Ursus maritimus (polar bear): 103663548
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Entry
103663548 CDS
T03271
Symbol
PDE8B
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr00230
Purine metabolism
umr01100
Metabolic pathways
umr04927
Cortisol synthesis and secretion
umr04934
Cushing syndrome
umr05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
103663548 (PDE8B)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
103663548 (PDE8B)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
103663548 (PDE8B)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
103663548 (PDE8B)
Enzymes [BR:
umr01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
103663548 (PDE8B)
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PAS_9
PAS
PAS_3
PAS_4
PAS_8
DUF3757
DUF4194
DHH
Motif
Other DBs
NCBI-GeneID:
103663548
NCBI-ProteinID:
XP_040478089
UniProt:
A0A8M1FBA6
LinkDB
All DBs
Position
Unknown
AA seq
797 aa
AA seq
DB search
MQDFPKREPESSVDPQAPSRAGSSVKVSSAEVRIGPMRLTQDPIQVLLIFAKEDSQSDGF
WWACDRAGYRCNIARTPESALECFLDKHHEIIVIDHRQTRNFDAEAVCRSIRATNPSEHT
VILAVVSQALGDREEASVLPLLHAGFNRRFMENSNIIACYNELIQIEHGEVRSQFKLRAC
NSVFTALDHCHEAIEITSDDHVIQYVNPAFERMMGYHKGELLGKELAELPKSDKNRADLL
DTINTCIKKGKEWQGVYYARRKSGDSIQQHVKITPVIGQGGKIRHFVSLKKLCCTTDNNK
QLHKLHRDSGDNSQTESHSLRYKNRRKESIDVKSISSRGSDAPSLQNRRYPSMARIHSMT
IEAPITKVINIINAAQENSPVTVAEALDRVLEILRTTELYSPQLGTKDEDPHTSDLVGGL
MTDGLRRLSGNEYVFTKNVHQSHSHLAMPITINDVPPCIAQLLDNEESWEFNIFELEAVT
HKRPLVYLGLKVFSRFGVCEFLHCSETTLRAWLQVIEANYHSSNAYHNSTHAADVLHATA
FFLGKERVKGSLDQLDEVAALIAATVHDVDHPGRTNSFLCNAGSELAVLYNDTAVLESHH
TALAFQLTVKDSKCNIFKNIDRNHYRTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPMA
AESEGSDCECNPTGKNFPENQILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTD
EEKRQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFAHLPALMQHLADNYKHW
KTLDDLKCKSLRLPSDS
NT seq
2394 nt
NT seq
+upstream
nt +downstream
nt
atgcaggactttccaaaaagggagccagagagttcagtggacccccaagctccttctcgt
gctggaagttcagtcaaggtctcatctgcggaggtgcgcattgggcccatgagactgaca
caggatcctattcaggttttgctgatctttgcaaaggaagatagtcagagtgatggattc
tggtgggcctgtgacagagctggttatagatgcaatattgctcggactccagagtcagcc
cttgaatgctttctagataaacatcatgaaattatcgtaatagatcacagacagactcga
aactttgatgcagaagcggtgtgcaggtcgatccgggccacaaatccttccgagcacacg
gtgatccttgcggtggtttcacaagcattgggtgaccgtgaagaggcctcagtcctccct
ctcctgcatgcaggcttcaacaggagatttatggagaatagcaacataattgcttgctat
aatgaactgattcaaatagaacacggggaagttcgctcacagttcaaactacgggcctgt
aattcggtgtttacggcattagaccactgtcatgaagccatagaaattacaagcgatgac
catgtgattcagtacgtcaacccagcctttgaaaggatgatgggctaccacaaaggcgag
ctgctggggaaagagctcgctgagctgcccaaaagtgataagaaccgggccgaccttctc
gacaccatcaacacatgcatcaagaagggcaaggagtggcagggggtttactatgccaga
cggaaatccggggacagcatccaacagcacgtgaagatcaccccggtgattggccaagga
gggaaaattaggcattttgtctccctcaagaaactgtgttgtaccactgacaataataag
cagcttcacaagcttcatcgtgattcaggagacaattctcagacagagtctcattcactc
agatacaagaacagaaggaaagagtccattgatgtgaaatcgatatcctctcgaggcagt
gatgcaccaagcctacagaaccgtcgctatccatccatggcaaggatccattccatgacc
atcgaggctcccatcacaaaggttataaatataatcaatgcagcccaagagaacagcccc
gtcacagtagcagaagccttggacagagttttagaaattttacggaccacagaactgtat
tcccctcagctgggtaccaaagatgaagatccccacaccagcgatcttgttggaggcctg
atgactgatggcttgagaaggttgtcaggaaacgagtatgtattcactaagaatgtgcac
cagagtcacagtcaccttgcgatgccaataaccatcaacgatgtccccccttgtatcgct
caattacttgataatgaggaaagttgggagttcaacatctttgaattggaagctgttaca
cataaaaggccattggtttacctgggcttaaaggtattttctcggtttggagtatgtgaa
tttttacactgctctgaaactactcttcgggcctggctccaagtgattgaagccaactac
cactcctccaatgcctaccataactccacccatgccgccgatgtcctgcacgccactgct
ttcttccttggaaaggaacgagtgaagggaagcctcgatcagctggatgaggtggcagcg
ctgattgccgccacagtccacgatgtggatcacccggggaggaccaactcgttcctgtgc
aacgcaggcagtgaactggctgtgctctataacgacactgctgtcttggagagtcaccac
accgccctggctttccagctcacagtcaaggacagcaaatgcaacattttcaagaatatc
gacaggaaccattatcggacactgcgccaggctattattgacatggtgttagcaacggag
atgaccaaacactttgaacatgtgaacaaatttgtgaacagcatcaataagccaatggca
gctgagagcgagggcagcgactgtgaatgcaaccctactgggaagaactttccggaaaac
caaatcctgatcaaacgtatgatgataaagtgtgctgatgtagccaacccatgtcgcccc
ctggacctgtgcatcgaatgggctgggaggatctcggaggagtactttgcacagactgat
gaagagaagagacaggggctccctgtggtgatgccagtgtttgaccggaatacctgcagc
atccccaaatcccaaatctccttcattgactacttcataacagacatgtttgatgcttgg
gatgcctttgcccatctgccagccctgatgcaacatttggctgataactacaaacactgg
aagacattagatgacctcaagtgcaaaagtctgaggcttccatctgacagctaa
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