Ursus maritimus (polar bear): 103663192
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Entry
103663192 CDS
T03271
Symbol
SYK
Name
(RefSeq) tyrosine-protein kinase SYK isoform X1
KO
K05855
spleen tyrosine kinase [EC:
2.7.10.2
]
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr04064
NF-kappa B signaling pathway
umr04072
Phospholipase D signaling pathway
umr04151
PI3K-Akt signaling pathway
umr04380
Osteoclast differentiation
umr04611
Platelet activation
umr04613
Neutrophil extracellular trap formation
umr04625
C-type lectin receptor signaling pathway
umr04650
Natural killer cell mediated cytotoxicity
umr04662
B cell receptor signaling pathway
umr04664
Fc epsilon RI signaling pathway
umr04666
Fc gamma R-mediated phagocytosis
umr05152
Tuberculosis
umr05167
Kaposi sarcoma-associated herpesvirus infection
umr05168
Herpes simplex virus 1 infection
umr05169
Epstein-Barr virus infection
umr05171
Coronavirus disease - COVID-19
umr05203
Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
103663192 (SYK)
04072 Phospholipase D signaling pathway
103663192 (SYK)
04151 PI3K-Akt signaling pathway
103663192 (SYK)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
103663192 (SYK)
04613 Neutrophil extracellular trap formation
103663192 (SYK)
04625 C-type lectin receptor signaling pathway
103663192 (SYK)
04650 Natural killer cell mediated cytotoxicity
103663192 (SYK)
04662 B cell receptor signaling pathway
103663192 (SYK)
04664 Fc epsilon RI signaling pathway
103663192 (SYK)
04666 Fc gamma R-mediated phagocytosis
103663192 (SYK)
09158 Development and regeneration
04380 Osteoclast differentiation
103663192 (SYK)
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
103663192 (SYK)
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
103663192 (SYK)
05168 Herpes simplex virus 1 infection
103663192 (SYK)
05167 Kaposi sarcoma-associated herpesvirus infection
103663192 (SYK)
05169 Epstein-Barr virus infection
103663192 (SYK)
09171 Infectious disease: bacterial
05152 Tuberculosis
103663192 (SYK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
umr01001
]
103663192 (SYK)
Enzymes [BR:
umr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
103663192 (SYK)
Protein kinases [BR:
umr01001
]
Non-receptor tyrosine kinases
SYK family
103663192 (SYK)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
Kdo
DUF7063
ABC1
SH2_1
RIO1
Motif
Other DBs
NCBI-GeneID:
103663192
NCBI-ProteinID:
XP_040476268
UniProt:
A0A8M1EYT3
LinkDB
All DBs
Position
Unknown
AA seq
635 aa
AA seq
DB search
MAGNTADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKA
HHYTIEREMNGTYAIAGGRTHSSPAELCLYHSQESDGLVCVLKKPLHRPPGVQPKTGPFE
DLKESLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISRVESEQI
VMIGSKTNGKFLIRDRNDNGSYALCLLHEGKVLHYRIDKDKTGKLSIPDGKKFDTLWQLV
EHYSYKPDGLLRVLTVPCQKIGGQTGNINFGARAPLPGAHPATWSAGAIISRIKSYSFPK
PGHRKASSSTGNRPESSVTFNPYEPDRGPWATDRDAQREAMPMDTEVYESPYADPEEIRP
KEVYLDRKLLTLEDSELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAE
ANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSM
GMKYLEECNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADESYYKAQTHGKWPVKWYA
PECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVSAMLEKGERMGCPAGCPRE
MYELMKLCWTYEVEKRPGFENVELRLRNYYYDVVN
NT seq
1908 nt
NT seq
+upstream
nt +downstream
nt
atggcgggaaacacggccgacagcgccaaccacctgccattcttcttcggcaacatcacg
cgggaggaggcggaggactacctggtgcaggggggcatgagcgacgggctgtacctgctg
cgtcagagccgcaattacctgggcggcttcgcgctgtcggtggcgcacgggaggaaggcg
caccactacaccatcgagcgcgagatgaacggcacctacgccatcgcgggcggcaggacg
cacagcagcccggccgagctgtgcctctaccactcccaggagtccgacggcctcgtctgc
gtcctcaagaagcccctccaccggccgcccggggtgcagcccaagaccggcccgttcgag
gacctgaaggagagcctcatcagggagtacgtgaagcagacctggaacctgcagggtcag
gctctggagcaggccatcatcagccagaagcctcagctggagaagctgatcgccaccacg
gcccacgagaaaatgccctggttccacgggaaaatctcacgggttgaatctgagcaaatt
gtcatgataggatccaagacaaacggaaaatttttgatcagggacaggaacgacaacggg
tcttacgccctgtgcctgctgcacgaggggaaggtgctgcactatcgcatcgacaaggac
aaaaccgggaagctctccatccccgacgggaagaagttcgacacgctctggcagctcgtg
gagcattactcttacaaaccggacgggctgttgagagttcttacggttccgtgccagaaa
attggcgggcagacaggaaacatcaactttggagcccgcgcgcccctgccaggtgcccac
cctgcgacgtggtcagcgggcgcgataatctccagaatcaaatcctactccttcccaaag
cccggccacagaaaggcctcctcgtccacagggaaccggcccgagagctccgtgaccttc
aatccttatgagccagaccgggggccctgggccacggacagagacgcgcagagagaagcc
atgcccatggacaccgaggtgtacgaaagcccctacgccgaccccgaggagatcaggccc
aaggaggtctacctggaccgcaagctgctgaccctggaggacagtgagctgggctctggg
aacttcgggaccgtgaagaagggctactaccagatgaaaaaagtcgtgaagacagtggct
gtgaagattctgaagaacgaggccaatgaccctgctcttaaagacgagttattagcagag
gcgaacgtcatgcagcagctcgataacccttacatcgtgcgcatgatcgggatatgtgaa
gccgagtcctggatgctggtcatggagatggcggaactggggccactcaataaatactta
cagcagaacaggcacgtcaaggataagaacatcatagagctggttcatcaggtttctatg
ggaatgaaatatctggaggagtgcaattttgtgcacagagatctggctgcaagaaacgta
ttgctggttactcaacattatgccaagattagtgatttcggactttccaaagcactccgt
gctgacgaaagctactataaggcccagacccacgggaagtggccggtgaagtggtacgct
ccggagtgcattaactactacaagttctccagcaagagcgacgtctggagctttggcgtg
ctgatgtgggaggcgttctcctacggccagaagccctaccggggcatgaaaggaagtgaa
gtttcggctatgctggagaaaggggagaggatggggtgccccgcgggatgtccgagggag
atgtacgagctgatgaagctgtgctggacatatgaggtggagaagaggcccggcttcgaa
aacgtggagctgcgtctgcgcaattactactatgacgtggtgaactaa
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