Ursus maritimus (polar bear): 103671941 Help Entry 103671941         CDS       T03271                                  Symbol APOB Name (RefSeq) apolipoprotein B-100   KO K14462   apolipoprotein B Organism umr  Ursus maritimus (polar bear) Pathway umr04975   Fat digestion and absorption umr04977   Vitamin digestion and absorption umr04979   Cholesterol metabolism umr05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:umr00001]  09150 Organismal Systems   09154 Digestive system    04975 Fat digestion and absorption     103671941 (APOB)    04979 Cholesterol metabolism     103671941 (APOB)    04977 Vitamin digestion and absorption     103671941 (APOB)  09160 Human Diseases   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     103671941 (APOB)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:umr04147]     103671941 (APOB)    00536 Glycosaminoglycan binding proteins [BR:umr00536]     103671941 (APOB) Exosome [BR:umr04147]  Exosomal proteins   Exosomal proteins of other cancer cells    103671941 (APOB) Glycosaminoglycan binding proteins [BR:umr00536]  Heparan sulfate / Heparin   Others    103671941 (APOB) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Vitellogenin_N Vit_open_b-sht DUF1081 ApoB100_C Motif Other DBs NCBI-GeneID:  103671941 NCBI-ProteinID:  XP_040479656 UniProt:  A0A8M1F8I6 LinkDB All DBs Position Unknown AA seq 4441 aa AA seqDB search MGPPRPALLLLLLAVAGAWAQEEVPENVSPSCPKDGTRFKHLRKYIYNYEAESSTGVAGD SFSRSATRINCKVELEVPQLCSFILRTSQCTLKEGYSFNPNSRPSLHKSKNSEEFAAAMS KYELRLAIPEGKQVSLYPEKEEPKHILNIKRGIISALLVPPETEEAKQVLFLDTVYGNCS SDLTVETKEANVATGISIERDLENCDHFKPISTGVSPLALIKGMLHPFSTLISSNQSCQY TLDPKNKHVSEAICKEQHVLLPFSTKDKHAMMAQVTQTLKLEDTPKINSRFFDEGTEEVG LAFESTKSASAPKQAEAIVKTIQELQTLHVSEKNAQRANLFNKLVTELRSLNNEAFTSLL PKLVEVSSPITLQALIQCGQPQCYTHILQWLRSEKASPLLIDVVTYLAALMPEPSAERLR EIFSTAKEQQSRATLYALSHVVNNYHKANPVVTQDLLDIADYLLEQIRDDCTGNKDHTYL ILRVIGNIGRTMETVTPRLTSSILKCIKSTEPSLLIQKAAIQALRKMELKDEVREVLLQI FLSDASPGDKRLAAYLMLMRDPSQSDMKQIIQLLPREQNEQVKNFVASHIANILNSEELH IKNLKKLVEEALKGSQLPTILDFSKFSRNYHLSKSVSLPSLDPISAKIEGNLIFDPNNYL PKESMLKTTLNVFGFAPADLFEIGLEGKGFEPTLEALFGKQGFFPDSVNKALYWVDDQVP DHVSKVLVDHFGYTKDDKREQDMVNGIMLNVERLIKDLKSREFPEARAYLHILGEELGFV RLHDLQLLGKLLLNGVRTLPGIPQMIGEAIKKGSMSDLFLHYIFMDNTFELPTGIGLQLQ VSSSGVIAPGIGAGMKLHTANSQMELVTKPSVSVEFVTNMGIIIPDFSRTMFQMNTNLFH ETGLEMHVVFKAGQLKFIIPSPTMPVKLFSGRNTVHFISTTNTEEAPSLKENTEGWSDCK PLFTGLDFCTSSSHYTTTTSPEPASFYPLSQDTRLELELKPTGEVELYSASVTYELQKEA GALVDTLTFVTQTEGAKQTEATMMFKYNRQSMTLSSEIQIPDFDVDLGTILRVSDESAME KKSYKLTLDLQNKRITEVTLTGHISYDRREKGKIKGVISIPRLQAEARSEILTQWSPTKL LLLMDSSATAYGSTISKKLVWRYDEEKIEFEWNTGTNVDTKKAASNFPMDFSDYPKSLHV YANSLLDHPVPQTDMTFRHMGSKLIVATNTWLQKASSSLPYAQNLQDHLSGLKELYLQKM GLPDLHIPENLFLKSDGRIKYTLNKNSVKIEIPLPFGGKSSKDLKMLETIRTPDLNFKSV GFHLPSREFQVPTFTIPELYQLRVPLLGVLDLSTNIYSNLYNWSASYTGGNTSTNHLSLR AWYHMKADSVVDLLSYSVQGSGETTYDHENTFTLSCDGYLHHKLLDSNMKFSHVEKIRNN PASKSLLTFNASSAWGPQMSASVHLDAKKKHHLYVKEAKIDGQFRVSSFYAEGTYDLSYQ RDSTTDQLSGESNLRFNSSYLQGTNQITGRYEDGALSLTSTSDLQDGIIKNTAFLRYENY ELILKSDTNGKHEDFAASNKVDMSFSKQNALLRSEYQADYKSLRFFTLLSGSLNSHGLEL NADILGTDKINSGAHKATLRIAQDGMSTSATTNLKYSPLVLENELNTVLGLSGASMRLTA NGRFREHNAKFSLDGKAALTEVSLGSAYQAMILGVDSKNVFNFKISQEGLKLSHDMMGSY AEMKLDYENNLNIAGLSLDFSSKLDNIYSSDKFYKQNVNVQLQPYSLVTTLKNDLKFNAL DLTNSGKLQLEPLKVNVGGNIKGVYQNNEIKHIYTISYADLSASYKTDTVAKVQGTEFSH RLNTNIAGLASAIDISTNYNSDSLHFSNVVHSAMAPFTMTIDGHTNGNGKLSLWGEHTGQ LYSKFLLKAEPLALTFSHDYKGSTSHHLPLKSTISTGLDHKVSALLTPAEQTGTWKLKTQ LNQNEYIQDFDAYNDKDRVGVELRGQALADLTMLDFSIQVPFLLNEHTNIIDALGMRDAV GQPQEFSVVASVKYDKNQDVHTINLPFFEILPEYFEEKRMVIITALETIQRELKLIDVDQ FVSKYRTALDKLPQQVDGYLNALNWERQVLNAKEKLTALTENYRITENDLQIALDNTKIS LNDTLSQLKTYVIQFDQYINDNYDLHDFKTAIAKIIDQIIEKLKILDEHYHINVNLVKTI HDVCLFIEKTDFNRIGNSTALWIQNVDAKYKIKIQIQEKLQQLKTQIQNIDIQHLAEQLK QQVEAVDVRDLLHWLRITIPFQRIKEIIEHVKYYVINLMDGFKVAEKINALGASSHQLIK MYEIDQYIQVLMDKSVQLAHQYKLKETVQKLSSVLQQVKIKDHFEKLVTFIDNAIQQLKA LSFKKIIEQVNRFLDMLTNRLRSFDYHQFVEETNNKIREVTQRLNGEIQALELSQKAKAL ALFVEDIKATVLVHLEHLKGTQINLFFDWLQEALSSTSLTYMKEKFREILEDIRDRVYQM DIQQEVQWYLSLVGQVYSTLVTYISDWWSLAAKNLTDFAEQYSIEDWAENLKALVEQGFT VPEIQTTFGTMPAFEVSLRALQEATFQTPDFIVPLTDLKVPSIQINFKRLKDIEMPSKFA TPEFTVLNTFHVPSFTIDLVEIKVKIIRTIDQMLHGELQWPVPEVDLRDLMGVDTILASI TLPDFHLPEITIPEFIIPNLDFKDYQVPDLHIPEFQLPHMSHTLDVPTFGKLHSILKIQS PLFTLDANADIQNVTTSGNRAEITASLTAKGESKLEVLNFDFQANAQLSDPEINPLVMKQ SMMLSSKYLKTEHKSEVLFVGNTIEGKSNTVAGLHTEKNTVELSHGALVRINNQLTLDSN AKYFHKLNIPKLDFSSQAELRNEIKTLLEAGHIAWNSSGIGSWKWACHTFSDEGAHESQA SFTMERPITSFGWSNKINSKHLRLIQNLVYESGFLDFSKFEIQSQVESQHVGRSVLAVKG TAKLGERKAEITGNHDAHLNGKVIGTLKNSLFFTAQPFEITASTNNEGNLKVSFPLKLIG KVDFLNNYALFLSPSAQQASWQASARFNQYKYHQNFSAGNNENSAEAHIGINGEANLDFL NIPLTIPEMTLPYTTFTTPQVKDFSLWEKTGLKDFLKTTKQSFDLSVKAQYKKNKDKHII PIPFYTKDFQVLSTPNDIFIPAMGNITYDFSFKSGIITLNTIVGLYNQSDIVAHFLTSSS SATDALQYKLEGTSSLTRKRDLKLATALSLSNKFVEGNHDSTISLTKKNMEASVTTSAKV QIPILRMNFKQELNGNTKSKPTVSASIELTYDLNSPERYSTATGTVSHKFNLESLTSYFS IESSTKGDIKGSVFSREYSGTIASEASTYLNSKSTRSSVKLQGASKVDDIWNLEVKENFA GEATLQRIYGIWEHNTKNNLQLEGFFSSSGEHTSKATLELSPWKMSALIQVHASQPSSLL EINYLGQEVSLKANAENQKVSWKSEVQVHSEFFQNNIQLSNDQEEARLDIASSLKVSLGF LKDTVLPVYDKSLWDLLKLDVTTSIDRKQYLNASTAFVYTKNPNGYHFSVPVQELADKFI IPRLKLNDLNSSFVIPTFQVPFTDLQVPSYTFDFSEIKIYKKLNTLPFVLNIPTLPQVKF PKVDVLTKYSEPEDSSVPFFEITVPASQLTVSQLTVPKSISADSAVGYLNEVASKIADFE LPAITIPEQTIEIPSIKFSVPAGIFIPSFGALTAHFGVASPLYNATWSAGLKNKVEYFGT FLNSTCSSTIQFLEYDLNVVGTHKIEDGMLVCRTKGTFAHRDISAEYKEDSKYRGLQDWK KEIRLDITSPTFTDVHLYHQLSENSLSSSVASPAIGTVALDLEDNNSTLKWNLYYRPQSS LDKKLNLFKTEWKYEEPGEKHQIKVSWEEEAATELLSTLKDNVPKATRVLYDYANKYHQE HTGLNLRDASLKLRGSLQNSAEWAYQGAMRQIDEVDIGFQRVARVTTRTYQQWKDKAQDL YQKLLLAQGDQADFQGLWNEMFNRVIGVTQEYNIIVSRQIDSLIDFLKFTRFQLPGKAGT YTKDEVCSVVMREVGQVLFQVYSKIHSGLEILFSYFQDLMEKSELTKDLEIKIPFDSKRF KLIDVISESGTMLEHFSEKLQDIFNNLRSRNTTEMLRDLQSYLQRTSQEIENDIQVLKRI KFRSLIDHIQYNANGIFNESIPYVLAPVELMFGKFNRFVEKQLHEASQQLQKRHQIIKDL HKEYVDPSVVSWTGRFYELEEKIISSLKNLMDVLNDVHASYTVGSIYLVSHISDQVQQFV QKDIQEYLSILTDADGKGKEKIAELSTSAQEIIKSWAIAMKEIISDYRQQFTYKLQDFSD QLSDYYEKFITESKRLIDLSTQKYHMFLRYIIELLKELQSAAVNNMIPYIKVSPGEFTIT L NT seq 13326 nt NT seq  +upstreamnt  +downstreamnt atgggccctccgaggcccgcgctgctgctactgctactggcggtcgcgggcgcctgggcg caagaggaggtgccggaaaatgtcagccccagctgcccaaaagatggaactcgcttcaaa cacctcaggaaatacatatacaactatgaggctgagagttccactggtgttgctggggat tctttctcaagaagcgccaccaggatcaactgcaaggttgagctggaggtcccccaactc tgtagcttcatcctcaggacaagccagtgcacgctgaaggaggggtatagcttcaacccc aacagcaggccctcactgcacaagagcaagaactctgaggagtttgctgctgccatgtcc aagtacgagctcaggctggccattcctgaagggaagcaggtttcactttacccagagaag gaagagcctaaacatatcctgaacatcaagagaggtatcatttctgccctcctggttccc ccggagacagaagaggctaaacaagtgttgtttctggatactgtgtatggaaattgttcc agtgacttaactgttgaaacaaaggaggcaaatgtggcaacaggaatatccattgaaagg gacctggagaactgtgatcacttcaagcccattagcacaggagttagcccacttgctttg atcaaaggcatgctccaccccttttcaactctgattagcagtaaccagtcctgccagtac actctggaccccaagaataagcatgtgtcagaagccatctgcaaggaacaacacgtgctc ctgcctttctccaccaaggataagcatgcgatgatggcacaagttacacagactttgaaa cttgaagacacacctaagatcaacagccgcttctttgatgaaggtaccgaggaggtgggt ctcgcctttgagagcaccaaatccgcatcagctccaaagcaggccgaggccatcgtgaag actatccaggagcttcaaacattacatgtctctgagaagaatgcccagagagctaacctc ttcaataagctggtcactgagctgaggagtctcaacaatgaggcattcacatccctcttg ccaaagctggtcgaggtgtccagccccatcaccttgcaagccttgattcagtgtggacag ccccagtgttacactcacatcctgcagtggctgagaagtgagaaggccagtcccctcctg atagatgttgtgacgtacctggcggccctgatgccagagccctcagctgagaggctgcga gagatcttcagcacagcaaaggagcagcagagccgggccactttatatgctctgagtcac gtggtcaacaactatcataaggcaaaccctgtggtgacccaggacctgttggatattgct gattacctgttggaacagattcgtgatgactgcactgggaacaaagatcacacctacttg attctgagggtcattgggaatattggcagaaccatggagacagtaaccccaagactcaca tcttcaatcctgaaatgtatcaaaagtacagagccatccctactgattcagaaggctgcc atccaggccctgcggaaaatggaacttaaagatgaggtccgggaagtccttcttcagatt ttcctcagtgatgcctctccaggggataagcgactggctgcctatctcatgctgatgagg gacccttcccagtcagatatgaaacaaatcatccagcttctcccacgggaacagaatgag caagtgaagaactttgtggcttcccacatcgccaacatcttaaactcagaagaattgcat atcaaaaacttgaaaaagttagtggaagaagctctgaaaggatctcaactcccaaccatc ctggacttctcaaaattttcccggaactatcacctttccaaatctgtttcccttccatcg cttgaccccatctcagccaaaatcgagggaaatcttatatttgatccaaataattacctt cctaaagaaagcatgctgaaaacaaccctcaatgtctttggatttgctccagcggacctc tttgagattggtttggaagggaaaggttttgagccaacattggaagctctttttggaaag caaggatttttcccagacagtgtcaacaaggctttgtactgggttgatgaccaagttcct gatcatgtctccaaggtcttggtcgaccacttcggctacaccaaagatgataaacgtgag caggatatggtcaatggaattatgctcaatgttgagaggctgatcaaagatttgaaatcc agagaattcccagaagccagagcctacctccacatcctgggagaggagcttggctttgtc aggctccatgacctccagctcctgggaaagctgctgctgaatggtgttcgcactcttccc ggtatcccccagatgattggagaggccatcaagaaaggctcaatgagtgacttgtttctt cactacatcttcatggacaacacctttgaactgcccactggaattgggttacaactgcaa gtctcctcctctggagtcatcgctcctggaatcggggccggaatgaagctgcacacagcc aattcgcagatggagctggtgaccaagccctctgtgtccgtggagtttgtgacaaacatg ggcatcatcatcccggacttttcaaggactatgttccagatgaacaccaacctcttccat gagacaggcctggagatgcacgttgtctttaaagctgggcagctgaagttcatcattcct tctccaacgatgccagtcaagctgttcagtggccgtaacacagtccatttcatctccacc acaaacacagaagaggctccatctctgaaagagaacacggagggctggtcggattgcaag cctctctttacgggcctggacttctgtacctcgagttctcactacaccaccaccacctcc ccagaacctgcctccttctatccgctgtcccaggacaccagacttgaactggaactgaag cccaccggagaagtagagctgtattctgcaagtgtaacctacgaactgcagaaagaggct ggagccttggtggacacactgacgtttgtaactcagacagaaggtgcaaagcagaccgag gctactatgatgttcaaatataaccggcagagtatgactttgtccagtgaaatccaaatt ccagattttgatgttgaccttgggacaatcctcagagttagtgatgaatctgctatggaa aaaaagtcttacaagctcactttggaccttcagaacaagagaatcactgaggtcactctc actggccacataagctatgacagaagggaaaaaggcaaaatcaaaggtgttatttccata ccccgtctgcaagcagaagccagaagtgaaatcctcacccagtggtctcccacaaaactc ctcctcctaatggactcatccgctacagcttatggctcgacaatctccaagaagctggta tggcgttatgatgaagagaagattgaatttgaatggaacacaggcaccaacgtggatacc aaaaaagcagcttctaatttccccatggatttctctgattatcctaaaagcttgcacgtg tatgccaatagtctcttggatcacccagttcctcaaacagacatgactttccggcacatg ggttccaaattaatagttgcaacaaacacatggcttcagaaggcatctagtagtcttcct tatgcccagaatttgcaagatcacctcagtggcctaaaagaattgtacctccagaaaatg ggattaccagacttgcacatcccagaaaacctcttcttgaaaagtgatggccggatcaaa tacacattgaacaagaacagtgtgaaaattgagattcctttgccttttggtggaaaatcc tccaaagatctaaagatgttagagactattcggacaccagacctcaacttcaagtccgta ggattccacctgccgtcccgggaattccaagtccccacttttaccattcccgagttgtac caactgcgagtgcctctgttgggtgttctagacctctctacaaatatttacagcaatttg tacaactggtccgcctcctacactggtggcaacaccagcaccaaccacttgagccttcgg gcttggtaccacatgaaggctgactctgtggttgacttgctgtcctacagtgtgcaagga tctggagaaacaacgtatgaccacgagaatacgttcacattatcatgtgatgggtatcta caccacaaattactggattcaaatatgaaattcagtcacgtggaaaaaattagaaataat ccagcctcaaaaagtttgctgacatttaatgcttctagtgcctggggacctcagatgtct gcttcagtacatttggacgcaaaaaagaaacatcatttgtatgtcaaggaagccaagatt gatgggcagtttagagtctcttcattctacgctgaaggcacatatgacctgtcttaccag agggattctaccactgaccaattaagtggagagtccaacctgaggtttaactcctcctac ctccagggtaccaaccagataacaggaagatatgaggatggagctctctccttaacctcc acctcggatctgcaagatggcatcattaaaaatactgctttcctgagatatgagaactat gagctgatcctgaaatcggacaccaatgggaagcatgaggactttgccgcttctaacaaa gtggatatgagcttctctaagcaaaatgcattgctacgttctgagtatcaggctgattac aagtcattgagattcttcaccctgctttctggatcactaaattcccatggccttgaatta aatgctgatattttgggcactgacaaaattaacagtggtgctcacaaagcaacactaagg attgcccaggatggaatgtctaccagtgcgactaccaacttgaagtatagccctctggtg ctggagaatgagctgaacacagtgcttggcctctcgggagcatctatgagattaacagcg aatggccgcttcagggaacacaatgcaaaattcagtctggatggaaaagctgccctcaca gaagtatcattgggaagtgcttatcaggccatgattttgggtgtcgacagcaaaaatgtc ttcaacttcaaaatcagtcaggagggcctgaagctttcacatgacatgatgggatcttat gctgagatgaaactcgactacgagaacaacctgaatattgcagggttatcactggacttc tcttcaaaacttgacaacatttacagttctgacaagttttataagcaaaatgttaatgta cagctacagccctattctcttgtaactactttaaaaaatgacctgaaattcaacgctctg gatctgaccaacagtgggaaattacagctagaacccctgaaggtgaatgtgggtggaaac ataaaaggagtctaccagaacaatgaaataaaacacatctacaccatttcttatgctgac ttatcagcaagttataaaacagacaccgtagctaaagtgcagggtacagagttcagccat cggctcaacacaaacatcgctgggctagcttcggccatcgacatcagtacaaactacaac tcggactcactccatttcagcaacgttgttcactctgccatggccccatttacaatgacc atcgatggacatacaaatggcaatgggaaactgagtctctggggagaacatactgggcag ctatatagcaaattcctgttgaaagcagaacctctggcccttactttctctcatgattac aaaggatccacaagccaccatctcccgttgaagagcaccatcagtaccggtcttgatcac aaagtcagtgccctgcttactccagctgagcagacaggcacctggaaactcaagacccag ctgaaccaaaatgagtacatccaggacttcgatgcttacaatgataaagacagagttggt gtggagcttagaggacaagccctggctgacctcaccatgctagacttctcgattcaagtg ccatttttactcaatgaacataccaacataattgatgctttagggatgagggatgctgtt ggccagccccaagaattcagtgttgttgcttctgtaaaatatgataagaatcaagatgtc cacaccatcaacctcccattctttgaaatcctgccagaatattttgaggagaaacgaatg gtaattataacggcactggaaaccatacagagagaattgaaactcatcgatgttgatcag tttgtgagtaaatacagaacagccttggacaagctcccacagcaagtcgatggttatctg aatgcactcaattgggagagacaagttttgaatgccaaggagaaactaactgctctcaca gagaactatagaattacagaaaatgatctacaaatcgcgttggacaataccaaaatcagc cttaatgacacactgtctcagctaaaaacatatgtgatacaatttgatcagtatattaat gataattatgatttacatgattttaaaacagctattgctaagattattgatcaaatcatt gaaaaactgaaaatccttgatgaacattatcatatcaatgtaaatctagtaaaaacaatc catgatgtgtgtttgtttattgaaaagactgactttaacagaattggaaatagtactgca ctttggattcaaaatgtggacgctaagtataaaatcaaaatccagatacaagagaaattg caacagctcaagacacagattcagaatatagacatccagcaccttgctgaacagttaaaa caacaggtcgaggctgttgatgtcagagatcttttacattggttgagaattacaattcca tttcaaagaataaaggaaattattgagcatgtcaaatactatgttataaatcttatggac ggttttaaagtagctgagaaaatcaatgcgcttggagccagttcccatcagttaattaag atgtatgaaatagaccaatacatccaggttttaatggataagtcagtacagttggcccac caatataagttgaaggagactgttcagaagctaagcagtgtcctacaacaagttaagata aaagatcactttgagaaattggttacatttattgataatgctatccagcaacttaaagca ttgtcttttaaaaaaatcattgaacaagtaaacagattccttgatatgttgacaaataga ttaaggtcatttgattatcaccagtttgtagaggaaaccaataacaaaatccgtgaggtg acccagagactcaacggtgaaatccaggccctggaactttcacagaaagctaaagcactg gcactatttgtagaggacatcaaggccacggtcttagtccatctggaacacctaaagggc acccaaataaacctattcttcgattggttgcaggaagctttaagttcaacatctttaacc tacatgaaagaaaaattccgagagatcctagaagatatacgagaccgggtgtatcaaatg gacattcagcaggaagttcaatggtacctgtccctggtcggccaggtttacagcacgctt gtcacttacatttctgactggtggagtcttgctgctaagaacctcactgactttgcagaa cagtattctatcgaagactgggctgagaacctgaaagccttggtagaacaagggttcact gttcctgaaatccagaccaccttcggaaccatgcctgcctttgaagtcagtctccgtgct cttcaggaagctacatttcagactccagacttcatagtccccctgacagatctgaaggtt ccatccattcagatcaacttcaaaaggttgaaagatatagagatgccgtccaagtttgcc acaccagaatttactgtccttaataccttccatgtgccttcctttacaattgacctggta gaaataaaagtgaagatcatcagaaccattgaccaaatgctgcacggtgagctgcagtgg ccagttccggaagtggacctgagggacctgatgggggtggacaccattcttgctagcatc actctgccagacttccatttgccagaaatcacaattccagaattcataatcccaaatctc gattttaaagattaccaagttcctgaccttcacataccagaattccagcttccccacatg tcacacacacttgatgtccctacttttggcaagcttcatagcattttgaaaatccagtct ccccttttcacattagatgcaaatgctgacattcagaatgtaacaacttcagggaacagg gcagagatcacagcctccctcaccgccaaaggagagtccaaattagaagttctcaatttt gattttcaagccaacgcacagctttcagaccctgagattaatccactggttatgaagcaa tccatgatgttgtccagcaagtacctaaaaacagagcacaagagcgaagtgctgtttgtt ggaaatactattgaaggaaaatcaaacacagtggcaggtttacacacagaaaaaaatacg gtggagcttagtcatggtgcgctcgtcaggataaacaatcagcttactttggacagcaat gcaaagtacttccacaaattgaacattcccaaactggacttttccagccaggctgagctg cgtaatgaaatcaagaccctcttggaagctggacacatagcatggaattcttctggaata gggtcgtggaaatgggcctgccacacattctcagatgaaggagcacatgaatcacaagct agctttactatggagcgacccatcacttcctttggatggtctaataagatcaatagcaaa cacctaagattaatccaaaacttggtttatgaatctggcttcctcgacttttctaaattt gaaatccagtcacaggttgaatcccaacatgtggggcgcagtgttctagctgttaaaggc acagcaaagcttggagaaaggaaggcagagataactggcaaccatgatgctcatttaaat ggaaaagttattggaactttgaaaaattctcttttctttacagcacagccatttgagatt actgcatccacgaacaacgaagggaatttgaaagttagttttccactaaaattgataggg aaggtagatttcctgaataattacgcattgtttttgagtcctagtgcccagcaagcaagt tggcaagcaagtgccaggttcaaccagtataagtaccatcagaatttctctgctggaaac aatgagaacagcgctgaggcccacataggaataaatggagaagccaacctggatttcctc aatattcctttgacaattcctgaaatgactctaccttacacaacattcacaactccccag gtgaaagatttctccttgtgggaaaaaacaggcttgaaggatttcttgaagacaacaaag caatcatttgatttaagtgtaaaggctcagtataagaaaaacaaagacaagcatatcatc ccaattcctttttatacaaaagatttccaggtattgagtaccccaaatgatattttcatt ccagccatgggcaatattacctatgacttttcctttaagtcaggcatcatcacactgaat accattgttggactatataaccagtcagatattgttgctcatttcctaacttcctcttct tctgccaccgatgcactgcagtacaaattagagggcacctcaagtttgacaaggaaaaga gacttgaagctagccacagctttgtctctgagtaataaattcgtggaaggcaatcatgac agtactattagtttgaccaagaaaaacatggaggcatcagtgacaacatctgcaaaagtc caaattcccattttgagaatgaatttcaagcaagaacttaatggaaataccaagtcgaag cctactgtctctgcatccattgaattaacgtatgatctcaattcccctgaacggtactct actgctacagggacagtcagccacaaattcaacttggagagcctcacctcttacttttcc attgaatcatctaccaaaggagatatcaagggttcagtcttttcacgggaatattcagga actattgccagtgaggccagcacttacttgaattccaagagtactcggtcttcagtgaag ctgcaaggggcttccaaagttgatgatatttggaaccttgaagtaaaagaaaattttgct ggagaagccactctgcaacgcatctatggcatctgggaacacaacacgaaaaacaattta cagctagagggcttcttttcatcatctggagagcatacaagcaaagccaccctggaactc tccccatggaaaatgtcagccctcattcaggtccatgcaagtcagcccagttccctcctt gaaatcaattaccttggccaggaggtgtccctgaaagctaacgctgagaaccagaaggtc agctggaaaagtgaggtccaggttcattctgagttcttccagaacaacatacagctttcc aatgaccaagaagaggcacgccttgacattgcaagttccttaaaagtgtccctagggttc ctcaaagatactgtccttccagtttatgacaagagcttatgggacctcttaaagctggat gtcaccaccagcattgataggaaacagtatcttaatgcttcaactgcctttgtgtacacc aaaaaccccaacggctatcatttctctgtccctgtgcaagaactggctgataaattcatt attcctagactgaaactaaatgatctaaattcaagttttgtcatacctacattccaagtc ccatttacagatcttcaggttccatcctatacatttgattttagtgaaataaaaatctac aagaagctaaacactttgccatttgtcctcaatataccaacactaccccaagtgaaattc cccaaagttgatgtgttaacaaaatattctgaaccagaagactcctcggttccctttttt gagataactgtgcctgcgtctcagctaactgtgtctcagttaaccgttccaaaaagtatt tcagctgacagtgctgttgggtatctaaatgaggtggccagcaagattgcagactttgag ttgccagccattaccatacctgagcagactattgagattccttccattaagttctctgta cctgctggaattttcattccatcctttggagcactgactgcacattttggagtggcctct cccctatataatgctacttggagcgctggcttgaaaaacaaagtagagtacttcggaaca ttcctgaattccacgtgcagctcaaccattcagttcctggaatatgatctaaatgttgtg ggaacacacaaaatcgaagatggcatgttagtctgtaggacgaagggaacatttgcacac cgtgacatcagtgcagaatataaagaagatagcaaatatcgaggacttcaggactggaaa aaagagattcgccttgacatcaccagcccaacattcactgatgtccatctgtaccaccaa ctaagtgagaatagcctctcctcctctgtggcctccccagccataggcactgtagccttg gacttggaggacaataatagtaccttaaaatggaacctgtactatcgccctcagtcctct ctagataaaaaacttaacctattcaaaactgagtggaagtatgaggaacctggtgagaaa catcagatcaaagtcagctgggaagaggaggcagcaactgaactactaagcactctcaaa gacaatgtgcccaaggccacaagggttctttatgactatgctaacaagtaccaccaggag cacacaggactcaatctgagagatgcttctttaaaactgagaggaagtctgcagaacagc gctgagtgggcctatcagggtgccatgaggcagattgatgaggtggacatagggttccag agggtagccagagtcaccactagaacctaccagcagtggaaggacaaggcccaggatctg taccagaaactgttactggctcagggagaccaagctgatttccagggactctggaatgag atgtttaatagagtaataggagttactcaggaatacaatatcatagtcagtcgtcaaatt gactcattgattgatttcctgaagttcaccagattccaactcccaggaaaagctgggaca tacactaaagatgaagtctgcagtgtggtcatgagggaagtagggcaggtgctgttccag gtatattcaaaaatccatagcgggttagaaatactgttttcctatttccaagacctgatg gagaaatctgaattaaccaaggacctagaaattaaaattccttttgattcaaagagattt aaactaatagatgtaatctcagagtctgggacaatgttggaacatttttcggaaaagcta caggatatatttaataaccttcggtctcgcaatactacagagatgctaagggatcttcag agctatttacaaagaacttcccaagagatagaaaatgatattcaagtcctcaagaggata aaatttcgttctctcattgatcatattcaatacaatgccaacggaatcttcaatgaatct attccatatgttcttgcacccgtggaacttatgtttggcaagtttaatagatttgttgaa aaacaacttcatgaagcttctcaacagttacagaagcgccatcagatcataaaggatctt cacaaagaatatgttgatccaagtgtggtcagctggacagggaggttttatgaacttgaa gaaaagattatcagctcactcaagaacctaatggatgtccttaacgacgtgcacgccagt tacactgtcggtagtatttacttggtttcccacatctcagatcaagttcagcagtttgtg cagaaagatatccaggaataccttagcatccttactgatgcagatggaaaagggaaagaa aagattgcagagctttctaccagtgctcaggaaataattaaaagctgggccattgcaatg aaggaaatcatttctgattaccgccagcagttcacatataaactacaggatttttcagac caactctctgattactatgaaaaattcattactgagtccaaaagattgattgacctgtcc actcaaaaataccacatgtttctgagatatatcattgaattactgaaagagctacaatcg gccgcagtcaacaacatgattccctacatcaaggtttctccgggagaatttactatcacc ttgtaa

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