Ursus maritimus (polar bear): 103665409
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Entry
103665409 CDS
T03271
Symbol
SOS2
Name
(RefSeq) son of sevenless homolog 2 isoform X1
KO
K03099
son of sevenless
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr01521
EGFR tyrosine kinase inhibitor resistance
umr01522
Endocrine resistance
umr04010
MAPK signaling pathway
umr04012
ErbB signaling pathway
umr04014
Ras signaling pathway
umr04062
Chemokine signaling pathway
umr04068
FoxO signaling pathway
umr04072
Phospholipase D signaling pathway
umr04150
mTOR signaling pathway
umr04151
PI3K-Akt signaling pathway
umr04510
Focal adhesion
umr04540
Gap junction
umr04630
JAK-STAT signaling pathway
umr04650
Natural killer cell mediated cytotoxicity
umr04660
T cell receptor signaling pathway
umr04662
B cell receptor signaling pathway
umr04664
Fc epsilon RI signaling pathway
umr04714
Thermogenesis
umr04722
Neurotrophin signaling pathway
umr04810
Regulation of actin cytoskeleton
umr04910
Insulin signaling pathway
umr04912
GnRH signaling pathway
umr04915
Estrogen signaling pathway
umr04917
Prolactin signaling pathway
umr04926
Relaxin signaling pathway
umr04935
Growth hormone synthesis, secretion and action
umr05034
Alcoholism
umr05160
Hepatitis C
umr05161
Hepatitis B
umr05163
Human cytomegalovirus infection
umr05165
Human papillomavirus infection
umr05200
Pathways in cancer
umr05205
Proteoglycans in cancer
umr05206
MicroRNAs in cancer
umr05207
Chemical carcinogenesis - receptor activation
umr05208
Chemical carcinogenesis - reactive oxygen species
umr05210
Colorectal cancer
umr05211
Renal cell carcinoma
umr05213
Endometrial cancer
umr05214
Glioma
umr05215
Prostate cancer
umr05220
Chronic myeloid leukemia
umr05221
Acute myeloid leukemia
umr05223
Non-small cell lung cancer
umr05224
Breast cancer
umr05225
Hepatocellular carcinoma
umr05226
Gastric cancer
umr05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103665409 (SOS2)
04012 ErbB signaling pathway
103665409 (SOS2)
04014 Ras signaling pathway
103665409 (SOS2)
04630 JAK-STAT signaling pathway
103665409 (SOS2)
04068 FoxO signaling pathway
103665409 (SOS2)
04072 Phospholipase D signaling pathway
103665409 (SOS2)
04151 PI3K-Akt signaling pathway
103665409 (SOS2)
04150 mTOR signaling pathway
103665409 (SOS2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
103665409 (SOS2)
04540 Gap junction
103665409 (SOS2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
103665409 (SOS2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
103665409 (SOS2)
04660 T cell receptor signaling pathway
103665409 (SOS2)
04662 B cell receptor signaling pathway
103665409 (SOS2)
04664 Fc epsilon RI signaling pathway
103665409 (SOS2)
04062 Chemokine signaling pathway
103665409 (SOS2)
09152 Endocrine system
04910 Insulin signaling pathway
103665409 (SOS2)
04912 GnRH signaling pathway
103665409 (SOS2)
04915 Estrogen signaling pathway
103665409 (SOS2)
04917 Prolactin signaling pathway
103665409 (SOS2)
04926 Relaxin signaling pathway
103665409 (SOS2)
04935 Growth hormone synthesis, secretion and action
103665409 (SOS2)
09156 Nervous system
04722 Neurotrophin signaling pathway
103665409 (SOS2)
09159 Environmental adaptation
04714 Thermogenesis
103665409 (SOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103665409 (SOS2)
05206 MicroRNAs in cancer
103665409 (SOS2)
05205 Proteoglycans in cancer
103665409 (SOS2)
05207 Chemical carcinogenesis - receptor activation
103665409 (SOS2)
05208 Chemical carcinogenesis - reactive oxygen species
103665409 (SOS2)
05231 Choline metabolism in cancer
103665409 (SOS2)
09162 Cancer: specific types
05210 Colorectal cancer
103665409 (SOS2)
05225 Hepatocellular carcinoma
103665409 (SOS2)
05226 Gastric cancer
103665409 (SOS2)
05214 Glioma
103665409 (SOS2)
05221 Acute myeloid leukemia
103665409 (SOS2)
05220 Chronic myeloid leukemia
103665409 (SOS2)
05211 Renal cell carcinoma
103665409 (SOS2)
05215 Prostate cancer
103665409 (SOS2)
05213 Endometrial cancer
103665409 (SOS2)
05224 Breast cancer
103665409 (SOS2)
05223 Non-small cell lung cancer
103665409 (SOS2)
09172 Infectious disease: viral
05161 Hepatitis B
103665409 (SOS2)
05160 Hepatitis C
103665409 (SOS2)
05163 Human cytomegalovirus infection
103665409 (SOS2)
05165 Human papillomavirus infection
103665409 (SOS2)
09165 Substance dependence
05034 Alcoholism
103665409 (SOS2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
103665409 (SOS2)
01522 Endocrine resistance
103665409 (SOS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
RHG20_PH
PH_19
IQ_SEC7_PH
PH_10
PH_13
Motif
Other DBs
NCBI-GeneID:
103665409
NCBI-ProteinID:
XP_040476809
UniProt:
A0A8M1F7N0
LinkDB
All DBs
Position
Unknown
AA seq
1332 aa
AA seq
DB search
MQQAPQPYEFFSEENSPKWRGLLVPALRKVQEQVHPNLSANEESLYYIEELIFQLLNKLC
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLVSLCEDEPRSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRKLFKPSDI
DRIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI
LSPKFNEHFSKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKA
CSEEQEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPGDPVCPFYNRQLRSKHLAIKKM
NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHSQSRLPG
YSSAEYRLKEKFVMRKIQICDKEDTCECKHAFELVSKDENSIIFAAKSAEEKNNWMAALI
SLHYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNLQSRSGIPIIK
GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADKLA
VEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVR
GKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPPAIEWHISRPGQFETFDLMTLHPI
EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA
ENFEERVAILSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRRILD
EAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRR
KVAEITGEIQQYQNQPYCLRIEPEMRRFFENLNPMGSASEKEFTDYLFNKSLEIEPRNCK
QPPRFPRKSTFSLKSPGIRPNAGRHGSTSGTLRGHPTPLEREPCKMSFSRIAETDIESTV
SAPTSPNTPSTPPVSASSDLSVFLDVDLSSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLS
EEPLIPPPLPPRKKFDDDASNCKGNTKSDDDPPAIPPRQPPPPKVKPRVPAPTGAFDGPL
HSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHLHRDPDWFRDVSTCPNSPN
TPPSTPSPRVPRRCYVLSSSHNNLAHPQAPPVPPRQNSSPHLPKLPPKTYKRELSHPPSY
RLPLLENAETPQ
NT seq
3999 nt
NT seq
+upstream
nt +downstream
nt
atgcagcaggcgccgcagccgtacgagttcttcagcgaagaaaacagtccgaaatggcgg
ggactgctggtcccggccctgcggaaggttcaggagcaagtacatcccaatctctcagct
aatgaagagtctctgtattatattgaagagctgatttttcagctgcttaataaattatgc
atggctcaaccaaggactgttcaagatgtggaggaacgtgttcaaaagacctttcctcat
ccaattgataaatgggctattgctgatgcacaatctgccatagaaaaacgaaaacgaaga
aatcctctcttactgcctgtggacaaaatccatccttcattgaaggaagttttagggtac
aaagtggactatcatgtatccctatatattgtggctgtgctagagtatatctcagctgat
attttgaagttggctggtaattatgtttttaatatccgacattatgaaatatctcagcag
gacattaaagtgtcaatgtgtgcagataaggttttgatggacatgtttgatcaggatgac
ataggtttggtttctctctgtgaagacgagcctcgttcttcaggtgaattaaactactat
gaccttgtcagaaccgaaattgcagaagaaaggcagtatctacgggaactaaatatgatc
attaaagtgtttcgagaagcctttctttctgacagaaagctgtttaaaccttctgatatt
gacaggattttcagtaacatttcagatatacatgaattaactgtgaaacttttaggtttg
attgaagacacagttgaaatgactgatgaaagcagtcctcatccgttagcgggcagctgt
tttgaagatttggcagaagagcaagcatttgatccttatgaaacattatcacaggacatt
ctttctccaaaatttaatgaacatttcagtaagttgatggccagacctgcggtggctcta
cactttcagtccattgctgatggttttaaagaggcagttcgttatgtccttccacgcctt
atgctggtgcctgtttatcattgttggcactattttgaattattaaagcaattgaaagca
tgtagtgaagagcaggaagacagagaatgtttgaaccaagctattaccgctcttatgaat
ctccaaggtagtatggaccggatttacaagcagtattcacctagacgccgacctggcgat
cctgtttgccctttttataatcgtcaattaagaagcaagcatctggctattaaaaaaatg
aatgaaattcagaaaaacatagacggatgggaaggcaaagatattggacagtgttgtaat
gaattcattatggaaggcccattgacacgaattggtgctaaacatgaacgacatattttt
ctcttcgatggcttaatgattagctgtaaacccaatcatagtcagtcacgccttccaggt
tatagtagtgcagaatacagattaaaagagaaatttgtcatgaggaaaatacaaatatgt
gataaagaagatacttgtgagtgcaaacatgcttttgagttggtatccaaagatgaaaac
agcataatatttgctgctaagtctgccgaagagaaaaacaattggatggccgcgcttatt
tctcttcactatcgtagtacactagatcgaatgctagattcagtgttattgaaagaagaa
aatgagcaaccactgagattaccaagtcctgaagtgtatcgttttgtggtaaaagactct
gaggaaaacattgtttttgaagacaacctgcaaagtagaagtggaatccccattattaaa
ggaggaactgtagtgaaattaattgaaaggttaacatatcatatgtatgcagatcccaat
tttgttcgtacttttcttactacataccgttcattttgtaaaccacaggaattgctaagc
ttactgattgaacgatttgaaattccagagccagaacctactgaagcagataaattggcc
gtagagaaaggcgaacagccaatcagtgcagaccttaaaaggtttcgcaaggaatatgtc
caaccagtacaacttaggatcttaaatgtgtttcggcactgggttgaacaccatttttat
gactttgaaagggatttggaattgcttgaaagactagaatccttcatttcaagtgtaaga
gggaaagctatgaagaagtgggtagagtcaattgctaagatcatcaagagaaagaaacaa
gctcaggcaaatggaataagccataatattacctttgaaagtccacctccagcaattgaa
tggcatatcagcagaccaggacagtttgaaacatttgatctcatgacccttcatccaata
gaaattgcacgtcagctgacgcttttggaatctgatctctacaggaaagtccaaccttct
gaactagtagggagtgtatggacgaaagaagataaagaaataaattctccaaatttatta
aaaatgattcgccataccacaaacctcaccttatggtttgaaaagtgcattgtggaagca
gaaaattttgaggaacgggtggcaatactaagcagaattatagaaattctgcaagttttt
caagatttgaataacttcaatggtgtattggagatagtcagtgcagtaaattcagtgtcg
gtatacagactagaccatacttttgaggcattgcaggaaagaaaaaggagaattttggat
gaagctgtggagttaagtcaagatcactttaaaaaatacctagtaaaactgaagtcaatc
aatccaccttgtgtgcctttttttggaatatatttaacaaatatcctgaaaactgaagaa
gggaataatgattttttaaaaaagaaaggaaaagatttaatcaatttcagtaagaggagg
aaagtagctgaaattactggagaaattcagcagtatcagaatcaaccttactgtttacgg
atagaaccagaaatgaggaggttctttgaaaaccttaaccccatgggaagtgcttctgaa
aaggagtttacagattatttgttcaacaagtcactagaaattgaaccccgaaactgcaaa
cagccacctcgatttcctaggaaatcaactttctctttaaaatctcctggaatacggcct
aatgcaggccgacatggctctacctcaggcactttacgaggtcatccaacgccattagaa
agagaaccatgtaaaatgagctttagtcggattgctgaaactgatattgaatcaactgtg
tcagcaccaacctctccaaatacaccatctactccaccagtatctgcttcttcagacctt
agtgtgtttttagatgtggacctcagcagttcctgtggcagcaatagcatctttgctcca
gtcctcttgccacattcaaaatctttcttcagttcatgtggtagtttacataaactaagt
gaagagccactgattcctcctccacttcctcctcgaaaaaagtttgacgacgatgcttca
aactgcaagggaaacacgaaatctgatgatgacccccctgctattccaccaagacagcct
cctcctccaaaggtaaaacccagagttcctgctcctactggtgcatttgatgggcctctg
cacagtccacctccaccgccaccaagagatcctcttcctgatacccctccaccagttccc
cttcggcctccagaacactttataaactgtccgtttaatcttcagccacctccactagga
catcttcacagagatccagactggttcagagatgttagtacctgtccaaactcgccaaat
actcctcctagcacaccctctccgagagtaccacgtcgatgctacgtgctcagttccagt
cacaacaaccttgctcatcctcaagctccccctgttccaccaaggcagaattcaagccct
cacctaccaaaactgccaccaaagacttacaaacgggagctttcgcaccctccatcatac
agactgcctttgctagaaaatgcggaaactcctcagtga
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integrated database retrieval system
