| Entry |
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| Symbol |
PRKAA1
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| Name |
(RefSeq) 5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X1
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| KO |
| K07198 | 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31] |
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| Organism |
umr Ursus maritimus (polar bear)
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| Pathway |
| umr04213 | Longevity regulating pathway - multiple species |
| umr04920 | Adipocytokine signaling pathway |
| umr04932 | Non-alcoholic fatty liver disease |
| umr05418 | Fluid shear stress and atherosclerosis |
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| Brite |
KEGG Orthology (KO) [BR:umr00001]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
103664677 (PRKAA1)
04068 FoxO signaling pathway
103664677 (PRKAA1)
04151 PI3K-Akt signaling pathway
103664677 (PRKAA1)
04152 AMPK signaling pathway
103664677 (PRKAA1)
04150 mTOR signaling pathway
103664677 (PRKAA1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
103664677 (PRKAA1)
09144 Cellular community - eukaryotes
04530 Tight junction
103664677 (PRKAA1)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
103664677 (PRKAA1)
04922 Glucagon signaling pathway
103664677 (PRKAA1)
04920 Adipocytokine signaling pathway
103664677 (PRKAA1)
04921 Oxytocin signaling pathway
103664677 (PRKAA1)
09149 Aging
04211 Longevity regulating pathway
103664677 (PRKAA1)
04213 Longevity regulating pathway - multiple species
103664677 (PRKAA1)
09159 Environmental adaptation
04710 Circadian rhythm
103664677 (PRKAA1)
04714 Thermogenesis
103664677 (PRKAA1)
09160 Human Diseases
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
103664677 (PRKAA1)
05410 Hypertrophic cardiomyopathy
103664677 (PRKAA1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
103664677 (PRKAA1)
04932 Non-alcoholic fatty liver disease
103664677 (PRKAA1)
04931 Insulin resistance
103664677 (PRKAA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:umr01001]
103664677 (PRKAA1)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:umr04131]
103664677 (PRKAA1)
03029 Mitochondrial biogenesis [BR:umr03029]
103664677 (PRKAA1)
Enzymes [BR:umr01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.31 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase
103664677 (PRKAA1)
Protein kinases [BR:umr01001]
Serine/threonine kinases: CAMK group
CAMKL family
103664677 (PRKAA1)
Membrane trafficking [BR:umr04131]
Autophagy
Other autophagy associated proteins
Others
103664677 (PRKAA1)
Mitochondrial biogenesis [BR:umr03029]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
103664677 (PRKAA1)
Mitophagy factors
Other mitophagy factors
103664677 (PRKAA1)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
574 aa
MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNR
QKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNG
RKSDVPGVVRTGSMKELDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAK
IADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPF
DDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPK
YLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIM
NEAKDFYLATSPPDSFLDDHHFTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKA
KWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQV
DSRTYLLDFRSIDDEITEAKSGTATPQRSGSVSNYRSCQRNDSDAEAQGKSSEASLTSSV
TSLDSSPVDLTPRPGSHTIEFFEMCANLIKILAQ |
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| NT seq |
1725 nt +upstreamnt +downstreamnt
atgcgcagactcagttcctggagaaagatggcgacagccgagaagcagaaacacgacggg
cgggtgaagatcggccactacatcctgggggacacccttggcgtcggcaccttcggcaaa
gtgaaggttggcaaacatgaattgactggacataaagttgctgtgaagatactcaatcga
cagaagattcgaagccttgatgtggtaggaaaaatccgcagagaaattcagaacctcaag
cttttcaggcatcctcatataattaaactgtaccaggtcatcagtacaccatctgatatt
ttcatggtgatggaatatgtctcaggaggagagctatttgattatatctgtaaaaatgga
aggaaatctgatgtacctggagtagtaagaacaggctccatgaaggagctggatgagaaa
gaaagtcggcgtctgtttcaacagatcctttctggtgtggattactgtcacaggcatatg
gtggtccatagagatctgaaacctgaaaatgtcctgcttgatgcacacatgaatgcaaag
atagctgattttggtctttcaaacatgatgtcagatggtgaatttttaagaacaagttgc
ggctcacccaactatgctgcaccagaagtaatttcaggaagattgtatgcaggtccagag
gtagatatatggagcagtggggttattctctatgctttattatgtggaacccttccattt
gatgatgatcatgtgccaactctttttaagaagatatgtgatgggatcttttatacccct
cagtatttaaatccgtctgtgattagccttttgaaacatatgctacaggtggatcccatg
aagagggccacaatcaaagatatcagggaacatgaatggtttaaacaagatcttccaaaa
tatctttttcccgaggatccatcatacagttcaaccatgattgatgatgaagccttaaaa
gaagtatgtgaaaaatttgagtgctcagaagaggaggttctgagctgcctttataacaga
aatcaccaggaccctttggcagttgcctaccacctcataatagataacaggagaataatg
aatgaggccaaagatttttacttggcgacaagcccacctgattcttttctcgatgatcac
cacttcactcggccccatcctgaaagagtaccattcttggttgctgaaacaccaagagca
cgccacaccctcgatgaattaaatccacagaaatccaaacaccaaggtgtaaggaaagca
aaatggcatttgggaattagaagtcaaagtcgaccgaatgatatcatggcagaagtttgt
agagcaattaaacagctggattatgaatggaaggttgtaaacccctattatttgcgtgtt
cgaaggaagaatcctgtgacaagtacatactccaaaatgagtctgcagttataccaagtg
gatagtagaacatacttactggatttccgtagtattgatgatgaaattactgaagccaaa
tcagggactgctactccacagagatcgggatcagtaagcaactatcgatcttgccaaagg
aatgattcagatgctgaggctcaaggaaaatcctcagaagcttctcttacctcatctgtg
acctcacttgactcttctcctgttgacttaacaccaagacctggaagtcacacaatagaa
ttttttgagatgtgtgcgaatctaattaaaattcttgcacagtaa |
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