSELESNLVAVERVKEYSKTETEAPWVVEGSRPPAGWPL
QGEVEFRNYSMRYRPGLELVLKNLSLRVRGGEKVGIVGRTGAGKSSMTLCLFRILEAAEG
EIRIDGLNVADIGLHDLRSQLTIIPQDPILFSASLRMNLDPFGRYSEEDIWRALELSHLH
TFVSSQPAGLDFQCSEGGENLSVGQRQLVCLARALLRKSRILVLDEATAAIDLETDNFIQ
ATIRTQFESSTVLTIAHRLNTIMDYTRILVLDKGTIAEFDSPANLIAARGIFYTMARDAG
LA |
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| NT seq |
4869 nt +upstreamnt +downstreamnt
atgcaaagactgaggtccagagatgaccttgacctcaccagggatatattcacggaggac
gtcttgctaagtcactttccacagctctatgacttattggcccgtcagagttatgcctct
tggacacggaccctgctccagccccatcagcctcagtatctggagggacatctttccggc
gctgcccactggccactcgaaggagtcgtcactgtatcagcggctctccacgctcctggc
ccaaagtccctcctggagccgcagtctcagggaggctctgtcgcaattcgcaaggacaaa
gagattccacccaaagagccaaaggactccaatctgtctgtgcacaccgacaacccggac
ctcactccctgcttccagaactccctgctggcctgggcgccctgcgtctatctgtgggcc
gccctgccctgccacctgctctatctgcggcaccatgaccgaggctacatcgtcctctcc
cacctctccaggctcaagacggccgtgggcgtcctgctgtggtgcgtctcctgggctgac
ctcttctactccttccacggcctggtccatggctgggcccctgccccaatcttctttatc
acccccttggtggtggggatcaccatgctgctggccaccctgctaatccagtatgaccgg
ctgcggggggtacagtcctcaggggtcctcatcatcttctggtttctgtgtgtggtctgt
gccattgtccccttccgctccaagatcctttcggccatggcaaagggcaagatcgcagac
cccttccgcttcaccaccttctatgtctccttcgccctgctgctctttgcactcatccta
tcctgcttcagggagaagccgccatttttctccccaaagaatgtcaaccccaatccctgc
ccggaactcagtgccggcttcctctcccgcctgtctttctggtggttcacaaagatggcc
atccttggctaccggcgccccctggaggagcaggacctctggtccctgaaggaggacgac
tgttcgcagaagttggtgcaggggctgctggaggagtggaagaagcttcaggagcaggcc
aagcgagacgaggctgcggcggcatctgggacgagagcgtccgaggaagatgaggtgctg
ctgaggggccgggccaggccccggcagccctccttcctgcgggccctgctggccaccttc
tcttctaccctcctcatcagcataggcctcaaggtgatccaggacctgctgtccttcgtc
aacccacagctgctcagcatcctaatcaggtttatctccaaccccatggcccccgcctgg
tggggcttcctggtggccgggctgatgttctcatgctccatgatgcagactctgatctta
caccagtattaccacttaatctttgtgtcggcgttgaaacttcgtatggcgatcacaggt
gtcatctatcggaaggccctggttatcaccaattcagccaaacgggagtcctctgtggga
gaaattgtcaacctcatgtctgtggacgcccagcgcttcatggacctcgctcccttcctc
aacctgatgtggtccgcacccctgcagattatcctggccatctacttcctctggcagaac
ctgggtccctccatcttggcgggggtggctctcatggtcttgctgatcccactcaatgga
gctgtggccatgaagatgcgtgctttacaggtagagcaaatgaagttcaaggactcgcgc
atcaagctgatgagtgagatcctagctggcatcaaggtgctgaagctgtatacctgggag
cccagcttctcggagaaggtagagggcatccgcgaggacgagctccggctgctgcgcaag
tctgcgtacctccaagccatctccaccttcacctgggtctgcacccccttcctggtgacc
ctgaccacccttggggtgtatgtgtctgtggacccaaacaatgtgctggatgctgagaag
gcctttgtgtccgtgtccctgttcaatattttaaagattcccctcaacatgctgccccaa
ttaatcagcagcctgatccagaccagtgtgtctctgaaaaggatccagcatttcctgagc
caagatgaacttgacccccagtgtgtggaaagaaagaccatcaccccaggctatgctgtc
accatacacaatggcaccttcacctgggcccaggacctgccccctaccctgcacagccta
gacatccaagtgccaaaaggggcactggtggccgtggtggggcccgtgggctgtgggaag
tcctccctggtgtctgccctgctgggagagatggagaaactggaaggcacggtgtgtgtg
aagggctccgtggcctacgtgccccagcaggcctggatccagaactgcacgcttcaggaa
aacatcctgttcggccgagccctggaccccaagaggtaccaacgggctctggaaacctgt
gccttgctagctgacctggagatgctgcctggcggggacaagacagagattggagagaag
ggcattaacctgtctgggggccagcgacagcgggtcagtctggcccgagctgtttacagt
gaagctgatctttttttgctggatgacccactgtcagctgtggactctcacgtggccaag
catatctttgaccaagtcattgggccagaaggtgtgctggcaggcaagacgcgggtgctg
gtgacacacggcatcagcttcctgccccagatggacttcatcatagtgctggctgatggg
caggtgtctgaggtgggctcctacccaggcctgctgcaacgcaatggctcctttgccaac
ttcctctgcaactatgctcctgaggaggacaaggagagcctgaaggaggacagcaggacc
gccttggaggacacagagaatgagggggtgctgctgattgaagacacgctgagcaatcac
acagacctgacggataacgagccggtcatgtatgaggtccagaagcagtttatgagacag
ctgagtgtcatgtcctcggaaggcgagggccagggccggcctgtgccccgaagacgcctg
ggttcagcagagaacagagtgcaggcagaggaggcgaaggcgagggggaagctgatccag
gaagaggaggcagagatgggcactgtgaagctgagtgtgttgtgggattatgccaaggcc
atggggttctataccacggtggccatctgcgtcctatatcctggtcaaactgcggctgcc
attggggccaacgtgtggctcagtgcctggaccaatgaggctatggcggacagccgacag
aatagcacctccatgaggctgggtgtctatgctgccctgggaattctgcaagggctcctg
gtgatgctggcagccatcacgctgacggtgggcagtgtccacgctgcacgcacgcttcac
cgggcgctgctgcacaacaacatgcgcttgccacagtccttcttcgacacaacgccctca
ggccgtatcctcaaccgcttctccaaagacgtctgcgtcatcgatgaggcgctggccccc
actatcctcatgctgctgaattccttctacaactccctcgccaccctcgtggtcatcgtg
gccagcactccgctcttcactgtggtcaccctgcccctggcggtcttctacgtcttgatg
cagcgcttctatgtggctacgtcacggcagctaaagaggctggaatccatcagccgctcg
cccatttactcccacttttcggagacggtgactggctccagcgtcattcgggcctacggc
cgcagccaggacttcaaggccatcagtgatgctaaagtggacgccaaccagaagagctgc
tacgcctacattgcctccaacaggtggctgggggtccaagtggagttcgtgggcaactgt
gttgtgctctttgctgcactctttgctgtgattggcagaaacaacctgagtccggggctg
gtgggcctttctgtgtcctatgccttacagataacattgactctgaattggatgatccga
atgatgtcagagttggagtccaaccttgtggctgtggagagagtcaaggagtactccaag
acggagaccgaggccccttgggtggtggagggcagccgccctccggcgggctggcccctg
cagggcgaggtggagttccggaactactccatgcgctaccggcccggcctggagctggtg
ctgaaaaacctgagtctgcgcgtgcgcggcggcgagaaggtggggatcgtgggccgtacg
ggggccggcaagtcgtccatgaccctctgcctgttccgcatcctggaagcggcggagggg
gaaatccgcatcgacggcctcaatgtggcagacattggcctccacgacctgcgttctcag
ctgaccatcatcccccaggaccccatcctgttctctgcatccctgcgtatgaacctggac
ccctttgggcgttactcggaggaagatatatggcgagctttggagctttcccacctgcac
accttcgtgagctcacagccggcaggcctggacttccagtgctccgagggtggggagaat
ctcagcgtgggccagcgccagctcgtgtgcctggcccgagccctgctccgcaagagccga
atcctggttttagacgaggccacagcagccatcgacctggagaccgacaacttcatccag
gccaccatccggacccagtttgagagcagcacggtgctgaccattgcccaccggctcaac
accatcatggactacaccaggatccttgtcctggacaaagggacgatagctgaatttgat
tctccagccaacctcattgcagccagaggcatcttctacacgatggccagagatgctgga
cttgcctaa |
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