Ursus maritimus (polar bear): 103662312
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Entry
103662312 CDS
T03271
Symbol
CBL
Name
(RefSeq) E3 ubiquitin-protein ligase CBL isoform X1
KO
K04707
E3 ubiquitin-protein ligase CBL [EC:
2.3.2.27
]
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr04012
ErbB signaling pathway
umr04120
Ubiquitin mediated proteolysis
umr04144
Endocytosis
umr04910
Insulin signaling pathway
umr05100
Bacterial invasion of epithelial cells
umr05200
Pathways in cancer
umr05205
Proteoglycans in cancer
umr05220
Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
103662312 (CBL)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
103662312 (CBL)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
103662312 (CBL)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
103662312 (CBL)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103662312 (CBL)
05205 Proteoglycans in cancer
103662312 (CBL)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
103662312 (CBL)
09171 Infectious disease: bacterial
05100 Bacterial invasion of epithelial cells
103662312 (CBL)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
umr04131
]
103662312 (CBL)
04121 Ubiquitin system [BR:
umr04121
]
103662312 (CBL)
Enzymes [BR:
umr01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
103662312 (CBL)
Membrane trafficking [BR:
umr04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
103662312 (CBL)
Ubiquitin system [BR:
umr04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
CBL proteins
103662312 (CBL)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Cbl_N
Cbl_N3
Cbl_N2
zf-C3HC4
zf-C3HC4_3
Prok-RING_4
zf-RING_2
UBA
RING_XB3-XBAT31
zf-C3HC4_2
zf-RING_UBOX
zf-RING_5
zf-rbx1
zf-C3HC4_4
UBA_RAD5A
Motif
Other DBs
NCBI-GeneID:
103662312
NCBI-ProteinID:
XP_040487063
UniProt:
A0A8M1FUM8
LinkDB
All DBs
Position
Unknown
AA seq
910 aa
AA seq
DB search
MAGNVKKSSGAGGGGGSGGSGSGGLIGLMKDAFQPHHHHHHLSPHPPGTVDKKMVEKCWK
LMDKVVRLCQNPKLALKNSPPYILDLLPDTYQHLRTILSRYEGKMETLGENEYFRVFMEN
LMKKTKQTISLFKEGKERMYEENSQPRRNLTKLSLIFSHMLAELKGIFPSGLFQGDTFRI
TKADAAEFWRKAFGEKTIVPWKSFRQALHEVHPISSGLEAMALKSTIDLTCNDYISVFEF
DIFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTRLG
QWAIGYVTADGNILQTIPHNKPLFQALIDGFREGFYLFPDGRNQNPDLTGLCEPTPQDHI
KVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQESEGQGCPFCRC
EIKGTEPIVVDPFDPRGSGSLLRQGAEGAPSPNYEDDDDERADDSLFMMKELAGAKVERP
PSPFSMAPQASLPPVPPRLDLLQQRVSLPSSASGLGTASKVASGSLHKDKPLPIPPTLRD
LPPPPPPDRPYSVGAETRPQRRPLPCTPGDCPSRDKLPPVPSGRLGESWLPRPIPKVPVV
APNAGDPWTGRELTNRHSLPFSLPSQMEPRTDVSRLGGTFNVDTSMNVTNSPLAGSECEH
PKIKPSASASAIYSLAARPLPVPKLPPGEQCDSEEDTEYMTPSSRPLGLPKPDGKRPLET
TQSSRACECDQQTESCTYEAMYNIQSQATPPAPESSSFGEGHVAAGRAGAGPEGSENEED
GYDVPKPPVPAVLARRTLSDISNASSSFGWLSLEGDPPTHFAEGSQVPERPPKPFPRRIN
SERKAGSCQQGGAAAASSPQLSSEIENLMSQGYSYQDIQKALVIAHNNIEMAKNILREFV
SISSPAHVAT
NT seq
2733 nt
NT seq
+upstream
nt +downstream
nt
atggccggcaacgtgaaaaagagctccggggccgggggcggcggcggctccgggggctcg
ggctcgggcggcctgatcgggctcatgaaggacgccttccagccgcaccaccaccaccac
cacctcagcccccatccgcccggcaccgtggacaagaagatggtggagaagtgctggaag
ctcatggacaaggtggtgcggttgtgtcagaacccaaagctggcgctaaagaatagccca
ccttatatcttagacctgctgccagatacctaccagcatctccgcactatcttgtcaaga
tatgaggggaagatggagacgcttggagaaaatgagtattttagggtgttcatggagaac
ttgatgaagaaaactaagcaaaccataagcctcttcaaggaggggaaagaaaggatgtat
gaggagaattctcagcctaggagaaacctaaccaaactatccctgatcttcagccacatg
ctggcagaactaaaaggaatctttccaagtggactctttcaaggagacacgtttcggatt
acgaaggcagatgctgcagagttttggaggaaagcttttggggaaaagacaatagtccct
tggaagagtttccggcaggcccttcatgaggtgcatcccatcagttctgggctcgaggcc
atggctctgaaatccactattgatctgacctgcaatgattatatttcagtttttgaattt
gacatcttcacacgactctttcagccctggtcctctttgctcaggaattggaacagtctt
gccgtgacgcaccctggctacatggctttcctgacgtatgacgaagtgaaagctcggctc
cagaagttcattcacaaacctggcagttacattttccggctgagctgcactcgtctgggt
cagtgggctattggatatgtcactgctgatgggaacattctccagacgatccctcacaat
aaacctctcttccaagccctgatcgatggcttcagggaaggcttctatctgtttccagat
ggacggaatcagaatcccgacctgacgggcttatgtgaacccactccccaggaccacatc
aaagtgacccaggaacaatatgaattatactgtgagatgggctccaccttccagctgtgt
aaaatctgcgctgaaaacgacaaggatgtgaaaattgagccctgtggacacctcatgtgc
acgtcctgtctcacatcctggcaggaatcagaaggccagggctgtcctttctgccgatgt
gaaattaaaggtactgagcccattgtggtagatccgtttgaccctcgaggaagtggcagc
ctcctgaggcaaggagccgagggagctccctccccaaattatgaggacgatgacgatgaa
cgagctgatgattctctctttatgatgaaggaactggctggtgccaaggtggaacggcct
ccttctccgttttcgatggccccacaagcttcccttcccccagtgccaccgcgacttgac
cttctgcaacagcgggtgtcccttccttcaagtgcttctggtcttggaactgcttctaag
gtagcttctggctcccttcataaggacaaaccattaccaatacctcccacacttcgagat
cttccaccaccaccccctccggaccggccatattctgttggagcagaaacccggcctcag
agacgtcccttgccttgtacaccgggtgactgtccatccagggacaaactgccccctgtt
ccctctggccgccttggggaatcgtggctgcctcggccaatccccaaagtaccagtggtt
gccccaaacgctggtgacccctggacaggtagagaattaaccaacaggcactcacttcca
ttttcattgccctcacaaatggagcccagaacagatgtgtccaggcttggaggcacattc
aatgtggatacctccatgaatgtgactaacagcccattagcaggttcagagtgtgagcac
cccaaaatcaagccttctgcatctgccagtgccatttactctctggctgccaggcctctt
cctgtgccaaagctgccccctggggagcagtgtgacagtgaggaggacaccgagtatatg
accccctcctccagacctctagggcttccaaagccagatgggaaacggcctctggagaca
acccagagttcacgagcgtgtgagtgtgaccagcagaccgagagctgtacatatgaagca
atgtataatattcagtcccaggcgacgccgcctgccccggagagcagctccttcggcgaa
gggcatgtggctgcgggccgtgcaggcgccggccccgagggatcagaaaatgaggaagac
ggctatgacgtccctaagccgccagtgccggccgtgctggcccgccggaccctctcagac
atctctaacgccagctcctccttcggctggttgtctctggaaggcgatccccccacacac
ttcgctgagggttcccaggttcctgagaggcctcccaaaccgttccctcggagaatcaac
tcggagcggaaagcaggcagctgtcagcagggtggcgccgcggccgcctcctcgccgcag
ctctccagtgagatcgagaacctcatgagccaggggtactcctaccaggacattcagaaa
gccctggtcattgcccacaacaacatcgaaatggccaagaacatcctccgggaatttgtt
tctatctcgtctcccgcccacgtcgccacctag
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