KEGG   Ursus maritimus (polar bear): 103667825
Entry
103667825         CDS       T03271                                 
Symbol
PPP3CB
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr04010  MAPK signaling pathway
umr04020  Calcium signaling pathway
umr04022  cGMP-PKG signaling pathway
umr04114  Oocyte meiosis
umr04218  Cellular senescence
umr04310  Wnt signaling pathway
umr04360  Axon guidance
umr04370  VEGF signaling pathway
umr04380  Osteoclast differentiation
umr04625  C-type lectin receptor signaling pathway
umr04650  Natural killer cell mediated cytotoxicity
umr04658  Th1 and Th2 cell differentiation
umr04659  Th17 cell differentiation
umr04660  T cell receptor signaling pathway
umr04662  B cell receptor signaling pathway
umr04720  Long-term potentiation
umr04724  Glutamatergic synapse
umr04728  Dopaminergic synapse
umr04921  Oxytocin signaling pathway
umr04922  Glucagon signaling pathway
umr04924  Renin secretion
umr05010  Alzheimer disease
umr05014  Amyotrophic lateral sclerosis
umr05020  Prion disease
umr05022  Pathways of neurodegeneration - multiple diseases
umr05031  Amphetamine addiction
umr05152  Tuberculosis
umr05163  Human cytomegalovirus infection
umr05166  Human T-cell leukemia virus 1 infection
umr05167  Kaposi sarcoma-associated herpesvirus infection
umr05170  Human immunodeficiency virus 1 infection
umr05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
umr05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:umr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103667825 (PPP3CB)
   04310 Wnt signaling pathway
    103667825 (PPP3CB)
   04370 VEGF signaling pathway
    103667825 (PPP3CB)
   04020 Calcium signaling pathway
    103667825 (PPP3CB)
   04022 cGMP-PKG signaling pathway
    103667825 (PPP3CB)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    103667825 (PPP3CB)
   04218 Cellular senescence
    103667825 (PPP3CB)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    103667825 (PPP3CB)
   04650 Natural killer cell mediated cytotoxicity
    103667825 (PPP3CB)
   04660 T cell receptor signaling pathway
    103667825 (PPP3CB)
   04658 Th1 and Th2 cell differentiation
    103667825 (PPP3CB)
   04659 Th17 cell differentiation
    103667825 (PPP3CB)
   04662 B cell receptor signaling pathway
    103667825 (PPP3CB)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    103667825 (PPP3CB)
   04921 Oxytocin signaling pathway
    103667825 (PPP3CB)
   04924 Renin secretion
    103667825 (PPP3CB)
  09156 Nervous system
   04724 Glutamatergic synapse
    103667825 (PPP3CB)
   04728 Dopaminergic synapse
    103667825 (PPP3CB)
   04720 Long-term potentiation
    103667825 (PPP3CB)
  09158 Development and regeneration
   04360 Axon guidance
    103667825 (PPP3CB)
   04380 Osteoclast differentiation
    103667825 (PPP3CB)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103667825 (PPP3CB)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    103667825 (PPP3CB)
   05170 Human immunodeficiency virus 1 infection
    103667825 (PPP3CB)
   05163 Human cytomegalovirus infection
    103667825 (PPP3CB)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103667825 (PPP3CB)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    103667825 (PPP3CB)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    103667825 (PPP3CB)
   05014 Amyotrophic lateral sclerosis
    103667825 (PPP3CB)
   05020 Prion disease
    103667825 (PPP3CB)
   05022 Pathways of neurodegeneration - multiple diseases
    103667825 (PPP3CB)
  09165 Substance dependence
   05031 Amphetamine addiction
    103667825 (PPP3CB)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103667825 (PPP3CB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:umr01009]
    103667825 (PPP3CB)
Enzymes [BR:umr01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     103667825 (PPP3CB)
Protein phosphatases and associated proteins [BR:umr01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     103667825 (PPP3CB)
SSDB
Motif
Pfam: Metallophos DUF5378
Other DBs
NCBI-GeneID: 103667825
NCBI-ProteinID: XP_008694268
UniProt: A0A384CHD8
LinkDB
Position
Unknown
AA seq 479 aa
MDGIPRVDVLKNHLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFF
DLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHL
TEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLD
RFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLS
IIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNC
SPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFDGSAAARKEII
RNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAEK
AIRGFSPPHRICSFEEAKGLDRINERMPPRKDAVQQDGFNSLNTAHATENHGTGNHSAQ
NT seq 1440 nt   +upstreamnt  +downstreamnt
atggatgggatacccagggttgatgttctgaagaaccacttagtaaaagaaggtcgggta
gatgaagaaattgcacttagaattatcaatgaaggtgctgccatccttcggagagagaaa
accatgatagaagtagaggctccaattacagtgtgtggtgacatccatggccaatttttt
gatctgatgaaactttttgaagtaggaggatcacctgctaatacacgatacctttttctt
ggtgattatgtggacagaggttattttagtatagagtgtgtcttatatttatgggtcctg
aagattctgtacccaagcacattatttcttctgagaggcaatcatgaatgcagacacctt
actgaatattttacctttaagcaggaatgtaaaattaaatattcagaaagagtctatgaa
gcttgtatggaagcttttgatagtctgcctcttgctgcacttttaaatcaacaatttctt
tgtgttcatggtggactttcaccagaaatacacacactggatgatattaggagattagat
agattcaaagagccacctgcatttggaccaatgtgtgacttgctatggtccgatccttct
gaagattttggaaatgaaaaatcacaggaacattttagtcacaatacagttcgaggatgt
tcttatttttataactatccagcagtgtgtgaatttttgcaaaacaataatttgttatcg
attattagagctcatgaagctcaagatgcaggctatagaatgtacagaaaaagtcaaact
acagggttcccttcattaataacaattttttcggcacctaattacttagatgtctacaat
aataaagctgctgtattaaagtatgaaaataatgtgatgaatattcgacagtttaactgt
tctccacatccttactggttgcccaattttatggatgtcttcacatggtctttaccattt
gttggagaaaaagtgacagaaatgttggtaaatgttctgagtatttgctctgatgatgaa
ctgatgactgaaggtgaagaccagtttgatggttcagctgcagcccggaaagaaatcata
agaaacaaaattcgagcaattggcaagatggcacgggtcttctctgttctcagggaggag
agtgaaagcgtgctgacactcaagggcctgactcccacagggatgttgcctagtggagtg
ttggctggaggacggcagaccctgcaaagtgccacagttgaggctattgaggctgaaaaa
gcaatacgaggattctctccaccacatagaatctgcagttttgaagaggcaaagggtttg
gataggatcaatgagagaatgccaccccggaaagatgctgtacagcaagatggtttcaat
tctctgaacaccgcacatgccactgagaaccacgggactggcaaccatagtgcccagtga

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