Ursus maritimus (polar bear): 103661560
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Entry
103661560 CDS
T03271
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr01521
EGFR tyrosine kinase inhibitor resistance
umr01522
Endocrine resistance
umr01524
Platinum drug resistance
umr04010
MAPK signaling pathway
umr04012
ErbB signaling pathway
umr04020
Calcium signaling pathway
umr04066
HIF-1 signaling pathway
umr04151
PI3K-Akt signaling pathway
umr04510
Focal adhesion
umr04520
Adherens junction
umr04530
Tight junction
umr05200
Pathways in cancer
umr05205
Proteoglycans in cancer
umr05206
MicroRNAs in cancer
umr05212
Pancreatic cancer
umr05213
Endometrial cancer
umr05215
Prostate cancer
umr05219
Bladder cancer
umr05223
Non-small cell lung cancer
umr05224
Breast cancer
umr05226
Gastric cancer
umr05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103661560 (ERBB2)
04012 ErbB signaling pathway
103661560 (ERBB2)
04066 HIF-1 signaling pathway
103661560 (ERBB2)
04020 Calcium signaling pathway
103661560 (ERBB2)
04151 PI3K-Akt signaling pathway
103661560 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
103661560 (ERBB2)
04520 Adherens junction
103661560 (ERBB2)
04530 Tight junction
103661560 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103661560 (ERBB2)
05206 MicroRNAs in cancer
103661560 (ERBB2)
05205 Proteoglycans in cancer
103661560 (ERBB2)
05230 Central carbon metabolism in cancer
103661560 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
103661560 (ERBB2)
05226 Gastric cancer
103661560 (ERBB2)
05219 Bladder cancer
103661560 (ERBB2)
05215 Prostate cancer
103661560 (ERBB2)
05213 Endometrial cancer
103661560 (ERBB2)
05224 Breast cancer
103661560 (ERBB2)
05223 Non-small cell lung cancer
103661560 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
103661560 (ERBB2)
01524 Platinum drug resistance
103661560 (ERBB2)
01522 Endocrine resistance
103661560 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
umr01001
]
103661560 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
umr04147
]
103661560 (ERBB2)
04090 CD molecules [BR:
umr04090
]
103661560 (ERBB2)
Enzymes [BR:
umr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
103661560 (ERBB2)
Protein kinases [BR:
umr01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
103661560 (ERBB2)
Exosome [BR:
umr04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
103661560 (ERBB2)
CD molecules [BR:
umr04090
]
Proteins
103661560 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Haspin_kinase
Kinase-like
Motif
Other DBs
NCBI-GeneID:
103661560
NCBI-ProteinID:
XP_040496620
UniProt:
A0A8M1GNK5
LinkDB
All DBs
Position
Unknown
AA seq
1260 aa
AA seq
DB search
MELAAWCRWGLLLALLPSGAAGTQVCTGTDMKLRLPASPETHLDMLRHLYQACQVVQGNL
ELTYLPANASLSFLQDIQEVQGYVLIAHSQVRQVPLQRLRIVRGTQLFEDNYALAVLDNG
EPPEGDTSVAGATPGGLRELQLRSLTEILKGGVLIQRNPRLCHQDTILWKDIFHKNNQLA
LTLIDTNRSRACQPCSPACKDPHCWGASSGDCQSLTRTVCAGGCARCKGPKPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSRPCARVCYGLGMEHLREARAVTSAN
IQEFAGCKKIFGSLAFLPESFEGDPASNTAPLQPEQLRVFEALEEITGYLYISAWPDSLP
NLSVFQNLRVIRGRVLHDGAYSLTLQGLGISWLGLRSLRELGSGLALIHRNARLCFIHTV
PWEQLFRNPHQALLHSANRPEAECVGEGLACYPLCAHGHCWGPGPTQCVNCSQFLRGQEC
VEECRELHGLPREYVKDRYCLPCHPECRPQNGSVTCFGSEADQCVACAHYKDPPSCVARC
PSGVKPDLSFMPIWKFADEEGTCQPCPINCTHSCGDLDERGCPAEQRASPVTSIIAAVVG
ILLAVVMGLVLGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPEPAPGAGGPAHCRHRSSSTRSGGGELTVGLEPSEEEPPKSPLAPSEG
AGSDMFDGDLGMGAAKGLQSLPPQDPSPLQRYSEDPTVPLPPETDGYVAPLTSSPQPEYV
NQPEVWPQPPSPLEGPLPPPRPAGATLERPKTLSPKTLSPGKNGVIKDVFAFGSAVENPE
YLAPRGRAAPQLHPPPAFSPAFDNLYYWDQDPSERGSPPSTFEGTPTAENPEYLGLDVPV
NT seq
3783 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgctgggggctcctcctcgccctcctgccctccggagcc
gcgggcacccaagtgtgcaccggcacagacatgaagctgcggctccctgccagtcccgag
acccacctggatatgctccgccacctctaccaggcctgtcaagtggtacagggtaacctg
gagctcacctacctgcccgccaatgccagcctgtccttcctgcaggatatccaggaggta
cagggctatgtgctcattgctcacagccaagtgagacaggtcccgctgcagaggctccga
atcgtgcgaggcacccagctctttgaggacaactacgccctggccgtgctggacaatgga
gagccgcccgagggggacacctctgtggcaggggctaccccaggagggctgcgggagctg
cagcttcgaagcctcacagagatcctgaagggaggggtcttgattcagcggaacccacgg
ctctgccaccaggacacgattttgtggaaggacatcttccacaagaacaaccagctggcc
ctcacgctgatagacaccaaccgctctcgggcctgccaaccctgttctccagcctgtaaa
gacccccactgctggggagcaagttccggggactgtcagagcttgacacgaaccgtctgt
gccggcggctgtgcccgctgcaagggcccaaaacccactgactgctgccacgagcagtgc
gcggctggctgcacgggccccaagcactcggactgcctggcctgccttcacttcaaccac
agtggcatctgtgagctgcactgcccagccctggtcacctacaacacggacacgttcgaa
tccatgcccaaccctgagggccgatacaccttcggtgccagctgtgtgaccgcctgtccc
tacaactacctgtccacggacgtgggatcctgcaccctggtctgtcccctgaacaaccaa
gaggtgacggctgaggatggcacccagcggtgtgagaaatgcagcagaccctgtgcccga
gtgtgctatggtctgggcatggagcacctgcgggaggcgagggcggtcaccagcgccaac
atccaagaattcgccggctgcaagaagatctttgggagcctggcgtttctgccagagagc
ttcgagggagacccagcctccaacactgcccccctgcagcctgaacagctcagagtgttc
gaggccctggaggagatcacaggttacctgtatatctcagcgtggccggacagcttgcct
aacctcagtgtcttccagaacctgcgagtaatccggggacgagttctgcatgatggcgcc
tactcgctgaccctgcaagggctgggcatcagctggctggggctgcgctcgctgcgggaa
ctgggcagcgggctggccctcatccaccgcaacgcccgcctctgcttcatccacacggtg
ccctgggagcagctcttccggaacccccaccaagccctgctgcacagtgccaaccggccg
gaggccgagtgcgtgggcgagggcctggcctgctacccgctgtgcgcccatgggcactgc
tggggtccggggcccacccagtgcgtcaactgcagccaattccttcggggccaggagtgc
gtggaggaatgccgagaactgcacgggctaccccgggaatatgtgaaggacagatactgt
ctgccatgccaccccgagtgtcggccccagaatggctcagtgacctgctttgggtcggag
gctgaccagtgtgtggcctgcgcccactacaaggaccctccctcctgcgtggctcgctgc
cccagtggtgtgaaacccgacctctctttcatgcccatttggaagtttgcagatgaggag
ggcacatgccagccgtgccccatcaactgcacccactcctgtggggacctggacgagagg
ggctgccccgccgaacagagagccagccctgtgacatccatcattgccgctgtggtgggc
attctgctggccgtggtcatggggctggtcctcggcatcctgatcaagcgaaggcgacag
aagatccgcaagtacacgatgcggaggttgctgcaggaaaccgagctggtggagccgctg
acgcctagcggagcgatgcccaaccaggctcagatgcggatcctgaaagagacagagctg
aggaaggtgaaggtgcttggatccggagcttttggcacggtctacaagggcatctggatc
cctgacggggaaaatgtgaaaatcccagtggccatcaaagtgttgagggaaaacacatct
cccaaagccaacaaagaaatcttggacgaagcatatgtgatggctggagtgggctcccca
tatgtgtcccgccttctgggcatctgcctgacgtccacggtgcagctggtgacacagctt
atgccctatggctgcctcttagaccacgtccgagagcaccgtgggcgtctgggctcccag
gacctcctgaactggtgtgtgcagatcgccaaggggatgagctacttggaggacgtccgg
ctcgtgcacagggacctggctgcccggaacgtgctggtcaagagtcccaaccatgtcaag
attacagacttcgggctggctcggttgctggacattgatgagaccgagtaccacgcggat
gggggcaaggtgcccatcaagtggatggcgctggagtccattctccgccggcggttcacc
caccagagtgacgtgtggagctacggtgtgactgtgtgggaactgatgacttttggggcc
aaaccttacgatgggatcccagcccgagagatccctgacctgctggagaagggggaacgg
ctgccccagccccccatctgcaccatcgacgtctacatgattatggttaaatgttggatg
atagactctgaatgtcgaccacggttccgggagttggtggccgaattctcccgtatggcc
agggacccccagcgctttgtggtcatccagaatgaagacctgggccccgccagcccattg
gacagcaccttctaccgttcgctgctggaagatgatgacatgggggacctggtggatgcc
gaggagtacctggtgccccagcaggggttcttctgcccagaacctgcccctggagcgggg
ggcccggcccactgcaggcaccgcagctcgtccaccaggagtggcggtggtgagctgaca
gtgggactggagccctctgaggaggagccccccaagtctccactggccccgtcagagggg
gctggctctgacatgtttgatggtgacttgggaatgggggcagccaaggggctgcagagc
cttcccccccaggacccgagccctctacagcggtacagcgaggaccctacagtacccctg
ccccctgagactgatggctacgttgcccccctgaccagcagccctcagcctgaatacgtg
aaccagccagaggtttggccgcagcccccctcacccctagaaggccctctgcctcctcct
cgacctgctggtgccaccctggaaaggcccaagactctgtcccccaagaccctctcccct
ggcaagaatggggtcatcaaagacgtttttgcctttgggagtgcggtggagaaccctgag
tacttggcaccccggggcagggctgcccctcagctccaccctcctccagccttcagccca
gcctttgacaacctctattactgggaccaggacccatcagagcggggctctccacccagt
acctttgaagggacccctacagcagagaaccctgagtacctgggcctggacgtgccagtg
tga
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integrated database retrieval system
