KEGG   Ursus maritimus (polar bear): 103665687
Entry
103665687         CDS       T03271                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr04010  MAPK signaling pathway
umr04015  Rap1 signaling pathway
umr04218  Cellular senescence
umr04380  Osteoclast differentiation
umr04620  Toll-like receptor signaling pathway
umr04664  Fc epsilon RI signaling pathway
umr04668  TNF signaling pathway
umr04750  Inflammatory mediator regulation of TRP channels
umr04912  GnRH signaling pathway
umr04935  Growth hormone synthesis, secretion and action
umr04936  Alcoholic liver disease
umr05014  Amyotrophic lateral sclerosis
umr05022  Pathways of neurodegeneration - multiple diseases
umr05132  Salmonella infection
umr05135  Yersinia infection
umr05145  Toxoplasmosis
umr05161  Hepatitis B
umr05163  Human cytomegalovirus infection
umr05167  Kaposi sarcoma-associated herpesvirus infection
umr05169  Epstein-Barr virus infection
umr05170  Human immunodeficiency virus 1 infection
umr05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
umr05417  Lipid and atherosclerosis
umr05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:umr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103665687 (MAP2K6)
   04015 Rap1 signaling pathway
    103665687 (MAP2K6)
   04668 TNF signaling pathway
    103665687 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    103665687 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    103665687 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    103665687 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    103665687 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    103665687 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    103665687 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    103665687 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103665687 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    103665687 (MAP2K6)
   05161 Hepatitis B
    103665687 (MAP2K6)
   05163 Human cytomegalovirus infection
    103665687 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103665687 (MAP2K6)
   05169 Epstein-Barr virus infection
    103665687 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103665687 (MAP2K6)
   05135 Yersinia infection
    103665687 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    103665687 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    103665687 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    103665687 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103665687 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    103665687 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    103665687 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:umr01001]
    103665687 (MAP2K6)
Enzymes [BR:umr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     103665687 (MAP2K6)
Protein kinases [BR:umr01001]
 Serine/threonine kinases: STE group
  STE7 family
   103665687 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Choline_kinase Haspin_kinase CLP1_P DUF4344 APH
Other DBs
NCBI-GeneID: 103665687
NCBI-ProteinID: XP_008691912
UniProt: A0A384CAS3
LinkDB
Position
Unknown
AA seq 334 aa
MSQSKGRKRNPGLKIPKEAFEQPQPSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSEEFVDFTSQCLKKNSK
ERPTYPELMEHPFFTLHESKATDVASFVKLILGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaggaagcgaaaccctggccttaagattccaaaggaagcattt
gaacaacctcagcccagttccacgccacctcgagacttagactctaaagcttgcatttct
attggaaatcagaactttgaggtgaaggccgatgacctggagcccataatggaactgggg
cgaggtgcgtacggggtggtggagaagatgcgacacgtgcccagcgggcagatcatggcg
gtgaagcggatccgggccacagtaaatagccaggagcagaaaaggctactgatggatttg
gatatttccatgaggacagtggactgtcctttcaccgtcaccttttatggtgccctcttc
cgggagggtgacgtttggatctgtatggagctcatggatacgtcgctagataaattctac
aaacaagtgattgataaaggccaaacaattccagaggacatcttagggaaaatagctgtt
tctattgtaaaagcattagaacacttacacagtaagctctctgtcattcatcgagacgtc
aagccttccaacgtgctgatcaacactctgggccaagtgaagatgtgcgattttggaatc
agtggctaccttgtggactctgtggctaaaactattgatgcaggatgcaaaccgtacatg
gcccctgaaagaataaacccagagctcaatcagaagggctacagtgtgaagtctgacatt
tggagtctgggcatcacaatgattgagttggcaatccttcggtttccctacgactcttgg
ggaactcccttccagcagctcaaacaggtggtggaggaaccctcgccacaactcccggcg
gacaaattctctgaagagtttgttgactttacctcacagtgcttgaagaagaattccaaa
gaacggccgacatatccagaacttatggaacatccatttttcaccctgcacgaatccaaa
gcaacagacgtggcatcttttgtaaaactgattcttggagactaa

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