KEGG   Ursus maritimus (polar bear): 103660962
Entry
103660962         CDS       T03271                                 
Symbol
ITGA3
Name
(RefSeq) LOW QUALITY PROTEIN: integrin alpha-3
  KO
K06482  integrin alpha 3
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr04151  PI3K-Akt signaling pathway
umr04510  Focal adhesion
umr04512  ECM-receptor interaction
umr04518  Integrin signaling
umr04640  Hematopoietic cell lineage
umr04810  Regulation of actin cytoskeleton
umr04820  Cytoskeleton in muscle cells
umr05165  Human papillomavirus infection
umr05200  Pathways in cancer
umr05222  Small cell lung cancer
umr05410  Hypertrophic cardiomyopathy
umr05412  Arrhythmogenic right ventricular cardiomyopathy
umr05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:umr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    103660962 (ITGA3)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    103660962 (ITGA3)
   04518 Integrin signaling
    103660962 (ITGA3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    103660962 (ITGA3)
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    103660962 (ITGA3)
   04810 Regulation of actin cytoskeleton
    103660962 (ITGA3)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    103660962 (ITGA3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103660962 (ITGA3)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    103660962 (ITGA3)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    103660962 (ITGA3)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    103660962 (ITGA3)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    103660962 (ITGA3)
   05414 Dilated cardiomyopathy
    103660962 (ITGA3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:umr04147]
    103660962 (ITGA3)
   04515 Cell adhesion molecules [BR:umr04515]
    103660962 (ITGA3)
   04090 CD molecules [BR:umr04090]
    103660962 (ITGA3)
Exosome [BR:umr04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   103660962 (ITGA3)
Cell adhesion molecules [BR:umr04515]
 Integrins
  Integrin alpha subunits
   103660962 (ITGA3)
CD molecules [BR:umr04090]
 Proteins
  103660962 (ITGA3)
SSDB
Motif
Pfam: Integrin_A_Ig_3 Integrin_A_Ig_1 Integrin_A_Ig_2 FG-GAP FG-GAP_3 MTABC_N MLANA
Other DBs
NCBI-GeneID: 103660962
NCBI-ProteinID: XP_040495758
UniProt: A0A8M1GJ99
LinkDB
Position
Unknown
AA seq 1164 aa
MPGALQGHEEYAANCIRLDMQWVEGTVSEGLSGLLETQIRRQAGIAGYRAAEGARPGPAP
DCPGLGARNFSALPGSATQPALCSPVARGAGEQVLAPSSTSSRALAPAPAPXAMGPGPRR
AACVQRPLLCALALMVAAGGRVASAFNLDTRFLVVKEARNPGSLFGYSVALHRQTERQQR
YLLLAGAPRDLAVPDGYTNRTGAVYLCPLTAHKNDCERMDISEKSDPDHHIIEDMWLGVT
VASQGPAGRVLVCAHRYTQVLWSGSEDQRRMVGKCYVRGNDLELDPTDDWQTYHNEMCNS
NTDYLATGMCQLGTSGGFTHNTVYFGAPGAYNWQGNSYMIQRKDWDLSEYSYKDSENQGN
LYIGYTVQVGSAVLHPTNITIVTGAPRHQHMGAVFLLSQEAGGDLRKRQVLEGTQVGAYF
GSAIALADLNNDGWQDLLVGAPYYFERKEEVGGALYVFMNQAGTSFPAHPSLLLHGPSRS
AFGFSVASIGDINQDGFQDVAVGAPFEGSGKVYVYHSSSRGLLGRPQQVIHGEELGLPGL
ATFGYSLSGRMDVDENSYPDLLVGSLSDRIVLLRARPVINILHKTLVARPSVLDPALCTA
TSCVQVEVCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFARSQSAVFHGFFSMPD
MRCQKLELLLMDNVRDKLRPIIISMNYSLPLRMPERPRLGLRSLDPYPVLNQAQVLENHT
EVHFQKECGQDNKCDSNLQMRAAFLSELGQPLSRLQYSRDGRKLLLSIDVTNTPSRERAG
EDAHEALLTLTVPPALLLSSVRPAGMCQANETIVCELGNPFKRNQRMELLIAFEVTGVTL
HTRELQAQLQLSTSSHQDDLWPVTLTLLVDYTLQASLSIVNHRLQSFFGGTVTGESGMKT
VEDVGSPLKYEFQVGPVGEGLAALGTLVLGLEWPYEVINGKWLLYPAEITIHGNGSWPCR
PPGDLVNPLNLTLSVPGDRPPSPQRRRRQLDPGGGPAPPPVTLAAAKKAKSETKLKCGSD
QARCVWLECPIPDTPVITNVTVQARVWNSTFIEDYRDFDRVSVSGWATLFLRTSIPTINM
ENKTVWFSVDIDSDLVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRARTRAL
YEAKRQKAEMKSQPSETERLTDDY
NT seq 3495 nt   +upstreamnt  +downstreamnt
atgccgggtgctctccagggccatgaggagtacgcagccaattgcattcggctggacatg
cagtgggttgaagggactgtgtctgagggactgtcggggctgctggaaacgcagattcgc
cgccaagccgggatcgcaggctaccgtgcggccgagggggcgcggccgggaccagctccg
gactgcccggggctgggggccagaaacttctcagcgctgccgggctcagcgacgcagccc
gccctatgttctccggtggcgcggggagcaggtgaacaggtcctcgctcccagctccacg
tcctcacgcgctctcgccccggcccccgccccgncagccatgggccccggcccccgccgc
gccgcctgcgtccagcgcccgctgctctgcgcgctcgccctgatggtggccgccggcggc
cgcgtcgcctccgccttcaacctggacacccgattcctggtggtgaaggaggccaggaac
ccgggcagcctcttcggctactcggtcgccctccaccggcagacggagcggcagcagcgc
tacctgctcctggctggtgctccccgggacctcgccgtgcctgatggctacaccaaccgg
accggtgctgtgtacctgtgtccactcactgcccacaagaacgactgtgagcggatggac
atctcagagaaaagtgaccctgaccatcacattattgaggatatgtggcttggggtgacg
gtggccagtcagggccctgcaggcagagtcctggtctgcgcccaccgctacacccaggtg
ctatggtcagggtcggaggaccagcggcgcatggtgggcaagtgctacgtgcggggcaat
gacctcgagctggaccccaccgatgactggcagacctaccacaatgagatgtgcaacagc
aacactgactacctggcgacaggcatgtgccagctgggcaccagcggcggcttcacccac
aacaccgtgtacttcggcgctcccggggcctacaactggcaaggaaacagctacatgatt
cagcggaaggactgggatttatccgaatatagttataaggactcagagaaccaaggaaac
ctctatattggatacacagtgcaggtgggcagcgccgtcctgcaccccacgaacatcacc
atcgtgacaggtgccccccggcaccaacatatgggcgctgtcttcttgctgagccaggag
gcaggcggagacctgcggaagaggcaggtgctggagggcacgcaggtgggcgcctatttt
ggcagcgccattgccctggcagacctgaacaatgatgggtggcaggacctcctggtgggt
gccccatactactttgagcggaaggaagaggtagggggtgctctgtatgtcttcatgaac
caggcaggcacctcctttcctgcccacccctccctccttctccacggccccagtcgctcc
gcctttggcttctccgtggccagcattggtgacatcaaccaggatggattccaggacgtt
gccgtgggagccccgttcgagggctcgggcaaagtgtacgtctaccacagcagctcccgg
gggcttctgggacggccgcagcaggtaatccacggggaggagctgggactgcccggcttg
gccaccttcggctactcactgagcgggcggatggacgtggatgagaactcctacccggac
ctgctggtggggagcctgtcagaccgcatcgtgctgctgcgggcacggcctgtcatcaac
atcctccacaagaccttggtggccaggccatccgtgctggaccctgcgctctgcacagcc
acctcctgcgtgcaggtggaggtgtgctttgcttacaaccagagtgcggggaaccccaac
tacaggcgaaacatcaccctggcctacacattggaggccgatcgggaccgccgaccccct
cggcttcgctttgcacgcagccagtcagccgttttccacggcttcttctccatgcctgac
atgcgctgccagaagctggaactgctcctgatggacaacgtccgcgacaaactccgtccc
atcatcatctctatgaactactctttacctttgaggatgcccgagcgcccccggctgggg
ctgcggtccctagacccctacccggtgctgaaccaggcgcaggttctggagaaccacacc
gaggtccacttccagaaagagtgcggccaggacaacaaatgcgacagcaatttgcagatg
cgggcggccttcctgtcggagctggggcagccgctgagcaggctgcagtatagcagagat
ggccggaaactgctcctgagcatcgatgtgaccaacaccccaagcagggagcgcgctggg
gaggacgcccacgaggcgctgctcaccctgaccgtgcctcccgccctgctgctgtcttca
gtgcgccccgctgggatgtgccaggccaatgagaccattgtctgtgagctggggaacccc
ttcaagcggaaccagaggatggagctgctcatcgccttcgaggtcaccggagtgaccttg
cacacacgggaactccaggcgcagctgcagctctccacgtcaagtcaccaggacgacctg
tggcccgtgaccttgactctgctggtggactacacactccaggcctcactcagcatagtg
aatcaccggctacaaagcttcttcggagggacagtgacgggcgagtctggcatgaaaact
gtggaggatgtgggaagccccctcaagtatgagttccaggtgggcccagtgggggaaggg
ctggcagccctggggaccctggtcctagggctggagtggccctatgaagtcatcaatggc
aagtggctgctgtaccccgcggagatcaccatccatggcaatgggtcctggccctgccga
ccacctggagaccttgtcaaccctctgaacctcacactctctgtccctggggacaggcca
ccatctccacagcgcaggcggagacagctggacccagggggaggcccggcccccccgcca
gtcactctggctgctgccaagaaagccaagtctgagacaaagctgaagtgtggcagtgac
caggcccgctgtgtgtggctggaatgccccattcccgatacccctgtcatcaccaatgtg
acagtgcaggcacgagtatggaacagcaccttcattgaggattacagagactttgacaga
gtcagtgtatccggctgggctaccctgttcctccgaaccagcatccccaccatcaacatg
gagaacaagaccgtgtggttctccgtggacattgactctgacctggtggaggagctgcca
gcggagatcgagctgtggctggtgcttgtggctgtgggtgccgggctgctgctgctgggg
ctgatcattctcctgctgtggaagtgcggcttcttcaagcgagcccgcactcgcgccctg
tatgaagctaagaggcagaaggcggagatgaagagccagccgtcagagacagagaggctg
acggacgactactga

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