Ursus maritimus (polar bear): 103668697 Help Entry 103668697         CDS       T03271                                  Symbol PKLR Name (RefSeq) pyruvate kinase PKLR   KO K12406   pyruvate kinase isozymes R/L [EC:2.7.1.40] Organism umr  Ursus maritimus (polar bear) Pathway umr00010   Glycolysis / Gluconeogenesis umr00620   Pyruvate metabolism umr01100   Metabolic pathways umr01200   Carbon metabolism umr01230   Biosynthesis of amino acids umr04910   Insulin signaling pathway umr04930   Type II diabetes mellitus umr04932   Non-alcoholic fatty liver disease umr04950   Maturity onset diabetes of the young Module umr_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate umr_M00002   Glycolysis, core module involving three-carbon compounds Brite KEGG Orthology (KO) [BR:umr00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     103668697 (PKLR)    00620 Pyruvate metabolism     103668697 (PKLR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     103668697 (PKLR)  09160 Human Diseases   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     103668697 (PKLR)    04950 Maturity onset diabetes of the young     103668697 (PKLR)    04932 Non-alcoholic fatty liver disease     103668697 (PKLR)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:umr04147]     103668697 (PKLR) Enzymes [BR:umr01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.40  pyruvate kinase      103668697 (PKLR) Exosome [BR:umr04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    103668697 (PKLR) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK PK_C HpcH_HpaI IMPDH Motif Other DBs NCBI-GeneID:  103668697 NCBI-ProteinID:  XP_040491692 UniProt:  A0A8M1GAH5 LinkDB All DBs Position Unknown AA seq 574 aa AA seqDB search MSSQESIQAQELWSRISKSQRDLAKSILIGAPGGPAGYLRRASVAQLTHELGTAFFQRQQ LSAAMADSFLEHLCLLDIDSEPVAARSTSIIATIGPASHSVESLKEMIKAGMNIARLNFS HGSHEYHAQSIANIREAVESFATSPLGYRPVAIALDTKGPEIRTGVLQGGPEAEVELVKG SRVLVTVDPAFRTRGDANTVWVDYPNIVKVVPVGGRIYIDDGLISLQVKKIGLEGLETQV ENGGLLGSRKGVNLPGAEVDLPGLSEQDVLDLRFGVQHNVDIVFASFVRKASDVATIRAA LGPEGRNIKIISKIENHEGVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRC NLAGKPVVCATQMLESMIAKPRPTRAETSDVANAVLDGADCIMLSGETAKGRFPVEAVKM QHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRS AQLLSRYRPRAAVIAVTRSAQAARQAHLCRGVFPLLYSEPPEAIWADDVDRRVQFGIESG KLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSVS NT seq 1725 nt NT seq  +upstreamnt  +downstreamnt atgtccagccaggagagcatacaagcccaggagctttggtcaaggatctctaagtcccaa agggacttagcaaagtccatcctgattggggctccaggagggccggcggggtacctgagg cgggctagcgtggcccagctgacccacgagctgggcacggccttcttccagcggcagcag ctgtcggctgctatggcagacagcttcctggagcacctgtgcctcctggacatcgactcg gagcccgtggccgcccgcagtaccagcatcattgccaccatcgggccggcctctcactcg gtagagagcctcaaggagatgatcaaagccgggatgaacattgcgcgcctcaacttctcg cacggctcccacgagtaccacgctcagtccatcgccaacatccgggaggcggtggagagc tttgcaacttctcccctcggctaccgacccgtggccatcgccctggacaccaagggaccg gagatacgcaccggagtcctgcaggggggcccggaggccgaggtggagctagtgaagggc tcccgggtgctggtgaccgtggacccagcgttccggacaaggggggacgcgaacaccgtg tgggtggactaccccaatatcgtgaaggtcgtgccggtggggggccgcatctacatagac gacgggctcatctccctccaggtcaagaaaatcggcctggaggggctggagacccaagtg gagaacggaggcctcctgggcagccggaagggcgtgaacttgccaggcgccgaggtggac ttgcccgggctgtctgagcaagacgtcctggacttgcgcttcggggtgcagcataacgtg gacatcgtctttgcctccttcgtgcggaaagccagtgatgtggctaccatccgagctgct ctggggcctgaaggacgcaacatcaagatcattagcaaaatcgagaaccacgaaggcgtg aagaagtttgatgaaatcctggaggtgagcgatggcatcatggtggcacggggcgacctg ggcatcgagatcccagccgagaaggttttcctggcccagaagatgatgatcggacgttgc aacttggcgggcaagcccgtcgtctgcgccacacagatgctggagagcatgatcgcgaag ccgcggccgacccgggcagagacgagtgacgtagccaatgccgtgctggacggagccgac tgcatcatgctgtcgggcgagaccgccaagggccgatttcccgtggaggcggtgaagatg cagcacgcgatcgcccgggaggcggaggctgcggtgtaccaccggcagctgtttgaggaa ctgcgccgggcagcgcccctgagccgcgatcccactgaggtcactgccataggcgcggta gaggccgccttcaagtgctgtgctgccgccatcatcgtgctgaccacgactggccgctca gcacagctgctgtctcggtaccgacctcgggcagcagtcattgctgtcacccgttctgcc caggctgctcggcaggcccacctgtgccgaggggtcttccccttgctctacagtgaacct ccagaggccatctgggcagatgacgtggatcgccgggtccaatttggcattgaaagtgga aagctccgtggcttccttcgcgtgggggacctggtgatcgtggtgacaggctggcgacct ggctctggctacaccaacatcatgcgagtgctgagcgtctcctga

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