Ursus maritimus (polar bear): 103661071 Help Entry 103661071         CDS       T03271                                  Symbol ACTN4 Name (RefSeq) alpha-actinin-4   KO K05699   actinin alpha 1/4 Organism umr  Ursus maritimus (polar bear) Pathway umr04510   Focal adhesion umr04517   IgSF CAM signaling umr04518   Integrin signaling umr04519   Cadherin signaling umr04520   Adherens junction umr04530   Tight junction umr04670   Leukocyte transendothelial migration umr04810   Regulation of actin cytoskeleton umr05146   Amoebiasis umr05203   Viral carcinogenesis umr05322   Systemic lupus erythematosus Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04517 IgSF CAM signaling     103661071 (ACTN4)    04518 Integrin signaling     103661071 (ACTN4)    04519 Cadherin signaling     103661071 (ACTN4)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     103661071 (ACTN4)    04520 Adherens junction     103661071 (ACTN4)    04530 Tight junction     103661071 (ACTN4)   09142 Cell motility    04810 Regulation of actin cytoskeleton     103661071 (ACTN4)  09150 Organismal Systems   09151 Immune system    04670 Leukocyte transendothelial migration     103661071 (ACTN4)  09160 Human Diseases   09161 Cancer: overview    05203 Viral carcinogenesis     103661071 (ACTN4)   09174 Infectious disease: parasitic    05146 Amoebiasis     103661071 (ACTN4)   09163 Immune disease    05322 Systemic lupus erythematosus     103661071 (ACTN4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:umr04131]     103661071 (ACTN4)   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:umr04812]     103661071 (ACTN4)    04147 Exosome [BR:umr04147]     103661071 (ACTN4) Membrane trafficking [BR:umr04131]  Exocytosis   Small GTPases and associated proteins    Rab associated proteins     103661071 (ACTN4) Cytoskeleton proteins [BR:umr04812]  Eukaryotic cytoskeleton proteins   Actin filaments / Microfilaments    Actin-binding proteins     Cross-linking proteins      103661071 (ACTN4) Exosome [BR:umr04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    103661071 (ACTN4)   Exosomal proteins of colorectal cancer cells    103661071 (ACTN4)   Exosomal proteins of bladder cancer cells    103661071 (ACTN4) SSDB OrthologParalogGFIT Motif Pfam:  Spectrin CH EFhand_Ca_insen EF-hand_1 EF-hand_6 EF-hand_7 XisI Motif Other DBs NCBI-GeneID:  103661071 NCBI-ProteinID:  XP_040489872 UniProt:  A0A8M1G5J8 LinkDB All DBs Position Unknown AA seq 911 aa AA seqDB search MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKTFTAWC NSHLRKAGTQIENIDEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIA SKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPY KNVNVQNFHISWKDGLAFNALIHRHRPELIEYDKLRKDDPVTNLNNAFEVAEKYLDIPKM LDAEDIVNTARPDEKAIMTYVSSFYHAFSGAQKAETAANRICKVLAVNQENEHLMEDYER LASDLLEWIRRTIPWLEDRVPQKTIQEMQQKLEDFRDYRRVHKPPKVQEKCQLEINFNTL QTKLRLSNRPAFMPSEGRMVSDINNGWQHLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQ KASIHEAWTDGKEAMLKHRDYETATLSDIKALIRKHEAFESDLAAHQDRVEQIAAIAQEL NELDYYDSHNVNTRCQKICDQWDALGSLTQSRREALEKTEKQLETIDQLHLEYAKRAAPF NNWMESAMEDLQDMFIVHTIEEIEGLISAHDQFKSTLPDADREREAILAIHKEAQRIAES NHIKLSGSNPYTTVTPQIINSKWEKVQQLVPKRDHALLEEQSKQQSNEHLRRQFASQANI VGPWIQTKMEEIGRISIEMNGTLEDQLNHLKRYERSIVDYKPNLDLLEQQHQLIQEALIF DNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMQEFRASFNHFDKD HGGALGPEEFKACLISLGYDVENDRQGDAEFNRIMSVVDPNHSGLVTFQAFIDFMSRETT DTDTADQVIASFKVLAGDKNFITAEELRRELPPDQAEYCIARMAPYQGPDAVPGALDYKS FSTALYGESDL NT seq 2736 nt NT seq  +upstreamnt  +downstreamnt atggtggactaccacgcggcgaaccagtcgtaccagtacggccccagcagcgcgggcaat ggcgccggcggcgggggaagcatgggcgactacatggcccaggaggacgactgggaccgg gacctgctgctggacccggcctgggagaagcagcagcgcaagacattcacagcctggtgc aactcccacctgcggaaggctggcacgcagatagagaacatcgacgaggacttccgagac gggctcaagctcatgctccttctagaggtcatttcaggagagcggttacctaagccagag cggggcaagatgagagtgcacaagatcaacaatgtgaacaaagctctggacttcatcgcc agcaaaggagtcaagctcgtctccatcggggcagaagagattgtggacggtaatgcaaag atgaccctgggaatgatctggaccatcatcctcaggttcgccatccaggacatctccgtg gaagagacctctgccaaggagggactgcttctgtggtgccagaggaagacggccccgtat aagaacgtcaacgtgcagaacttccacatcagctggaaggacggtcttgccttcaatgca ctgatccaccggcacagaccagagctgatcgagtatgacaagctgagaaaggatgacccc gttaccaacctgaacaatgctttcgaagtggccgagaaatacctagacatccccaagatg ttggatgctgaggacatcgtgaacacggcccggcccgacgagaaggccataatgacctat gtgtccagcttctaccatgccttttcgggagcgcagaaggctgagactgcggccaaccgg atctgcaaggtgctggccgtcaaccaagagaatgagcacctcatggaagattatgagagg ctggccagtgatctcctggagtggatccggcgtaccatcccctggctggaggaccgggtg ccgcagaagaccatccaggagatgcagcagaagctggaggacttccgggactaccggcgt gtgcacaagccgcccaaggtgcaggagaagtgccagctggagatcaacttcaacacgctg cagaccaaactgcgcctcagcaaccggcccgccttcatgccctccgagggcaggatggtc tcggacatcaacaacggctggcagcacctggagcaggccgagaagggctacgaggagtgg ctgctgaatgagatccgcaggctggagcggcttgaccacctggcagagaagttccggcag aaggcctccatccacgaggcctggaccgacgggaaggaagccatgctgaagcaccgggac tacgagacagccaccctgtcggatatcaaagccctcattcgcaagcacgaggcctttgag agcgacctggccgcacaccaggaccgagtggagcagattgcggccattgctcaggagctc aacgagctggactactacgactcccacaacgtcaacacccgctgccagaagatctgcgac cagtgggatgccctcggctctctgacccagagtcgcagggaagctctggagaaaacggag aagcagctggagaccattgaccagctgcacctggagtacgccaagcgggcggcgcccttc aacaactggatggagagcgccatggaggacctgcaggacatgttcatcgtccacaccatt gaggagatcgagggcctgatttcagctcacgaccagttcaagtcgacgctgccggacgcc gacagggagcgggaggccatcctggccatccacaaggaggcgcagaggatcgctgagagc aaccacatcaagctgtcgggcagcaacccctacaccaccgtcaccccacagatcatcaac tccaagtgggagaaggtgcagcagctggtgcccaagcgggaccacgccctcctggaggag cagagcaagcagcagtccaacgagcacctccgccgccagtttgccagccaggccaacatt gtggggccctggatccagacgaagatggaggagatcgggcgcatctccatcgagatgaac gggaccctggaggaccagctgaaccacttgaagcggtacgagcgcagcatcgtggactac aagccgaacctcgacctgctcgagcagcagcaccagctcatccaggaggccctcatcttc gacaacaagcacaccaactacaccatggagcacatccgcgtgggctgggagcagctgctc accaccatcgcccgcaccatcaacgaggtcgagaaccagatcctcacccgtgatgccaag ggcatcagccaggagcagatgcaggagttccgggcgtccttcaaccacttcgacaaggac cacggcggggcgctggggccggaggagttcaaggcctgtctcatcagcctgggctacgac gtggagaatgaccggcagggtgatgccgagttcaaccgcatcatgagcgtggttgacccc aaccacagtgggctcgtgaccttccaagccttcattgacttcatgtcaagggagaccacc gacacagatacggccgaccaggtcatcgcctccttcaaggtcctggcaggggacaagaac ttcatcacagctgaggagctgcggagagagctgcccccggaccaggctgagtactgcatc gcacgcatggcgccctatcagggccccgacgctgtgcccggcgccctcgactacaagtcc ttctcgacagccctgtacggcgagagtgacctgtga

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