Ursus maritimus (polar bear): 103670250 Help Entry 103670250         CDS       T03271                                  Symbol TSC1 Name (RefSeq) hamartin   KO K07206   tuberous sclerosis 1 Organism umr  Ursus maritimus (polar bear) Pathway umr04072   Phospholipase D signaling pathway umr04140   Autophagy - animal umr04150   mTOR signaling pathway umr04151   PI3K-Akt signaling pathway umr04152   AMPK signaling pathway umr04211   Longevity regulating pathway umr04218   Cellular senescence umr04714   Thermogenesis umr04910   Insulin signaling pathway umr05163   Human cytomegalovirus infection umr05165   Human papillomavirus infection umr05168   Herpes simplex virus 1 infection umr05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     103670250 (TSC1)    04151 PI3K-Akt signaling pathway     103670250 (TSC1)    04152 AMPK signaling pathway     103670250 (TSC1)    04150 mTOR signaling pathway     103670250 (TSC1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     103670250 (TSC1)   09143 Cell growth and death    04218 Cellular senescence     103670250 (TSC1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     103670250 (TSC1)   09149 Aging    04211 Longevity regulating pathway     103670250 (TSC1)   09159 Environmental adaptation    04714 Thermogenesis     103670250 (TSC1)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     103670250 (TSC1)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     103670250 (TSC1)    05163 Human cytomegalovirus infection     103670250 (TSC1)    05165 Human papillomavirus infection     103670250 (TSC1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hamartin Motif Other DBs NCBI-GeneID:  103670250 NCBI-ProteinID:  XP_008696897 UniProt:  A0A384CQ12 LinkDB All DBs Position Unknown AA seq 1163 aa AA seqDB search MAQQANLGELLSMLDSPVLSVRDEVTAVFKENLSSDRGPMLVNTLVDYYLETKSQPVLHI LTTLQEPHDKHLLDKMNDCMGRAASRLPALSLLGHVIRLQPPWKHKLSQAPLLPSLLKCL KVDTDVIVLTTGVLVLITMLPMIPQSGKQHLHDFFDIFGRLSSWCLKKPGHVTEIYLVHL HASVYALFHRLYGMYPCNFVSFLRSHYSMKENLDTFEEVVRPMMEHVRIHPELVTGSKDH ELDPRRWKRLETHDVVIECAKISLDPAEASYEDGDSVSPQVSARFPHRAADVAASPYVDM QNSCGSATSTPYSSSRLTLFSTPGQPPQTLSPPSTRLLTEPPQATLWSPSMVCGMTTPPT SPGNVPPDLSHPYSKVFGTTGGKGTPLGTPATSPPPAPLCHSDDYVHISLRQATATPPKK EEKTDSVRPCLHRQHHLPNDRGLEELPGSKGSVPLSDLPGFLGDLASEEDSIEKAKEEAA ISKELSEITTAGTEPLVPRGGFDSPFYRDSLPGCPRKNHSAASGAQGASVNPEPLNSSLD KLGPDTPKQAFTPIDPPCGGANQSPAGSRERQTALETDILTPSPCKIPPQRGVGFGSGQP PPYDHLFEVALPKTAHHFVSKKTKELLKKAKGNAEEDCPPSTSPAEVLDRLIQQGADAHS KELNKLSLPSKSVDWTHFGGSPPSDEIRTLRNQLLLLHNQLLYERFKRQQHALRNRRLLR RVIRAAALEEHNAAMKDQLKLQEKDIQIWKVSMQKEQARYSQLQEQRDTMVTQLHSQIRQ LQHDREEFYNQSQELQTKLEDCRNMIAELRLELKKANSKVCHTELLLSQVSQKLSNSESV QQQMEFLNRQLLVLGEVNELYLEQLQSKHSDTTKEVEMMKAACRKELEKNRSHVLQQNQR LDTSQKRILELESHLAKKDHLLLEQKKYLEDVKVQARGQLQAAESRYEAQKRITQVFELE ILDLYGRLEKDGLLKKLEEEKAEAAEAAEERLASCKDGCSDSVTGHNEEASGHNGETKPP RPGGGVRGGGASRGGGGGSELSTPEKPPTQRAGLFSSRWETTVGESATSIPTTVGSFPSS KSFLGMKARELFRNKSESQCDEDSVTISSLSETLKTELGKDPGAEAKTPLHLDGPQPSPP SPDSVGQLHIMDYDETHQEHSEG NT seq 3492 nt NT seq  +upstreamnt  +downstreamnt atggcccagcaagcaaacctcggggagctcctgtccatgctggactcccctgtgctgagt gtgcgcgacgaggtgacagctgtctttaaagagaacctcagctctgaccgtggtccgatg ctcgtaaacaccctggtggattattacctggaaaccaagtctcagccggtattgcacatc ctgactaccttgcaagagccgcacgacaagcacctcttggacaaaatgaatgactgtatg ggcagagccgcctctcggctgcccgcgctgtcgctgctggggcacgtcatcaggctgcag ccgccttggaagcacaaactctctcaagcacctcttttgccttctttactcaaatgtctc aaggtggacaccgatgtcatcgtcctcacgacaggtgtcttagtgttgataaccatgcta ccaatgattccacagtcggggaagcagcaccttcatgatttctttgatatttttggccgt ctttcatcgtggtgcctgaagaaaccaggccacgtgacagaaatctatcttgtccatctc catgccagtgtttatgctctctttcatcgcctctacggaatgtacccttgcaactttgtc tcctttctacgctctcactacagtatgaaggagaacttggacactttcgaagaagtggtc aggccaatgatggagcacgtgcggattcacccggaattagtgactggatccaaagaccac gaactggacccgcgaaggtggaagcgattagaaacacatgatgttgtcatagagtgtgcc aaaatctctctggaccccgccgaagcctcgtacgaagatggcgactccgtgtccccgcag gtgtcagcgcgctttcctcatcgtgcggctgatgtggccgccagcccttacgtcgacatg cagaatagctgtgggagtgctacctcgaccccttattccagctctcggctgacattgttc agtacacccgggcagccacctcagactctgagtcccccatcgacacggctgttgactgag ccgccacaagctactctttggagcccgtctatggtttgtggtatgaccactccgccaact tctcctggaaatgtcccacctgatctgtcacacccttacagtaaagtctttggtacaact ggtgggaaaggaactcctctgggaaccccagcaacgtctcctcctcccgccccgctctgc cactcagacgactacgtgcacatttccctccggcaggccacagccacaccccccaagaag gaagagaaaacagattcagtaaggccctgtctacacagacagcaccatctcccgaacgac agaggattagaagagttacctggcagcaaaggttctgtccctctgagtgaccttccaggg tttttaggggacctggcctccgaagaagatagcattgagaaagctaaagaagaagcggcg atatctaaagaactctccgagatcacgacagccggcaccgagcccctggttcctcgagga ggctttgactcccccttctaccgggacagtctcccgggctgccctcgcaagaaccattcg gccgcctctggtgctcagggcgccagtgtgaaccctgagcctttaaactcctccctggac aagcttgggcctgacacaccgaagcaagcctttactcccatagacccgccctgtggaggc gccaaccagagccctgccgggagcagggagcgccagactgcgctggagaccgacatcctc actcccagcccttgtaaaattccgcctcagaggggagtggggtttggaagtgggcagcct cccccttacgatcatctttttgaggtggcattgccaaagaccgcccatcattttgtcagc aagaagaccaaggaactgttaaagaaagcaaaaggaaacgcagaggaagactgtcctccc tcgacctcccccgcggaagtcctggacagactcatccagcagggagcagacgcgcacagc aaggagctgaacaagttgtccttacccagcaagtctgtcgactggacccactttggaggc tctcctccctcagatgagatccgcaccctccgtaaccagttgcttttactgcacaaccag ttgctctatgagcgttttaagaggcagcagcacgcgctccggaacaggcggcttctccgc agggtgatcagggcggcggccctggaggagcacaacgcggccatgaaagaccagttgaag ttacaagagaaggacatccagatctggaaggttagcatgcagaaggagcaggcccggtac agccagttgcaggagcagcgagacaccatggtcacccagctccacagccagatccgccag ctgcagcacgaccgggaggagttctacaaccagagccaggagctgcagacaaagctagag gactgcaggaacatgatcgcagagctgcgtctggaattgaagaaggccaacagcaaggtg tgtcacaccgagctgctgctcagtcaggtgtcccagaagctctcaaacagtgagtcggtc cagcagcagatggagttcttgaaccggcagctcttggtccttggggaggtcaacgagttg tatctggaacaactgcagagcaagcactcagacaccacaaaggaggtagagatgatgaaa gctgcgtgtcggaaagaactagaaaaaaacagaagccacgttctgcagcagaatcagagg ctcgatacctcccagaaacggattttggaactggaatctcacctggccaagaaagaccac cttcttttggagcagaagaaatatttagaggatgtcaaagtccaggcaagaggacagctg caggcggcagagagcaggtatgaggctcagaaaaggatcacccaagtgtttgaattggag atcttagatttatacggcaggttggagaaggatggcctcctgaagaaacttgaagaagaa aaagcagaagcggccgaagcggcagaagaaaggcttgcctcttgcaaggacggctgctcg gattctgtaacagggcacaacgaagaggcatctggccacaatggcgagaccaagcccccc cgacccggcggtggcgtgcggggtggcggtgcgagtagagggggtggcggcggcagcgag ctttcgaccccggagaaaccccccacccagagggcaggcctgttcagcagtcggtgggaa actaccgtgggagagtccgccaccagcatccccacgactgtcggctcctttcccagttca aaaagcttcctaggcatgaaggcgcgagagttatttcgtaataagagcgagagccagtgt gacgaggacagtgtgaccatcagtagcctttctgagacgctaaagacagaactgggcaaa gacccgggtgcggaagccaagacccccctgcacctcgacggcccgcagccctcccccccg agcccggacagtgttggacagctgcacatcatggactacgacgagactcatcaggagcac agcgaagggtga

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