KEGG   Ursus maritimus (polar bear): 103670772
Entry
103670772         CDS       T03271                                 
Symbol
AKR1A1
Name
(RefSeq) aldo-keto reductase family 1 member A1 isoform X1
  KO
K00002  alcohol dehydrogenase (NADP+) [EC:1.1.1.2]
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr00010  Glycolysis / Gluconeogenesis
umr00040  Pentose and glucuronate interconversions
umr00053  Ascorbate and aldarate metabolism
umr00561  Glycerolipid metabolism
umr00620  Pyruvate metabolism
umr01100  Metabolic pathways
umr01240  Biosynthesis of cofactors
umr05208  Chemical carcinogenesis - reactive oxygen species
Module
umr_M00014  Glucuronate pathway (uronate pathway)
umr_M00129  Ascorbate biosynthesis, animals, glucose-1P => ascorbate
Brite
KEGG Orthology (KO) [BR:umr00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    103670772 (AKR1A1)
   00040 Pentose and glucuronate interconversions
    103670772 (AKR1A1)
   00053 Ascorbate and aldarate metabolism
    103670772 (AKR1A1)
   00620 Pyruvate metabolism
    103670772 (AKR1A1)
  09103 Lipid metabolism
   00561 Glycerolipid metabolism
    103670772 (AKR1A1)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    103670772 (AKR1A1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:umr04147]
    103670772 (AKR1A1)
Enzymes [BR:umr01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.2  alcohol dehydrogenase (NADP+)
     103670772 (AKR1A1)
Exosome [BR:umr04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   103670772 (AKR1A1)
SSDB
Motif
Pfam: Aldo_ket_red
Other DBs
NCBI-GeneID: 103670772
NCBI-ProteinID: XP_008697503
UniProt: A0A384CRS9
LinkDB
Position
Unknown
AA seq 325 aa
MAASCVVLHTGQKMPLIGLGTWKSDPGQVKAAVKYALSVGYRHIDCAAIYGNETEIGEAL
KENVGPGKVVPREELFVTSKLWNTKHHPEDVEPALRKTLAELQLEYLDLYLMHWPYAFER
GDNPFPKNADGTIRYDSTHYKETWKALEALVAKGLVRALGLSNFSSRQIDDVLSVASVRP
AVLQVECHPYLAQKELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVILALAEK
YGRSPAQILLRWQVQRKVICIPKSITPSRILQNIQVFDFTFSPDEMKQLDALNKNWRYIV
PMLTVDGKRVPRDAGHPLYPFNDPY
NT seq 978 nt   +upstreamnt  +downstreamnt
atggcggcttcatgtgtcgtcctgcacactgggcagaagatgcccctgattgggctgggc
acctggaagagcgatcctggccaggtgaaagcagctgttaagtacgccctgagtgtaggc
taccgccacattgactgtgctgctatctatggcaatgagactgagattggggaggccctg
aaggagaatgtgggacctggcaaggtggtgcctcgagaggagctgtttgtgacttctaag
ctgtggaacactaaacaccaccctgaggatgtggagcctgccctccggaagacgctggct
gagctccagttggagtatttggacctgtacctgatgcactggccctatgcctttgagcgg
ggagacaaccctttccctaagaatgccgatgggactatccgctatgactctacccactac
aaggagacctggaaagcgctggaagcactggtggcgaaggggctggtacgggcactgggc
ctgtccaacttcagcagtcggcagatcgatgatgtgctcagtgtggcctcggtgcgccca
gctgtcctgcaggtggaatgtcacccatacttggctcagaaggagctgattgcccactgc
caagcacgcggcctggaggtgacggcttatagccctcttggctcctctgatcgagcttgg
cgtgatcctgatgaaccggtcctacttgaggagccagtgatcctggcactggctgaaaag
tatggccggtctccagctcagatcctgctcaggtggcaggtccagcggaaagtgatctgc
atccccaagagtatcaccccttcacgtatcctccagaacatccaggtgtttgactttact
tttagcccggacgagatgaagcagctagatgccctgaataaaaattggcgatacattgtg
cccatgctcacagtggatgggaagagagtcccgagagatgcagggcaccctctgtacccc
tttaatgacccatactga

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