Ursus maritimus (polar bear): 103665903
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Entry
103665903 CDS
T03271
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr04140
Autophagy - animal
umr04141
Protein processing in endoplasmic reticulum
umr04210
Apoptosis
umr04932
Non-alcoholic fatty liver disease
umr05010
Alzheimer disease
umr05012
Parkinson disease
umr05014
Amyotrophic lateral sclerosis
umr05016
Huntington disease
umr05017
Spinocerebellar ataxia
umr05022
Pathways of neurodegeneration - multiple diseases
umr05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
103665903 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
103665903 (ERN1)
09143 Cell growth and death
04210 Apoptosis
103665903 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
103665903 (ERN1)
05012 Parkinson disease
103665903 (ERN1)
05014 Amyotrophic lateral sclerosis
103665903 (ERN1)
05016 Huntington disease
103665903 (ERN1)
05017 Spinocerebellar ataxia
103665903 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
103665903 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
103665903 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
103665903 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
umr01001
]
103665903 (ERN1)
Enzymes [BR:
umr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
103665903 (ERN1)
Protein kinases [BR:
umr01001
]
Serine/threonine kinases: Other
IRE family
103665903 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
PQQ_3
Motif
Other DBs
NCBI-GeneID:
103665903
NCBI-ProteinID:
XP_040496332
UniProt:
A0A8M1GNI8
LinkDB
All DBs
Position
Unknown
AA seq
973 aa
AA seq
DB search
MPARLLLLALLLPGPGIFGSPSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPVL
QVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGKKQ
DIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYFDY
AASLPEDDGEYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLKKVMH
INVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMVHE
GVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKNKLNYLRNSWLLI
GHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVDQTSENAPTTISQDV
EEKYEHAPAKPEAPVDSMLKDIATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQFQKE
LEKIQLLQQQQLPFHPPGDVAQDAELLDSSGLYSESSGTSSPSTSPRASNHSLHSSGSAS
KAGASPFLEQDDEDEETSMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPE
CFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHLGLE
PITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVGRHS
FSRRSGVPGTEGWIAPEMLSEDCKDNPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQAN
ILLGAYSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQD
VSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAM
RNKKHHYRELPAEVRETLGSLPDDFVRYFTSRFPHLLSHTYRAMEPCSHERLFQPYYFHE
PPEPRPPVTPDIL
NT seq
2922 nt
NT seq
+upstream
nt +downstream
nt
atgccggcccggctgctgctgctggcgctgctgctgcccggccccgggatttttggaagt
cccagcacagtgacacttcctgaaaccttgttgtttgtgtcaactctggatggaagtttg
catgctgtcagcaagaggacaggctcaatcaaatggactttaaaagaagatcctgttctg
caggttccaacacatgtggaagagcctgctttcctcccagatcccaatgatggcagcctg
tatacgcttgggggcaagaataatgaaggcctgacgaaacttccttttaccatcccagag
ttggtgcaggcatccccatgccgaagttcagatggaattctctacatgggtaaaaagcag
gacatttggtacgttatcgatcttctgactggggagaagcagcagactttgtcatcggcc
tttgcagacagtctctgcccatcaacctctttgctgtatcttgggcgaacagagtacacc
atcaccatgtacgacaccaaaacccgagagctccggtggaacgccacctacttcgactac
gcagcctcgctgcctgaggacgacggggaatacaagatgtcccactttgtgtccaacggc
gatgggctggtggtgaccgtggacagtgaatctggcgacgtcctgtggatccaaaactac
gcttcccccgtggtggccttttacgtctggcagcgggagggtctgaagaaggtgatgcac
atcaacgtcgctgtggagaccctgcgctacctgaccttcatgtctggggaggtgggccgc
atcaccaagtggaagtacccgttccccaaggagacggaggccaagagcaagctgacgccc
accctgtatgttgggaaatactctaccagcctgtatgcctccccctccatggttcacgag
ggggttgccgttgtgccccgaggcagtactcttcctttgctggaaggcccccagaccgat
ggagtcaccattggggacaaaggggagtgtgtgatcacgcccagcacagacctcaagttt
gaccctgggctcaaaggcaagaacaagctcaactacctgaggaactcctggcttctgata
ggacaccatgaaacccccctgtctgcgtctaccaagatgctggagagattccccaacaat
ctgcccaaacatcgggaaaacgtgattcctgccgattcagagaagaagagctttgaggaa
gttatcaacctggttgaccagacttcagaaaacgcgcctaccaccatctcacaggatgtg
gaagagaaatacgagcatgcccctgccaagcccgaggcccccgtggactccatgctcaag
gacatcgccaccatcatcctgagcaccttcctgctcatcggctgggtggccttcatcatc
acctaccccttgagcatgcatcagcagcagcagctccagcaccagcagttccagaaggaa
ctagagaaaatccagctcctgcagcagcagcagctgcccttccatccacctggagacgtg
gctcaagatgctgagctcttggactcgtctggcctgtactccgagagctcaggcaccagc
agccccagcacgtcccccagagcctccaaccactcactccactccagtggctctgcctcc
aaggctggcgccagccccttcctggagcaggatgatgaggatgaggaaaccagcatggtg
atagtcgggaaaatttcattctgtcccaaggatgtgctgggtcacggagctgagggcacg
attgtgtaccggggcatgtttgacaaccgcgacgtggccgtcaagaggatcctccccgag
tgtttcagtttcgcagaccgggaagtccagctgcttcgagaatcggatgagcaccccaac
gtgatccgttacttctgcacggagagggaccggcagttccagtacattgccatcgagctg
tgtgcggccaccctgcaggagtacgtggagcagaaggactttgcccacctcggcctggag
cccatcaccttgctgcaacagaccacctcaggcctggcccatctgcactccctcaacatt
gttcacagagacctgaagccccacaacattctcctctccatgcccaacgcacatggcagg
atcaaggccatgatctcggacttcggcctctgcaagaagctggcggtcggcaggcacagt
ttcagccgccgctcaggagtgccgggcacagaaggctggattgctccagagatgctgagc
gaagactgcaaggacaacccgacctacacagtagacatcttctctgcgggctgtgtcttt
tactacgtgatatcggagggcagccacccttttggcaagtccctgcagcggcaggccaac
atcctcctgggtgcctacagcctcgactgcttgcaccccgagaagcacgaggatgtcatt
gcccgggaattaatagagaagatgatcgcaatggaccctcagaaacgcccttcggcgaag
cacgtgctgaaacacccgttcttctggagcctggaaaagcagctccagttctttcaggat
gtgagtgaccgaatagagaaggagtccctggacggcccgatagtgaagcagctggagcga
ggcgggagagctgtggtgaagatggactggagggagaacatcaccgtccccctgcagaca
gatctgcggaaattcagaacctataaaggtggctccgtccgagacctcctccgagccatg
agaaacaagaagcaccactaccgggagctccccgcggaggtgcgggagacgctgggctcc
ctccccgacgacttcgtgcgctacttcacgtcccgcttcccccacctcctgtcccacacc
taccgggccatggagccgtgcagccacgagcggctcttccagccctactacttccacgag
cccccagagccccggcctccagtgactccagacatcctttga
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integrated database retrieval system
