Ursus maritimus (polar bear): 103661275
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Entry
103661275 CDS
T03271
Symbol
ATP2A2
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 2
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr04020
Calcium signaling pathway
umr04022
cGMP-PKG signaling pathway
umr04024
cAMP signaling pathway
umr04148
Efferocytosis
umr04260
Cardiac muscle contraction
umr04261
Adrenergic signaling in cardiomyocytes
umr04380
Osteoclast differentiation
umr04919
Thyroid hormone signaling pathway
umr04972
Pancreatic secretion
umr05010
Alzheimer disease
umr05017
Spinocerebellar ataxia
umr05022
Pathways of neurodegeneration - multiple diseases
umr05410
Hypertrophic cardiomyopathy
umr05412
Arrhythmogenic right ventricular cardiomyopathy
umr05414
Dilated cardiomyopathy
umr05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
103661275 (ATP2A2)
04024 cAMP signaling pathway
103661275 (ATP2A2)
04022 cGMP-PKG signaling pathway
103661275 (ATP2A2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
103661275 (ATP2A2)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
103661275 (ATP2A2)
09153 Circulatory system
04260 Cardiac muscle contraction
103661275 (ATP2A2)
04261 Adrenergic signaling in cardiomyocytes
103661275 (ATP2A2)
09154 Digestive system
04972 Pancreatic secretion
103661275 (ATP2A2)
09158 Development and regeneration
04380 Osteoclast differentiation
103661275 (ATP2A2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
103661275 (ATP2A2)
05017 Spinocerebellar ataxia
103661275 (ATP2A2)
05022 Pathways of neurodegeneration - multiple diseases
103661275 (ATP2A2)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
103661275 (ATP2A2)
05412 Arrhythmogenic right ventricular cardiomyopathy
103661275 (ATP2A2)
05414 Dilated cardiomyopathy
103661275 (ATP2A2)
05415 Diabetic cardiomyopathy
103661275 (ATP2A2)
Enzymes [BR:
umr01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
103661275 (ATP2A2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Cation_ATPase
Cation_ATPase_C
E1-E2_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
Motif
Other DBs
NCBI-GeneID:
103661275
NCBI-ProteinID:
XP_040475878
UniProt:
A0A8M1EXW5
LinkDB
All DBs
Position
Unknown
AA seq
1042 aa
AA seq
DB search
MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK
EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV
ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFILDRVEGDSCSLHEFTITGSTYAPIGEVHKDDKPVKCHQYDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK
KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTPGV
KQKVMSVIREWGSGSDTLRCLALATHDNPLRREEMNLEDSANFIKYETNLTFVGCVGMLD
PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL
NPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKSEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG
CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKDDNPDFEGVDCAIFESPYPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP
LNLTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSFSACTDGISWPFVL
LIMPLVIWVYSTDTNFSDMFWS
NT seq
3129 nt
NT seq
+upstream
nt +downstream
nt
atggagaacgcgcacacaaagacggtggaggaggtgctgggccacttcggcgtcaacgag
agcacggggctgagcctggagcaggtcaagaagctcaaggagagatggggctctaacgag
ctaccggctgaagaaggaaaaaccttgctggaacttgtgatcgagcagtttgaagactta
ctagttagaattttattgctggcagcttgtatatcttttgttttggcttggtttgaagaa
ggtgaagaaacaattacagcctttgtagaaccctttgtaattttacttatattagtagcc
aatgcaattgtgggtgtatggcaggaaagaaatgctgagaatgcaatcgaagcccttaag
gaatatgagcctgaaatgggcaaagtatatcgacaggacagaaagagtgtccagcggatt
aaagctaaagacatagttcctggtgatattgtagaaattgctgttggtgacaaagttcct
gcagatataagattaacttccatcaaatctactactctaagggttgaccagtccattctc
acaggtgagtctgtgtctgtcatcaagcacactgaccctgtcccggacccacgggctgtc
aatcaagataaaaagaacatgctcttttctggtacaaacattgctgctggcaaagccatg
ggagtggtggtggcaactggagtgaacacagaaattggcaagatccgggatgaaatggtg
gcaacagagcaggagagaacccccctccagcagaaactagacgagtttggtgaacagctt
tcgaaagtcatctccctgatttgcattgcagtctggatcataaacattgggcacttcaat
gacccagttcatggaggctcctggatcaggggcgctatttactacttcaaaattgcagtg
gctctggctgtggcagccattcctgaaggtctgcctgctgtcatcaccacctgcctggct
cttggaactcgcagaatggcaaagaaaaatgctattgttcgaagcctcccttctgtggaa
acccttggttgtacttctgttatctgctcagacaagactggtacactgacaacaaaccag
atgtctgtgtgcaggatgttcattctggacagagttgaaggtgatagttgttcccttcat
gagtttaccattactggatcaacatacgcacctattggagaagtgcataaagatgataaa
ccagtgaaatgtcatcaatatgatggtcttgtggaattggcaacaatttgtgctctttgt
aatgattccgcattggattacaatgaggcaaagggtgtatatgaaaaagttggagaagct
acagagactgctctcacttgcctagtagagaagatgaatgtatttgataccgaattgaag
ggtctttctaaaatagagcgagcaaatgcctgcaactcggtcattaagcagttgatgaaa
aaggaattcactctggagttttcacgtgatagaaaatcgatgtcagtttattgtacacca
aacaaacctagccggacatcaatgagcaaaatgtttgtgaagggtgctcctgaaggtgtc
attgacaggtgcacccacattcgagttggaagtactaaagtgcctatgaccccgggagtc
aaacagaaggtcatgtctgtcattcgggaatggggtagcggcagcgacacactgcggtgc
ctggctctggccactcacgacaacccactgagaagagaagaaatgaaccttgaggactct
gccaactttattaaatatgagaccaatctgacttttgttggctgcgtgggcatgctggac
cctccaagaattgaagtggcctcttctgtgaagctgtgccggcaagcaggcatccgggtc
atcatgatcacaggggacaacaagggcactgctgtggccatctgtcggcgcattggaatc
ttcgggcaggacgaggatgtgacatcaaaggcttttacgggtcgggagtttgatgagctc
aatccttcagcccagagagatgcctgtttgaatgcccgctgttttgctcgagttgaacct
tcccacaagtcaaaaattgtagaatttcttcagtcttttgatgagattacagctatgact
ggggatggcgtgaatgacgctcctgccctgaagaaatcggagatcggcatcgccatgggc
tccggcacggcagtggctaaaaccgcctctgagatggtcctggccgatgacaacttctcc
accatcgtggccgctgtcgaggaggggcgggcaatctacaacaatatgaagcagttcatc
cgctacctcatctcatcaaatgtgggggaagttgtctgtatcttcctgacggcagctctt
ggatttcctgaggctttaattcctgtccagctcctctgggtcaatctggtgacagacggc
ctgcctgccaccgccctggggtttaaccctcctgatctggacatcatgaataaaccaccc
cggaacccgaaggaacccctgatcagcggatggctctttttccgttacctggccattggc
tgttacgttggcgctgctacggtgggtgctgctgcctggtggttcattgctgccgatgga
ggtccaagagtgtccttctaccagctgagccacttcctacagtgtaaagatgacaacccg
gattttgaaggagtggattgtgcaatcttcgagtccccgtacccgatgacaatggcgctg
tctgttcttgtaaccatagagatgtgtaacgccctcaacagcttgtctgaaaaccagtcc
ctgctgaggatgcccccctgggagaacatctggctcgtgggctccatctgcctgtccatg
tcgctccacttcctcatcctctacgtggaaccgttgccacttattttccagatcacaccg
ctgaatttgacccagtggctgatggtgctgaaaatctccttgcctgtgattctaatggac
gagacactcaagtttgtggcccgcaactacctggaacctggtaaagagtgtgtgcagcct
gccaccaaatcctgctcgttctcggcatgcaccgatgggatttcctggccgtttgtgctg
ctcataatgcccctggtgatctgggtctatagcacagacactaactttagtgatatgttt
tggtcttga
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