| Entry |
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| Symbol |
ABCC1
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| Name |
(RefSeq) multidrug resistance-associated protein 1 isoform X1
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| KO |
| K05665 | ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3] |
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| Organism |
umr Ursus maritimus (polar bear)
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| Pathway |
| umr04977 | Vitamin digestion and absorption |
| umr04981 | Folate transport and metabolism |
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| Brite |
KEGG Orthology (KO) [BR:umr00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
103668839 (ABCC1)
09132 Signal transduction
04071 Sphingolipid signaling pathway
103668839 (ABCC1)
09150 Organismal Systems
09154 Digestive system
04977 Vitamin digestion and absorption
103668839 (ABCC1)
04981 Folate transport and metabolism
103668839 (ABCC1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
103668839 (ABCC1)
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
103668839 (ABCC1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:umr02000]
103668839 (ABCC1)
Enzymes [BR:umr01000]
7. Translocases
7.6 Catalysing the translocation of other compounds
7.6.2 Linked to the hydrolysis of a nucleoside triphosphate
7.6.2.3 ABC-type glutathione-S-conjugate transporter
103668839 (ABCC1)
Transporters [BR:umr02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
103668839 (ABCC1)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
1583 aa
MALRGFCSADGSDPFWAWDVTWNTSNPDFTKCFQNTFLVWVPCSYLWVCFPFYFLYLSRH
DRGYIQMTYLNKTKTALGFLLWIVCWADLFYSFWERSWGKFLAPVFLVSPTLLGITMLLA
TFLIQLERRKGVQSSGIMLTFWLVALLCALAILRSKIMTALKEDAEIDVFRDVTFYIYFS
LVLMQLVLSCFSDRPPLFSETIHDPNPCPESSASFLSRVTFWWITGLMVRGYRQPLESTD
LWSLNKEDTSEQVVPVLVKNWKKECAKSKRQQAKMAYSSKDPAKPKGGSQVDVNEEAEVL
IVKSPQKEREPSLFKVLYKTFGPYFLMSFLFKALHDLMMFAGPEILKLLINFVNDQKAPD
WQGYFYTVLLFVSACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTI
GEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMILMVPLN
AVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLK
KSAYLAAVGTFTWVCTPFLVALSTFAVYVTVDKNNILDAQKAFVSLALFNILRFPLNILP
MVISSIVQASVSLKRLRIFLSHEELEPDSIERRPIKDGVCIGSLCATEAPLGFGCEAPGS
RSSAEPGRGANSISVKNATFTWARSEPPTLSGITFSIPEGSLVAVVGQVGCGKSSLLSAL
LAEMDKVEGHVAVKGSVAYVPQQAWIQNDSLRENILFGRQLQERYYNAVIEACALLPDLE
ILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCDSDIYLFDDPLSAVDAHVGKHIFENVI
GPKGMLRNKTRLLVTHSISYLPQVDVILVMTGGKISEMGSYQELLARDGAFAEFLRTYAS
GEQEQAEHDDGLTSVSSPGKEVKQMENGMLVTDVAGKQLKRQLSNSSSYSGDVGRHHTST
AELQKAGAKNEDAWKLVEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFLCNNVAALA
SNYWLSLWTDDPIVNGTQEHTKVRLSVYGALGISQGISVFGYSMAVSIGGIFASRRLHVD
LLQNVLRSPMSFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFSVIGACIIILLA
TPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSIIRAFEEQ
ERFIRQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVG
LSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWRVEEMTPPSDWPQVG
RVEFRDYGLRYRENLDLVLKNINITIDGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEI
IVDNINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSRYSDEEVWTSLELAHLKDF
VSGLPDKLNHECAEGGENLSSGLGSGFGMVLTLCLLVFLCWSSVGQRQLVCLARALLRKT
KILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIREC
GQPSALLQQRGLFYSMAKDAGLV |
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| NT seq |
4752 nt +upstreamnt +downstreamnt
atggcgctccgcggcttctgcagcgctgatggctccgaccccttctgggcgtgggatgtc
acgtggaacaccagcaatcccgacttcaccaagtgctttcagaacacgttcctcgtatgg
gtgccttgttcttacctctgggtctgcttccccttctacttcctctatctctcacgccat
gaccggggctacattcagatgacctatctcaacaaaaccaaaactgccttgggatttttg
ctgtggatcgtctgctgggcagacctcttctactctttctgggaaagaagttggggcaaa
ttcctggccccggtgtttctggtcagcccaaccctcttgggcatcactatgctgcttgct
acctttttaattcaactcgagagaaggaagggagtccagtcctcggggatcatgctcact
ttctggcttgtagccctactgtgtgcccttgccatcttgagatccaaaatcatgactgcc
ttaaaagaggatgctgaaatcgacgtgtttcgcgatgtcactttctacatttacttttcc
ctcgtgctgatgcagctcgtgctgtcctgcttctcggaccgaccgcccctgttctctgaa
accatccacgaccccaatccctgcccggaatccagcgcctccttcctttccagagtcacc
ttctggtggatcacagggctgatggtccggggctaccgccagcccctggagagcactgac
ctctggtccctgaataaggaggacacgtcagaacaagttgtgcccgtcttggtaaagaac
tggaagaaggagtgtgccaaatccaaaaggcagcaggcgaagatggcgtactcctccaag
gatcccgccaagcccaaagggggctcgcaggtggatgtgaatgaggaggctgaggttttg
attgtcaagtccccccagaaggagcgggagccatctctcttcaaggtgttatacaagacc
tttggaccctacttcctcatgagcttcttattcaaggccctccatgacctgatgatgttt
gctggcccagagatcttaaagttgctcatcaacttcgtgaacgatcagaaggccccggac
tggcagggctacttctacaccgtgctgctgttcgtcagcgcctgcctccagaccctcgtg
ctgcaccagtacttccacatctgcttcgttagcggcatgaggatcaagacggccgtcatt
ggggccgtctaccggaaggctttggtgatcaccaactcagccagaaaatcctccaccatc
ggggagattgtcaacctcatgtctgtggacgcccagagattcatggacctggccacgtac
attaacatgatctggtcggctcctctgcaagtcatccttgctctctacctcctgtggctg
aacctgggcccgtccgtcctggctggggtggctgtgatgatcctcatggttcccctcaat
gccgtgatggccatgaagaccaagacctaccaggtggcccacatgaagagcaaagacaat
cggatcaagctgatgaatgagattctcaacgggatcaaagtactcaagctttatgcctgg
gagctggccttcaaagacaaggtgctggccatcaggcaggaggagctgaaggtgctcaag
aagtcggcctacctggcggctgtgggaaccttcacctgggtctgcacacctttcctggtg
gccctgtctacatttgccgtctacgtgaccgttgacaagaacaacatcctggacgcccag
aaagctttcgtgtctttggccttgtttaacatcctccgatttcccctgaatattctgccc
atggtcatcagcagcatcgtgcaggcgagtgtctccctcaaacgcctcaggatctttctg
tctcacgaggagctggagcctgacagcattgagcgaaggcccatcaaagacggtgtgtgc
attgggtccctctgtgccacggaggctcccctcgggtttggctgtgaggccccagggagc
aggagctctgcagagccgggcaggggcgcaaacagcatctctgtgaagaatgccacgttc
acgtgggccaggagcgaacctccgacgctaagtggcatcaccttctccattccggaaggt
tccttggtggccgtggtgggccaggtgggctgtggaaagtcgtctctgctctcagcactc
ctggccgagatggacaaggtggaggggcacgtggctgtcaagggctcagtggcctacgtc
ccccagcaggcctggattcagaatgattctctccgagaaaacatccttttcggccgccag
ctgcaggaacggtattataatgctgtcattgaagcctgtgccctcctcccagatctagaa
atcctgcccagtggggaccggacagagatcggtgagaagggtgtgaacctgtctgggggc
cagaagcagcgcgtgagcctggcccgggccgtgtactgtgactccgacatctacctcttc
gacgaccccctgtcggccgtggatgcccatgtgggaaaacacatatttgaaaacgtgatt
ggccccaaggggatgctgaggaacaagactcggctgctggtcacacacagcatcagctac
ctgccccaggtggatgtcatcctcgtcatgaccggtggcaagatctccgagatgggctcc
taccaggaactgctggcccgggacggcgccttcgccgagttcctgcgcacatatgccagc
ggcgagcaggagcaggccgagcacgatgatgggttaacaagtgtcagcagtccagggaag
gaggtgaagcagatggagaatggcatgctggtgacggatgtcgcggggaagcagctgaag
agacagctcagcaactcctcctcctacagcggagacgttggccgccaccacaccagcacg
gctgagctgcagaaagcgggggccaagaatgaggacgcgtggaagctggtggaggcagac
aaggctcagacggggcaggtcaagctgtccgtgtactgggactacatgaaggcaatcgga
cttttcatctcctttctgagcatcttccttttcctgtgtaacaacgttgcggctctggcc
tctaactactggctcagcctctggacagatgaccccatcgtcaatgggacccaggagcac
actaaagtccggctgagtgtctatggagccctgggcatttcgcaaggtatctcggtgttc
ggctactccatggcggtgtccattggggggatcttcgcttcccgccgcctgcacgtggac
ctgctacagaacgtcctccggtcgcccatgagcttcttcgagcggacccccagcgggaac
ctggtgaaccgcttctccaaggagctggacacggtggactccatgatcccgcaggtcatc
aagatgttcatgggctccctgttcagcgtcattggcgcctgcatcatcatcctgctggcc
acccccatcgctgccatcatcatcccgccgctgggcctcatctacttcttcgtccagagg
ttctacgtggcctcgtcgcggcagctgaagcgcctcgagtcggtgagccgctccccggtg
tactcgcacttcaacgagaccctgctgggcgtcagcatcatccgcgccttcgaggagcag
gagcgcttcatccgccagagtgacctgaaggtggacgagaaccagaaggcctattacccc
agcatcgtggccaacaggtggctggctgtgcggctggagtgtgtaggaaactgcatcgtc
ctgttcgctgccctattcgccgtgatctccaggcacagtctcagcgccggcttggtgggc
ctgtccgtgtcatactcactgcaggtgaccacgtacttgaactggctggttcgcatgtcg
tccgagatggagaccaacattgtggcggtggagaggctgaaggagtattcagaaacagag
aaagaggctccctggcgagtggaggagatgactccgcccagtgactggcctcaggtgggc
cgagtggaattccgagactacggcctgcgttaccgagaaaacctggacttggttctcaaa
aacatcaacatcaccatagatggaggggaaaaggttggcatcgtggggcggacgggagct
gggaagtcgtccctgaccctgggcttgttccggatcaatgagtctgctgagggggagatc
attgttgacaacatcaacattgccaagattggcctacatgatctgcgcttcaagatcacc
atcatcccgcaggaccctgttttgttctcgggttccctccgcatgaacctggacccgttc
agccggtactcagatgaggaagtctggacgtccctggagctggctcacctgaaggacttt
gtgtccggccttcccgacaagctgaaccacgagtgtgcagaaggcggggagaacctgagc
tccggcctgggctcagggttcgggatggttttgaccctgtgtctcctggtctttctgtgc
tggtcaagtgttgggcagcgccagcttgtgtgcctggcccgggctctgctgaggaagacc
aagatccttgtgttggacgaggccacggcagccgtggacctcgagacggacgacctcatt
cagtctaccatccggacgcagtttgaagactgcaccgtgctcaccattgcacaccggctc
aataccatcatggactacacaagggtcatcgtcctagacaagggagagatccgggagtgc
ggccagccctccgccctcctgcagcagaggggtcttttctacagcatggccaaagacgct
ggcctggtgtga |
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