Ursus maritimus (polar bear): 103672740
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Entry
103672740 CDS
T03271
Symbol
KDR
Name
(RefSeq) vascular endothelial growth factor receptor 2 isoform X1
KO
K05098
kinase insert domain protein receptor [EC:
2.7.10.1
]
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr01521
EGFR tyrosine kinase inhibitor resistance
umr04010
MAPK signaling pathway
umr04014
Ras signaling pathway
umr04015
Rap1 signaling pathway
umr04020
Calcium signaling pathway
umr04151
PI3K-Akt signaling pathway
umr04370
VEGF signaling pathway
umr04510
Focal adhesion
umr05205
Proteoglycans in cancer
umr05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103672740 (KDR)
04014 Ras signaling pathway
103672740 (KDR)
04015 Rap1 signaling pathway
103672740 (KDR)
04370 VEGF signaling pathway
103672740 (KDR)
04020 Calcium signaling pathway
103672740 (KDR)
04151 PI3K-Akt signaling pathway
103672740 (KDR)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
103672740 (KDR)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
103672740 (KDR)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
103672740 (KDR)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
103672740 (KDR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
umr01001
]
103672740 (KDR)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
umr04090
]
103672740 (KDR)
Enzymes [BR:
umr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
103672740 (KDR)
Protein kinases [BR:
umr01001
]
Receptor tyrosine kinases (RTK)
VEGFR family [OT]
103672740 (KDR)
CD molecules [BR:
umr04090
]
Proteins
103672740 (KDR)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
VEGFR1-3_N_Ig-like
Ig_3
I-set
Pkinase
VEGFR-1-like_Ig-like
Ig_2
ig
Ig_VEGFR-1-like_5th
V-set
VEGFR-2_TMD
C2-set_2
Ig_4
V-set_CD47
Haspin_kinase
BppU_N
Motif
Other DBs
NCBI-GeneID:
103672740
NCBI-ProteinID:
XP_040481384
UniProt:
A0A8M1FLG9
LinkDB
All DBs
Position
Unknown
AA seq
1355 aa
AA seq
DB search
MESKALLAIALWLCVETRAASVGLPSVSLDPPRLSIQKDILTITANTTLQITCRGQRDLD
WLWPNNQSGSEKRVEVAECSDSLFCKTLTIPKVIGNDTGAYKCFYRDADTASVIYVYVQD
YRSPFIASVSDQHGVVYITENKNKTVVIPCLGSISNLNVSLCARYPEKRFVPDGHRISWD
SKKGFTIPSYMISYAGMVFCEAKINDESYQSIMYIVVVVGYKIYDVVLSPHHRVELSVGE
RLVLNCTARTELNVGIDFNWEYPSLKHQHKKLVNRDLKTQSGSEMKKFLSTLTIDGVTRS
DQGWYTCAASSGLMTKRNSTFVRVHEKPFVAFDSGMESLVEVTVGNRVEVPVKYLAYPTP
EIKWYKNGRPIESNHTIKGEKELIIMEVSEKDTGNYTVILTNPISKEKQSHVVSLLVNVP
PQIGEKSLISLVDSYQYGTTQTLTCTVYSVPPPHHIRWYWQLEECAYKPTQAVLMTNPYT
CKEWRDVDDFQGGNKIEVNKNQFALIEGKNKTVSTLVIQAANVSALYKCEAINKVGRGER
VISFHVTRGPEITLQPDTQPTERENVSLWCTADRTMFENLTWYKLGPHALPVHAGELPTP
VCKNLDALWKMNATKFSNGTSDILIMELQNASLRDQGDYVCFAQDRKTKKRHCVVRQLKV
LERVAPMITGNLENQTTSIGETIEVSCTTSGNPPPQVTWFKDNETLVEDSGIVLKDGNRN
LTIRRVRKEDEGLYTCQACSVLGCAKVEAFFIVEGAQEKTNLEVIILVGTAVIAMFFWLL
LVIVLRTVKRANGGELKTGYLSIVMDPDELPLDEHCERLPYDASKWEFPRDRLKLGKPLG
RGAFGQVIEADAFGIDKTATCKTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNL
LGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFVPYKSKGARFRQGKEYVGEITMDPKR
RLDSITSSQSSASSGFVEEKSLSDVEEEEVSEDLYKNFLTLEHLICYSFQVAKGMEFLAS
RKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRKGDARLPLKWMAPETIFDRV
YTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLD
CWHGEPNQRPTFSELVEHLGNLLQANAQQDGKDYIVLPIAETLSMEEDSGLSLPTSPVSC
MEEEEVCDPKFHYDNTAGISQYLQNSKRKSRPVSVKTFEDIPLEEPEVKVIPDDNQTDSG
MVLASEELKTLEDRTKLAPSFSGLMPSKSKESVASEGSNHTSGYQSGYHSDDTDTTVYSS
EEAELLKLMEIGPQAGSAAQILQPDSGPTLSSPPV
NT seq
4068 nt
NT seq
+upstream
nt +downstream
nt
atggagagcaaggcgctgctggccatcgctctgtggctctgcgtggagaccagggctgcc
tccgtgggtttgcctagtgtttcccttgatccacccagactcagcatacaaaaagacata
cttacaattacggctaatacaactcttcagattacttgcaggggacagagggacttggac
tggctctggcccaacaatcagagtggctctgagaaaagagtggaggtggccgagtgcagt
gatagcctcttctgtaagactcttacgattccaaaagtgattggaaatgatactggagcc
tacaagtgcttctatcgggacgctgacacggcctcggtcatttatgtctacgttcaagat
tacagatctccatttattgcttctgttagcgaccagcatggagttgtgtacatcactgag
aacaaaaacaaaactgtggtgattccatgtcttgggtccatttccaacctcaatgtgtca
ctttgtgcaaggtatccagaaaagaggtttgttcctgatggtcacagaatttcctgggac
agtaagaaaggctttactattcccagctacatgatcagctatgctggcatggtcttctgt
gaagcaaaaattaatgatgaaagttaccagtctattatgtacatagtggtggttgtaggg
tacaagatttatgatgtggtactcagcccccatcacagagttgagctgtctgttggagag
aggcttgtcttaaattgtacagcgaggactgaactaaatgtggggattgacttcaactgg
gaatacccttctttgaagcatcagcataaaaaacttgttaaccgggacctaaaaacccag
tctgggagtgagatgaagaaatttttgagcaccttgactatagatggtgtaacccggagt
gaccaaggctggtacacctgtgcagcttccagtgggctgatgaccaagcggaacagcaca
ttcgtcagggtccatgaaaaaccttttgttgcttttgatagtggcatggaatctttggtg
gaagtcacagtggggaaccgtgttgaagtccctgtgaagtacctggcttaccctaccccc
gaaataaaatggtataaaaatggaagacccattgaatccaatcacacaataaaaggggag
aaggaactaattattatggaagtgagtgaaaaagatacaggaaattatactgtcatcctc
accaaccccatttcaaaagagaaacagagccacgtggtatctctgcttgtgaatgtccca
ccccagatcggtgagaaatccctgatctctctggtggattcctaccagtacggcaccaca
caaaccctgacatgcacggtctactccgtccccccgccgcatcacattcgctggtattgg
cagctggaggagtgcgcctacaagcccacccaagctgtcttgatgacaaacccatatact
tgtaaggaatggagggatgtggatgacttccaggggggcaataaaattgaagtcaacaaa
aatcaatttgccctaattgaaggaaaaaacaaaactgtaagtacccttgttatccaagcg
gcaaatgtgtcagctttgtacaaatgtgaagccatcaacaaagttgggagaggagagagg
gtgatctccttccacgtgactcggggccctgaaatcactttgcaacctgacacccagccc
accgagcgggagaacgtgtccttgtggtgtactgcagacagaactatgtttgagaacctc
acgtggtacaagcttggcccacacgctctgccagtccatgcgggagagttgcccacacct
gtttgcaagaacttggatgctctttggaaaatgaacgccaccaagttttctaatggcaca
agtgacattttgatcatggagctccagaacgcatccttgcgggaccaaggagactatgtg
tgctttgctcaggacaggaagaccaagaaaagacattgtgtggtcagacagctcaaagtg
ttagagcgtgtggcgcccatgatcactggaaacctggagaatcagactacaagcattggg
gaaaccattgaagtctcatgcaccacgtctgggaatccccctccacaagttacgtggttt
aaagacaatgagacacttgtagaagactcaggaattgtactgaaagatgggaaccggaac
ctaaccatccgcagggtgaggaaggaggatgaaggcctctacacctgccaggcatgcagt
gtccttgggtgtgcaaaagtggaggcatttttcatagtagaaggtgcccaggagaagaca
aacttggaagtcattattctagtaggcacggcagtgattgccatgttcttctggttatta
cttgtcatcgttctacggaccgttaagcgggccaatggaggggaactgaagacaggctac
ttgtccatcgtcatggatccagatgagctccccttggatgagcactgtgagcgcctgcct
tacgatgccagcaaatgggagttccccagagaccggctgaaactaggtaagcctcttggc
cgtggtgcctttggccaagtgattgaagcagatgcctttggaatcgacaagacagcaact
tgcaagacagtggccgtcaaaatgttaaaagaaggagcaacacacagtgaacaccgagct
ctcatgtctgaactcaagatcctcattcatattggccaccatctcaatgtggtcaatctt
ctaggtgcctgtaccaagccaggagggccactcatggtgattgtggaattttgcaagttt
ggaaacttgtcgacttacttaaggagcaagagaaacgaatttgtcccctacaagagcaaa
ggggcacgattccgtcaagggaaagagtacgttggggagatcactatggatccgaaacgc
cgcttggacagtatcaccagtagtcagagctcagccagctctggatttgttgaggagaaa
tccctcagtgacgtggaggaagaggaagtttccgaagatctgtacaagaacttcctgacc
ttggagcacctcatctgctacagcttccaagtggctaagggcatggagtttttggcatcc
cggaagtgtatccacagggacctggcggcacgcaacatcctcctgtcggagaagaacgtg
gttaaaatctgtgactttggcttggcccgggatatttataaagacccagattatgtcaga
aaaggagatgctcgcctccctttgaaatggatggccccagaaacaatttttgacagagtg
tacacaattcagagtgatgtgtggtcttttggtgtcttgctctgggaaatattttcctta
ggtgcttctccgtatcctggagtaaagattgatgaggaattttgtaggcgattgaaagaa
ggcactagaatgagggcccctgattataccacaccagaaatgtaccagaccatgcttgac
tgctggcacggggagcccaatcagagacccacgttttcagagctggtggaacacttggga
aatctgttacaagctaatgctcagcaggatggcaaagactacattgttctcccgatagca
gagactttgagcatggaagaggattctggactctctctgcctacctcacctgtttcctgt
atggaggaagaggaagtgtgtgaccccaaattccattatgacaacacagcaggaatcagc
cagtatctgcagaacagtaagcgaaagagccggcctgtgagtgtaaaaacatttgaagat
atccctttggaagaaccagaagtaaaagtaatcccagatgacaaccagacggacagtggt
atggtcctggcatcagaagagctgaaaaccttggaagacagaaccaaattagctccatct
tttagtggactgatgcccagcaaaagcaaggagtctgtggcatccgaaggctctaaccac
acgagtggctaccagtctgggtatcactccgatgacacggacaccactgtgtactccagc
gaggaggccgaactgttaaagctgatggagattggaccacaagctggcagcgcagcccag
attctccagcctgactctgggcccacattgagctctcctcctgtttaa
DBGET
integrated database retrieval system
