Ursus maritimus (polar bear): 103665746 Help Entry 103665746         CDS       T03271                                  Symbol ITGB4 Name (RefSeq) integrin beta-4   KO K06525   integrin beta 4 Organism umr  Ursus maritimus (polar bear) Pathway umr04151   PI3K-Akt signaling pathway umr04382   Cornified envelope formation umr04510   Focal adhesion umr04512   ECM-receptor interaction umr04810   Regulation of actin cytoskeleton umr04820   Cytoskeleton in muscle cells umr05165   Human papillomavirus infection umr05410   Hypertrophic cardiomyopathy umr05412   Arrhythmogenic right ventricular cardiomyopathy umr05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04151 PI3K-Akt signaling pathway     103665746 (ITGB4)   09133 Signaling molecules and interaction    04512 ECM-receptor interaction     103665746 (ITGB4)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     103665746 (ITGB4)   09142 Cell motility    04820 Cytoskeleton in muscle cells     103665746 (ITGB4)    04810 Regulation of actin cytoskeleton     103665746 (ITGB4)  09150 Organismal Systems   09158 Development and regeneration    04382 Cornified envelope formation     103665746 (ITGB4)  09160 Human Diseases   09172 Infectious disease: viral    05165 Human papillomavirus infection     103665746 (ITGB4)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     103665746 (ITGB4)    05412 Arrhythmogenic right ventricular cardiomyopathy     103665746 (ITGB4)    05414 Dilated cardiomyopathy     103665746 (ITGB4)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:umr04147]     103665746 (ITGB4)    04515 Cell adhesion molecules [BR:umr04515]     103665746 (ITGB4)    04090 CD molecules [BR:umr04090]     103665746 (ITGB4) Exosome [BR:umr04147]  Exosomal proteins   Exosomal proteins of colorectal cancer cells    103665746 (ITGB4)   Exosomal proteins of bladder cancer cells    103665746 (ITGB4) Cell adhesion molecules [BR:umr04515]  Integrins   Integrin beta subunits    103665746 (ITGB4) CD molecules [BR:umr04090]  Proteins   103665746 (ITGB4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Integrin_beta fn3 Calx-beta Integrin_B_tail Pur_ac_phosph_N Ig_DSCAM-DSCAML_C EGF_Teneurin PSI_integrin EGF_integrin I-EGF_1 EGF_2 EGF_TEN vWA_SIBA-E SEA Motif Other DBs NCBI-GeneID:  103665746 NCBI-ProteinID:  XP_008691997 UniProt:  A0A384CB00 LinkDB All DBs Position Unknown AA seq 1758 aa AA seqDB search MAGPCPSPWTRLLLAVLLSVSFPGEMANRCKRAQVKSCTECIRVDRECAYCTDEMFKERR CNTQAELLAAGCLWESMVVMESSFEITEDTQINTNLRRSQVWPQGLRVRLRPGEERHFEL KVFEPRESPMDLYILMDFSNSMSDDLDNLKQMGERLAQVLSELTDDYTIGFGKFVDKVSV PQTDMRPEKLKEPWPNSDPPFSFKNVISLTENLEEFRNKLLGERISGNLDAPEGGFDAIL QVAVCTRNIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDEACHLDSSGTYTKYK MQDYPSVPTLVPRHPPSLPPSLPPFCLLLSLLSFPKRLAPPRLHTYFPVSSLGVLQEDSS NIVELLQEAFNRIRSNLDIRALESPRGLRTEVTSEEFQKTNTGSFHIQRGEVGTYQVHLR AVEAVDGTHVCQLGEEDQKGNIHLKPSFSDGLWMDAGIICDVCPCELQKEELSARCNYHG DFVCGHCVCSEGWSGKTCSCSTGSLSDIKPCLREDEDKPCSGRGECQCGHCVCYGEGRYE GPFCEYDNFQCPRASGVLCNDRGRCSMGQCVCEPGWTGLSCDCPLSNATCIDSSGGICNG RGYCECGRCHCNQQSLYTDTICEINYSAIRLGLCEDLRSCVQCQAWGTGEKKGRTCEECS FKVKMVDELKKAEDVVEHCSFRDEEDDCTYSYTVEGDGAPGPNSTVLVHRKKDCPPRSFW WLIPLLIFLLLLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASD HLDTPMLRSGNLKGRDTVRWKITNNVQRPGFATHTSSTNPTELVPYGLSLRLARLCTENL LKPDTRECNQLRQEVEENLNEVYRQITDAHKLQQTKFRQQPNAGKKQDHTIVDTVLLAPR SAKQALLKLTEKHVEQGSFHELKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRP EDDDEKQLLVEAIDVPMGTATLGRRLVNITIIKEQASGIVSFEKPEYTVSGGEQVARIPV VRRILDNGKSQVSYRTQDNTAQGNRDYIPAEGELLFQPGETWKELHVKLLELQEMDSLLR GRQTRRFHIQLTNPKFGARLGQPHSATVIIGDPDELDRNFTSQTLSSFPPHGDLGAPQNS NAKAAGSRKILFNWLPPPGKPTGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYE MKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAY EVCYGLVNEDNRPIGPMKKVLVDSPKRRMLLIENLRESQPYRYTVKARNGAGWGPEREAI INLATQPKRPMSIPIIPDIPIVDAQCGEDYESFLMYSDDVLRSPAGSQRPSVSDDTEHLV NGRMDFAFPGSANSLHRMTVANTAYGTHLSPHLSHRVLSTSSTLTRDYHSLTRTEHSHSA TLPRDYSTLTSLSSHNSRLAAGVPHTPTRLVFSALGPTSLKVSWQEPQCEQVLQGYSVEY QLLNGGELHQLNIPNPSQTSVVVEDLLPNHSYVFRVRAQSQEGWGPEREGIITIESQVHP QSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPDGNILGYLVTCEMAHGG EPATTFLVDGDSPESRLTVPGLSENVPYKFKVQAKTTEGYGPEREGIITIESQEGGPFPQ MGSHPGLFQHSLPGEYSSVTTTHTSTTEPFLLDGLTLGSQHLEAGGSLTRHVTQEFVSRT LTTSGTLSTQVDQQFFQT NT seq 5277 nt NT seq  +upstreamnt  +downstreamnt atggcaggaccgtgtcccagcccgtggaccaggctgctgctggcagtcctgctgagcgtc agcttccccggggagatggcaaaccgctgcaagagggcccaggtgaagagctgcacggag tgcatccgcgtggacagggagtgcgcctactgcacggacgagatgttcaaggagcggcgc tgcaacacccaggcagagctgctggctgcgggctgcctgtgggagagcatggtggtcatg gagagcagcttcgagatcacagaggacacccagatcaacaccaacttgagacgcagccag gtgtggccccagggcctacgggtccggctgcggccgggcgaggagcggcacttcgagctg aaggtgttcgagcccagggagagccctatggacctgtacatcctcatggacttctccaac tccatgtccgacgatctggacaacctcaagcagatgggggagcgactggcccaggtcctg agtgagctcaccgatgactacactattggatttggcaagtttgtggacaaagtcagcgtc cctcagacagacatgaggcctgagaagctgaaggagccctggcccaacagcgatcccccc ttctccttcaagaacgtcatcagcctgacggaaaacttggaagagtttcggaataaactg ctaggggagcggatctcaggcaacctggacgctcctgaaggaggcttcgatgccatcctg caggtggccgtgtgcacgaggaacattggctggcgccccgacagcacccatctgctggtg ttctccaccgagtccgctttccactacgaggcggacggtgccaacgtgctggccggcatc atgagccgcaatgacgaggcatgccacctggactcctcgggcacctacaccaagtacaag atgcaggactatccgtccgtgcccaccctggttcccagacatcctccctccctcccccct tccctccctcccttctgcctcctcctctcccttctttccttcccaaagcgtttggctccc ccaaggctgcacacctacttccccgtctcctcgctgggggtgctgcaagaggactcctcc aacattgtcgagttgctgcaggaagccttcaaccgcattcgttccaacctggacatccgg gccctggaaagcccccgaggcctgcggacagaggtcacctccgaagagttccaaaagacg aatactgggtcctttcacatccagcggggggaagtgggcacgtaccaggtgcacctgcgg gctgtggaggctgtggatgggactcacgtgtgccagctgggagaggaggaccagaagggc aacatccacctgaagccctccttctcagacggcctctggatggacgcaggcatcatctgc gacgtgtgtccgtgcgagctgcaaaaagaggagctttccgcccgctgcaactaccacgga gacttcgtgtgtggacactgcgtgtgcagtgagggctggagcggcaagacctgtagctgc tccacgggctcactgagtgacataaagccctgcctgcgggaggacgaggacaagccgtgc tccgggcgtggcgagtgccagtgcggccactgcgtgtgctatggagaaggccgctacgag ggtccattctgcgagtatgacaacttccagtgtccccgtgcctccggggtcctctgtaat gaccggggacgctgttccatgggccagtgcgtgtgtgagcctggctggacaggcttgagc tgcgactgtcctctcagcaatgccacttgcatcgacagcagtgggggcatctgtaatggg cgtggctactgcgagtgtggccgctgccactgcaaccagcagtcgctctacacggacacc atctgtgagatcaactactcagcgatccgcctgggcctgtgtgaggacctgcgctcctgt gtgcagtgccaagcctggggcaccggtgagaagaagggccgcacgtgcgaggagtgcagc ttcaaggtcaagatggtggacgagcttaagaaagcagaggacgtggtggagcactgctcc ttccgggatgaagaggatgactgcacgtacagctacacggtggagggcgacggcgccccc gggcccaacagcactgtcctggtgcacaggaagaaggactgcccacccaggtccttctgg tggctcatccctctgctcatcttcctcctgctgctcctggccctgctgctgctgctctgc tggaagtactgtgcctgctgcaaggcttgcctggctcttctcccttgctgcaaccgaggt cacatggtgggcttcaaggaagaccactacatgctacgggagaacctgatggcctcggac cacctggacacacccatgctgcgcagcgggaacctcaagggacgggacacggtccggtgg aagatcaccaacaacgtgcagcggcctggctttgccacccacacctccagcaccaacccc acggagctggtgccctacgggctgtccctgcgcctcgcccgcctatgcaccgagaacctg ctgaagcctgacacgcgagagtgtaaccagctgcgccaggaggtggaggagaacctgaat gaggtgtacagacagatcacagacgcacacaagctccagcagacgaagttccggcagcag cccaacgccgggaaaaagcaggaccacaccattgtggacacggtgctgttggcgccccgc tcagccaagcaggccttgctgaagctgacagagaagcatgtggaacagggctccttccac gagctcaaggtggccccaggctactacaccctcactgcagaccaggatgcccggggcatg gtggagttccaggagggcgtggagctagtagacgtgcgggtacccctcttcatccggccc gaggacgacgacgagaagcagctgctggtggaagccatcgacgtacccatgggcaccgcc accctcggccgccgcctggtgaacatcaccatcatcaaggagcaagccagcgggatagtg tcttttgagaagcccgagtacacagtcagcggtggggagcaagtggcccgcatccctgtc gtccggcgcatcctggacaatggcaagtcccaggtctcctaccgcacacaggataacact gcccagggcaaccgggactacatccccgcagagggtgagctgctgttccaacctggggag acctggaaggagctgcacgtgaagctcctggagctacaggagatggactccctcctgcgg ggccgccagacccgccgcttccacattcagctcaccaaccccaagttcggggcccgcctg ggccagccccactcagccactgtcatcattggggacccagacgaactggaccggaacttc acaagccagacactgtcatcattccctcctcatggtgacctgggtgccccacagaactcc aatgccaaggctgcggggtcccggaagatccttttcaactggctgccccctcctggcaag ccaacagggtacagggtcaagtactggatccagggtgactctgagtccgaagcccacctg cttgacagcaaggtgccctcggtggagctcaccaacctgtacccatattgtgactacgag atgaaggtgtgcgcctacggggcacagggcgagggcccctatagctccttggtgtcctgc cgcacccaccaggaagtacccagtgagccagggcgtctggccttcaatgtcgtctcctcc accgtgacccagctgagctgggctgagccggctgagaccaatggcgagatcacggcctac gaggtctgctacggcttggttaacgaggacaaccgacccatcgggcccatgaagaaggtg ttggtggacagtcccaagaggcggatgctgcttatcgagaaccttcgggagtcccagcca taccgctacacggtgaaggcgcgcaacggggcaggctggggccccgagcgggaggccatc atcaacctggccacccagcccaagcggcccatgtccatccccatcatcccagacatcccc attgtggacgcccagtgtggggaagactacgagagcttcctcatgtacagtgatgacgtt ctgcgctcccctgctggcagccagaggcccagcgtctccgatgacactgagcacctggtc aacgggcggatggactttgccttcccgggcagtgccaactccctgcacaggatgaccgtg gccaacaccgcctacggcacccacctgagcccacacctgtcccaccgggtgctgagtaca tcctccacgctcacgcgggactaccactcgctgacccgcacagagcattcgcactccgcc acgctgcctagagactactccaccctcacctccctctcctcccacaactcccgcttggct gccggtgtgccccacacacccacccgcctggtgttctcagcgctgggacccacgtctctg aaagtgagctggcaggagccacagtgcgagcaggtgttgcagggctatagcgtggagtac cagctgctgaacggcggggagctgcatcagctcaacatccccaaccccagccagacttca gtggtggtggaagaccttctgcccaaccattcctatgtgttccgtgtgcgggctcagagc caggaaggctggggcccagagcgcgagggcatcatcaccattgagtcgcaggtgcacccc cagagtccgctctgccccctaccaggctccgccttcaccctgagcacacccagtgccccg ggcccactggtgttcactgccctgagcccagactcgctgcagttgagctgggagcggcca cgcaggcccgatgggaatatccttggctacctggtgacctgtgagatggcccatggagga gagccagccaccacgttcctggtggatggggacagccctgagagtcggctgactgtgccg ggcctcagtgagaacgtgccctacaagttcaaggtgcaggccaagaccaccgaaggttac gggccagagcgtgagggcatcatcaccatcgagtctcaggagggaggccctttcccacaa atgggcagccaccctgggctcttccagcactcactgccaggcgaatacagcagcgtcacc accacccacaccagcaccaccgagcccttcctactggatggactgaccctggggtcccaa cacctggaagcaggtggctccctcacccgccacgtgacccaggagtttgtgagccggacg ctgaccaccagtggaaccctcagtacccaggtggaccaacagttcttccagacctga

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